The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:

"
Calponin-like domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
« Back to all FunFams

FunFam 24: Hook homolog 3 (Drosophila)

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 16 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO TermAnnotationsEvidence
Microtubule binding GO:0008017
Interacting selectively and non-covalently with microtubules, filaments composed of tubulin monomers.
19 B0WPU9 (/ISS) B3MNR6 (/ISS) B3NL60 (/ISS) B4G831 (/ISS) B4I5P7 (/ISS) B4JAL5 (/ISS) B4KE73 (/ISS) B4N1C2 (/ISS) B4PAF2 (/ISS) B4Q9E6 (/ISS)
(9 more)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
8 D3ZB48 (/IPI) Q7TMK6 (/IPI) Q86VS8 (/IPI) Q86VS8 (/IPI) Q8BIL5 (/IPI) Q8BUK6 (/IPI) Q96ED9 (/IPI) Q9UJC3 (/IPI)
Microtubule binding GO:0008017
Interacting selectively and non-covalently with microtubules, filaments composed of tubulin monomers.
4 Q24185 (/IDA) Q86VS8 (/IDA) Q86VS8 (/IDA) Q8BIL5 (/IDA)
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
4 Q86VS8 (/IPI) Q86VS8 (/IPI) Q96ED9 (/IPI) Q9UJC3 (/IPI)
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
3 Q7TMK6 (/ISO) Q8BIL5 (/ISO) Q8BUK6 (/ISO)
Microtubule binding GO:0008017
Interacting selectively and non-covalently with microtubules, filaments composed of tubulin monomers.
2 Q8BIL5 (/ISO) Q8BUK6 (/ISO)
Dynactin binding GO:0034452
Interacting selectively and non-covalently with any part of a dynactin complex; dynactin is a large protein complex that activates dynein-based motor activity.
2 Q86VS8 (/IDA) Q86VS8 (/IDA)
Dynein light chain binding GO:0045503
Interacting selectively and non-covalently with a light chain of the dynein complex.
2 Q86VS8 (/IPI) Q86VS8 (/IPI)
Dynein intermediate chain binding GO:0045505
Interacting selectively and non-covalently with an intermediate chain of the dynein complex.
2 Q86VS8 (/IDA) Q86VS8 (/IDA)
Actin binding GO:0003779
Interacting selectively and non-covalently with monomeric or multimeric forms of actin, including actin filaments.
1 Q8BIL5 (/IDA)
Showing 1 to 10 of 16 entries

There are 36 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO TermAnnotationsEvidence
Endocytosis GO:0006897
A vesicle-mediated transport process in which cells take up external materials or membrane constituents by the invagination of a small region of the plasma membrane to form a new membrane-bounded vesicle.
19 B0WPU9 (/ISS) B3MNR6 (/ISS) B3NL60 (/ISS) B4G831 (/ISS) B4I5P7 (/ISS) B4JAL5 (/ISS) B4KE73 (/ISS) B4N1C2 (/ISS) B4PAF2 (/ISS) B4Q9E6 (/ISS)
(9 more)
Cytoskeleton-dependent intracellular transport GO:0030705
The directed movement of substances along cytoskeletal fibers such as microfilaments or microtubules within a cell.
19 B0WPU9 (/ISS) B3MNR6 (/ISS) B3NL60 (/ISS) B4G831 (/ISS) B4I5P7 (/ISS) B4JAL5 (/ISS) B4KE73 (/ISS) B4N1C2 (/ISS) B4PAF2 (/ISS) B4Q9E6 (/ISS)
(9 more)
Determination of adult lifespan GO:0008340
The control of viability and duration in the adult phase of the life-cycle.
11 B3MNR6 (/ISS) B3NL60 (/ISS) B4G831 (/ISS) B4I5P7 (/ISS) B4JAL5 (/ISS) B4KE73 (/ISS) B4N1C2 (/ISS) B4PAF2 (/ISS) B4Q9E6 (/ISS) B4Q9E6 (/ISS)
(1 more)
Endosome organization GO:0007032
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of endosomes.
7 Q5TZ80 (/ISS) Q5ZJ27 (/ISS) Q6GQ73 (/ISS) Q6NRB0 (/ISS) Q7TMK6 (/ISS) Q8BIL5 (/ISS) Q8BUK6 (/ISS)
Lysosome organization GO:0007040
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a lysosome. A lysosome is a cytoplasmic, membrane-bounded organelle that is found in most animal cells and that contains a variety of hydrolases.
7 Q5TZ80 (/ISS) Q5ZJ27 (/ISS) Q6GQ73 (/ISS) Q6NRB0 (/ISS) Q7TMK6 (/ISS) Q8BIL5 (/ISS) Q8BUK6 (/ISS)
Endosome to lysosome transport GO:0008333
The directed movement of substances from endosomes to lysosomes.
7 Q5TZ80 (/ISS) Q5ZJ27 (/ISS) Q6GQ73 (/ISS) Q6NRB0 (/ISS) Q7TMK6 (/ISS) Q8BIL5 (/ISS) Q8BUK6 (/ISS)
Early endosome to late endosome transport GO:0045022
The directed movement of substances, in membrane-bounded vesicles, from the early sorting endosomes to the late sorting endosomes; transport occurs along microtubules and can be experimentally blocked with microtubule-depolymerizing drugs.
7 Q5TZ80 (/ISS) Q5ZJ27 (/ISS) Q6GQ73 (/ISS) Q6NRB0 (/ISS) Q7TMK6 (/ISS) Q8BIL5 (/ISS) Q8BUK6 (/ISS)
Endosome organization GO:0007032
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of endosomes.
4 Q86VS8 (/IMP) Q86VS8 (/IMP) Q96ED9 (/IMP) Q9UJC3 (/IMP)
Lysosome organization GO:0007040
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a lysosome. A lysosome is a cytoplasmic, membrane-bounded organelle that is found in most animal cells and that contains a variety of hydrolases.
4 Q86VS8 (/IMP) Q86VS8 (/IMP) Q96ED9 (/IMP) Q9UJC3 (/IMP)
Endosome to lysosome transport GO:0008333
The directed movement of substances from endosomes to lysosomes.
4 Q86VS8 (/IMP) Q86VS8 (/IMP) Q96ED9 (/IMP) Q9UJC3 (/IMP)
Showing 1 to 10 of 36 entries

