CATH Superfamily 1.10.287.70
The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was: waiting to be named.
FunFam 35: Potassium voltage-gated channel, subfamily H (Eag-...
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 23 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Voltage-gated potassium channel activity GO:0005249
Enables the transmembrane transfer of a potassium ion by a voltage-gated channel. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.
|
6 | A0A0R4IEI6 (/IDA) B3DHL9 (/IDA) F1RBF8 (/IDA) K4EHU2 (/IDA) O18965 (/IDA) Q108P3 (/IDA) |
|
Delayed rectifier potassium channel activity GO:0005251
Enables the transmembrane transfer of a potassium ion by a delayed rectifying voltage-gated channel. A delayed rectifying current-voltage relation is one where channel activation kinetics are time-dependent, and inactivation is slow.
|
6 | O95259 (/IDA) O95259 (/IDA) O95259 (/IDA) O95259 (/IDA) Q60603 (/IDA) Q63472 (/IDA) |
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
5 | O95259 (/IPI) O95259 (/IPI) O95259 (/IPI) O95259 (/IPI) Q63472 (/IPI) |
|
Delayed rectifier potassium channel activity GO:0005251
Enables the transmembrane transfer of a potassium ion by a delayed rectifying voltage-gated channel. A delayed rectifying current-voltage relation is one where channel activation kinetics are time-dependent, and inactivation is slow.
|
4 | O95259 (/TAS) O95259 (/TAS) O95259 (/TAS) O95259 (/TAS) |
|
Phosphatidylinositol bisphosphate binding GO:1902936
Interacting selectively and non-covalently with phosphatidylinositol bisphosphate.
|
4 | O95259 (/IDA) O95259 (/IDA) O95259 (/IDA) O95259 (/IDA) |
|
Delayed rectifier potassium channel activity GO:0005251
Enables the transmembrane transfer of a potassium ion by a delayed rectifying voltage-gated channel. A delayed rectifying current-voltage relation is one where channel activation kinetics are time-dependent, and inactivation is slow.
|
3 | O18965 (/ISS) Q60603 (/ISS) Q63472 (/ISS) |
|
Phosphatidylinositol bisphosphate binding GO:1902936
Interacting selectively and non-covalently with phosphatidylinositol bisphosphate.
|
3 | O18965 (/ISS) Q60603 (/ISS) Q63472 (/ISS) |
|
Ion channel binding GO:0044325
Interacting selectively and non-covalently with one or more specific sites on an ion channel, a protein complex that spans a membrane and forms a water-filled channel across the phospholipid bilayer allowing selective ion transport down its electrochemical gradient.
|
2 | Q63472 (/IPI) Q9EPI9 (/IPI) |
|
Ion channel binding GO:0044325
Interacting selectively and non-covalently with one or more specific sites on an ion channel, a protein complex that spans a membrane and forms a water-filled channel across the phospholipid bilayer allowing selective ion transport down its electrochemical gradient.
|
2 | Q60603 (/ISO) Q920E3 (/ISO) |
|
Protein heterodimerization activity GO:0046982
Interacting selectively and non-covalently with a nonidentical protein to form a heterodimer.
|
2 | Q63472 (/IPI) Q9EPI9 (/IPI) |
|
Protein heterodimerization activity GO:0046982
Interacting selectively and non-covalently with a nonidentical protein to form a heterodimer.
|
2 | Q60603 (/ISO) Q920E3 (/ISO) |
|
Delayed rectifier potassium channel activity GO:0005251
Enables the transmembrane transfer of a potassium ion by a delayed rectifying voltage-gated channel. A delayed rectifying current-voltage relation is one where channel activation kinetics are time-dependent, and inactivation is slow.
|
1 | Q60603 (/ISO) |
|
Calmodulin binding GO:0005516
Interacting selectively and non-covalently with calmodulin, a calcium-binding protein with many roles, both in the calcium-bound and calcium-free states.
|
1 | Q63472 (/IDA) |
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Calmodulin binding GO:0005516
Interacting selectively and non-covalently with calmodulin, a calcium-binding protein with many roles, both in the calcium-bound and calcium-free states.
