The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:

"
STAT transcription factor, N-terminal domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 2: Signal transducer and activator of transcription

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 25 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
DNA binding GO:0003677
Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
8 C0SPC8 (/IDA) P42230 (/IDA) P42230 (/IDA) P42232 (/IDA) P52632 (/IDA) Q68SP3 (/IDA) Q7T3T3 (/IDA) Q8UVW9 (/IDA)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
8 P42229 (/IPI) P42229 (/IPI) P42230 (/IPI) P42230 (/IPI) P42232 (/IPI) P51692 (/IPI) P52632 (/IPI) Q62771 (/IPI)
DNA binding GO:0003677
Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
7 O93378 (/ISS) O93378 (/ISS) P42231 (/ISS) Q95115 (/ISS) Q9TUM3 (/ISS) Q9TUZ0 (/ISS) Q9TUZ1 (/ISS)
DNA-binding transcription factor activity GO:0003700
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons.
6 C0SPC8 (/IDA) P52632 (/IDA) Q62771 (/IDA) Q68SP3 (/IDA) Q7T3T3 (/IDA) Q8UVW9 (/IDA)
DNA-binding transcription activator activity, RNA polymerase II-specific GO:0001228
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to activate or increase transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.
5 P42230 (/IDA) P42230 (/IDA) P42232 (/IDA) Q9JIA0 (/IDA) Q9JIA0 (/IDA)
Chromatin binding GO:0003682
Interacting selectively and non-covalently with chromatin, the network of fibers of DNA, protein, and sometimes RNA, that make up the chromosomes of the eukaryotic nucleus during interphase.
4 P42232 (/ISS) P51692 (/ISS) Q9TUM3 (/ISS) Q9TUZ0 (/ISS)
DNA-binding transcription factor activity GO:0003700
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons.
4 P42229 (/TAS) P42229 (/TAS) P51692 (/TAS) Q62771 (/TAS)
Sequence-specific DNA binding GO:0043565
Interacting selectively and non-covalently with DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding.
4 P42230 (/IDA) P42230 (/IDA) P52632 (/IDA) Q62771 (/IDA)
Protein dimerization activity GO:0046983
The formation of a protein dimer, a macromolecular structure consists of two noncovalently associated identical or nonidentical subunits.
4 P51692 (/ISS) P52632 (/ISS) Q9TUM3 (/ISS) Q9TUZ0 (/ISS)
RNA polymerase II proximal promoter sequence-specific DNA binding GO:0000978
Interacting selectively and non-covalently with a specific upstream regulatory DNA sequence (transcription factor recognition sequence or binding site) located in the proximal promoter of a gene transcribed by RNA polymerase II. The proximal promoter is in cis with and relatively close to the core promoter.
3 P42230 (/IDA) P42230 (/IDA) P42232 (/IDA)
DNA-binding transcription factor activity, RNA polymerase II-specific GO:0000981
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.
3 P42229 (/ISA) P42229 (/ISA) P51692 (/ISA)
DNA-binding transcription factor activity, RNA polymerase II-specific GO:0000981
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.
3 P42229 (/ISM) P42229 (/ISM) P51692 (/ISM)
DNA-binding transcription factor activity, RNA polymerase II-specific GO:0000981
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.
3 P42229 (/NAS) P42229 (/NAS) P51692 (/NAS)
Double-stranded DNA binding GO:0003690
Interacting selectively and non-covalently with double-stranded DNA.
3 P42230 (/ISO) P42230 (/ISO) P42232 (/ISO)
DNA-binding transcription factor activity GO:0003700
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons.
3 P42230 (/ISO) P42230 (/ISO) P42232 (/ISO)
Sequence-specific DNA binding GO:0043565
Interacting selectively and non-covalently with DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding.
3 P42230 (/ISO) P42230 (/ISO) P42232 (/ISO)
DNA-binding transcription activator activity, RNA polymerase II-specific GO:0001228
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to activate or increase transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.
2 P42230 (/IMP) P42230 (/IMP)
Double-stranded DNA binding GO:0003690
Interacting selectively and non-covalently with double-stranded DNA.
2 P52632 (/IDA) Q62771 (/IDA)
Phosphate ion binding GO:0042301
Interacting selectively and non-covalently with phosphate.
2 P42230 (/IDA) P42230 (/IDA)
DNA binding GO:0003677
Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
1 P42232 (/ISO)
Chromatin binding GO:0003682
Interacting selectively and non-covalently with chromatin, the network of fibers of DNA, protein, and sometimes RNA, that make up the chromosomes of the eukaryotic nucleus during interphase.
1 P52632 (/IDA)
Chromatin binding GO:0003682
Interacting selectively and non-covalently with chromatin, the network of fibers of DNA, protein, and sometimes RNA, that make up the chromosomes of the eukaryotic nucleus during interphase.
1 P42232 (/ISO)
Glucocorticoid receptor binding GO:0035259
Interacting selectively and non-covalently with a glucocorticoid receptor.
1 P51692 (/IPI)
Glucocorticoid receptor binding GO:0035259
Interacting selectively and non-covalently with a glucocorticoid receptor.
1 P42232 (/ISO)
Protein dimerization activity GO:0046983
The formation of a protein dimer, a macromolecular structure consists of two noncovalently associated identical or nonidentical subunits.
1 P42232 (/IDA)

There are 154 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Positive regulation of transcription by RNA polymerase II GO:0045944
Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
9 O93378 (/ISS) O93378 (/ISS) P42231 (/ISS) P51692 (/ISS) P52632 (/ISS) Q95115 (/ISS) Q9TUM3 (/ISS) Q9TUZ0 (/ISS) Q9TUZ1 (/ISS)
Natural killer cell differentiation GO:0001779
The process in which a relatively unspecialized cell acquires the specialized features of a natural killer cell.
