The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:
"atp-gated p2x4 ion channel
".
FunFam 11: P2X purinoceptor
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 2 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Extracellularly ATP-gated cation channel activity GO:0004931
Enables the transmembrane transfer of a cation by a channel that opens when ATP is bound by the channel complex or one of its constituent parts on the extracellular side of the plasma membrane.
|
4 | A0A2R8QGJ4 (/IDA) B3DIB7 (/IDA) F1QJ17 (/IDA) Q7SZM2 (/IDA) |
|
ATP-gated ion channel activity GO:0035381
Enables the transmembrane transfer of an ion by a channel that opens when ATP has been bound by the channel complex or one of its constituent parts.
|
4 | A0A2R8QGJ4 (/IDA) B3DIB7 (/IDA) F1QJ17 (/IDA) Q7SZM2 (/IDA) |
There are 3 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Cation transport GO:0006812
The directed movement of cations, atoms or small molecules with a net positive charge, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
|
4 | A0A2R8QGJ4 (/IDA) B3DIB7 (/IDA) F1QJ17 (/IDA) Q7SZM2 (/IDA) |
|
Macrophage chemotaxis GO:0048246
The movement of a macrophage in response to an external stimulus.
|
4 | A0A2R8QGJ4 (/IMP) B3DIB7 (/IMP) F1QJ17 (/IMP) Q7SZM2 (/IMP) |
|
Calcium ion import across plasma membrane GO:0098703
The directed movement of calcium ions from outside of a cell, across the plasma membrane and into the cytosol.
|
4 | A0A2R8QGJ4 (/IDA) B3DIB7 (/IDA) F1QJ17 (/IDA) Q7SZM2 (/IDA) |
There are 1 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
4 | A0A2R8QGJ4 (/IDA) B3DIB7 (/IDA) F1QJ17 (/IDA) Q7SZM2 (/IDA) |