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1 | Q60603 (/ISO) |
|
Protein kinase binding GO:0019901
Interacting selectively and non-covalently with a protein kinase, any enzyme that catalyzes the transfer of a phosphate group, usually from ATP, to a protein substrate.
|
1 | Q63472 (/IPI) |
|
Protein kinase binding GO:0019901
Interacting selectively and non-covalently with a protein kinase, any enzyme that catalyzes the transfer of a phosphate group, usually from ATP, to a protein substrate.
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1 | Q60603 (/ISO) |
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Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
|
1 | Q63472 (/IDA) |
|
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
|
1 | Q60603 (/ISO) |
|
14-3-3 protein binding GO:0071889
Interacting selectively and non-covalently with a 14-3-3 protein. A 14-3-3 protein is any of a large family of approximately 30kDa acidic proteins which exist primarily as homo- and heterodimers within all eukaryotic cells, and have been implicated in the modulation of distinct biological processes by binding to specific phosphorylated sites on diverse target proteins, thereby forcing conformational changes or influencing interactions between their targets and other molecules. Each 14-3-3 protein sequence can be roughly divided into three sections: a divergent amino terminus, the conserved core region and a divergent carboxy-terminus. The conserved middle core region of the 14-3-3s encodes an amphipathic groove that forms the main functional domain, a cradle for interacting with client proteins.
|
1 | Q63472 (/IPI) |
|
14-3-3 protein binding GO:0071889
Interacting selectively and non-covalently with a 14-3-3 protein. A 14-3-3 protein is any of a large family of approximately 30kDa acidic proteins which exist primarily as homo- and heterodimers within all eukaryotic cells, and have been implicated in the modulation of distinct biological processes by binding to specific phosphorylated sites on diverse target proteins, thereby forcing conformational changes or influencing interactions between their targets and other molecules. Each 14-3-3 protein sequence can be roughly divided into three sections: a divergent amino terminus, the conserved core region and a divergent carboxy-terminus. The conserved middle core region of the 14-3-3s encodes an amphipathic groove that forms the main functional domain, a cradle for interacting with client proteins.
|
1 | Q60603 (/ISO) |
|
Voltage-gated ion channel activity involved in regulation of presynaptic membrane potential GO:0099508
Voltage-gated ion channel activity, occurring in the presynaptic membrane, involved in regulation of presynaptic membrane potential. This is a key step in synaptic transmission, following the arrival of an action potential at the synapse.
|
1 | Q60603 (/IDA) |
|
Voltage-gated ion channel activity involved in regulation of presynaptic membrane potential GO:0099508
Voltage-gated ion channel activity, occurring in the presynaptic membrane, involved in regulation of presynaptic membrane potential. This is a key step in synaptic transmission, following the arrival of an action potential at the synapse.
|
1 | Q60603 (/IMP) |
|
Phosphatidylinositol bisphosphate binding GO:1902936
Interacting selectively and non-covalently with phosphatidylinositol bisphosphate.
|
1 | Q60603 (/ISO) |
There are 31 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Potassium ion transmembrane transport GO:0071805
A process in which a potassium ion is transported from one side of a membrane to the other.
|
6 | O95259 (/IDA) O95259 (/IDA) O95259 (/IDA) O95259 (/IDA) Q60603 (/IDA) Q63472 (/IDA) |
|
Somitogenesis GO:0001756
The formation of mesodermal clusters that are arranged segmentally along the anterior posterior axis of an embryo.
|
5 | A0A0R4IEI6 (/IMP) B3DHL9 (/IMP) F1RBF8 (/IMP) K4EHU2 (/IMP) Q108P3 (/IMP) |
|
Hindbrain formation GO:0021576
The process that gives rise to the hindbrain. This process pertains to the initial formation of a structure from unspecified parts. The hindbrain is the region consisting of the medulla, pons and cerebellum. Areas of the hindbrain control motor and autonomic functions.