7 O93378 (/ISS) O93378 (/ISS) P42231 (/ISS) Q95115 (/ISS) Q9TUM3 (/ISS) Q9TUZ0 (/ISS) Q9TUZ1 (/ISS)
Receptor signaling pathway via JAK-STAT GO:0007259
Any process in which STAT proteins (Signal Transducers and Activators of Transcription) and JAK (Janus Activated Kinase) proteins convey a signal to trigger a change in the activity or state of a cell. The receptor signaling pathway via JAK-STAT begins with activation of a receptor and proceeeds through STAT protein activation by members of the JAK family of tyrosine kinases. STAT proteins dimerize and subsequently translocate to the nucleus. The pathway ends with regulation of target gene expression by STAT proteins.
7 O93378 (/ISS) O93378 (/ISS) P42231 (/ISS) Q95115 (/ISS) Q9TUM3 (/ISS) Q9TUZ0 (/ISS) Q9TUZ1 (/ISS)
Positive regulation of cell population proliferation GO:0008284
Any process that activates or increases the rate or extent of cell proliferation.
7 O93378 (/ISS) O93378 (/ISS) P42231 (/ISS) Q95115 (/ISS) Q9TUM3 (/ISS) Q9TUZ0 (/ISS) Q9TUZ1 (/ISS)
Regulation of steroid metabolic process GO:0019218
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving steroids.
7 O93378 (/ISS) O93378 (/ISS) P42231 (/ISS) Q95115 (/ISS) Q9TUM3 (/ISS) Q9TUZ0 (/ISS) Q9TUZ1 (/ISS)
Cytokine-mediated signaling pathway GO:0019221
A series of molecular signals initiated by the binding of a cytokine to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.
7 O93378 (/ISS) O93378 (/ISS) P42231 (/ISS) Q95115 (/ISS) Q9TUM3 (/ISS) Q9TUZ0 (/ISS) Q9TUZ1 (/ISS)
Lipid storage GO:0019915
The accumulation and maintenance in cells or tissues of lipids, compounds soluble in organic solvents but insoluble or sparingly soluble in aqueous solvents. Lipid reserves can be accumulated during early developmental stages for mobilization and utilization at later stages of development.
7 O93378 (/ISS) O93378 (/ISS) P42231 (/ISS) Q95115 (/ISS) Q9TUM3 (/ISS) Q9TUZ0 (/ISS) Q9TUZ1 (/ISS)
Regulation of cell adhesion GO:0030155
Any process that modulates the frequency, rate or extent of attachment of a cell to another cell or to the extracellular matrix.
7 O93378 (/ISS) O93378 (/ISS) P42231 (/ISS) Q95115 (/ISS) Q9TUM3 (/ISS) Q9TUZ0 (/ISS) Q9TUZ1 (/ISS)
Regulation of epithelial cell differentiation GO:0030856
Any process that modulates the frequency, rate or extent of epithelial cell differentiation.
7 O93378 (/ISS) O93378 (/ISS) P42231 (/ISS) Q95115 (/ISS) Q9TUM3 (/ISS) Q9TUZ0 (/ISS) Q9TUZ1 (/ISS)
Positive regulation of multicellular organism growth GO:0040018
Any process that activates or increases the frequency, rate or extent of growth of an organism to reach its usual body size.
7 O93378 (/ISS) O93378 (/ISS) P42231 (/ISS) Q95115 (/ISS) Q9TUM3 (/ISS) Q9TUZ0 (/ISS) Q9TUZ1 (/ISS)
Positive regulation of activated T cell proliferation GO:0042104
Any process that activates or increases the rate or extent of activated T cell proliferation.
7 O93378 (/ISS) O93378 (/ISS) P42231 (/ISS) Q95115 (/ISS) Q9TUM3 (/ISS) Q9TUZ0 (/ISS) Q9TUZ1 (/ISS)
T cell homeostasis GO:0043029
The process of regulating the proliferation and elimination of T cells such that the total number of T cells within a whole or part of an organism is stable over time in the absence of an outside stimulus.
7 O93378 (/ISS) O93378 (/ISS) P42231 (/ISS) Q95115 (/ISS) Q9TUM3 (/ISS) Q9TUZ0 (/ISS) Q9TUZ1 (/ISS)
Negative regulation of apoptotic process GO:0043066
Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process.
7 O93378 (/ISS) O93378 (/ISS) P42231 (/ISS) Q95115 (/ISS) Q9TUM3 (/ISS) Q9TUZ0 (/ISS) Q9TUZ1 (/ISS)
Positive regulation of interleukin-2 biosynthetic process GO:0045086
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-2.
7 O93378 (/ISS) O93378 (/ISS) P42231 (/ISS) Q95115 (/ISS) Q9TUM3 (/ISS) Q9TUZ0 (/ISS) Q9TUZ1 (/ISS)
Positive regulation of B cell differentiation GO:0045579
Any process that activates or increases the frequency, rate or extent of B cell differentiation.
7 O93378 (/ISS) O93378 (/ISS) P42231 (/ISS) Q95115 (/ISS) Q9TUM3 (/ISS) Q9TUZ0 (/ISS) Q9TUZ1 (/ISS)
Negative regulation of erythrocyte differentiation GO:0045647
Any process that stops, prevents, or reduces the frequency, rate or extent of erythrocyte differentiation.
7 O93378 (/ISS) O93378 (/ISS) P42231 (/ISS) Q95115 (/ISS) Q9TUM3 (/ISS) Q9TUZ0 (/ISS) Q9TUZ1 (/ISS)
Positive regulation of mitotic cell cycle GO:0045931
Any process that activates or increases the rate or extent of progression through the mitotic cell cycle.
