The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:

"
Phosphomannose Isomerase, domain 2
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 2: Mannose-6-phosphate isomerase

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 4 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Mannose-6-phosphate isomerase activity GO:0004476
Catalysis of the reaction: D-mannose 6-phosphate = D-fructose 6-phosphate.
20 A0A2R8QRD7 (/IDA) P00946 (/IDA) P00946 (/IDA) P00946 (/IDA) P00946 (/IDA) P00946 (/IDA) P00946 (/IDA) P00946 (/IDA) P00946 (/IDA) P00946 (/IDA)
(10 more)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
19 P00946 (/IPI) P00946 (/IPI) P00946 (/IPI) P00946 (/IPI) P00946 (/IPI) P00946 (/IPI) P00946 (/IPI) P00946 (/IPI) P00946 (/IPI) P00946 (/IPI)
(9 more)
Mannose-6-phosphate isomerase activity GO:0004476
Catalysis of the reaction: D-mannose 6-phosphate = D-fructose 6-phosphate.
9 Q9KR20 (/ISS) Q9KR20 (/ISS) Q9KR20 (/ISS) Q9KR20 (/ISS) Q9KV87 (/ISS) Q9KV87 (/ISS) Q9KV87 (/ISS) Q9KV87 (/ISS) Q9KV87 (/ISS)
Mannose-6-phosphate isomerase activity GO:0004476
Catalysis of the reaction: D-mannose 6-phosphate = D-fructose 6-phosphate.
1 A0A2R8QRD7 (/IMP)

There are 7 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Colanic acid biosynthetic process GO:0009242
The chemical reactions and pathways resulting in the formation of colanic acid, a capsular bacterial polysaccharide.
19 P00946 (/IMP) P00946 (/IMP) P00946 (/IMP) P00946 (/IMP) P00946 (/IMP) P00946 (/IMP) P00946 (/IMP) P00946 (/IMP) P00946 (/IMP) P00946 (/IMP)
(9 more)
GDP-mannose biosynthetic process GO:0009298
The chemical reactions and pathways resulting in the formation of GDP-mannose, a substance composed of mannose in glycosidic linkage with guanosine diphosphate.
19 P00946 (/IMP) P00946 (/IMP) P00946 (/IMP) P00946 (/IMP) P00946 (/IMP) P00946 (/IMP) P00946 (/IMP) P00946 (/IMP) P00946 (/IMP) P00946 (/IMP)
(9 more)
Mannose catabolic process GO:0019309
The chemical reactions and pathways resulting in the breakdown of mannose, the aldohexose manno-hexose, the C-2 epimer of glucose.
19 P00946 (/IMP) P00946 (/IMP) P00946 (/IMP) P00946 (/IMP) P00946 (/IMP) P00946 (/IMP) P00946 (/IMP) P00946 (/IMP) P00946 (/IMP) P00946 (/IMP)
(9 more)
Carbohydrate metabolic process GO:0005975
The chemical reactions and pathways involving carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y. Includes the formation of carbohydrate derivatives by the addition of a carbohydrate residue to another molecule.
9 Q9KR20 (/ISS) Q9KR20 (/ISS) Q9KR20 (/ISS) Q9KR20 (/ISS) Q9KV87 (/ISS) Q9KV87 (/ISS) Q9KV87 (/ISS) Q9KV87 (/ISS) Q9KV87 (/ISS)
Liver development GO:0001889
The process whose specific outcome is the progression of the liver over time, from its formation to the mature structure. The liver is an exocrine gland which secretes bile and functions in metabolism of protein and carbohydrate and fat, synthesizes substances involved in the clotting of the blood, synthesizes vitamin A, detoxifies poisonous substances, stores glycogen, and breaks down worn-out erythrocytes.
1 A0A2R8QRD7 (/IMP)
Chordate embryonic development GO:0043009
The process whose specific outcome is the progression of the embryo over time, from zygote formation through a stage including a notochord and neural tube until birth or egg hatching.
1 A0A2R8QRD7 (/IMP)
Chondrocyte morphogenesis GO:0090171
The process in which the structures of a chondrocyte are generated and organized. This process occurs while the initially relatively unspecialized cell is acquiring the specialized features of a chondrocyte.
1 A0A2R8QRD7 (/IGI)

There are 3 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
19 P00946 (/IDA) P00946 (/IDA) P00946 (/IDA) P00946 (/IDA) P00946 (/IDA) P00946 (/IDA) P00946 (/IDA) P00946 (/IDA) P00946 (/IDA) P00946 (/IDA)
(9 more)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
9 O05898 (/HDA) O05898 (/HDA) O05898 (/HDA) O05898 (/HDA) O05898 (/HDA) O05898 (/HDA) O05898 (/HDA) O05898 (/HDA) O05898 (/HDA)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
9 O05898 (/HDA) O05898 (/HDA) O05898 (/HDA) O05898 (/HDA) O05898 (/HDA) O05898 (/HDA) O05898 (/HDA) O05898 (/HDA) O05898 (/HDA)
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