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5 | A0A0R4IEI6 (/IMP) B3DHL9 (/IMP) F1RBF8 (/IMP) K4EHU2 (/IMP) Q108P3 (/IMP) |
|
Chordate embryonic development GO:0043009
The process whose specific outcome is the progression of the embryo over time, from zygote formation through a stage including a notochord and neural tube until birth or egg hatching.
|
5 | A0A0R4IEI6 (/IMP) B3DHL9 (/IMP) F1RBF8 (/IMP) K4EHU2 (/IMP) Q108P3 (/IMP) |
|
Potassium ion transport GO:0006813
The directed movement of potassium ions (K+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
|
4 | O95259 (/TAS) O95259 (/TAS) O95259 (/TAS) O95259 (/TAS) |
|
Myoblast fusion GO:0007520
A process in which non-proliferating myoblasts fuse to existing fibers or to myotubes to form new fibers. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers.
|
4 | O95259 (/TAS) O95259 (/TAS) O95259 (/TAS) O95259 (/TAS) |
|
Regulation of cell population proliferation GO:0042127
Any process that modulates the frequency, rate or extent of cell proliferation.
|
4 | O95259 (/IMP) O95259 (/IMP) O95259 (/IMP) O95259 (/IMP) |
|
Phosphatidylinositol-mediated signaling GO:0048015
A series of molecular signals in which a cell uses a phosphatidylinositol-mediated signaling to convert a signal into a response. Phosphatidylinositols include phosphatidylinositol (PtdIns) and its phosphorylated derivatives.
|
4 | O95259 (/IMP) O95259 (/IMP) O95259 (/IMP) O95259 (/IMP) |
|
Cellular response to calcium ion GO:0071277
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a calcium ion stimulus.
|
4 | O95259 (/IMP) O95259 (/IMP) O95259 (/IMP) O95259 (/IMP) |
|
Regulation of G2/M transition of mitotic cell cycle GO:0010389
Any signalling pathway that modulates the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G2 phase to M phase of the mitotic cell cycle.
|
3 | Q8NCM2 (/IDA) Q8NCM2 (/IDA) Q8NCM2 (/IDA) |
|
Regulation of cell population proliferation GO:0042127
Any process that modulates the frequency, rate or extent of cell proliferation.
|
3 | O18965 (/ISS) Q60603 (/ISS) Q63472 (/ISS) |
|
Phosphatidylinositol-mediated signaling GO:0048015
A series of molecular signals in which a cell uses a phosphatidylinositol-mediated signaling to convert a signal into a response. Phosphatidylinositols include phosphatidylinositol (PtdIns) and its phosphorylated derivatives.
|
3 | O18965 (/ISS) Q60603 (/ISS) Q63472 (/ISS) |
|
Potassium ion transmembrane transport GO:0071805
A process in which a potassium ion is transported from one side of a membrane to the other.
|
3 | O18965 (/ISS) Q60603 (/ISS) Q63472 (/ISS) |
|
Cellular response to calcium ion GO:0071277
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a calcium ion stimulus.
|
2 | O18965 (/ISS) Q60603 (/ISS) |
|
Startle response GO:0001964
An action or movement due to the application of a sudden unexpected stimulus.
|
1 | Q63472 (/IMP) |
|
Startle response GO:0001964
An action or movement due to the application of a sudden unexpected stimulus.
|
1 | Q60603 (/ISO) |
|
Regulation of transcription, DNA-templated GO:0006355
Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.
|
1 | B3DHL9 (/IMP) |
|
Mesoderm development GO:0007498
The process whose specific outcome is the progression of the mesoderm over time, from its formation to the mature structure. The mesoderm is the middle germ layer that develops into muscle, bone, cartilage, blood and connective tissue.
