The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:

"
Transferase(Phosphotransferase) domain 1
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 217: Wee1-like protein kinase

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 6 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
5 P30291 (/IPI) P47810 (/IPI) P54350 (/IPI) P54350 (/IPI) Q8QGV2 (/IPI)
Protein tyrosine kinase activity GO:0004713
Catalysis of the reaction: ATP + a protein tyrosine = ADP + protein tyrosine phosphate.
4 A4PES0 (/TAS) A4PES0 (/TAS) P30291 (/TAS) Q66JT0 (/TAS)
Protein tyrosine kinase activity GO:0004713
Catalysis of the reaction: ATP + a protein tyrosine = ADP + protein tyrosine phosphate.
3 P47817 (/IDA) P54350 (/IDA) P54350 (/IDA)
Protein kinase activity GO:0004672
Catalysis of the phosphorylation of an amino acid residue in a protein, usually according to the reaction: a protein + ATP = a phosphoprotein + ADP.
1 P47810 (/IDA)
Kinase activity GO:0016301
Catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule.
1 P30291 (/TAS)
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
1 Q8QGV2 (/IPI)

There are 36 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Response to light stimulus GO:0009416
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a light stimulus, electromagnetic radiation of wavelengths classified as infrared, visible or ultraviolet light.
5 A0A2R8QB38 (/IDA) Q1JPW8 (/IDA) Q1LYE1 (/IDA) Q6DRI0 (/IDA) Q6PEG5 (/IDA)
Positive regulation of phosphorylation GO:0042327
Any process that activates or increases the frequency, rate or extent of addition of phosphate groups to a molecule.
4 A4PES0 (/ISS) A4PES0 (/ISS) D2HHP1 (/ISS) E2RSS3 (/ISS)
Regulation of fertilization GO:0080154
Any process that modulates the rate, frequency or extent of fertilization. Fertilization is the union of gametes of opposite sexes during the process of sexual reproduction to form a zygote. It involves the fusion of the gametic nuclei (karyogamy) and cytoplasm (plasmogamy).
4 A4PES0 (/ISS) A4PES0 (/ISS) D2HHP1 (/ISS) E2RSS3 (/ISS)
Protein phosphorylation GO:0006468
The process of introducing a phosphate group on to a protein.
3 P47810 (/IDA) P54350 (/IDA) P54350 (/IDA)
Female meiotic nuclear division GO:0007143
A cell cycle process by which the cell nucleus divides as part of a meiotic cell cycle in the female germline.
3 D2HHP1 (/ISS) E2RSS3 (/ISS) P0C1S8 (/ISS)
Female pronucleus assembly GO:0035038
Assembly of the haploid nucleus of the unfertilized egg.
3 D2HHP1 (/ISS) E2RSS3 (/ISS) P0C1S8 (/ISS)
Negative regulation of cyclin-dependent protein serine/threonine kinase activity GO:0045736
Any process that stops, prevents, or reduces the frequency, rate or extent of cyclin-dependent protein serine/threonine kinase activity.
3 P54350 (/IMP) P54350 (/IMP) Q66JT0 (/IMP)
Regulation of meiosis I GO:0060631
Any process that modulates the rate, frequency, or extent of meiosis I, a cell cycle process comprising the steps by which a cell progresses through the first phase of meiosis, in which cells divide and homologous chromosomes are paired and segregated from each other, producing two daughter cells.
3 D2HHP1 (/ISS) E2RSS3 (/ISS) P0C1S8 (/ISS)
Negative regulation of oocyte maturation GO:1900194
Any process that stops, prevents or reduces the frequency, rate or extent of oocyte maturation.
3 D2HHP1 (/ISS) E2RSS3 (/ISS) P0C1S8 (/ISS)
Embryonic development via the syncytial blastoderm GO:0001700
The process whose specific outcome is the progression of the embryo over time, from zygote formation through syncytial blastoderm to the hatching of the first instar larva. An example of this process is found in Drosophila melanogaster.
2 P54350 (/TAS) P54350 (/TAS)
Mitotic cell cycle checkpoint GO:0007093
A cell cycle checkpoint that ensures accurate chromosome replication and segregation by preventing progression through a mitotic cell cycle until conditions are suitable for the cell to proceed to the next stage.
2 P54350 (/IDA) P54350 (/IDA)
Female meiotic nuclear division GO:0007143
A cell cycle process by which the cell nucleus divides as part of a meiotic cell cycle in the female germline.
2 A4PES0 (/IDA) A4PES0 (/IDA)
Peptidyl-tyrosine phosphorylation GO:0018108
The phosphorylation of peptidyl-tyrosine to form peptidyl-O4'-phospho-L-tyrosine.
2 P47810 (/IDA) P47817 (/IDA)
Peptidyl-tyrosine phosphorylation GO:0018108
The phosphorylation of peptidyl-tyrosine to form peptidyl-O4'-phospho-L-tyrosine.
2 P54350 (/IMP) P54350 (/IMP)
Negative regulation of cyclin-dependent protein serine/threonine kinase activity GO:0045736
Any process that stops, prevents, or reduces the frequency, rate or extent of cyclin-dependent protein serine/threonine kinase activity.
2 P54350 (/IDA) P54350 (/IDA)
Spindle assembly GO:0051225
The aggregation, arrangement and bonding together of a set of components to form the spindle, the array of microtubules and associated molecules that serves to move duplicated chromosomes apart.
2 P54350 (/IMP) P54350 (/IMP)
Centrosome separation GO:0051299
The process in which duplicated centrosome components move away from each other. The centriole pair within each centrosome becomes part of a separate microtubule organizing center that nucleates a radial array of microtubules called an aster. The two asters move to opposite sides of the nucleus to form the two poles of the mitotic spindle.
2 P54350 (/IMP) P54350 (/IMP)
Centrosome localization GO:0051642
