The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:

"
Phosphomannose Isomerase, domain 2
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 1: Mannose-6-phosphate isomerase

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 5 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Mannose-6-phosphate isomerase activity GO:0004476
Catalysis of the reaction: D-mannose 6-phosphate = D-fructose 6-phosphate.
16 P29952 (/IDA) P29952 (/IDA) P29952 (/IDA) P29952 (/IDA) P29952 (/IDA) P34948 (/IDA) P34948 (/IDA) Q3ZB95 (/IDA) Q66WM4 (/IDA) Q66WM4 (/IDA)
(6 more)
Mannose-6-phosphate isomerase activity GO:0004476
Catalysis of the reaction: D-mannose 6-phosphate = D-fructose 6-phosphate.
3 Q3ZB95 (/IMP) Q924M7 (/IMP) Q924M7 (/IMP)
Mannose-6-phosphate isomerase activity GO:0004476
Catalysis of the reaction: D-mannose 6-phosphate = D-fructose 6-phosphate.
2 P34948 (/IGI) P34948 (/IGI)
Mannose-6-phosphate isomerase activity GO:0004476
Catalysis of the reaction: D-mannose 6-phosphate = D-fructose 6-phosphate.
2 P34949 (/TAS) P34949 (/TAS)
Mannose-6-phosphate isomerase activity GO:0004476
Catalysis of the reaction: D-mannose 6-phosphate = D-fructose 6-phosphate.
1 Q54PA0 (/ISS)

There are 23 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
GDP-mannose biosynthetic process GO:0009298
The chemical reactions and pathways resulting in the formation of GDP-mannose, a substance composed of mannose in glycosidic linkage with guanosine diphosphate.
7 P29952 (/IMP) P29952 (/IMP) P29952 (/IMP) P29952 (/IMP) P29952 (/IMP) Q924M7 (/IMP) Q924M7 (/IMP)
Cell wall mannoprotein biosynthetic process GO:0000032
The chemical reactions and pathways resulting in the formation of cell wall mannoproteins, any cell wall protein that contains covalently bound mannose residues.
5 P29952 (/IMP) P29952 (/IMP) P29952 (/IMP) P29952 (/IMP) P29952 (/IMP)
Protein glycosylation GO:0006486
A protein modification process that results in the addition of a carbohydrate or carbohydrate derivative unit to a protein amino acid, e.g. the addition of glycan chains to proteins.
5 P29952 (/IMP) P29952 (/IMP) P29952 (/IMP) P29952 (/IMP) P29952 (/IMP)
Mannose metabolic process GO:0006013
The chemical reactions and pathways involving mannose, the aldohexose manno-hexose, the C-2 epimer of glucose. The D-(+)-form is widely distributed in mannans and hemicelluloses and is of major importance in the core oligosaccharide of N-linked oligosaccharides of glycoproteins.
3 Q66WM4 (/IMP) Q66WM4 (/IMP) Q66WM4 (/IMP)
Response to zinc ion GO:0010043
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a zinc ion stimulus.
3 Q9FZH5 (/IEP) Q9M884 (/IEP) Q9M884 (/IEP)
Response to L-ascorbic acid GO:0033591
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an L-ascorbic acid (vitamin C) stimulus.
3 Q9FZH5 (/IEP) Q9M884 (/IEP) Q9M884 (/IEP)
Response to cadmium ion GO:0046686
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cadmium (Cd) ion stimulus.
3 Q9FZH5 (/IEP) Q9M884 (/IEP) Q9M884 (/IEP)
GDP-mannose biosynthetic process GO:0009298
The chemical reactions and pathways resulting in the formation of GDP-mannose, a substance composed of mannose in glycosidic linkage with guanosine diphosphate.
2 P34949 (/TAS) P34949 (/TAS)
Response to light stimulus GO:0009416
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a light stimulus, electromagnetic radiation of wavelengths classified as infrared, visible or ultraviolet light.
2 Q9M884 (/IEP) Q9M884 (/IEP)
Embryo development ending in seed dormancy GO:0009793
The process whose specific outcome is the progression of the embryo over time, from zygote formation to the end of seed dormancy. An example of this process is found in Arabidopsis thaliana.
2 Q9M884 (/IMP) Q9M884 (/IMP)
Fungal-type cell wall organization GO:0031505
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the fungal-type cell wall.
2 P34948 (/IMP) P34948 (/IMP)
Response to cobalt ion GO:0032025
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cobalt ion stimulus.
2 Q9M884 (/IEP) Q9M884 (/IEP)
Mannose to fructose-6-phosphate metabolic process GO:0061611
The chemical reactions and pathways in which mannose, the aldohexose manno-hexose, is converted to fructose-6-phosphate.
2 Q924M7 (/IMP) Q924M7 (/IMP)
Glycolytic process from mannose through fructose-6-phosphate GO:0061619
The chemical reactions and pathways resulting in the breakdown of mannose into pyruvate, occurring through a fructose-6-phosphate intermediate, with the concomitant production of ATP and NADH.
2 Q924M7 (/IC) Q924M7 (/IC)
Liver development GO:0001889
The process whose specific outcome is the progression of the liver over time, from its formation to the mature structure. The liver is an exocrine gland which secretes bile and functions in metabolism of protein and carbohydrate and fat, synthesizes substances involved in the clotting of the blood, synthesizes vitamin A, detoxifies poisonous substances, stores glycogen, and breaks down worn-out erythrocytes.
1 Q3ZB95 (/IMP)
GDP-mannose biosynthetic process GO:0009298
The chemical reactions and pathways resulting in the formation of GDP-mannose, a substance composed of mannose in glycosidic linkage with guanosine diphosphate.
1 Q54PA0 (/ISS)
Response to absence of light GO:0009646
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an absence of light stimuli.
1 Q9FZH5 (/IEP)
Response to sucrose GO:0009744
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a sucrose stimulus.
1 Q9FZH5 (/IEP)
Mannose biosynthetic process GO:0019307
The chemical reactions and pathways resulting in the formation of mannose, the aldohexose manno-hexose, the C-2 epimer of glucose.
1 Q4Q5C3 (/EXP)
L-ascorbic acid biosynthetic process GO:0019853
The chemical reactions and pathways resulting in the formation of L-ascorbic acid; L-ascorbic acid ionizes to give L-ascorbate, (2R)-2-
1 Q9FZH5 (/IMP)
Chordate embryonic development GO:0043009
The process whose specific outcome is the progression of the embryo over time, from zygote formation through a stage including a notochord and neural tube until birth or egg hatching.
1 Q3ZB95 (/IMP)
Response to DDT GO:0046680
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a DDT stimulus. DDT, dichlorodiphenyltrichloroethane, is a chlorinated hydrocarbon pesticide moderately toxic to humans and other animals.
1 Q9FZH5 (/IEP)
Chondrocyte morphogenesis GO:0090171
The process in which the structures of a chondrocyte are generated and organized. This process occurs while the initially relatively unspecialized cell is acquiring the specialized features of a chondrocyte.
1 Q3ZB95 (/IGI)

There are 5 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
5 P29952 (/HDA) P29952 (/HDA) P29952 (/HDA) P29952 (/HDA) P29952 (/HDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
5 P29952 (/HDA) P29952 (/HDA) P29952 (/HDA) P29952 (/HDA) P29952 (/HDA)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
2 P34949 (/TAS) P34949 (/TAS)
Extracellular exosome GO:0070062
A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.
2 P34949 (/HDA) P34949 (/HDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
1 Q4Q5C3 (/EXP)
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