The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:
"Acid-sensing ion channel domain
".
FunFam 4: Amiloride-sensitive Na+ channel
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 2 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Sodium channel activity GO:0005272
Enables the facilitated diffusion of a sodium ion (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism.
|
3 | O44940 (/ISS) Q7KT94 (/ISS) Q8SX41 (/ISS) |
|
Acid-sensing ion channel activity GO:0044736
Enables the transmembrane transfer of a sodium ion by a neuronal, voltage-insensitive channel that opens when an extracellular proton has been bound by the channel complex.
|
3 | O44940 (/IMP) Q7KT94 (/IMP) Q8SX41 (/IMP) |
There are 8 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Sodium ion transport GO:0006814
The directed movement of sodium ions (Na+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
|
3 | O44940 (/ISS) Q7KT94 (/ISS) Q8SX41 (/ISS) |
|
Mechanosensory behavior GO:0007638
Behavior that is dependent upon the sensation of a mechanical stimulus.
|
3 | O44940 (/IMP) Q7KT94 (/IMP) Q8SX41 (/IMP) |
|
Larval locomotory behavior GO:0008345
Locomotory behavior in a larval (immature) organism.
|
3 | O44940 (/IMP) Q7KT94 (/IMP) Q8SX41 (/IMP) |
|
Larval turning behavior GO:0035179
Fine-tuning the spatial position of a larva in response to variability in their environment. For example, reorientation of a larva in the direction of a food source.
|
3 | O44940 (/IMP) Q7KT94 (/IMP) Q8SX41 (/IMP) |
|
Behavioral response to pain GO:0048266
Any process that results in a change in the behavior of an organism as a result of a pain stimulus. Pain stimuli cause activation of nociceptors, peripheral receptors for pain, include receptors which are sensitive to painful mechanical stimuli, extreme heat or cold, and chemical stimuli.
|
3 | O44940 (/IMP) Q7KT94 (/IMP) Q8SX41 (/IMP) |
|
Detection of mechanical stimulus involved in sensory perception of pain GO:0050966
The series of events involved in the perception of pain in which a mechanical stimulus is received and converted into a molecular signal.
|
3 | O44940 (/IEP) Q7KT94 (/IEP) Q8SX41 (/IEP) |
|
Detection of mechanical stimulus involved in sensory perception of pain GO:0050966
The series of events involved in the perception of pain in which a mechanical stimulus is received and converted into a molecular signal.
|
3 | O44940 (/IMP) Q7KT94 (/IMP) Q8SX41 (/IMP) |
|
Negative regulation of feeding behavior GO:2000252
Any process that stops, prevents or reduces the frequency, rate or extent of feeding behavior.
|
3 | O44940 (/IMP) Q7KT94 (/IMP) Q8SX41 (/IMP) |
There are 2 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Integral component of membrane GO:0016021
The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
|
3 | O44940 (/ISS) Q7KT94 (/ISS) Q8SX41 (/ISS) |
|
Dendrite membrane GO:0032590
The portion of the plasma membrane surrounding a dendrite.
|
3 | O44940 (/IDA) Q7KT94 (/IDA) Q8SX41 (/IDA) |
