The cell cycle process in which replicated homologous chromosomes are organized and then physically separated and apportioned to two sets during the mitotic cell cycle. Each replicated chromosome, composed of two sister chromatids, aligns at the cell equator, paired with its homologous partner. One homolog of each morphologic type goes into each of the resulting chromosome sets.

A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures.

Any cellular process that depends upon or alters the microtubule cytoskeleton, that part of the cytoskeleton comprising microtubules and their associated proteins.

The directed movement of the nucleus along microtubules within the cell, mediated by motor proteins.

The cell cycle process in which replicated homologous chromosomes are organized and then physically separated and apportioned to two sets during the first division of the meiotic cell cycle. Each replicated chromosome, composed of two sister chromatids, aligns at the cell equator, paired with its homologous partner; this pairing off, referred to as synapsis, permits genetic recombination. One homolog (both sister chromatids) of each morphologic type goes into each of the resulting chromosome sets.

The aggregation, arrangement and bonding together of a set of components to form the spindle that contributes to the process of mitosis.

Any process that activates or increases the frequency, rate or extent of the directed movement of proteins within cells.

A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of structures formed of microtubules and associated proteins in the cytoplasm of a cell.

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a drug stimulus. A drug is a substance used in the diagnosis, treatment or prevention of a disease.

The cell cycle process in which replicated homologous chromosomes are organized and then physically separated and apportioned to two sets during the mitotic cell cycle. Each replicated chromosome, composed of two sister chromatids, aligns at the cell equator, paired with its homologous partner. One homolog of each morphologic type goes into each of the resulting chromosome sets.

Any cellular process that depends upon or alters the microtubule cytoskeleton, that part of the cytoskeleton comprising microtubules and their associated proteins.

The removal of tubulin heterodimers from one or both ends of a microtubule.

Behavior that is dependent upon the sensation of a mechanical stimulus.

Behavior that is dependent upon the sensation of a mechanical stimulus.

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mechanical stimulus.

The directed movement of the nucleus along microtubules within the cell, mediated by motor proteins.

Any process that establishes the spatial arrangement of mitochondria within the cell.

The series of events in which a mechanical stimulus is received and converted into a molecular signal as part of sensory perception.

The series of events involved in the perception of touch in which a mechanical stimulus is received and converted into a molecular signal.

The controlled breakdown of the spindle during a mitotic cell cycle.

Any cellular process that results in the specification, formation or maintenance of a polarized intracellular organization or cell growth patterns that regulate the shape of a cell.

The directed movement of the nucleus by pushing forces exerted by polymerization of backward-extending microtubules.

Any spindle pole body duplication that is involved in the mitotic cell cycle.

Any process that activates or increases the frequency, rate or extent of detection of mechanical stimulus involved in sensory perception of touch.

Any process that activates or increases the frequency, rate or extent of mechanosensory behavior.

Any of the spindle microtubules that attach to the kinetochores of chromosomes by their plus ends, and maneuver the chromosomes during mitotic or meiotic chromosome segregation.

Any microtubule in the nucleus of a cell.

Any microtubule in the cytoplasm of a cell.

A heterodimer of tubulins alpha and beta that constitutes the protomer for microtubule assembly.

A heterodimer of tubulins alpha and beta that constitutes the protomer for microtubule assembly.

Any microtubule that is part of a mitotic or meiotic spindle; anchored at one spindle pole.

The microtubule organizing center in fungi; functionally homologous to the animal cell centrosome.

Any microtubule in the cytoplasm of a cell.

A heterodimer of tubulins alpha and beta that constitutes the protomer for microtubule assembly.

Any of the spindle microtubules that radiate in all directions from the spindle poles and are thought to contribute to the forces that separate the poles and position them in relation to the rest of the cell.

A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.

A prolongation or process extending from a nerve cell, e.g. an axon or dendrite.

The portion of a neuron that includes the nucleus, but excludes cell projections such as axons and dendrites.

A heterodimer of tubulins alpha and beta that constitutes the protomer for microtubule assembly.