The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:

"
Clc chloride channel
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 5: H(+)/Cl(-) exchange transporter ClcA

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 4 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Solute:proton antiporter activity GO:0015299
Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: solute(out) + H+(in) = solute(in) + H+(out).
92 P37019 (/IDA) P37019 (/IDA) P37019 (/IDA) P37019 (/IDA) P37019 (/IDA) P37019 (/IDA) P37019 (/IDA) P37019 (/IDA) P37019 (/IDA) P37019 (/IDA)
(82 more)
Chloride ion binding GO:0031404
Interacting selectively and non-covalently with chloride ions (Cl-).
92 P37019 (/IDA) P37019 (/IDA) P37019 (/IDA) P37019 (/IDA) P37019 (/IDA) P37019 (/IDA) P37019 (/IDA) P37019 (/IDA) P37019 (/IDA) P37019 (/IDA)
(82 more)
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
92 P37019 (/IPI) P37019 (/IPI) P37019 (/IPI) P37019 (/IPI) P37019 (/IPI) P37019 (/IPI) P37019 (/IPI) P37019 (/IPI) P37019 (/IPI) P37019 (/IPI)
(82 more)
Anion binding GO:0043168
Interacting selectively and non-covalently with anions, charged atoms or groups of atoms with a net negative charge.
92 P37019 (/IDA) P37019 (/IDA) P37019 (/IDA) P37019 (/IDA) P37019 (/IDA) P37019 (/IDA) P37019 (/IDA) P37019 (/IDA) P37019 (/IDA) P37019 (/IDA)
(82 more)

There are 2 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Chloride transport GO:0006821
The directed movement of chloride into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
92 P37019 (/IDA) P37019 (/IDA) P37019 (/IDA) P37019 (/IDA) P37019 (/IDA) P37019 (/IDA) P37019 (/IDA) P37019 (/IDA) P37019 (/IDA) P37019 (/IDA)
(82 more)
Nitrate transport GO:0015706
The directed movement of nitrate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
92 P37019 (/IDA) P37019 (/IDA) P37019 (/IDA) P37019 (/IDA) P37019 (/IDA) P37019 (/IDA) P37019 (/IDA) P37019 (/IDA) P37019 (/IDA) P37019 (/IDA)
(82 more)

There are 2 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
92 P37019 (/IDA) P37019 (/IDA) P37019 (/IDA) P37019 (/IDA) P37019 (/IDA) P37019 (/IDA) P37019 (/IDA) P37019 (/IDA) P37019 (/IDA) P37019 (/IDA)
(82 more)
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
92 P37019 (/IDA) P37019 (/IDA) P37019 (/IDA) P37019 (/IDA) P37019 (/IDA) P37019 (/IDA) P37019 (/IDA) P37019 (/IDA) P37019 (/IDA) P37019 (/IDA)
(82 more)
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