CATH Superfamily 1.10.287.4070
The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was: waiting to be named.
FunFam 1: Probable Nucleolar protein 58
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 14 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
RNA binding GO:0003723
Interacting selectively and non-covalently with an RNA molecule or a portion thereof.
|
14 |
Q8IJV7 (/ISS)
Q8IJV7 (/ISS)
Q8IJV7 (/ISS)
Q8IJV7 (/ISS)
Q8IJV7 (/ISS)
Q8IJV7 (/ISS)
Q8IJV7 (/ISS)
Q8IJV7 (/ISS)
Q8IJV7 (/ISS)
Q8IJV7 (/ISS)
(4 more) |
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
7 | Q12499 (/IPI) Q12499 (/IPI) Q12499 (/IPI) Q12499 (/IPI) Q12499 (/IPI) Q9QZ86 (/IPI) Q9Y2X3 (/IPI) |
MRNA binding GO:0003729
Interacting selectively and non-covalently with messenger RNA (mRNA), an intermediate molecule between DNA and protein. mRNA includes UTR and coding sequences, but does not contain introns.
|
5 | Q12499 (/HDA) Q12499 (/HDA) Q12499 (/HDA) Q12499 (/HDA) Q12499 (/HDA) |
SnRNA binding GO:0017069
Interacting selectively and non-covalently with a small nuclear RNA (snRNA).
|
5 | Q12499 (/IDA) Q12499 (/IDA) Q12499 (/IDA) Q12499 (/IDA) Q12499 (/IDA) |
SnoRNA binding GO:0030515
Interacting selectively and non-covalently with small nucleolar RNA.
|
2 | Q38F23 (/ISM) Q9P7S7 (/ISM) |
TFIID-class transcription factor complex binding GO:0001094
Interacting selectively and non-covalently with a general RNA polymerase II transcription factor belonging to the TFIID complex, one of the factors involved in formation of the preinitiation complex (PIC) by RNA polymerase II.
|
1 | Q9Y2X3 (/IPI) |
TFIID-class transcription factor complex binding GO:0001094
Interacting selectively and non-covalently with a general RNA polymerase II transcription factor belonging to the TFIID complex, one of the factors involved in formation of the preinitiation complex (PIC) by RNA polymerase II.
|
1 | Q6DFW4 (/ISO) |
RNA binding GO:0003723
Interacting selectively and non-covalently with an RNA molecule or a portion thereof.
|
1 | Q9Y2X3 (/HDA) |
MRNA binding GO:0003729
Interacting selectively and non-covalently with messenger RNA (mRNA), an intermediate molecule between DNA and protein. mRNA includes UTR and coding sequences, but does not contain introns.
|
1 | Q38F23 (/IDA) |
SnoRNA binding GO:0030515
Interacting selectively and non-covalently with small nucleolar RNA.
|
1 | Q9Y2X3 (/IDA) |
SnoRNA binding GO:0030515
Interacting selectively and non-covalently with small nucleolar RNA.
|
1 | Q6DFW4 (/ISO) |
SnoRNA binding GO:0030515
Interacting selectively and non-covalently with small nucleolar RNA.
|
1 | G4MPA1 (/ISS) |
ATPase binding GO:0051117
Interacting selectively and non-covalently with an ATPase, any enzyme that catalyzes the hydrolysis of ATP.
|
1 | Q9Y2X3 (/IPI) |
ATPase binding GO:0051117
Interacting selectively and non-covalently with an ATPase, any enzyme that catalyzes the hydrolysis of ATP.
|
1 | Q6DFW4 (/ISO) |
There are 15 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
RRNA processing GO:0006364
Any process involved in the conversion of a primary ribosomal RNA (rRNA) transcript into one or more mature rRNA molecules.
|
17 |
G4MPA1 (/ISS)
Q8IJV7 (/ISS)
Q8IJV7 (/ISS)
Q8IJV7 (/ISS)
Q8IJV7 (/ISS)
Q8IJV7 (/ISS)
Q8IJV7 (/ISS)
Q8IJV7 (/ISS)
Q8IJV7 (/ISS)
Q8IJV7 (/ISS)
(7 more) |
Endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) GO:0000447
Endonucleolytic cleavage between the SSU-rRNA and the 5.8S rRNA of an rRNA molecule originally produced as a tricistronic rRNA transcript that contained the Small SubUnit (SSU) rRNA, the 5.8S rRNA, and the Large SubUnit (LSU) rRNA, in that order, from 5' to 3' along the primary transcript.
|
5 | Q12499 (/IMP) Q12499 (/IMP) Q12499 (/IMP) Q12499 (/IMP) Q12499 (/IMP) |
RRNA 2'-O-methylation GO:0000451
The addition of a methyl group to the 2'-oxygen atom of a nucleotide residue in an rRNA molecule during ribosome biogenesis.
|
5 | Q12499 (/TAS) Q12499 (/TAS) Q12499 (/TAS) Q12499 (/TAS) Q12499 (/TAS) |
Endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA) GO:0000472
Endonucleolytic cleavage between the 5'-External Transcribed Spacer (5'-ETS) and the 5' end of the SSU-rRNA of a tricistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, the 5.8S rRNA, and the Large Subunit (LSU) rRNA in that order from 5' to 3' along the primary transcript, to produce the mature end of the SSU-rRNA.
