View in Gene3D

CATH Superfamily 1.10.287.850

HP0062-like domain

The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:

"
HP0062-like domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
« Back to all FunFams

FunFam 1: PE_PGRS39

There are 2 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Triacylglycerol lipase. [EC: 3.1.1.3]
Triacylglycerol + H(2)O = diacylglycerol + a carboxylate.
  • The pancreatic enzyme acts only on an ester-water interface; the outer ester links are preferentially hydrolyzed.
 289 A5U7B2 A5U7B2 A5U7B2 A5U7B2 A5U7B2 A5U7B2 A5U7B2 A5U7B2 A5U7B2 A5U7B2
(279 more...)
Phosphoglycerate mutase (2,3-diphosphoglycerate-independent). [EC: 5.4.2.12]
2-phospho-D-glycerate = 3-phospho-D-glycerate.
  • The enzymes from higher plants, algae, some fungi, nematodes, sponges, coelenterates, myriapods, arachnids, echinoderms, archaea and some bacteria (particularly Gram-positive) have maximum activity in the absence of 2,3-bisphospho-D-glycerate.
  • Cf. EC 5.4.2.11.
  • The reaction involves a phosphotransferase reaction to serine followed by transfer back to the glycerate at the other position.
  • Both metal ions are involved in the reaction.
  • Formerly EC 2.7.5.3 and EC 5.4.2.1.
 30 A0A0H3M298 A0A0H3M298 A0A0H3M298 A0A0H3M298 A0A0H3M298 A0A109SLU2 A0A109SLU2 A0A109SLU2 A0A109SLU2 A0A109SLU2
(20 more...)
CATH-Gene3D is a Global Biodata Core Resource Learn more...