The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:
"Tetracycline Repressor, domain 2
".
FunFam 18: Transcriptional regulator LuxT
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 5 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
DNA-binding transcription factor activity GO:0003700
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons.
|
7 | Q9KL32 (/ISS) Q9KL32 (/ISS) Q9KL32 (/ISS) Q9KL32 (/ISS) Q9KL32 (/ISS) Q9KL32 (/ISS) Q9KL32 (/ISS) |
|
Transcription regulatory region sequence-specific DNA binding GO:0000976
Interacting selectively and non-covalently with a specific sequence of DNA that is part of a regulatory region that controls transcription of that section of the DNA. The transcribed region might be described as a gene, cistron, or operon.
|
4 | Q7MFA2 (/IDA) Q7MFA2 (/IDA) Q7MFA2 (/IDA) Q7MFA2 (/IDA) |
|
Transcription regulatory region sequence-specific DNA binding GO:0000976
Interacting selectively and non-covalently with a specific sequence of DNA that is part of a regulatory region that controls transcription of that section of the DNA. The transcribed region might be described as a gene, cistron, or operon.
|
4 | Q7MFA2 (/IPI) Q7MFA2 (/IPI) Q7MFA2 (/IPI) Q7MFA2 (/IPI) |
|
DNA-binding transcription repressor activity GO:0001217
Interacting selectively and non-covalently with a specific DNA sequence in order to stop, prevent, or reduce the frequency, rate or extent of transcription by a RNA polymerase.
|
4 | Q7MFA2 (/IDA) Q7MFA2 (/IDA) Q7MFA2 (/IDA) Q7MFA2 (/IDA) |
|
DNA-binding transcription repressor activity GO:0001217
Interacting selectively and non-covalently with a specific DNA sequence in order to stop, prevent, or reduce the frequency, rate or extent of transcription by a RNA polymerase.
|
4 | Q7MFA2 (/IPI) Q7MFA2 (/IPI) Q7MFA2 (/IPI) Q7MFA2 (/IPI) |
There are 6 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Regulation of transcription, DNA-templated GO:0006355
Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.
|
7 | Q9KL32 (/ISS) Q9KL32 (/ISS) Q9KL32 (/ISS) Q9KL32 (/ISS) Q9KL32 (/ISS) Q9KL32 (/ISS) Q9KL32 (/ISS) |
|
Signal transduction GO:0007165
The cellular process in which a signal is conveyed to trigger a change in the activity or state of a cell. Signal transduction begins with reception of a signal (e.g. a ligand binding to a receptor or receptor activation by a stimulus such as light), or for signal transduction in the absence of ligand, signal-withdrawal or the activity of a constitutively active receptor. Signal transduction ends with regulation of a downstream cellular process, e.g. regulation of transcription or regulation of a metabolic process. Signal transduction covers signaling from receptors located on the surface of the cell and signaling via molecules located within the cell. For signaling between cells, signal transduction is restricted to events at and within the receiving cell.
|
5 | D0WWP7 (/IMP) D0WWP7 (/IMP) D0WWP7 (/IMP) D0WWP7 (/IMP) D0WWP7 (/IMP) |
|
Positive regulation of serine-type peptidase activity GO:1902573
Any process that activates or increases the frequency, rate or extent of serine-type peptidase activity.
|
5 | D0WWP7 (/IMP) D0WWP7 (/IMP) D0WWP7 (/IMP) D0WWP7 (/IMP) D0WWP7 (/IMP) |
|
Positive regulation of cell motility GO:2000147
Any process that activates or increases the frequency, rate or extent of cell motility.
|
5 | D0WWP7 (/IMP) D0WWP7 (/IMP) D0WWP7 (/IMP) D0WWP7 (/IMP) D0WWP7 (/IMP) |
|
Negative regulation of transcription, DNA-templated GO:0045892
Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription.
|
4 | Q7MFA2 (/IDA) Q7MFA2 (/IDA) Q7MFA2 (/IDA) Q7MFA2 (/IDA) |
|
Negative regulation of transcription, DNA-templated GO:0045892
Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription.
|
4 | Q7MFA2 (/IEP) Q7MFA2 (/IEP) Q7MFA2 (/IEP) Q7MFA2 (/IEP) |
There are 2 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Protein-DNA complex GO:0032993
A macromolecular complex containing both protein and DNA molecules.
|
4 | Q7MFA2 (/IDA) Q7MFA2 (/IDA) Q7MFA2 (/IDA) Q7MFA2 (/IDA) |
|
Protein-DNA complex GO:0032993
A macromolecular complex containing both protein and DNA molecules.
|
4 | Q7MFA2 (/IPI) Q7MFA2 (/IPI) Q7MFA2 (/IPI) Q7MFA2 (/IPI) |