There are 22 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO TermAnnotationsEvidence
Endosome GO:0005768
A vacuole to which materials ingested by endocytosis are delivered.
19 B0WPU9 (/ISS) B3MNR6 (/ISS) B3NL60 (/ISS) B4G831 (/ISS) B4I5P7 (/ISS) B4JAL5 (/ISS) B4KE73 (/ISS) B4N1C2 (/ISS) B4PAF2 (/ISS) B4Q9E6 (/ISS)
(9 more)
Synapse GO:0045202
The junction between a nerve fiber of one neuron and another neuron, muscle fiber or glial cell. As the nerve fiber approaches the synapse it enlarges into a specialized structure, the presynaptic nerve ending, which contains mitochondria and synaptic vesicles. At the tip of the nerve ending is the presynaptic membrane; facing it, and separated from it by a minute cleft (the synaptic cleft) is a specialized area of membrane on the receiving cell, known as the postsynaptic membrane. In response to the arrival of nerve impulses, the presynaptic nerve ending secretes molecules of neurotransmitters into the synaptic cleft. These diffuse across the cleft and transmit the signal to the postsynaptic membrane.
11 B3MNR6 (/ISS) B3NL60 (/ISS) B4G831 (/ISS) B4I5P7 (/ISS) B4JAL5 (/ISS) B4KE73 (/ISS) B4N1C2 (/ISS) B4PAF2 (/ISS) B4Q9E6 (/ISS) B4Q9E6 (/ISS)
(1 more)
FHF complex GO:0070695
A protein complex that is composed of AKTIP/FTS, FAM160A2/p107FHIP, and one or more members of the Hook family of proteins, HOOK1, HOOK2, and HOOK3. The complex is thought to promote vesicle trafficking and/or fusion, and associates with the homotypic vesicular sorting complex (the HOPS complex).
5 Q5TZ80 (/ISS) Q5ZJ27 (/ISS) Q6NRB0 (/ISS) Q7TMK6 (/ISS) Q8BIL5 (/ISS)
FHF complex GO:0070695
A protein complex that is composed of AKTIP/FTS, FAM160A2/p107FHIP, and one or more members of the Hook family of proteins, HOOK1, HOOK2, and HOOK3. The complex is thought to promote vesicle trafficking and/or fusion, and associates with the homotypic vesicular sorting complex (the HOPS complex).
4 Q86VS8 (/IDA) Q86VS8 (/IDA) Q96ED9 (/IDA) Q9UJC3 (/IDA)
FHF complex GO:0070695
A protein complex that is composed of AKTIP/FTS, FAM160A2/p107FHIP, and one or more members of the Hook family of proteins, HOOK1, HOOK2, and HOOK3. The complex is thought to promote vesicle trafficking and/or fusion, and associates with the homotypic vesicular sorting complex (the HOPS complex).
3 Q7TMK6 (/ISO) Q8BIL5 (/ISO) Q8BUK6 (/ISO)
Pericentriolar material GO:0000242
A network of small fibers that surrounds the centrioles in cells; contains the microtubule nucleating activity of the centrosome.
2 Q86VS8 (/ISS) Q86VS8 (/ISS)
Cis-Golgi network GO:0005801
The network of interconnected tubular and cisternal structures located at the convex side of the Golgi apparatus, which abuts the endoplasmic reticulum.
2 Q86VS8 (/IDA) Q86VS8 (/IDA)
Centrosome GO:0005813
A structure comprised of a core structure (in most organisms, a pair of centrioles) and peripheral material from which a microtubule-based structure, such as a spindle apparatus, is organized. Centrosomes occur close to the nucleus during interphase in many eukaryotic cells, though in animal cells it changes continually during the cell-division cycle.
2 Q8BUK6 (/IDA) Q96ED9 (/IDA)
Centrosome GO:0005813
A structure comprised of a core structure (in most organisms, a pair of centrioles) and peripheral material from which a microtubule-based structure, such as a spindle apparatus, is organized. Centrosomes occur close to the nucleus during interphase in many eukaryotic cells, though in animal cells it changes continually during the cell-division cycle.
2 Q86VS8 (/ISS) Q86VS8 (/ISS)
Pericentriolar material GO:0000242
A network of small fibers that surrounds the centrioles in cells; contains the microtubule nucleating activity of the centrosome.
1 Q8BUK6 (/IDA)
Showing 1 to 10 of 22 entries
CATH-Gene3D is a Global Biodata Core Resource Learn more...