The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:
"Transferase(Phosphotransferase) domain 1
".
FunFam 24: Probable serine/threonine-protein kinase cot-1
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 20 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
9 | O13310 (/IPI) O95835 (/IPI) P53894 (/IPI) P53894 (/IPI) Q5B1Q1 (/IPI) Q5B1Q1 (/IPI) Q9NRM7 (/IPI) Q9NRM7 (/IPI) Q9VA38 (/IPI) |
Protein serine/threonine kinase activity GO:0004674
Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate.
|
7 | O13310 (/IDA) O95835 (/IDA) P53894 (/IDA) P53894 (/IDA) Q9NRM7 (/IDA) Q9NRM7 (/IDA) Q9VA38 (/IDA) |
Protein serine/threonine kinase activity GO:0004674
Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate.
|
4 | Q54IH8 (/ISS) Q7TSJ6 (/ISS) Q8BYR2 (/ISS) Q9VA38 (/ISS) |
Protein serine/threonine kinase activity GO:0004674
Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate.
|
4 | O95835 (/TAS) Q9NRM7 (/TAS) Q9NRM7 (/TAS) Q9VA38 (/TAS) |
ATP binding GO:0005524
Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
|
3 | O95835 (/IDA) Q9NRM7 (/IDA) Q9NRM7 (/IDA) |
Protein serine/threonine kinase activity GO:0004674
Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate.
|
2 | Q7TSJ6 (/ISO) Q8BYR2 (/ISO) |
ATP binding GO:0005524
Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
|
2 | Q7TSJ6 (/ISO) Q8BYR2 (/ISO) |
ATP binding GO:0005524
Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
|
2 | Q7TSJ6 (/ISS) Q8BYR2 (/ISS) |
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
|
2 | P53894 (/IPI) P53894 (/IPI) |
Magnesium ion binding GO:0000287
Interacting selectively and non-covalently with magnesium (Mg) ions.
|
1 | O95835 (/IDA) |
Showing 1 to 10 of 20 entries
There are 119 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Hippo signaling GO:0035329
The series of molecular signals mediated by the serine/threonine kinase Hippo or one of its orthologs. In Drosophila, Hippo in complex with the scaffold protein Salvador (Sav), phosphorylates and activates Warts (Wts), which in turn phosphorylates and inactivates the Yorkie (Yki) transcriptional activator. The core fly components hippo, sav, wts and mats are conserved in mammals as STK4/3 (MST1/2), SAV1/WW45, LATS1/2 and MOB1.
|
11 |
A0A2R8QB11 (/TAS)
A0A2R8QF71 (/TAS)
B0S8I4 (/TAS)
B2BJC0 (/TAS)
B2BJC1 (/TAS)
F1QGL3 (/TAS)
O95835 (/TAS)
Q58FB8 (/TAS)
Q5RIL6 (/TAS)
Q9NRM7 (/TAS)
(1 more) |
Secondary heart field specification GO:0003139
The process that results in the delineation of a specific region of the lateral mesoderm into the area which will form the majority of the mesodermal component of the right ventricle, arterial pole (outflow tract) and venous pole (inflow tract).
|
8 | A0A2R8QB11 (/IGI) A0A2R8QF71 (/IGI) B0S8I4 (/IGI) B2BJC0 (/IGI) B2BJC1 (/IGI) F1QGL3 (/IGI) Q58FB8 (/IGI) Q5RIL6 (/IGI) |
Secondary heart field specification GO:0003139
The process that results in the delineation of a specific region of the lateral mesoderm into the area which will form the majority of the mesodermal component of the right ventricle, arterial pole (outflow tract) and venous pole (inflow tract).
|
8 | A0A2R8QB11 (/IMP) A0A2R8QF71 (/IMP) B0S8I4 (/IMP) B2BJC0 (/IMP) B2BJC1 (/IMP) F1QGL3 (/IMP) Q58FB8 (/IMP) Q5RIL6 (/IMP) |
BMP signaling pathway GO:0030509
A series of molecular signals initiated by the binding of a member of the BMP (bone morphogenetic protein) family to a receptor on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription.
|
8 | A0A2R8QB11 (/IGI) A0A2R8QF71 (/IGI) B0S8I4 (/IGI) B2BJC0 (/IGI) B2BJC1 (/IGI) F1QGL3 (/IGI) Q58FB8 (/IGI) Q5RIL6 (/IGI) |
BMP signaling pathway GO:0030509
A series of molecular signals initiated by the binding of a member of the BMP (bone morphogenetic protein) family to a receptor on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription.
