The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:

"
High mobility group box domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
SC:1transcription factor 7 isoform X2Putative transcription factor SOX-6Transcription factor SOXHigh mobility group protein B3nucleolar transcription factor 1 isoform X2HMG box-containing protein 1nucleolar transcription factor 1 isoform X2Maelstrom spermatogenic transposon silencerMutant transcription factor sox9aSC:2HMG box transcription factor BBXFACT complex subunit SSRP1High mobility group protein B2WD repeat and HMG-box DNA-binding protein 1Transcription factor A, mitochondrialTranscription factor A, mitochondrialHigh mobility group protein B1SC:3TOX high mobility group box family member 3nucleolar transcription factor 1 isoform X1nucleolar transcription factor 1 isoform X2SC:4Histone-lysine N-methyltransferasehigh mobility group protein B3PMS1 homolog 1, mismatch repair system componenttranscription factor Sox-2Transcription factor SOX-10High mobility group protein B1transcription factor SOX-7Capicua transcriptional repressor bPutative SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1axial regulator YABBY 5-likehigh mobility group protein B1Histone-lysine N-methyltransferase NSD2HMG domain-containing protein 3 isoform X2Transcription factor SOX-30nucleolar transcription factor 1 isoform X2HMG domain-containing protein 4 isoform X1High mobility group protein 20AFACT complex subunit SSRP1nucleolar transcription factor 1 isoform X1SWI/SNF-related matrix-associated regulator of chromatin subfamily E member 1-relatedhigh mobility group protein DHigh mobility group protein B2High mobility group box 4protein CRABS CLAW isoform X3SRY (sex determining region Y)-box 32HMG box family proteinHigh mobility group protein 1.2High mobility group B1High mobility group box 4Axial regulator YABBYPutative SWI/SNF-related matrix-associated actin-dependent regulator chromatin subfamily E memberRelated to NHP6B-nonhistone chromosomal proteinNuclear autoantigen Sp-100Transcription factor Sox-10Non-histone chromosomal protein 6 homologProtein CRABS CLAWSwi snf-related matrix-associated actin-dependent regulator ofHigh mobility group B protein 15Brahma-associated protein 111kDProtein maelstrom 2IXR1p Transcriptional repressorProtein pop-1Transcription factor proteinHigh mobility group protein B3Hmg-1.1High mobility group protein B3Nhp10pHigh mobility group familyLysine-specific histone demethylase Aof2, putativePolyBRoMo domain containingCBL-interacting protein kinase 33Uncharacterized protein, isoform AHigh mobility group proteinFACT complex subunit SSRP1High mobility group protein 1 homologSRY-related protein AMA1Capicua transcriptional repressor aAxial regulator YABBY 4SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1-relatedARS-binding factorIXR1p Transcriptional repressorARS-binding factorHigh mobility group protein B4, putativeMitochondrial transcription factor A, isoform BHigh mobility group B protein 13HMG type nucleosome/chromatin assembly factorChromatin-associated proteinProtein CBG16280Uncharacterized proteinSex-determining region Y proteinhigh mobility group B protein 7 isoform X1High mobility group protein 2HMG (High mobility group) box domain containing proteinHigh mobility group B protein 13AGAP002022-PAHigh mobility group B protein 4High mobility group protein-like tdp-1, putativeChromodomain helicase DNA binding protein 3Similar to transcription factor HMGUncharacterized proteinAxial regulator YABBY 4Sex-determining region Y proteinTestis-enriched HMG-box-containing protein 1Transcription factor Sox-7HMG box-containing proteinTranscription factor SOX-2High mobility group (HMG) DNA binding protein, putativeZgc:165618 proteintranscription factor proteinHigh mobility group protein-like tdp-1, putativeLysine-specific histone demethylase Aof2Polybromo 1Protein CBG16744Transcription factor 7-like 2GH11850pGcf1pAGAP005183-PAHMG box-containing protein 1Uncharacterized proteinHigh mobility group protein homolog TDP-1High mobility group protein homolog TDP-1protein polybromo-1 isoform X1LD26355pPMS1 homolog 1, mismatch repair system componentFACT complex subunit SSRP1Uncharacterized proteinSWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1Uncharacterized proteinSWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1High mobility group proteinHigh mobility group-T proteinUncharacterized proteinHMG box protein, putative (AFU_orthologue AFUA_1G10040)HMG box protein, putative (AFU_orthologue AFUA_1G10040)Protein CBG16280Uncharacterized proteinUncharacterized proteinHMG1/2 (High mobility group) box-containing proteinHistone-lysine N-methyltransferaseIsw-1Polybromo-1FACT complex subunit SSRP1YALI0D26972pPMS1 homolog 1, mismatch repair system componentProtein CBG07235Uncharacterized proteinProtein CBG08365Uncharacterized proteinHMG box family proteinHigh mobility group protein C, putativeMismatch-binding protein cmb1Kinetoplast-associated protein 4Uncharacterized proteinHMG transcription factor SoxCPredicted proteinUncharacterized proteinSRY-box 18Uncharacterized proteinHMG box family proteinUncharacterized proteinFACT complex subunit SSRP1HMG box-containing protein C28F2.11HMG box-containing protein C19G7.04Protein maelstromMaelstromUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinHMG box-containing protein C10F6.08cHigh mobility group B protein 14Chromosome 1, whole genome shotgun sequencePredicted proteinUncharacterized proteinPredicted proteinAFL219WpHigh mobility group proteinUncharacterized proteinUncharacterized proteinHigh mobility group box 2Uncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinHMGUpstream-binding factor 1-like protein 1Predicted proteinPredicted proteinHMGPredicted proteinFACT complex subunit SSRP1Putative high mobility group B protein 11FACT complex subunit SSRP1Uncharacterized proteinUncharacterized proteinPHDfinger domain-containing proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinPredicted protein
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FunFam 50: Nuclear autoantigen Sp-100

GO Diversity

Unique GO annotations
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EC Diversity

Unique EC annotations
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Species Diversity

Unique species annotations
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Statistics

Members
CATH Domains: 0
Sequences: 23
Annotations
Unique GO: 36
Unique EC: 0
Unique Species: 14
Representative
Rep ID: P23497/694-755
Inherited Annotations: 0
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