The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:
"yeast vps74-n-term truncation variant domain like
".
FunFam 2: Vacuolar sorting-associated 74 protein
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 3 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Enzyme binding GO:0019899
Interacting selectively and non-covalently with any enzyme.
|
6 | Q06385 (/IPI) Q06385 (/IPI) Q06385 (/IPI) Q06385 (/IPI) Q06385 (/IPI) Q06385 (/IPI) |
Phosphatidylinositol-4-phosphate binding GO:0070273
Interacting selectively and non-covalently with phosphatidylinositol-4-phosphate, a derivative of phosphatidylinositol in which the inositol ring is phosphorylated at the 4' position.
|
6 | Q06385 (/IDA) Q06385 (/IDA) Q06385 (/IDA) Q06385 (/IDA) Q06385 (/IDA) Q06385 (/IDA) |
Phosphatidylinositol-4-phosphate binding GO:0070273
Interacting selectively and non-covalently with phosphatidylinositol-4-phosphate, a derivative of phosphatidylinositol in which the inositol ring is phosphorylated at the 4' position.
|
6 | Q06385 (/IMP) Q06385 (/IMP) Q06385 (/IMP) Q06385 (/IMP) Q06385 (/IMP) Q06385 (/IMP) |
There are 9 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Protein N-linked glycosylation GO:0006487
A protein glycosylation process in which a carbohydrate or carbohydrate derivative unit is added to a protein via the N4 atom of peptidyl-asparagine, the omega-N of arginine, or the N1' atom peptidyl-tryptophan.
|
6 | Q06385 (/IMP) Q06385 (/IMP) Q06385 (/IMP) Q06385 (/IMP) Q06385 (/IMP) Q06385 (/IMP) |
Retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum GO:0006890
The directed movement of substances from the Golgi back to the endoplasmic reticulum, mediated by vesicles bearing specific protein coats such as COPI or COG.
|
6 | Q06385 (/IMP) Q06385 (/IMP) Q06385 (/IMP) Q06385 (/IMP) Q06385 (/IMP) Q06385 (/IMP) |
Endoplasmic reticulum unfolded protein response GO:0030968
The series of molecular signals generated as a consequence of the presence of unfolded proteins in the endoplasmic reticulum (ER) or other ER-related stress; results in changes in the regulation of transcription and translation.
|
6 | Q06385 (/IMP) Q06385 (/IMP) Q06385 (/IMP) Q06385 (/IMP) Q06385 (/IMP) Q06385 (/IMP) |
Protein localization to Golgi apparatus GO:0034067
A process in which a protein is transported to, or maintained in, a location within the Golgi apparatus.
|
6 | Q06385 (/IMP) Q06385 (/IMP) Q06385 (/IMP) Q06385 (/IMP) Q06385 (/IMP) Q06385 (/IMP) |
Protein O-linked mannosylation GO:0035269
The transfer of mannose from dolichyl activated mannose to the hydroxyl group of a seryl or threonyl residue of a protein acceptor molecule, to form an O-linked protein-sugar linkage.
|
6 | Q06385 (/IMP) Q06385 (/IMP) Q06385 (/IMP) Q06385 (/IMP) Q06385 (/IMP) Q06385 (/IMP) |
Regulation of phosphatidylinositol dephosphorylation GO:0060304
Any process that modulates the frequency, rate or extent of the chemical reaction involving the removal of one or more phosphate groups from a phosphatidylinositol.
|
6 | Q06385 (/IMP) Q06385 (/IMP) Q06385 (/IMP) Q06385 (/IMP) Q06385 (/IMP) Q06385 (/IMP) |
Protein targeting to vacuole GO:0006623
The process of directing proteins towards the vacuole, usually using signals contained within the protein.
|
3 | G4NE21 (/ISS) G4NE21 (/ISS) G4NE21 (/ISS) |
Retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum GO:0006890
The directed movement of substances from the Golgi back to the endoplasmic reticulum, mediated by vesicles bearing specific protein coats such as COPI or COG.
|
1 | O14205 (/ISO) |
Endoplasmic reticulum unfolded protein response GO:0030968
The series of molecular signals generated as a consequence of the presence of unfolded proteins in the endoplasmic reticulum (ER) or other ER-related stress; results in changes in the regulation of transcription and translation.
