The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 58: Potassium sodium-activated channel subfamily T mem...

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 5 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Chloride-activated potassium channel activity GO:0070089
Enables the chloride concentration-regulatable energy-independent passage of potassium ions across a lipid bilayer down a concentration gradient.
6 Q6UVM3 (/IMP) Q6UVM3 (/IMP) Q6UVM3 (/IMP) Q6UVM3 (/IMP) Q6UVM3 (/IMP) Q6UVM4 (/IMP)
Potassium channel activity GO:0005267
Enables the facilitated diffusion of a potassium ion (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism.
3 D3YTU6 (/ISO) D3Z592 (/ISO) D3Z649 (/ISO)
Chloride-activated potassium channel activity GO:0070089
Enables the chloride concentration-regulatable energy-independent passage of potassium ions across a lipid bilayer down a concentration gradient.
3 D3YTU6 (/ISO) D3Z592 (/ISO) D3Z649 (/ISO)
Intracellular sodium activated potassium channel activity GO:0005228
Enables the transmembrane transfer of potassium by a channel that opens in response to stimulus by a sodium ion or ions. Transport by a channel involves facilitated diffusion of a solute (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel, without evidence for a carrier-mediated mechanism. Sodium activated potassium channels have distinctive properties, including a large single channel conductance, subconductance states, and a block of single channel currents at positive potentials, similar to inward rectification.
1 Q6UVM4 (/TAS)
ATP binding GO:0005524
Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
1 Q6UVM4 (/TAS)

There are 3 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Potassium ion export across plasma membrane GO:0097623
The directed movement of potassium ions from inside of a cell, across the plasma membrane and into the extracellular region.
6 Q6UVM3 (/IMP) Q6UVM3 (/IMP) Q6UVM3 (/IMP) Q6UVM3 (/IMP) Q6UVM3 (/IMP) Q6UVM4 (/IMP)
Potassium ion transport GO:0006813
The directed movement of potassium ions (K+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
3 D3YTU6 (/ISO) D3Z592 (/ISO) D3Z649 (/ISO)
Potassium ion export across plasma membrane GO:0097623
The directed movement of potassium ions from inside of a cell, across the plasma membrane and into the extracellular region.
3 D3YTU6 (/ISO) D3Z592 (/ISO) D3Z649 (/ISO)

There are 3 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
5 Q6UVM3 (/IDA) Q6UVM3 (/IDA) Q6UVM3 (/IDA) Q6UVM3 (/IDA) Q6UVM3 (/IDA)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
3 D3YTU6 (/ISO) D3Z592 (/ISO) D3Z649 (/ISO)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
1 Q6UVM4 (/ISS)
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