7 O93378 (/ISS) O93378 (/ISS) P42231 (/ISS) Q95115 (/ISS) Q9TUM3 (/ISS) Q9TUZ0 (/ISS) Q9TUZ1 (/ISS)
Positive regulation of transcription by RNA polymerase II GO:0045944
Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
7 C0SPC8 (/IDA) P42230 (/IDA) P42230 (/IDA) P42232 (/IDA) Q68SP3 (/IDA) Q7T3T3 (/IDA) Q8UVW9 (/IDA)
Development of secondary female sexual characteristics GO:0046543
The process whose specific outcome is the progression of the secondary female sexual characteristics over time, from their formation to the mature structures. In female humans, these include growth of axillary and pubic hair, breast development and menstrual periods. Their development occurs in response to sex hormone secretion.
7 O93378 (/ISS) O93378 (/ISS) P42231 (/ISS) Q95115 (/ISS) Q9TUM3 (/ISS) Q9TUZ0 (/ISS) Q9TUZ1 (/ISS)
Positive regulation of inflammatory response GO:0050729
Any process that activates or increases the frequency, rate or extent of the inflammatory response.
7 O93378 (/ISS) O93378 (/ISS) P42231 (/ISS) Q95115 (/ISS) Q9TUM3 (/ISS) Q9TUZ0 (/ISS) Q9TUZ1 (/ISS)
Luteinization GO:0001553
The set of processes resulting in differentiation of theca and granulosa cells into luteal cells and in the formation of a corpus luteum after ovulation.
5 P42231 (/ISS) Q95115 (/ISS) Q9TUM3 (/ISS) Q9TUZ0 (/ISS) Q9TUZ1 (/ISS)
Receptor signaling pathway via JAK-STAT GO:0007259
Any process in which STAT proteins (Signal Transducers and Activators of Transcription) and JAK (Janus Activated Kinase) proteins convey a signal to trigger a change in the activity or state of a cell. The receptor signaling pathway via JAK-STAT begins with activation of a receptor and proceeeds through STAT protein activation by members of the JAK family of tyrosine kinases. STAT proteins dimerize and subsequently translocate to the nucleus. The pathway ends with regulation of target gene expression by STAT proteins.
5 P42230 (/IDA) P42230 (/IDA) P42232 (/IDA) P52632 (/IDA) Q62771 (/IDA)
Female pregnancy GO:0007565
The set of physiological processes that allow an embryo or foetus to develop within the body of a female animal. It covers the time from fertilization of a female ovum by a male spermatozoon until birth.
5 P42231 (/ISS) Q95115 (/ISS) Q9TUM3 (/ISS) Q9TUZ0 (/ISS) Q9TUZ1 (/ISS)
Lactation GO:0007595
The regulated release of milk from the mammary glands and the period of time that a mother lactates to feed her young.
5 P42231 (/ISS) Q95115 (/ISS) Q9TUM3 (/ISS) Q9TUZ0 (/ISS) Q9TUZ1 (/ISS)
Receptor signaling pathway via JAK-STAT GO:0007259
Any process in which STAT proteins (Signal Transducers and Activators of Transcription) and JAK (Janus Activated Kinase) proteins convey a signal to trigger a change in the activity or state of a cell. The receptor signaling pathway via JAK-STAT begins with activation of a receptor and proceeeds through STAT protein activation by members of the JAK family of tyrosine kinases. STAT proteins dimerize and subsequently translocate to the nucleus. The pathway ends with regulation of target gene expression by STAT proteins.
4 C0SPC8 (/IGI) Q68SP3 (/IGI) Q7T3T3 (/IGI) Q8UVW9 (/IGI)
Receptor signaling pathway via JAK-STAT GO:0007259
Any process in which STAT proteins (Signal Transducers and Activators of Transcription) and JAK (Janus Activated Kinase) proteins convey a signal to trigger a change in the activity or state of a cell. The receptor signaling pathway via JAK-STAT begins with activation of a receptor and proceeeds through STAT protein activation by members of the JAK family of tyrosine kinases. STAT proteins dimerize and subsequently translocate to the nucleus. The pathway ends with regulation of target gene expression by STAT proteins.
4 C0SPC8 (/IMP) Q68SP3 (/IMP) Q7T3T3 (/IMP) Q8UVW9 (/IMP)
Lymphocyte differentiation GO:0030098
The process in which a relatively unspecialized precursor cell acquires specialized features of a lymphocyte. A lymphocyte is a leukocyte commonly found in the blood and lymph that has the characteristics of a large nucleus, a neutral staining cytoplasm, and prominent heterochromatin.
4 C0SPC8 (/IMP) Q68SP3 (/IMP) Q7T3T3 (/IMP) Q8UVW9 (/IMP)
Erythrocyte differentiation GO:0030218
The process in which a myeloid precursor cell acquires specializes features of an erythrocyte.
4 C0SPC8 (/IGI) Q68SP3 (/IGI) Q7T3T3 (/IGI) Q8UVW9 (/IGI)
Erythrocyte differentiation GO:0030218
The process in which a myeloid precursor cell acquires specializes features of an erythrocyte.
4 C0SPC8 (/IMP) Q68SP3 (/IMP) Q7T3T3 (/IMP) Q8UVW9 (/IMP)
Progesterone metabolic process GO:0042448
The chemical reactions and pathways involving progesterone, a steroid hormone produced in the ovary which prepares and maintains the uterus for pregnancy. Also found in plants.
4 O93378 (/ISS) O93378 (/ISS) Q9TUM3 (/ISS) Q9TUZ0 (/ISS)
Positive regulation of myeloid cell differentiation GO:0045639
Any process that activates or increases the frequency, rate or extent of myeloid cell differentiation.
4 C0SPC8 (/IMP) Q68SP3 (/IMP) Q7T3T3 (/IMP) Q8UVW9 (/IMP)
Positive regulation of erythrocyte differentiation GO:0045648
Any process that activates or increases the frequency, rate or extent of erythrocyte differentiation.
