The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:

"
N-terminal domain of the delta subunit of the F1F0-ATP synthase
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 2: ATP synthase subunit O, mitochondrial

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 13 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
3 P48047 (/IPI) P48047 (/IPI) P48047 (/IPI)
Drug binding GO:0008144
Interacting selectively and non-covalently with a drug, any naturally occurring or synthetic substance, other than a nutrient, that, when administered or applied to an organism, affects the structure or functioning of the organism; in particular, any such substance used in the diagnosis, prevention, or treatment of disease.
3 P48047 (/IDA) P48047 (/IDA) P48047 (/IDA)
ATPase activity GO:0016887
Catalysis of the reaction: ATP + H2O = ADP + phosphate + 2 H+. May or may not be coupled to another reaction.
3 P48047 (/IDA) P48047 (/IDA) P48047 (/IDA)
Transmembrane transporter activity GO:0022857
Enables the transfer of a substance, usually a specific substance or a group of related substances, from one side of a membrane to the other.
3 P48047 (/IC) P48047 (/IC) P48047 (/IC)
Drug binding GO:0008144
Interacting selectively and non-covalently with a drug, any naturally occurring or synthetic substance, other than a nutrient, that, when administered or applied to an organism, affects the structure or functioning of the organism; in particular, any such substance used in the diagnosis, prevention, or treatment of disease.
2 Q9DB20 (/ISO) Q9DB20 (/ISO)
ATPase activity GO:0016887
Catalysis of the reaction: ATP + H2O = ADP + phosphate + 2 H+. May or may not be coupled to another reaction.
2 Q9DB20 (/ISO) Q9DB20 (/ISO)
Protein-containing complex binding GO:0044877
Interacting selectively and non-covalently with a macromolecular complex.
2 Q9DB20 (/ISO) Q9DB20 (/ISO)
Estradiol binding GO:1903924
Interacting selectively and non-covalently with estradiol.
2 Q9DB20 (/ISO) Q9DB20 (/ISO)
Structural molecule activity GO:0005198
The action of a molecule that contributes to the structural integrity of a complex or its assembly within or outside a cell.
1 O74479 (/ISO)
Zinc ion binding GO:0008270
Interacting selectively and non-covalently with zinc (Zn) ions.
1 Q96251 (/IDA)
Protein-containing complex binding GO:0044877
Interacting selectively and non-covalently with a macromolecular complex.
1 Q06647 (/IDA)
Cobalt ion binding GO:0050897
Interacting selectively and non-covalently with a cobalt (Co) ion.
1 Q96251 (/IDA)
Estradiol binding GO:1903924
Interacting selectively and non-covalently with estradiol.
1 Q06647 (/IDA)

There are 16 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
ATP synthesis coupled proton transport GO:0015986
The transport of protons across a membrane to generate an electrochemical gradient (proton-motive force) that powers ATP synthesis.
9 P09457 (/IDA) P09457 (/IDA) P09457 (/IDA) P09457 (/IDA) P09457 (/IDA) P09457 (/IDA) P09457 (/IDA) P09457 (/IDA) P09457 (/IDA)
ATP synthesis coupled proton transport GO:0015986
The transport of protons across a membrane to generate an electrochemical gradient (proton-motive force) that powers ATP synthesis.
9 P09457 (/IMP) P09457 (/IMP) P09457 (/IMP) P09457 (/IMP) P09457 (/IMP) P09457 (/IMP) P09457 (/IMP) P09457 (/IMP) P09457 (/IMP)
Mitochondrial ATP synthesis coupled proton transport GO:0042776
The transport of protons across a mitochondrial membrane to generate an electrochemical gradient (proton-motive force) that powers ATP synthesis.