Any process in which a centrosome is transported to, and/or maintained in, a specific location within the cell.
2 P54350 (/IMP) P54350 (/IMP)
Negative regulation of oocyte development GO:0060283
Any process that decreases the rate or extent of the process whose specific outcome is the progression of an oocyte over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell.
2 A4PES0 (/IDA) A4PES0 (/IDA)
Regulation of meiosis I GO:0060631
Any process that modulates the rate, frequency, or extent of meiosis I, a cell cycle process comprising the steps by which a cell progresses through the first phase of meiosis, in which cells divide and homologous chromosomes are paired and segregated from each other, producing two daughter cells.
2 A4PES0 (/IDA) A4PES0 (/IDA)
Negative regulation of meiotic cell cycle process involved in oocyte maturation GO:1904145
Any process that stops, prevents or reduces the frequency, rate or extent of meiotic cell cycle process involved in oocyte maturation.
2 A4PES0 (/IMP) A4PES0 (/IMP)
G2/M transition of mitotic cell cycle GO:0000086
The mitotic cell cycle transition by which a cell in G2 commits to M phase. The process begins when the kinase activity of M cyclin/CDK complex reaches a threshold high enough for the cell cycle to proceed. This is accomplished by activating a positive feedback loop that results in the accumulation of unphosphorylated and active M cyclin/CDK complex.
1 P30291 (/TAS)
Microtubule cytoskeleton organization GO:0000226
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising microtubules and their associated proteins.
1 P47810 (/IMP)
Regulation of mitotic nuclear division GO:0007088
Any process that modulates the frequency, rate or extent of mitosis.
1 P47817 (/IMP)
Female meiotic nuclear division GO:0007143
A cell cycle process by which the cell nucleus divides as part of a meiotic cell cycle in the female germline.
1 Q66JT0 (/IMP)
Establishment of cell polarity GO:0030010
The specification and formation of anisotropic intracellular organization or cell growth patterns.
1 P47810 (/IMP)
Mitotic DNA replication checkpoint GO:0033314
A cell cycle checkpoint that acts during a mitotic cell cycle and prevents the initiation of mitosis until DNA replication is complete, thereby ensuring that progeny inherit a full complement of the genome.
1 P47817 (/IMP)
Female pronucleus assembly GO:0035038
Assembly of the haploid nucleus of the unfertilized egg.
1 Q66JT0 (/IMP)
Positive regulation of phosphorylation GO:0042327
Any process that activates or increases the frequency, rate or extent of addition of phosphate groups to a molecule.
1 Q66JT0 (/IDA)
Negative regulation of cell cycle GO:0045786
Any process that stops, prevents or reduces the rate or extent of progression through the cell cycle.
1 Q8QGV2 (/IDA)
Neuron projection morphogenesis GO:0048812
The process in which the anatomical structures of a neuron projection are generated and organized. A neuron projection is any process extending from a neural cell, such as axons or dendrites.
1 P47810 (/IGI)
Neuron projection morphogenesis GO:0048812
The process in which the anatomical structures of a neuron projection are generated and organized. A neuron projection is any process extending from a neural cell, such as axons or dendrites.
1 P47810 (/IMP)
Regulation of meiosis I GO:0060631
Any process that modulates the rate, frequency, or extent of meiosis I, a cell cycle process comprising the steps by which a cell progresses through the first phase of meiosis, in which cells divide and homologous chromosomes are paired and segregated from each other, producing two daughter cells.
1 Q66JT0 (/IMP)
Regulation of fertilization GO:0080154
Any process that modulates the rate, frequency or extent of fertilization. Fertilization is the union of gametes of opposite sexes during the process of sexual reproduction to form a zygote. It involves the fusion of the gametic nuclei (karyogamy) and cytoplasm (plasmogamy).
1 Q66JT0 (/IMP)
Negative regulation of oocyte maturation GO:1900194
Any process that stops, prevents or reduces the frequency, rate or extent of oocyte maturation.
1 Q66JT0 (/IMP)
Negative regulation of G1/S transition of mitotic cell cycle GO:2000134
Any signalling pathway that decreases or inhibits the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G1 phase to S phase of the mitotic cell cycle.
1 P30291 (/TAS)

There are 12 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
6 A4PES0 (/IDA) A4PES0 (/IDA) P47817 (/IDA) P54350 (/IDA) P54350 (/IDA) Q66JT0 (/IDA)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
2 D2HHP1 (/ISS) E2RSS3 (/ISS)
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
2 P30291 (/TAS) P47810 (/TAS)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
2 P47810 (/IDA) Q66JT0 (/IDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
2 D2HHP1 (/ISS) E2RSS3 (/ISS)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
2 P0C1S8 (/IDA) P47817 (/IDA)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
1 P30291 (/TAS)
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
1 P0C1S8 (/IDA)
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
1 Q66JT0 (/ISO)
Nucleolus GO:0005730
A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome.
1 P30291 (/IDA)
Nucleolus GO:0005730
A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome.
1 P47810 (/ISO)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
1 Q66JT0 (/ISO)
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