|
1 | O14205 (/ISO) |
There are 11 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
7 | O14205 (/HDA) Q06385 (/HDA) Q06385 (/HDA) Q06385 (/HDA) Q06385 (/HDA) Q06385 (/HDA) Q06385 (/HDA) |
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
6 | Q06385 (/HDA) Q06385 (/HDA) Q06385 (/HDA) Q06385 (/HDA) Q06385 (/HDA) Q06385 (/HDA) |
Golgi apparatus GO:0005794
A compound membranous cytoplasmic organelle of eukaryotic cells, consisting of flattened, ribosome-free vesicles arranged in a more or less regular stack. The Golgi apparatus differs from the endoplasmic reticulum in often having slightly thicker membranes, appearing in sections as a characteristic shallow semicircle so that the convex side (cis or entry face) abuts the endoplasmic reticulum, secretory vesicles emerging from the concave side (trans or exit face). In vertebrate cells there is usually one such organelle, while in invertebrates and plants, where they are known usually as dictyosomes, there may be several scattered in the cytoplasm. The Golgi apparatus processes proteins produced on the ribosomes of the rough endoplasmic reticulum; such processing includes modification of the core oligosaccharides of glycoproteins, and the sorting and packaging of proteins for transport to a variety of cellular locations. Three different regions of the Golgi are now recognized both in terms of structure and function: cis, in the vicinity of the cis face, trans, in the vicinity of the trans face, and medial, lying between the cis and trans regions.
|
6 | Q06385 (/IDA) Q06385 (/IDA) Q06385 (/IDA) Q06385 (/IDA) Q06385 (/IDA) Q06385 (/IDA) |
Golgi medial cisterna GO:0005797
The middle Golgi cisterna (or cisternae).
|
6 | Q06385 (/IDA) Q06385 (/IDA) Q06385 (/IDA) Q06385 (/IDA) Q06385 (/IDA) Q06385 (/IDA) |
Trans-Golgi network GO:0005802
The network of interconnected tubular and cisternal structures located within the Golgi apparatus on the side distal to the endoplasmic reticulum, from which secretory vesicles emerge. The trans-Golgi network is important in the later stages of protein secretion where it is thought to play a key role in the sorting and targeting of secreted proteins to the correct destination.
|
6 | Q06385 (/IDA) Q06385 (/IDA) Q06385 (/IDA) Q06385 (/IDA) Q06385 (/IDA) Q06385 (/IDA) |
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
6 | Q06385 (/IDA) Q06385 (/IDA) Q06385 (/IDA) Q06385 (/IDA) Q06385 (/IDA) Q06385 (/IDA) |
Extrinsic component of membrane GO:0019898
The component of a membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.
|
6 | Q06385 (/IDA) Q06385 (/IDA) Q06385 (/IDA) Q06385 (/IDA) Q06385 (/IDA) Q06385 (/IDA) |
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
3 | G4NE21 (/ISS) G4NE21 (/ISS) G4NE21 (/ISS) |
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
3 | G4NE21 (/ISS) G4NE21 (/ISS) G4NE21 (/ISS) |
Golgi apparatus GO:0005794
A compound membranous cytoplasmic organelle of eukaryotic cells, consisting of flattened, ribosome-free vesicles arranged in a more or less regular stack. The Golgi apparatus differs from the endoplasmic reticulum in often having slightly thicker membranes, appearing in sections as a characteristic shallow semicircle so that the convex side (cis or entry face) abuts the endoplasmic reticulum, secretory vesicles emerging from the concave side (trans or exit face). In vertebrate cells there is usually one such organelle, while in invertebrates and plants, where they are known usually as dictyosomes, there may be several scattered in the cytoplasm. The Golgi apparatus processes proteins produced on the ribosomes of the rough endoplasmic reticulum; such processing includes modification of the core oligosaccharides of glycoproteins, and the sorting and packaging of proteins for transport to a variety of cellular locations. Three different regions of the Golgi are now recognized both in terms of structure and function: cis, in the vicinity of the cis face, trans, in the vicinity of the trans face, and medial, lying between the cis and trans regions.
|
1 | O14205 (/ISO) |
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
1 | O14205 (/HDA) |