5 P48047 (/IMP) P48047 (/IMP) P48047 (/IMP) P91283 (/IMP) Q7JNG1 (/IMP)
ATP biosynthetic process GO:0006754
The chemical reactions and pathways resulting in the formation of ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
3 P48047 (/NAS) P48047 (/NAS) P48047 (/NAS)
ATP biosynthetic process GO:0006754
The chemical reactions and pathways resulting in the formation of ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
3 P48047 (/TAS) P48047 (/TAS) P48047 (/TAS)
Cristae formation GO:0042407
The assembly of cristae, the inwards folds of the inner mitochondrial membrane.
3 P48047 (/TAS) P48047 (/TAS) P48047 (/TAS)
Mitochondrial ATP synthesis coupled proton transport GO:0042776
The transport of protons across a mitochondrial membrane to generate an electrochemical gradient (proton-motive force) that powers ATP synthesis.
3 O74479 (/ISO) Q9DB20 (/ISO) Q9DB20 (/ISO)
Mitochondrial ATP synthesis coupled proton transport GO:0042776
The transport of protons across a mitochondrial membrane to generate an electrochemical gradient (proton-motive force) that powers ATP synthesis.
3 P48047 (/TAS) P48047 (/TAS) P48047 (/TAS)
Proton transmembrane transport GO:1902600
The directed movement of a proton across a membrane.
3 P48047 (/NAS) P48047 (/NAS) P48047 (/NAS)
Determination of adult lifespan GO:0008340
The control of viability and duration in the adult phase of the life-cycle.
2 P91283 (/IMP) Q7JNG1 (/IMP)
ATP metabolic process GO:0046034
The chemical reactions and pathways involving ATP, adenosine triphosphate, a universally important coenzyme and enzyme regulator.
2 Q9DB20 (/ISO) Q9DB20 (/ISO)
Mitochondrial ATP synthesis coupled proton transport GO:0042776
The transport of protons across a mitochondrial membrane to generate an electrochemical gradient (proton-motive force) that powers ATP synthesis.
1 Q24439 (/ISS)
ATP metabolic process GO:0046034
The chemical reactions and pathways involving ATP, adenosine triphosphate, a universally important coenzyme and enzyme regulator.
1 Q06647 (/IDA)
Cellular response to cAMP GO:0071320
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cAMP (cyclic AMP, adenosine 3',5'-cyclophosphate) stimulus.
1 Q06647 (/IEP)
Cellular response to cytokine stimulus GO:0071345
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cytokine stimulus.
1 Q06647 (/IEP)
Proton transmembrane transport GO:1902600
The directed movement of a proton across a membrane.
1 Q24439 (/ISS)

There are 23 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
15 P09457 (/HDA) P09457 (/HDA) P09457 (/HDA) P09457 (/HDA) P09457 (/HDA) P09457 (/HDA) P09457 (/HDA) P09457 (/HDA) P09457 (/HDA) P48047 (/HDA)
(5 more)
Mitochondrial proton-transporting ATP synthase, stator stalk GO:0000274
One of two stalks that connect the catalytic core of the hydrogen-transporting ATP synthase to the mitochondrial membrane-associated F0 proteins; is thought to prevent futile rotation of the catalytic core.
9 P09457 (/IDA) P09457 (/IDA) P09457 (/IDA) P09457 (/IDA) P09457 (/IDA) P09457 (/IDA) P09457 (/IDA) P09457 (/IDA) P09457 (/IDA)
Mitochondrial proton-transporting ATP synthase, stator stalk GO:0000274
One of two stalks that connect the catalytic core of the hydrogen-transporting ATP synthase to the mitochondrial membrane-associated F0 proteins; is thought to prevent futile rotation of the catalytic core.
9 P09457 (/IMP) P09457 (/IMP) P09457 (/IMP) P09457 (/IMP) P09457 (/IMP) P09457 (/IMP) P09457 (/IMP) P09457 (/IMP) P09457 (/IMP)
Mitochondrial proton-transporting ATP synthase complex GO:0005753
A proton-transporting ATP synthase complex found in the mitochondrial membrane.