4 P42232 (/ISS) P52632 (/ISS) Q9TUM3 (/ISS) Q9TUZ0 (/ISS)
Development of secondary male sexual characteristics GO:0046544
The process whose specific outcome is the progression of the secondary male sexual characteristics over time, from their formation to the mature structures. In male humans, these include growth of axillary, chest, and pubic hair, voice changes, and testicular/penile enlargement. Development occurs in response to sex hormone secretion.
4 O93378 (/ISS) O93378 (/ISS) Q9TUM3 (/ISS) Q9TUZ0 (/ISS)
Developmental growth GO:0048589
The increase in size or mass of an entire organism, a part of an organism or a cell, where the increase in size or mass has the specific outcome of the progression of the organism over time from one condition to another.
4 C0SPC8 (/IMP) Q68SP3 (/IMP) Q7T3T3 (/IMP) Q8UVW9 (/IMP)
Erythrocyte development GO:0048821
The process whose specific outcome is the progression of an erythrocyte over time, from its formation to the mature structure.
4 C0SPC8 (/IMP) Q68SP3 (/IMP) Q7T3T3 (/IMP) Q8UVW9 (/IMP)
Growth hormone receptor signaling pathway via JAK-STAT GO:0060397
The process in which STAT proteins (Signal Transducers and Activators of Transcription) are activated by members of the JAK (janus activated kinase) family of tyrosine kinases, following the binding of physiological ligands to the growth hormone receptor. Once activated, STATs dimerize and translocate to the nucleus and modulate the expression of target genes.
4 P42230 (/IDA) P42230 (/IDA) P42232 (/IDA) P51692 (/IDA)
Cellular response to growth factor stimulus GO:0071363
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a growth factor stimulus.
4 P51692 (/ISS) P52632 (/ISS) Q9TUM3 (/ISS) Q9TUZ0 (/ISS)
Cellular response to epidermal growth factor stimulus GO:0071364
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an epidermal growth factor stimulus.
4 P42232 (/ISS) P51692 (/ISS) Q9TUM3 (/ISS) Q9TUZ0 (/ISS)
Luteinization GO:0001553
The set of processes resulting in differentiation of theca and granulosa cells into luteal cells and in the formation of a corpus luteum after ovulation.
3 P42230 (/IGI) P42230 (/IGI) P42232 (/IGI)
Natural killer cell differentiation GO:0001779
The process in which a relatively unspecialized cell acquires the specialized features of a natural killer cell.
3 P42230 (/IGI) P42230 (/IGI) P42232 (/IGI)
Regulation of transcription by RNA polymerase II GO:0006357
Any process that modulates the frequency, rate or extent of transcription mediated by RNA polymerase II.
3 P42230 (/IGI) P42230 (/IGI) P42232 (/IGI)
Regulation of transcription by RNA polymerase II GO:0006357
Any process that modulates the frequency, rate or extent of transcription mediated by RNA polymerase II.
3 P42229 (/TAS) P42229 (/TAS) P51692 (/TAS)
Transcription by RNA polymerase II GO:0006366
The synthesis of RNA from a DNA template by RNA polymerase II (RNAP II), originating at an RNA polymerase II promoter. Includes transcription of messenger RNA (mRNA) and certain small nuclear RNAs (snRNAs).
3 P42230 (/ISO) P42230 (/ISO) P42232 (/ISO)
Receptor signaling pathway via JAK-STAT GO:0007259
Any process in which STAT proteins (Signal Transducers and Activators of Transcription) and JAK (Janus Activated Kinase) proteins convey a signal to trigger a change in the activity or state of a cell. The receptor signaling pathway via JAK-STAT begins with activation of a receptor and proceeeds through STAT protein activation by members of the JAK family of tyrosine kinases. STAT proteins dimerize and subsequently translocate to the nucleus. The pathway ends with regulation of target gene expression by STAT proteins.
3 P42230 (/ISO) P42230 (/ISO) P42232 (/ISO)
Receptor signaling pathway via JAK-STAT GO:0007259
Any process in which STAT proteins (Signal Transducers and Activators of Transcription) and JAK (Janus Activated Kinase) proteins convey a signal to trigger a change in the activity or state of a cell. The receptor signaling pathway via JAK-STAT begins with activation of a receptor and proceeeds through STAT protein activation by members of the JAK family of tyrosine kinases. STAT proteins dimerize and subsequently translocate to the nucleus. The pathway ends with regulation of target gene expression by STAT proteins.
3 P42229 (/TAS) P42229 (/TAS) P51692 (/TAS)
Female pregnancy GO:0007565
The set of physiological processes that allow an embryo or foetus to develop within the body of a female animal. It covers the time from fertilization of a female ovum by a male spermatozoon until birth.
3 P42230 (/IGI) P42230 (/IGI) P42232 (/IGI)
Lactation GO:0007595
The regulated release of milk from the mammary glands and the period of time that a mother lactates to feed her young.
3 P42230 (/IMP) P42230 (/IMP) P42232 (/IMP)
Positive regulation of cell population proliferation GO:0008284
Any process that activates or increases the rate or extent of cell proliferation.
3 P42230 (/IGI) P42230 (/IGI) P42232 (/IGI)
Regulation of steroid metabolic process GO:0019218
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving steroids.
3 P42230 (/IGI) P42230 (/IGI) P42232 (/IGI)
Cytokine-mediated signaling pathway GO:0019221
A series of molecular signals initiated by the binding of a cytokine to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.
3 P42230 (/IDA) P42230 (/IDA) P42232 (/IDA)
Cytokine-mediated signaling pathway GO:0019221
A series of molecular signals initiated by the binding of a cytokine to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.
3 P42229 (/TAS) P42229 (/TAS) P51692 (/TAS)
Taurine metabolic process GO:0019530
The chemical reactions and pathways involving taurine (2-aminoethanesulfonic acid), a sulphur-containing amino acid derivative important in the metabolism of fats.
