The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:

"
GroEL-like equatorial domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
SC:160 kDa chaperonin60 kDa heat shock protein, mitochondrialChaperonin containing TCP1 subunit 2Thermosome subunit60 kDa chaperoninT-complex protein 1 subunit etaT-complex protein 1 subunit epsilonT-complex protein 1 subunit alphaT-complex protein 1 subunit betaT-complex protein 1 subunit zetaT-complex protein 1 subunit deltaT-complex protein 1 subunit gammaT-complex protein 1 theta subunitRuBisCO large subunit-binding protein subunit betaruBisCO large subunit-binding protein subunit alpha60 kDa chaperoninT-complex protein 1 subunit gamma60 kDa chaperoninT-complex protein 1 subunit etaT-complex protein 1, zeta subunitMcKusick-Kaufman/Bardet-Biedl syndromes putative chaperoninT-complex protein theta subunitChaperonin containing TCP1, subunit 5 (epsilon)T-complex protein 1 subunit zetaT-complex protein 1, beta subunitT-complex protein 1 subunit deltaT-complex protein 1 subunit zeta isoform X3Chaperonin 60 subunit alpha 2 chloroplasticT-complex protein 1 subunit gammaT-complex protein 1 subunit gammaChaperonin CPN60, mitochondrial60 kDa chaperonin60 kDa heat shock protein, mitochondrialHSPD1 isoform 460 kDa chaperoninT-complex protein 1 subunit gammaT-complex protein 1 subunit gammaT-complex protein 1, theta subunitT-complex protein 1 subunit gammaChaperonin containing TCP1 subunit 6BBardet-Biedl syndrome 10 proteinT-complex protein 1 subunit deltaT-complex polypeptide 1Heat shock protein family D (Hsp60) member 1Bardet-Biedl syndrome 12 proteinT-complex protein 1 subunit eta60 kDa chaperonin60 kDa chaperonin60 kDa chaperonin 1T-complex protein 1 subunitTheta, putativeBardet-Biedl syndrome 10 protein60 kDa chaperoninT-complex protein 1 subunit deltaChaperonin 1 60 kDaT-complex protein 1 subunit betaT-complex protein 1 beta subunit putative60 kDa chaperoninT-complex protein 1 subunit zetaUncharacterized protein60 kDa chaperonin60 kDa chaperonin GROELUncharacterized proteinT-complex protein 1 subunit gammaProbable T-complex protein 1 subunit thetaPredicted proteinUncharacterized proteinChaperonin 60GD22056T-complex protein 1 subunit gammaUncharacterized proteinTCP-1/cpn60 chaperonin family proteinMitochondrial chaperone TCM62T-complex protein 1 subunit gammaT-complex protein 1 subunit delta, putativeBardet-Biedl syndrome 10T-complex protein 1 subunit gammaChaperonin 60, putative60 kDa chaperonin60 kDa chaperoninTCP-1 chaperonin subunit beta60 kDa chaperoninMcKusick-Kaufman syndromeT-complex protein 1 subunit theta60 kDa chaperoninT-complex protein 1 subunit gammaBardet-Biedl syndrome 12Bardet-Biedl syndrome 12T-complex protein 1 delta subunit putativeT-complex protein 1, zeta subunit isoform 3-like proteinUncharacterized proteinT-complex protein 1 subunit etaUncharacterized protein60 kDa chaperonin 460 kDa chaperoninThermosome, alpha subunitMcKusick-Kaufman syndromeChaperonin, putativeT-complex protein 1 subunit eta60 kDa chaperonin 2Chaperonin 60 subunit alpha 2 chloroplasticUncharacterized proteinT-complex protein 1 subunit etaUncharacterized proteinPredicted proteinUncharacterized proteinUncharacterized proteinT-complex protein 1 subunit epsilonUncharacterized proteinUncharacterized proteinUncharacterized proteinT-complex protein 1 subunit zetaUncharacterized proteinChaperonin-containing TCP1 subunit 3Uncharacterized proteinUncharacterized proteinPutative GroEL-like chaperonine proteinMitochondrial chaperoninPredicted proteinUncharacterized proteinT-complex protein 1 subunit etaT-complex protein 1 subunit gammaTCP-1/cpn60 chaperonin family protein60 kDa chaperoninChaperonin-containing TCP1, subunit 2 (beta)T-complex protein 1 subunit etaUncharacterized proteinEukaryotic translation initiation factor 3 subunit ETCP-1/cpn60 chaperonin family proteinUncharacterized proteinUncharacterized proteinT-complex protein 1 subunit betaUncharacterized proteinUncharacterized proteinChaperonin Cpn60T-complex polypeptide 1T-complex protein 1 subunit alphaT-complex protein 1 subunit gammaChaperonin complex component, TCP-1 delta subunit, putativeUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinChaperonin 60 subunit alpha 2 chloroplastic60 kDa heat shock protein, mitochondrialUncharacterized proteinUncharacterized proteinRING-type E3 ubiquitin transferaseChaperonin-containing TCP1, subunit 6A (zeta 1)60 kDa heat shock protein, mitochondrialUncharacterized proteinT-complex protein 1 subunit gammaUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinT-complex protein 1 subunit deltaUncharacterized proteinT-complex protein 1 subunitTheta, putativeT-complex protein 1 subunit etaUncharacterized protein60 kDa heat shock protein, mitochondrial
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FunFam 48: 60 kDa chaperonin 1