|
1 | B3DHL9 (/IMP) |
|
Regulation of G2/M transition of mitotic cell cycle GO:0010389
Any signalling pathway that modulates the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G2 phase to M phase of the mitotic cell cycle.
|
1 | Q920E3 (/ISO) |
|
Ion transmembrane transport GO:0034220
A process in which an ion is transported across a membrane.
|
1 | Q63472 (/IDA) |
|
Ion transmembrane transport GO:0034220
A process in which an ion is transported across a membrane.
|
1 | Q60603 (/ISO) |
|
Regulation of cell population proliferation GO:0042127
Any process that modulates the frequency, rate or extent of cell proliferation.
|
1 | Q60603 (/ISO) |
|
Phosphatidylinositol-mediated signaling GO:0048015
A series of molecular signals in which a cell uses a phosphatidylinositol-mediated signaling to convert a signal into a response. Phosphatidylinositols include phosphatidylinositol (PtdIns) and its phosphorylated derivatives.
|
1 | Q60603 (/ISO) |
|
Cellular response to calcium ion GO:0071277
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a calcium ion stimulus.
|
1 | Q63472 (/IDA) |
|
Cellular response to calcium ion GO:0071277
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a calcium ion stimulus.
|
1 | Q60603 (/ISO) |
|
Potassium ion transmembrane transport GO:0071805
A process in which a potassium ion is transported from one side of a membrane to the other.
|
1 | O18965 (/IMP) |
|
Potassium ion transmembrane transport GO:0071805
A process in which a potassium ion is transported from one side of a membrane to the other.
|
1 | Q60603 (/ISO) |
|
Regulation of presynaptic cytosolic calcium ion concentration GO:0099509
Any process that regulates the concentration of calcium in the presynaptic cytosol.
|
1 | Q60603 (/IDA) |
|
Regulation of presynaptic cytosolic calcium ion concentration GO:0099509
Any process that regulates the concentration of calcium in the presynaptic cytosol.
|
1 | Q60603 (/IMP) |
|
Regulation of synaptic vesicle exocytosis GO:2000300
Any process that modulates the frequency, rate or extent of synaptic vesicle exocytosis.
|
1 | Q60603 (/IDA) |
|
Regulation of synaptic vesicle exocytosis GO:2000300
Any process that modulates the frequency, rate or extent of synaptic vesicle exocytosis.
|
1 | Q60603 (/IMP) |
There are 40 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
7 | O95259 (/TAS) O95259 (/TAS) O95259 (/TAS) O95259 (/TAS) Q8NCM2 (/TAS) Q8NCM2 (/TAS) Q8NCM2 (/TAS) |
|
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
|
6 | O95259 (/IDA) O95259 (/IDA) O95259 (/IDA) O95259 (/IDA) Q60603 (/IDA) Q63472 (/IDA) |
|
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
|
5 | O18965 (/IMP) O95259 (/IMP) O95259 (/IMP) O95259 (/IMP) O95259 (/IMP) |
|
Voltage-gated potassium channel complex GO:0008076
A protein complex that forms a transmembrane channel through which potassium ions may cross a cell membrane in response to changes in membrane potential.
|
4 | O95259 (/IDA) O95259 (/IDA) O95259 (/IDA) O95259 (/IDA) |
|
Voltage-gated potassium channel complex GO:0008076
A protein complex that forms a transmembrane channel through which potassium ions may cross a cell membrane in response to changes in membrane potential.
|
4 | O95259 (/TAS) O95259 (/TAS) O95259 (/TAS) O95259 (/TAS) |
|
Cell surface GO:0009986
The external part of the cell wall and/or plasma membrane.
|
4 | Q63472 (/IDA) Q8NCM2 (/IDA) Q8NCM2 (/IDA) Q8NCM2 (/IDA) |
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Early endosome membrane GO:0031901
The lipid bilayer surrounding an early endosome.