9 B0VXH3 (/ISS) B1MT69 (/ISS) B2B9A1 (/ISS) B3EX21 (/ISS) Q2EN81 (/ISS) Q2EN81 (/ISS) Q5RD23 (/ISS) Q9DB20 (/ISS) Q9DB20 (/ISS)
Mitochondrial proton-transporting ATP synthase complex GO:0005753
A proton-transporting ATP synthase complex found in the mitochondrial membrane.
6 P13621 (/IDA) P48047 (/IDA) P48047 (/IDA) P48047 (/IDA) Q06647 (/IDA) Q96251 (/IDA)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
5 P48047 (/IDA) P48047 (/IDA) P48047 (/IDA) Q06647 (/IDA) Q96251 (/IDA)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
5 P48047 (/IDA) P48047 (/IDA) P48047 (/IDA) Q06647 (/IDA) Q96251 (/IDA)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
3 P48047 (/HDA) P48047 (/HDA) P48047 (/HDA)
Mitochondrial inner membrane GO:0005743
The inner, i.e. lumen-facing, lipid bilayer of the mitochondrial envelope. It is highly folded to form cristae.
3 P48047 (/TAS) P48047 (/TAS) P48047 (/TAS)
Mitochondrial proton-transporting ATP synthase complex GO:0005753
A proton-transporting ATP synthase complex found in the mitochondrial membrane.
3 P48047 (/NAS) P48047 (/NAS) P48047 (/NAS)
Mitochondrial proton-transporting ATP synthase complex, coupling factor F(o) GO:0000276
All non-F1 subunits of the mitochondrial hydrogen-transporting ATP synthase, including integral and peripheral mitochondrial inner membrane proteins.
2 Q9DB20 (/ISO) Q9DB20 (/ISO)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
2 Q9DB20 (/ISO) Q9DB20 (/ISO)
Mitochondrial proton-transporting ATP synthase complex GO:0005753
A proton-transporting ATP synthase complex found in the mitochondrial membrane.
2 Q9DB20 (/ISO) Q9DB20 (/ISO)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
2 Q9DB20 (/ISO) Q9DB20 (/ISO)
Cell surface GO:0009986
The external part of the cell wall and/or plasma membrane.
2 Q9DB20 (/ISO) Q9DB20 (/ISO)
Myelin sheath GO:0043209
An electrically insulating fatty layer that surrounds the axons of many neurons. It is an outgrowth of glial cells: Schwann cells supply the myelin for peripheral neurons while oligodendrocytes supply it to those of the central nervous system.
2 Q9DB20 (/HDA) Q9DB20 (/HDA)
Mitochondrial proton-transporting ATP synthase, stator stalk GO:0000274
One of two stalks that connect the catalytic core of the hydrogen-transporting ATP synthase to the mitochondrial membrane-associated F0 proteins; is thought to prevent futile rotation of the catalytic core.
1 O74479 (/ISO)
Mitochondrial proton-transporting ATP synthase complex, coupling factor F(o) GO:0000276
All non-F1 subunits of the mitochondrial hydrogen-transporting ATP synthase, including integral and peripheral mitochondrial inner membrane proteins.
1 Q06647 (/IDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
1 O74479 (/HDA)
Mitochondrial proton-transporting ATP synthase, central stalk GO:0005756
One of two stalks that connect the catalytic core of the hydrogen-transporting ATP synthase to the mitochondrial membrane-associated F0 proteins; rotates within the catalytic core during catalysis.
1 Q24439 (/ISS)
Chloroplast GO:0009507
A chlorophyll-containing plastid with thylakoids organized into grana and frets, or stroma thylakoids, and embedded in a stroma.
1 Q96251 (/IDA)
Cell surface GO:0009986
The external part of the cell wall and/or plasma membrane.
1 Q06647 (/IDA)
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
1 Q96251 (/IDA)
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