The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:
"Tetracycline Repressor, domain 2
".
FunFam 64: TetR family transcriptional regulator
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 6 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Transcription regulatory region DNA binding GO:0044212
Interacting selectively and non-covalently with a DNA region that regulates the transcription of a region of DNA, which may be a gene, cistron, or operon. Binding may occur as a sequence specific interaction or as an interaction observed only once a factor has been recruited to the DNA by other factors.
|
10 | G3XCU9 (/IDA) G3XCU9 (/IDA) G3XCU9 (/IDA) G3XCU9 (/IDA) G3XCU9 (/IDA) Q9RG61 (/IDA) Q9RG61 (/IDA) Q9RG61 (/IDA) Q9RG61 (/IDA) Q9RG61 (/IDA) |
|
Transcription regulatory region sequence-specific DNA binding GO:0000976
Interacting selectively and non-covalently with a specific sequence of DNA that is part of a regulatory region that controls transcription of that section of the DNA. The transcribed region might be described as a gene, cistron, or operon.
|
5 | G3XCU9 (/IDA) G3XCU9 (/IDA) G3XCU9 (/IDA) G3XCU9 (/IDA) G3XCU9 (/IDA) |
|
Transcription regulatory region sequence-specific DNA binding GO:0000976
Interacting selectively and non-covalently with a specific sequence of DNA that is part of a regulatory region that controls transcription of that section of the DNA. The transcribed region might be described as a gene, cistron, or operon.
|
5 | G3XCU9 (/IMP) G3XCU9 (/IMP) G3XCU9 (/IMP) G3XCU9 (/IMP) G3XCU9 (/IMP) |
|
DNA-binding transcription repressor activity GO:0001217
Interacting selectively and non-covalently with a specific DNA sequence in order to stop, prevent, or reduce the frequency, rate or extent of transcription by a RNA polymerase.
|
5 | G3XCU9 (/IDA) G3XCU9 (/IDA) G3XCU9 (/IDA) G3XCU9 (/IDA) G3XCU9 (/IDA) |
|
DNA-binding transcription repressor activity GO:0001217
Interacting selectively and non-covalently with a specific DNA sequence in order to stop, prevent, or reduce the frequency, rate or extent of transcription by a RNA polymerase.
|
5 | G3XCU9 (/IMP) G3XCU9 (/IMP) G3XCU9 (/IMP) G3XCU9 (/IMP) G3XCU9 (/IMP) |
|
Sequence-specific DNA binding GO:0043565
Interacting selectively and non-covalently with DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding.
|
5 | G3XCU9 (/IDA) G3XCU9 (/IDA) G3XCU9 (/IDA) G3XCU9 (/IDA) G3XCU9 (/IDA) |
There are 5 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Regulation of transcription, DNA-templated GO:0006355
Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.
|
10 | G3XCU9 (/IDA) G3XCU9 (/IDA) G3XCU9 (/IDA) G3XCU9 (/IDA) G3XCU9 (/IDA) Q9RG61 (/IDA) Q9RG61 (/IDA) Q9RG61 (/IDA) Q9RG61 (/IDA) Q9RG61 (/IDA) |
|
Negative regulation of transporter activity GO:0032410
Any process that stops or reduces the activity of a transporter.
|
10 | G3XCU9 (/IMP) G3XCU9 (/IMP) G3XCU9 (/IMP) G3XCU9 (/IMP) G3XCU9 (/IMP) Q9RG61 (/IMP) Q9RG61 (/IMP) Q9RG61 (/IMP) Q9RG61 (/IMP) Q9RG61 (/IMP) |
|
Negative regulation of transmembrane transport GO:0034763
Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of a solute from one side of a membrane to the other.
|
10 | G3XCU9 (/IMP) G3XCU9 (/IMP) G3XCU9 (/IMP) G3XCU9 (/IMP) G3XCU9 (/IMP) Q9RG61 (/IMP) Q9RG61 (/IMP) Q9RG61 (/IMP) Q9RG61 (/IMP) Q9RG61 (/IMP) |
|
Negative regulation of transcription, DNA-templated GO:0045892
Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription.
|
10 | G3XCU9 (/IMP) G3XCU9 (/IMP) G3XCU9 (/IMP) G3XCU9 (/IMP) G3XCU9 (/IMP) Q9RG61 (/IMP) Q9RG61 (/IMP) Q9RG61 (/IMP) Q9RG61 (/IMP) Q9RG61 (/IMP) |
|
Negative regulation of transcription, DNA-templated GO:0045892
Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription.
|
5 | G3XCU9 (/IDA) G3XCU9 (/IDA) G3XCU9 (/IDA) G3XCU9 (/IDA) G3XCU9 (/IDA) |
There are 2 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Protein-DNA complex GO:0032993
A macromolecular complex containing both protein and DNA molecules.
|
5 | G3XCU9 (/IDA) G3XCU9 (/IDA) G3XCU9 (/IDA) G3XCU9 (/IDA) G3XCU9 (/IDA) |
|
Protein-DNA complex GO:0032993
A macromolecular complex containing both protein and DNA molecules.
|
5 | G3XCU9 (/IMP) G3XCU9 (/IMP) G3XCU9 (/IMP) G3XCU9 (/IMP) G3XCU9 (/IMP) |