|
4 | O95259 (/IDA) O95259 (/IDA) O95259 (/IDA) O95259 (/IDA) |
|
Intracellular membrane-bounded organelle GO:0043231
Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.
|
4 | O95259 (/IDA) O95259 (/IDA) O95259 (/IDA) O95259 (/IDA) |
|
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
|
3 | O18965 (/ISS) Q60603 (/ISS) Q63472 (/ISS) |
|
Voltage-gated potassium channel complex GO:0008076
A protein complex that forms a transmembrane channel through which potassium ions may cross a cell membrane in response to changes in membrane potential.
|
3 | O18965 (/ISS) Q60603 (/ISS) Q63472 (/ISS) |
|
Early endosome membrane GO:0031901
The lipid bilayer surrounding an early endosome.
|
3 | O18965 (/ISS) Q60603 (/ISS) Q63472 (/ISS) |
|
Cell surface GO:0009986
The external part of the cell wall and/or plasma membrane.
|
2 | Q60603 (/ISO) Q920E3 (/ISO) |
|
Nuclear inner membrane GO:0005637
The inner, i.e. lumen-facing, lipid bilayer of the nuclear envelope.
|
1 | Q63472 (/IDA) |
|
Nuclear inner membrane GO:0005637
The inner, i.e. lumen-facing, lipid bilayer of the nuclear envelope.
|
1 | Q60603 (/ISO) |
|
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
1 | Q63472 (/IDA) |
|
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
1 | Q60603 (/ISO) |
|
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
|
1 | Q60603 (/ISO) |
|
Voltage-gated potassium channel complex GO:0008076
A protein complex that forms a transmembrane channel through which potassium ions may cross a cell membrane in response to changes in membrane potential.
|
1 | Q60603 (/ISO) |
|
Axon GO:0030424
The long process of a neuron that conducts nerve impulses, usually away from the cell body to the terminals and varicosities, which are sites of storage and release of neurotransmitter.
|
1 | Q63472 (/IDA) |
|
Axon GO:0030424
The long process of a neuron that conducts nerve impulses, usually away from the cell body to the terminals and varicosities, which are sites of storage and release of neurotransmitter.
|
1 | Q60603 (/ISO) |
|
Dendrite GO:0030425
A neuron projection that has a short, tapering, morphology. Dendrites receive and integrate signals from other neurons or from sensory stimuli, and conduct nerve impulses towards the axon or the cell body. In most neurons, the impulse is conveyed from dendrites to axon via the cell body, but in some types of unipolar neuron, the impulse does not travel via the cell body.
|
1 | Q63472 (/IDA) |
|
Dendrite GO:0030425
A neuron projection that has a short, tapering, morphology. Dendrites receive and integrate signals from other neurons or from sensory stimuli, and conduct nerve impulses towards the axon or the cell body. In most neurons, the impulse is conveyed from dendrites to axon via the cell body, but in some types of unipolar neuron, the impulse does not travel via the cell body.
|
1 | Q60603 (/ISO) |
|
Axolemma GO:0030673
The portion of the plasma membrane surrounding an axon; it is a specialized trilaminar random mosaic of protein molecules floating within a fluid matrix of highly mobile phospholipid molecules, 7-8 nm in thickness.
|
1 | Q63472 (/IDA) |
|
Axolemma GO:0030673
The portion of the plasma membrane surrounding an axon; it is a specialized trilaminar random mosaic of protein molecules floating within a fluid matrix of highly mobile phospholipid molecules, 7-8 nm in thickness.
|
1 | Q60603 (/ISO) |
|
Early endosome membrane GO:0031901
The lipid bilayer surrounding an early endosome.
|
1 | Q60603 (/ISO) |
|
Potassium channel complex GO:0034705
An ion channel complex through which potassium ions pass.