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 1 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO TermAnnotationsEvidence
Single-stranded DNA binding GO:0003697
Interacting selectively and non-covalently with single-stranded DNA.
12 P9WPE9 (/IDA) P9WPE9 (/IDA) P9WPE9 (/IDA) P9WPE9 (/IDA) P9WPE9 (/IDA) P9WPE9 (/IDA) P9WPE9 (/IDA) P9WPE9 (/IDA) P9WPE9 (/IDA) P9WPE9 (/IDA)
(2 more)
Showing 1 to 1 of 1 entries

There are 5 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO TermAnnotationsEvidence
Response to heat GO:0009408
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism.
12 P9WPE9 (/IEP) P9WPE9 (/IEP) P9WPE9 (/IEP) P9WPE9 (/IEP) P9WPE9 (/IEP) P9WPE9 (/IEP) P9WPE9 (/IEP) P9WPE9 (/IEP) P9WPE9 (/IEP) P9WPE9 (/IEP)
(2 more)
Protein refolding GO:0042026
The process carried out by a cell that restores the biological activity of an unfolded or misfolded protein, using helper proteins such as chaperones.
12 P9WPE9 (/IDA) P9WPE9 (/IDA) P9WPE9 (/IDA) P9WPE9 (/IDA) P9WPE9 (/IDA) P9WPE9 (/IDA) P9WPE9 (/IDA) P9WPE9 (/IDA) P9WPE9 (/IDA) P9WPE9 (/IDA)
(2 more)
DNA protection GO:0042262
Any process in which DNA is protected from damage by, for example, oxidative stress.
12 P9WPE9 (/IDA) P9WPE9 (/IDA) P9WPE9 (/IDA) P9WPE9 (/IDA) P9WPE9 (/IDA) P9WPE9 (/IDA) P9WPE9 (/IDA) P9WPE9 (/IDA) P9WPE9 (/IDA) P9WPE9 (/IDA)
(2 more)
Nucleoid organization GO:0090143
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nucleoid. The nucleoid is the region of a bacterial cell, virion, mitochondrion or chloroplast to which the DNA is confined.
12 P9WPE9 (/IDA) P9WPE9 (/IDA) P9WPE9 (/IDA) P9WPE9 (/IDA) P9WPE9 (/IDA) P9WPE9 (/IDA) P9WPE9 (/IDA) P9WPE9 (/IDA) P9WPE9 (/IDA) P9WPE9 (/IDA)
(2 more)
Positive regulation of transcription regulatory region DNA binding GO:2000679
Any process that activates or increases the frequency, rate or extent of transcription regulatory region DNA binding.
12 P9WPE9 (/IDA) P9WPE9 (/IDA) P9WPE9 (/IDA) P9WPE9 (/IDA) P9WPE9 (/IDA) P9WPE9 (/IDA) P9WPE9 (/IDA) P9WPE9 (/IDA) P9WPE9 (/IDA) P9WPE9 (/IDA)
(2 more)
Showing 1 to 5 of 5 entries

There are 3 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO TermAnnotationsEvidence
Cell wall GO:0005618
The rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal, most prokaryotic cells and some protozoan parasites, maintaining their shape and protecting them from osmotic lysis. In plants it is made of cellulose and, often, lignin; in fungi it is composed largely of polysaccharides; in bacteria it is composed of peptidoglycan; in protozoan parasites such as Giardia species, it's made of carbohydrates and proteins.
12 P9WPE9 (/HDA) P9WPE9 (/HDA) P9WPE9 (/HDA) P9WPE9 (/HDA) P9WPE9 (/HDA) P9WPE9 (/HDA) P9WPE9 (/HDA) P9WPE9 (/HDA) P9WPE9 (/HDA) P9WPE9 (/HDA)
(2 more)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
12 P9WPE9 (/HDA) P9WPE9 (/HDA) P9WPE9 (/HDA) P9WPE9 (/HDA) P9WPE9 (/HDA) P9WPE9 (/HDA) P9WPE9 (/HDA) P9WPE9 (/HDA) P9WPE9 (/HDA) P9WPE9 (/HDA)
(2 more)
Bacterial nucleoid GO:0043590
The region of a bacterial cell to which the DNA is confined.
12 P9WPE9 (/IDA) P9WPE9 (/IDA) P9WPE9 (/IDA) P9WPE9 (/IDA) P9WPE9 (/IDA) P9WPE9 (/IDA) P9WPE9 (/IDA) P9WPE9 (/IDA) P9WPE9 (/IDA) P9WPE9 (/IDA)
(2 more)
Showing 1 to 3 of 3 entries
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