|
8 | A0A2R8QB11 (/IMP) A0A2R8QF71 (/IMP) B0S8I4 (/IMP) B2BJC0 (/IMP) B2BJC1 (/IMP) F1QGL3 (/IMP) Q58FB8 (/IMP) Q5RIL6 (/IMP) |
Convergent extension involved in gastrulation GO:0060027
The morphogenetic process in which an epithelium narrows along one axis and lengthens in a perpendicular axis usually resulting in the formation of the three primary germ layers, ectoderm, mesoderm and endoderm.
|
8 | A0A2R8QB11 (/IGI) A0A2R8QF71 (/IGI) B0S8I4 (/IGI) B2BJC0 (/IGI) B2BJC1 (/IGI) F1QGL3 (/IGI) Q58FB8 (/IGI) Q5RIL6 (/IGI) |
Convergent extension involved in gastrulation GO:0060027
The morphogenetic process in which an epithelium narrows along one axis and lengthens in a perpendicular axis usually resulting in the formation of the three primary germ layers, ectoderm, mesoderm and endoderm.
|
8 | A0A2R8QB11 (/IMP) A0A2R8QF71 (/IMP) B0S8I4 (/IMP) B2BJC0 (/IMP) B2BJC1 (/IMP) F1QGL3 (/IMP) Q58FB8 (/IMP) Q5RIL6 (/IMP) |
Protein phosphorylation GO:0006468
The process of introducing a phosphate group on to a protein.
|
6 | O95835 (/IDA) P53894 (/IDA) P53894 (/IDA) Q7TSJ6 (/IDA) Q9NRM7 (/IDA) Q9NRM7 (/IDA) |
Establishment or maintenance of cell polarity GO:0007163
Any cellular process that results in the specification, formation or maintenance of anisotropic intracellular organization or cell growth patterns.
|
5 | P53894 (/IMP) P53894 (/IMP) Q5AP53 (/IMP) Q5B1Q1 (/IMP) Q5B1Q1 (/IMP) |
Hippo signaling GO:0035329
The series of molecular signals mediated by the serine/threonine kinase Hippo or one of its orthologs. In Drosophila, Hippo in complex with the scaffold protein Salvador (Sav), phosphorylates and activates Warts (Wts), which in turn phosphorylates and inactivates the Yorkie (Yki) transcriptional activator. The core fly components hippo, sav, wts and mats are conserved in mammals as STK4/3 (MST1/2), SAV1/WW45, LATS1/2 and MOB1.
|
4 | O95835 (/IDA) Q9NRM7 (/IDA) Q9NRM7 (/IDA) Q9VA38 (/IDA) |
Showing 1 to 10 of 119 entries
There are 38 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
7 | A0A024RDM3 (/IDA) A0A024RDM3 (/IDA) Q5B1Q1 (/IDA) Q5B1Q1 (/IDA) Q9NRM7 (/IDA) Q9NRM7 (/IDA) Q9VA38 (/IDA) |
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
5 | O45797 (/IDA) P53894 (/IDA) P53894 (/IDA) Q5B1Q1 (/IDA) Q5B1Q1 (/IDA) |
Spindle pole GO:0000922
Either of the ends of a spindle, where spindle microtubules are organized; usually contains a microtubule organizing center and accessory molecules, spindle microtubules and astral microtubules.
|
4 | O95835 (/IDA) Q7TSJ6 (/IDA) Q9NRM7 (/IDA) Q9NRM7 (/IDA) |
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
4 | P53894 (/IDA) P53894 (/IDA) Q9NRM7 (/IDA) Q9NRM7 (/IDA) |
Microtubule organizing center GO:0005815
An intracellular structure that can catalyze gamma-tubulin-dependent microtubule nucleation and that can anchor microtubules by interacting with their minus ends, plus ends or sides.
|
4 | A0A024RDM3 (/IDA) A0A024RDM3 (/IDA) Q9NRM7 (/IDA) Q9NRM7 (/IDA) |
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
4 | O95835 (/TAS) Q9NRM7 (/TAS) Q9NRM7 (/TAS) Q9VA38 (/TAS) |
Hyphal tip GO:0001411
The end, or tip, of a fungal hypha, where polarized growth occurs during hyphal elongation.
|
3 | Q5AP53 (/IDA) Q5B1Q1 (/IDA) Q5B1Q1 (/IDA) |
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
3 | O45797 (/IDA) P38679 (/IDA) P38679 (/IDA) |
Cellular bud neck GO:0005935
The constriction between the mother cell and daughter cell (bud) in an organism that reproduces by budding.
|
3 | P53894 (/IDA) P53894 (/IDA) Q5AP53 (/IDA) |
Cell cortex GO:0005938
The region of a cell that lies just beneath the plasma membrane and often, but not always, contains a network of actin filaments and associated proteins.
|
3 | P53894 (/IDA) P53894 (/IDA) Q5AP53 (/IDA) |
Showing 1 to 10 of 38 entries