|
1 | Q63472 (/IDA) |
|
Potassium channel complex GO:0034705
An ion channel complex through which potassium ions pass.
|
1 | Q60603 (/ISO) |
|
Presynaptic membrane GO:0042734
A specialized area of membrane of the axon terminal that faces the plasma membrane of the neuron or muscle fiber with which the axon terminal establishes a synaptic junction; many synaptic junctions exhibit structural presynaptic characteristics, such as conical, electron-dense internal protrusions, that distinguish it from the remainder of the axon plasma membrane.
|
1 | Q63472 (/IDA) |
|
Presynaptic membrane GO:0042734
A specialized area of membrane of the axon terminal that faces the plasma membrane of the neuron or muscle fiber with which the axon terminal establishes a synaptic junction; many synaptic junctions exhibit structural presynaptic characteristics, such as conical, electron-dense internal protrusions, that distinguish it from the remainder of the axon plasma membrane.
|
1 | Q60603 (/ISO) |
|
Neuronal cell body GO:0043025
The portion of a neuron that includes the nucleus, but excludes cell projections such as axons and dendrites.
|
1 | Q63472 (/IDA) |
|
Neuronal cell body GO:0043025
The portion of a neuron that includes the nucleus, but excludes cell projections such as axons and dendrites.
|
1 | Q60603 (/ISO) |
|
Intracellular membrane-bounded organelle GO:0043231
Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.
|
1 | Q60603 (/ISO) |
|
Synapse GO:0045202
The junction between a nerve fiber of one neuron and another neuron, muscle fiber or glial cell. As the nerve fiber approaches the synapse it enlarges into a specialized structure, the presynaptic nerve ending, which contains mitochondria and synaptic vesicles. At the tip of the nerve ending is the presynaptic membrane; facing it, and separated from it by a minute cleft (the synaptic cleft) is a specialized area of membrane on the receiving cell, known as the postsynaptic membrane. In response to the arrival of nerve impulses, the presynaptic nerve ending secretes molecules of neurotransmitters into the synaptic cleft. These diffuse across the cleft and transmit the signal to the postsynaptic membrane.
|
1 | Q63472 (/IDA) |
|
Synapse GO:0045202
The junction between a nerve fiber of one neuron and another neuron, muscle fiber or glial cell. As the nerve fiber approaches the synapse it enlarges into a specialized structure, the presynaptic nerve ending, which contains mitochondria and synaptic vesicles. At the tip of the nerve ending is the presynaptic membrane; facing it, and separated from it by a minute cleft (the synaptic cleft) is a specialized area of membrane on the receiving cell, known as the postsynaptic membrane. In response to the arrival of nerve impulses, the presynaptic nerve ending secretes molecules of neurotransmitters into the synaptic cleft. These diffuse across the cleft and transmit the signal to the postsynaptic membrane.
|
1 | Q60603 (/ISO) |
|
Perinuclear region of cytoplasm GO:0048471
Cytoplasm situated near, or occurring around, the nucleus.
|
1 | Q63472 (/IDA) |
|
Perinuclear region of cytoplasm GO:0048471
Cytoplasm situated near, or occurring around, the nucleus.
|
1 | Q60603 (/ISO) |
|
Parallel fiber to Purkinje cell synapse GO:0098688
An excitatory synapse formed by the parallel fibers of granule cells synapsing onto the dendrites of Purkinje cells.
|
1 | Q60603 (/IDA) |
|
Parallel fiber to Purkinje cell synapse GO:0098688
An excitatory synapse formed by the parallel fibers of granule cells synapsing onto the dendrites of Purkinje cells.
|
1 | Q60603 (/IMP) |
|
Integral component of presynaptic membrane GO:0099056
The component of the presynaptic membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
|
1 | Q63472 (/IDA) |
|
Integral component of presynaptic membrane GO:0099056
The component of the presynaptic membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
|
1 | Q60603 (/ISO) |