3 P42230 (/IGI) P42230 (/IGI) P42232 (/IGI)
Taurine metabolic process GO:0019530
The chemical reactions and pathways involving taurine (2-aminoethanesulfonic acid), a sulphur-containing amino acid derivative important in the metabolism of fats.
3 P42229 (/ISS) P42229 (/ISS) P51692 (/ISS)
Lipid storage GO:0019915
The accumulation and maintenance in cells or tissues of lipids, compounds soluble in organic solvents but insoluble or sparingly soluble in aqueous solvents. Lipid reserves can be accumulated during early developmental stages for mobilization and utilization at later stages of development.
3 P42230 (/IGI) P42230 (/IGI) P42232 (/IGI)
Regulation of cell adhesion GO:0030155
Any process that modulates the frequency, rate or extent of attachment of a cell to another cell or to the extracellular matrix.
3 P42230 (/IMP) P42230 (/IMP) P42232 (/IMP)
Regulation of epithelial cell differentiation GO:0030856
Any process that modulates the frequency, rate or extent of epithelial cell differentiation.
3 P42230 (/IMP) P42230 (/IMP) P42232 (/IMP)
Mammary gland development GO:0030879
The process whose specific outcome is the progression of the mammary gland over time, from its formation to the mature structure. The mammary gland is a large compound sebaceous gland that in female mammals is modified to secrete milk. Its development starts with the formation of the mammary line and ends as the mature gland cycles between nursing and weaning stages.
3 P42231 (/ISS) Q95115 (/ISS) Q9TUZ1 (/ISS)
Positive regulation of natural killer cell differentiation GO:0032825
Any process that activates or increases the frequency, rate or extent of natural killer cell differentiation.
3 P42230 (/IMP) P42230 (/IMP) P42232 (/IMP)
T cell differentiation in thymus GO:0033077
The process in which a precursor cell type acquires the specialized features of a T cell via a differentiation pathway dependent upon transit through the thymus.
3 P42230 (/IGI) P42230 (/IGI) P42232 (/IGI)
Interleukin-15-mediated signaling pathway GO:0035723
A series of molecular signals initiated by the binding of interleukin-15 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.
3 P42229 (/TAS) P42229 (/TAS) P51692 (/TAS)
Interleukin-2-mediated signaling pathway GO:0038110
A series of molecular signals initiated by the binding of interleukin-2 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.
3 P42229 (/TAS) P42229 (/TAS) P51692 (/TAS)
Interleukin-7-mediated signaling pathway GO:0038111
A series of molecular signals initiated by the binding of interleukin-7 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.
3 P42229 (/TAS) P42229 (/TAS) P51692 (/TAS)
Interleukin-9-mediated signaling pathway GO:0038113
A series of molecular signals initiated by the binding of interleukin-9 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.
3 P42229 (/TAS) P42229 (/TAS) P51692 (/TAS)
Regulation of multicellular organism growth GO:0040014
Any process that modulates the frequency, rate or extent of growth of the body of an organism so that it reaches its usual body size.
3 P42230 (/IGI) P42230 (/IGI) P42232 (/IGI)
Regulation of multicellular organism growth GO:0040014
Any process that modulates the frequency, rate or extent of growth of the body of an organism so that it reaches its usual body size.
3 P42229 (/ISS) P42229 (/ISS) P51692 (/ISS)
Positive regulation of multicellular organism growth GO:0040018
Any process that activates or increases the frequency, rate or extent of growth of an organism to reach its usual body size.
3 P42230 (/IGI) P42230 (/IGI) P42232 (/IGI)
Positive regulation of activated T cell proliferation GO:0042104
Any process that activates or increases the rate or extent of activated T cell proliferation.
3 P42230 (/IGI) P42230 (/IGI) P42232 (/IGI)
T cell homeostasis GO:0043029
The process of regulating the proliferation and elimination of T cells such that the total number of T cells within a whole or part of an organism is stable over time in the absence of an outside stimulus.
3 P42230 (/IGI) P42230 (/IGI) P42232 (/IGI)
Negative regulation of apoptotic process GO:0043066
Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process.
3 P42230 (/IGI) P42230 (/IGI) P42232 (/IGI)
Response to peptide hormone GO:0043434
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a peptide hormone stimulus. A peptide hormone is any of a class of peptides that are secreted into the blood stream and have endocrine functions in living animals.
3 P42230 (/IDA) P42230 (/IDA) P52632 (/IDA)
Positive regulation of interleukin-2 biosynthetic process GO:0045086
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-2.
3 P42230 (/IGI) P42230 (/IGI) P42232 (/IGI)
Positive regulation of B cell differentiation GO:0045579
Any process that activates or increases the frequency, rate or extent of B cell differentiation.
3 P42230 (/IGI) P42230 (/IGI) P42232 (/IGI)
Positive regulation of gamma-delta T cell differentiation GO:0045588
Any process that activates or increases the frequency, rate or extent of gamma-delta T cell differentiation.
3 P42230 (/IGI) P42230 (/IGI) P42232 (/IGI)
Positive regulation of lymphocyte differentiation GO:0045621
Any process that activates or increases the frequency, rate or extent of lymphocyte differentiation.
3 P42230 (/IGI) P42230 (/IGI) P42232 (/IGI)
Negative regulation of erythrocyte differentiation GO:0045647
Any process that stops, prevents, or reduces the frequency, rate or extent of erythrocyte differentiation.
3 P42230 (/IGI) P42230 (/IGI) P42232 (/IGI)
Positive regulation of mitotic cell cycle GO:0045931
Any process that activates or increases the rate or extent of progression through the mitotic cell cycle.
