View in Gene3D

CATH Superfamily 1.10.405.10

Guanine Nucleotide Dissociation Inhibitor, domain 1

The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:

"
Guanine Nucleotide Dissociation Inhibitor, domain 1
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
« Back to all FunFams

FunFam 5: Amine oxidase [flavin-containing]

There are 1 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Monoamine oxidase. [EC: 1.4.3.4]
RCH(2)NHR' + H(2)O + O(2) = RCHO + R'NH(2) + H(2)O(2).
  • Catalyzes the oxidative deamination of neurotransmitters and biogenic amines.
  • Acts on primary amines, and also on some secondary and tertiary amines.
  • It differs from EC 1.4.3.21, as it can oxidize secondary and tertiary amines but not methylamine.
  • Inhibited by acetylenic compounds such as chlorgyline, 1-deprenyl and pargyline but, unlike EC 1.4.3.21 and EC 1.4.3.22, it is not inhibited by semicarbazide.
  • Formerly EC 1.4.3.9.
 17 A0A2J8WIP2 A0A2J8WIP2 P19643 P21396 P21397 P21397 P27338 P58027 Q53YE7 Q53YE7
(7 more...)
CATH-Gene3D is a Global Biodata Core Resource Learn more...