The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:
"GTPase Activation - p120gap; domain 1
".
FunFam 10: Plexin B1
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 18 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
4 | O43157 (/IPI) Q8CJH3 (/IPI) Q9QY40 (/IPI) Q9ULL4 (/IPI) |
Semaphorin receptor activity GO:0017154
Combining with a semaphorin, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
|
3 | D3ZLH5 (/ISS) Q8CJH3 (/ISS) Q9QY40 (/ISS) |
Semaphorin receptor activity GO:0017154
Combining with a semaphorin, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
|
2 | O43157 (/IDA) Q9ULL4 (/IDA) |
Semaphorin receptor activity GO:0017154
Combining with a semaphorin, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
|
2 | Q8CJH3 (/ISO) Q9QY40 (/ISO) |
Protein domain specific binding GO:0019904
Interacting selectively and non-covalently with a specific domain of a protein.
|
2 | D3ZLH5 (/ISS) Q9QY40 (/ISS) |
Transmembrane signaling receptor activity GO:0004888
Combining with an extracellular or intracellular signal and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity or state as part of signal transduction.
|
1 | O43157 (/NAS) |
GTPase activator activity GO:0005096
Binds to and increases the activity of a GTPase, an enzyme that catalyzes the hydrolysis of GTP.
|
1 | O43157 (/TAS) |
Semaphorin receptor activity GO:0017154
Combining with a semaphorin, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
|
1 | Q8CJH3 (/IMP) |
Semaphorin receptor activity GO:0017154
Combining with a semaphorin, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
|
1 | O43157 (/TAS) |
Protein domain specific binding GO:0019904
Interacting selectively and non-covalently with a specific domain of a protein.
|
1 | Q9ULL4 (/IPI) |
Showing 1 to 10 of 18 entries
There are 55 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Negative regulation of cell adhesion GO:0007162
Any process that stops, prevents, or reduces the frequency, rate or extent of cell adhesion.
|
3 | D3ZLH5 (/ISS) Q8CJH3 (/ISS) Q9QY40 (/ISS) |
Negative regulation of cell adhesion GO:0007162
Any process that stops, prevents, or reduces the frequency, rate or extent of cell adhesion.
|
2 | O43157 (/IDA) Q9ULL4 (/IDA) |
Negative regulation of cell adhesion GO:0007162
Any process that stops, prevents, or reduces the frequency, rate or extent of cell adhesion.
|
2 | Q8CJH3 (/ISO) Q9QY40 (/ISO) |
Negative regulation of lamellipodium assembly GO:0010593
Any process that decreases the rate, frequency or extent of the formation of a lamellipodium, a thin sheetlike extension of the surface of a migrating cell.
|
2 | Q9QY40 (/ISS) Q9ULL4 (/ISS) |
Negative regulation of cell migration GO:0030336
Any process that stops, prevents, or reduces the frequency, rate or extent of cell migration.
|
2 | D3ZLH5 (/IMP) Q9ULL4 (/IMP) |
Negative regulation of GTPase activity GO:0034260
Any process that stops or reduces the rate of GTP hydrolysis by a GTPase.
|
2 | D3ZLH5 (/ISS) Q9QY40 (/ISS) |
Positive chemotaxis GO:0050918
The directed movement of a motile cell or organism towards a higher concentration of a chemical.
|
2 | D3ZLH5 (/ISS) Q9QY40 (/ISS) |
Semaphorin-plexin signaling pathway GO:0071526
A series of molecular signals generated as a consequence of a semaphorin receptor (composed of a plexin and a neurophilin) binding to a semaphorin ligand.
|
2 | O43157 (/IDA) Q9ULL4 (/IDA) |
Semaphorin-plexin signaling pathway GO:0071526
A series of molecular signals generated as a consequence of a semaphorin receptor (composed of a plexin and a neurophilin) binding to a semaphorin ligand.
|
2 | D3ZLH5 (/IMP) Q8CJH3 (/IMP) |
Semaphorin-plexin signaling pathway GO:0071526
A series of molecular signals generated as a consequence of a semaphorin receptor (composed of a plexin and a neurophilin) binding to a semaphorin ligand.
|
2 | Q8CJH3 (/ISO) Q9QY40 (/ISO) |
Showing 1 to 10 of 55 entries
There are 12 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
2 | O43157 (/TAS) Q9ULL4 (/TAS) |
Semaphorin receptor complex GO:0002116
A stable binary complex of a neurophilin and a plexin, together forming a functional semaphorin receptor.
|
1 | O43157 (/IDA) |
Semaphorin receptor complex GO:0002116
A stable binary complex of a neurophilin and a plexin, together forming a functional semaphorin receptor.
|
1 | Q8CJH3 (/ISO) |
Semaphorin receptor complex GO:0002116
A stable binary complex of a neurophilin and a plexin, together forming a functional semaphorin receptor.
|
1 | Q8CJH3 (/ISS) |
Semaphorin receptor complex GO:0002116
A stable binary complex of a neurophilin and a plexin, together forming a functional semaphorin receptor.
|
1 | O43157 (/TAS) |
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
|
1 | O43157 (/IDA) |
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
|
1 | Q8CJH3 (/ISO) |
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
|
1 | Q8CJH3 (/ISS) |
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
|
1 | O43157 (/NAS) |
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
|
1 | O43157 (/TAS) |
Showing 1 to 10 of 12 entries