3 P42230 (/IGI) P42230 (/IGI) P42232 (/IGI)
Positive regulation of transcription by RNA polymerase II GO:0045944
Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
3 P42230 (/IGI) P42230 (/IGI) P42232 (/IGI)
Positive regulation of transcription by RNA polymerase II GO:0045944
Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
3 P42230 (/IMP) P42230 (/IMP) P42232 (/IMP)
Positive regulation of natural killer cell mediated cytotoxicity GO:0045954
Any process that activates or increases the frequency, rate or extent of natural killer cell mediated cytotoxicity.
3 P42230 (/IMP) P42230 (/IMP) P42232 (/IMP)
Development of secondary female sexual characteristics GO:0046543
The process whose specific outcome is the progression of the secondary female sexual characteristics over time, from their formation to the mature structures. In female humans, these include growth of axillary and pubic hair, breast development and menstrual periods. Their development occurs in response to sex hormone secretion.
3 P42230 (/IMP) P42230 (/IMP) P42232 (/IMP)
Development of secondary male sexual characteristics GO:0046544
The process whose specific outcome is the progression of the secondary male sexual characteristics over time, from their formation to the mature structures. In male humans, these include growth of axillary, chest, and pubic hair, voice changes, and testicular/penile enlargement. Development occurs in response to sex hormone secretion.
3 P42230 (/IGI) P42230 (/IGI) P42232 (/IGI)
Development of secondary male sexual characteristics GO:0046544
The process whose specific outcome is the progression of the secondary male sexual characteristics over time, from their formation to the mature structures. In male humans, these include growth of axillary, chest, and pubic hair, voice changes, and testicular/penile enlargement. Development occurs in response to sex hormone secretion.
3 P42230 (/IMP) P42230 (/IMP) P42232 (/IMP)
Peyer's patch development GO:0048541
The process whose specific outcome is the progression of Peyer's patches over time, from their formation to the mature structure. Peyer's patches are typically found as nodules associated with gut epithelium with distinct internal structures including B- and T-zones for the activation of lymphocytes.
3 P42230 (/IGI) P42230 (/IGI) P42232 (/IGI)
Positive regulation of inflammatory response GO:0050729
Any process that activates or increases the frequency, rate or extent of the inflammatory response.
3 P42230 (/IGI) P42230 (/IGI) P42232 (/IGI)
Growth hormone receptor signaling pathway via JAK-STAT GO:0060397
The process in which STAT proteins (Signal Transducers and Activators of Transcription) are activated by members of the JAK (janus activated kinase) family of tyrosine kinases, following the binding of physiological ligands to the growth hormone receptor. Once activated, STATs dimerize and translocate to the nucleus and modulate the expression of target genes.
3 P42229 (/TAS) P42229 (/TAS) P51692 (/TAS)
Positive regulation of endothelial cell proliferation GO:0001938
Any process that activates or increases the rate or extent of endothelial cell proliferation.
2 P42229 (/IMP) P42229 (/IMP)
Positive regulation of endothelial cell proliferation GO:0001938
Any process that activates or increases the rate or extent of endothelial cell proliferation.
2 P42230 (/ISO) P42230 (/ISO)
Regulation of transcription by RNA polymerase II GO:0006357
Any process that modulates the frequency, rate or extent of transcription mediated by RNA polymerase II.
2 P42230 (/IDA) P42230 (/IDA)
Transcription by RNA polymerase II GO:0006366
The synthesis of RNA from a DNA template by RNA polymerase II (RNAP II), originating at an RNA polymerase II promoter. Includes transcription of messenger RNA (mRNA) and certain small nuclear RNAs (snRNAs).
2 P52632 (/IDA) Q62771 (/IDA)
Positive regulation of cell population proliferation GO:0008284
Any process that activates or increases the rate or extent of cell proliferation.
2 P42230 (/IDA) P42230 (/IDA)
Peptidyl-tyrosine phosphorylation GO:0018108
The phosphorylation of peptidyl-tyrosine to form peptidyl-O4'-phospho-L-tyrosine.
2 P42230 (/IDA) P42230 (/IDA)
Mammary gland development GO:0030879
The process whose specific outcome is the progression of the mammary gland over time, from its formation to the mature structure. The mammary gland is a large compound sebaceous gland that in female mammals is modified to secrete milk. Its development starts with the formation of the mammary line and ends as the mature gland cycles between nursing and weaning stages.
2 P42230 (/IMP) P42230 (/IMP)
Negative regulation of mast cell apoptotic process GO:0033026
Any process that stops, prevents, or reduces the frequency, rate, or extent of mast cell apoptotic process.
2 P42230 (/IMP) P42230 (/IMP)
Reelin-mediated signaling pathway GO:0038026
A series of molecular signals initiated by the binding of reelin (a secreted glycoprotein) to a receptor on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription.
2 P42229 (/IDA) P42229 (/IDA)
Reelin-mediated signaling pathway GO:0038026
A series of molecular signals initiated by the binding of reelin (a secreted glycoprotein) to a receptor on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription.
2 P42230 (/ISO) P42230 (/ISO)
Positive regulation of activated T cell proliferation GO:0042104
Any process that activates or increases the rate or extent of activated T cell proliferation.
2 P42230 (/IDA) P42230 (/IDA)
Positive regulation of blood vessel endothelial cell migration GO:0043536
Any process that activates or increases the frequency, rate or extent of the migration of the endothelial cells of blood vessels.
2 P42229 (/IMP) P42229 (/IMP)
Positive regulation of blood vessel endothelial cell migration GO:0043536
Any process that activates or increases the frequency, rate or extent of the migration of the endothelial cells of blood vessels.
2 P42230 (/ISO) P42230 (/ISO)
Response to ethanol GO:0045471
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ethanol stimulus.
2 P52632 (/IEP) Q62771 (/IEP)
Mammary gland involution GO:0060056
The tissue remodeling that removes differentiated mammary epithelia during weaning.
2 P42230 (/ISO) P42230 (/ISO)
Positive regulation of mast cell differentiation GO:0060376
Any process that increases the rate, frequency or extent of mast cell differentiation, the process in which a relatively unspecialized myeloid precursor cell acquires the specialized features of a mast cell. A mast cell is a cell that is found in almost all tissues containing numerous basophilic granules and capable of releasing large amounts of histamine and heparin upon activation.
2 P42230 (/IMP) P42230 (/IMP)
Prostate gland epithelium morphogenesis GO:0060740
The process in which the anatomical structures of epithelia of the prostate gland are generated and organized. An epithelium consists of closely packed cells arranged in one or more layers, that covers the outer surfaces of the body or lines any internal cavity or tube.
2 P42230 (/IMP) P42230 (/IMP)
Epithelial cell differentiation involved in prostate gland development GO:0060742
The process in which a relatively unspecialized cell acquires specialized features of an epithelial cell of the prostate gland.
2 P42230 (/IMP) P42230 (/IMP)
Mammary gland epithelium development GO:0061180
The process whose specific outcome is the progression of the mammary gland epithelium over time, from its formation to the mature structure. The mammary gland is a large compound sebaceous gland that in female mammals is modified to secrete milk.
2 P42230 (/IGI) P42230 (/IGI)
Mammary gland epithelium development GO:0061180
The process whose specific outcome is the progression of the mammary gland epithelium over time, from its formation to the mature structure. The mammary gland is a large compound sebaceous gland that in female mammals is modified to secrete milk.
2 P42230 (/IMP) P42230 (/IMP)
Positive regulation of mast cell proliferation GO:0070668
Any process that activates or increases the rate or extent of mast cell proliferation.
2 P42230 (/IMP) P42230 (/IMP)
Cellular response to cytokine stimulus GO:0071345
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cytokine stimulus.
2 P42230 (/ISO) P42230 (/ISO)
Cellular response to organic cyclic compound GO:0071407
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organic cyclic compound stimulus.
2 P42230 (/ISO) P42230 (/ISO)
Cellular response to granulocyte macrophage colony-stimulating factor stimulus GO:0097011
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a granulocyte macrophage colony-stimulating factor stimulus.
2 P42230 (/IDA) P42230 (/IDA)
Luteinization GO:0001553
The set of processes resulting in differentiation of theca and granulosa cells into luteal cells and in the formation of a corpus luteum after ovulation.
1 P52632 (/IDA)
Luteinization GO:0001553
The set of processes resulting in differentiation of theca and granulosa cells into luteal cells and in the formation of a corpus luteum after ovulation.
1 P42232 (/ISO)
Response to hypoxia GO:0001666
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating lowered oxygen tension. Hypoxia, defined as a decline in O2 levels below normoxic levels of 20.8 - 20.95%, results in metabolic adaptation at both the cellular and organismal level.
1 P52632 (/IEP)
Liver development GO:0001889
The process whose specific outcome is the progression of the liver over time, from its formation to the mature structure. The liver is an exocrine gland which secretes bile and functions in metabolism of protein and carbohydrate and fat, synthesizes substances involved in the clotting of the blood, synthesizes vitamin A, detoxifies poisonous substances, stores glycogen, and breaks down worn-out erythrocytes.
1 P52632 (/IDA)
Liver development GO:0001889
The process whose specific outcome is the progression of the liver over time, from its formation to the mature structure. The liver is an exocrine gland which secretes bile and functions in metabolism of protein and carbohydrate and fat, synthesizes substances involved in the clotting of the blood, synthesizes vitamin A, detoxifies poisonous substances, stores glycogen, and breaks down worn-out erythrocytes.
1 P42232 (/ISO)
Regulation of transcription, DNA-templated GO:0006355
Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.
1 P52632 (/IDA)
Regulation of transcription, DNA-templated GO:0006355
Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.
1 P42232 (/ISO)
Regulation of transcription, DNA-templated GO:0006355
Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.
1 Q62771 (/TAS)
Acute-phase response GO:0006953
An acute inflammatory response that involves non-antibody proteins whose concentrations in the plasma increase in response to infection or injury of homeothermic animals.
1 P52632 (/IDA)
Acute-phase response GO:0006953
An acute inflammatory response that involves non-antibody proteins whose concentrations in the plasma increase in response to infection or injury of homeothermic animals.
1 P42232 (/ISO)
Sex differentiation GO:0007548
The establishment of the sex of an organism by physical differentiation.
1 P42232 (/IMP)
Female pregnancy GO:0007565
The set of physiological processes that allow an embryo or foetus to develop within the body of a female animal. It covers the time from fertilization of a female ovum by a male spermatozoon until birth.
1 P42232 (/IMP)
Lactation GO:0007595
The regulated release of milk from the mammary glands and the period of time that a mother lactates to feed her young.
1 Q62771 (/IEP)
Response to nutrient levels GO:0031667
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting the presence, absence, or concentration of nutrients.
1 Q62771 (/IEP)
Response to estradiol GO:0032355
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of stimulus by estradiol, a C18 steroid hormone hydroxylated at C3 and C17 that acts as a potent estrogen.
1 P51692 (/IDA)
Response to estradiol GO:0032355
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of stimulus by estradiol, a C18 steroid hormone hydroxylated at C3 and C17 that acts as a potent estrogen.
1 P42232 (/ISO)
Response to lipopolysaccharide GO:0032496
Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipopolysaccharide stimulus; lipopolysaccharide is a major component of the cell wall of gram-negative bacteria.
1 P52632 (/IDA)
Response to lipopolysaccharide GO:0032496
Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipopolysaccharide stimulus; lipopolysaccharide is a major component of the cell wall of gram-negative bacteria.
1 P42232 (/ISO)
Positive regulation of natural killer cell proliferation GO:0032819
Any process that activates or increases the frequency, rate or extent of natural killer cell proliferation.
1 P42232 (/IMP)
Cellular response to hormone stimulus GO:0032870
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hormone stimulus.
1 P51692 (/IDA)
Cellular response to hormone stimulus GO:0032870
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hormone stimulus.
1 P42232 (/ISO)
Positive regulation of multicellular organism growth GO:0040018
Any process that activates or increases the frequency, rate or extent of growth of an organism to reach its usual body size.
1 P42232 (/IMP)
Positive regulation of activated T cell proliferation GO:0042104
Any process that activates or increases the rate or extent of activated T cell proliferation.
1 P42232 (/IMP)
Progesterone metabolic process GO:0042448
The chemical reactions and pathways involving progesterone, a steroid hormone produced in the ovary which prepares and maintains the uterus for pregnancy. Also found in plants.
1 P42232 (/IGI)
Response to peptide hormone GO:0043434
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a peptide hormone stimulus. A peptide hormone is any of a class of peptides that are secreted into the blood stream and have endocrine functions in living animals.
1 P52632 (/IEP)
Response to peptide hormone GO:0043434
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a peptide hormone stimulus. A peptide hormone is any of a class of peptides that are secreted into the blood stream and have endocrine functions in living animals.
1 P42232 (/ISO)
Response to estrogen GO:0043627
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of stimulus by an estrogen, C18 steroid hormones that can stimulate the development of female sexual characteristics.
1 Q9DG74 (/IDA)
Positive regulation of erythrocyte differentiation GO:0045648
Any process that activates or increases the frequency, rate or extent of erythrocyte differentiation.
1 P51692 (/IDA)
Positive regulation of erythrocyte differentiation GO:0045648
Any process that activates or increases the frequency, rate or extent of erythrocyte differentiation.
1 P42232 (/ISO)
Multicellular organismal reproductive process GO:0048609
The process, occurring above the cellular level, that is pertinent to the reproductive function of a multicellular organism. This includes the integrated processes at the level of tissues and organs.
1 Q62771 (/IEP)
Positive regulation of smooth muscle cell proliferation GO:0048661
Any process that activates or increases the rate or extent of smooth muscle cell proliferation.
1 P52632 (/IMP)
Positive regulation of smooth muscle cell proliferation GO:0048661
Any process that activates or increases the rate or extent of smooth muscle cell proliferation.
1 P42232 (/ISO)
Positive regulation of cellular component movement GO:0051272
Any process that activates or increases the frequency, rate or extent of the movement of a cellular component.
1 P52632 (/IMP)
Positive regulation of cellular component movement GO:0051272
Any process that activates or increases the frequency, rate or extent of the movement of a cellular component.
1 P42232 (/ISO)
Mammary gland involution GO:0060056
The tissue remodeling that removes differentiated mammary epithelia during weaning.
1 Q62771 (/IDA)
Growth hormone receptor signaling pathway via JAK-STAT GO:0060397
The process in which STAT proteins (Signal Transducers and Activators of Transcription) are activated by members of the JAK (janus activated kinase) family of tyrosine kinases, following the binding of physiological ligands to the growth hormone receptor. Once activated, STATs dimerize and translocate to the nucleus and modulate the expression of target genes.
1 P42232 (/ISO)
Response to interleukin-2 GO:0070669
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-2 stimulus.
1 P42232 (/IMP)
Response to interleukin-4 GO:0070670
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-4 stimulus.
1 P42232 (/IMP)
Response to interleukin-15 GO:0070672
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-15 stimulus.
1 P42232 (/IMP)
Cellular response to cytokine stimulus GO:0071345
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cytokine stimulus.
1 Q62771 (/IDA)
Cellular response to growth factor stimulus GO:0071363
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a growth factor stimulus.
1 P42232 (/IDA)
Cellular response to epidermal growth factor stimulus GO:0071364
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an epidermal growth factor stimulus.
1 P52632 (/IDA)
Cellular response to epidermal growth factor stimulus GO:0071364
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an epidermal growth factor stimulus.
1 P42232 (/ISO)
Cellular response to organic cyclic compound GO:0071407
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organic cyclic compound stimulus.
1 Q62771 (/IDA)
Mast cell migration GO:0097531
The movement of a mast cell within or between different tissues and organs of the body.
1 P42232 (/IMP)

There are 12 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
9 O93378 (/ISS) O93378 (/ISS) P42231 (/ISS) P51692 (/ISS) P52632 (/ISS) Q95115 (/ISS) Q9TUM3 (/ISS) Q9TUZ0 (/ISS) Q9TUZ1 (/ISS)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
8 O93378 (/ISS) O93378 (/ISS) P42231 (/ISS) P51692 (/ISS) Q95115 (/ISS) Q9TUM3 (/ISS) Q9TUZ0 (/ISS) Q9TUZ1 (/ISS)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
8 P42229 (/TAS) P42229 (/TAS) P42230 (/TAS) P42230 (/TAS) P42232 (/TAS) P51692 (/TAS) P52632 (/TAS) Q62771 (/TAS)
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
6 P42229 (/TAS) P42229 (/TAS) P42230 (/TAS) P42230 (/TAS) P42232 (/TAS) P51692 (/TAS)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
5 P42230 (/IDA) P42230 (/IDA) P42232 (/IDA) P52632 (/IDA) Q62771 (/IDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
4 P42230 (/IDA) P42230 (/IDA) P42232 (/IDA) Q62771 (/IDA)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
4 K7EK35 (/IDA) P42229 (/IDA) P42229 (/IDA) P52632 (/IDA)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
3 P42230 (/ISO) P42230 (/ISO) P42232 (/ISO)
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
3 K7EK35 (/IDA) P42229 (/IDA) P42229 (/IDA)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
3 P42230 (/ISO) P42230 (/ISO) P42232 (/ISO)
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
2 P42230 (/ISO) P42230 (/ISO)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
2 P42230 (/ISO) P42230 (/ISO)
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