|
5 | Q12499 (/IMP) Q12499 (/IMP) Q12499 (/IMP) Q12499 (/IMP) Q12499 (/IMP) |
Endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) GO:0000480
Endonucleolytic cleavage within the 5'-External Transcribed Spacer (ETS) of a tricistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, the 5.8S rRNA, and the Large Subunit (LSU) rRNA in that order from 5' to 3' along the primary transcript. Endonucleolytic cleavage within the 5'-ETS of the pre-RNA is conserved as one of the early steps of rRNA processing in all eukaryotes, but the specific position of cleavage is variable.
|
5 | Q12499 (/IMP) Q12499 (/IMP) Q12499 (/IMP) Q12499 (/IMP) Q12499 (/IMP) |
RRNA processing GO:0006364
Any process involved in the conversion of a primary ribosomal RNA (rRNA) transcript into one or more mature rRNA molecules.
|
5 | Q12499 (/IDA) Q12499 (/IDA) Q12499 (/IDA) Q12499 (/IDA) Q12499 (/IDA) |
RRNA methylation GO:0031167
The posttranscriptional addition of methyl groups to specific residues in an rRNA molecule.
|
5 | Q12499 (/TAS) Q12499 (/TAS) Q12499 (/TAS) Q12499 (/TAS) Q12499 (/TAS) |
Protein localization to nucleolus GO:1902570
A process in which a protein is transported to, or maintained in, a location within a nucleolus.
|
5 | Q12499 (/IMP) Q12499 (/IMP) Q12499 (/IMP) Q12499 (/IMP) Q12499 (/IMP) |
MRNA splicing, via spliceosome GO:0000398
The joining together of exons from one or more primary transcripts of messenger RNA (mRNA) and the excision of intron sequences, via a spliceosomal mechanism, so that mRNA consisting only of the joined exons is produced.
|
1 | Q38F23 (/ISM) |
RRNA processing GO:0006364
Any process involved in the conversion of a primary ribosomal RNA (rRNA) transcript into one or more mature rRNA molecules.
|
1 | Q9P7S7 (/ISO) |
RRNA processing GO:0006364
Any process involved in the conversion of a primary ribosomal RNA (rRNA) transcript into one or more mature rRNA molecules.
|
1 | Q9Y2X3 (/TAS) |
Filamentous growth GO:0030447
The process in which a multicellular organism, a unicellular organism or a group of unicellular organisms grow in a threadlike, filamentous shape.
|
1 | Q59S06 (/IMP) |
Ribosome biogenesis GO:0042254
A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of ribosome subunits; includes transport to the sites of protein synthesis.
|
1 | G4MPA1 (/ISS) |
SnoRNA localization GO:0048254
Any process in which small nucleolar RNA is transported to, or maintained in, a specific location.
|
1 | Q9Y2X3 (/IMP) |
SnoRNA localization GO:0048254
Any process in which small nucleolar RNA is transported to, or maintained in, a specific location.
|
1 | Q6DFW4 (/ISO) |
There are 30 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Nucleolus GO:0005730
A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome.
|
25 |
O04658 (/IDA)
Q12499 (/IDA)
Q12499 (/IDA)
Q12499 (/IDA)
Q12499 (/IDA)
Q12499 (/IDA)
Q8IJV7 (/IDA)
Q8IJV7 (/IDA)
Q8IJV7 (/IDA)
Q8IJV7 (/IDA)
(15 more) |
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
|
6 | Q12499 (/TAS) Q12499 (/TAS) Q12499 (/TAS) Q12499 (/TAS) Q12499 (/TAS) Q9Y2X3 (/TAS) |
Small-subunit processome GO:0032040
A large ribonucleoprotein complex that is an early preribosomal complex. In S. cerevisiae, it has a size of 80S and consists of the 35S pre-rRNA, early-associating ribosomal proteins most of which are part of the small ribosomal subunit, the U3 snoRNA and associated proteins.
|
6 | Q12499 (/IDA) Q12499 (/IDA) Q12499 (/IDA) Q12499 (/IDA) Q12499 (/IDA) Q59S06 (/IDA) |
90S preribosome GO:0030686
A large ribonucleoprotein complex considered to be the earliest preribosomal complex. In S. cerevisiae, it has a size of 90S and consists of the 35S pre-rRNA, early-associating ribosomal proteins most of which are part of the small ribosomal subunit, the U3 snoRNA and associated proteins.
|
5 | Q12499 (/HDA) Q12499 (/HDA) Q12499 (/HDA) Q12499 (/HDA) Q12499 (/HDA) |
Box C/D snoRNP complex GO:0031428
A ribonucleoprotein complex containing small nucleolar RNA of the box C/D type that can carry out ribose-2'-O-methylation of target RNAs.
|
5 | Q12499 (/IDA) Q12499 (/IDA) Q12499 (/IDA) Q12499 (/IDA) Q12499 (/IDA) |
Box C/D snoRNP complex GO:0031428
A ribonucleoprotein complex containing small nucleolar RNA of the box C/D type that can carry out ribose-2'-O-methylation of target RNAs.
|
5 | Q12499 (/IPI) Q12499 (/IPI) Q12499 (/IPI) Q12499 (/IPI) Q12499 (/IPI) |
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
3 | Q38F23 (/IDA) Q9QZ86 (/IDA) Q9Y2X3 (/IDA) |
Nucleolus GO:0005730
A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome.
|
3 | G4MPA1 (/ISS) Q9U5W4 (/ISS) Q9VM69 (/ISS) |
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
|
2 | Q9MAB3 (/IDA) Q9MAB3 (/IDA) |
Fibrillar center GO:0001650
A structure found most metazoan nucleoli, but not usually found in lower eukaryotes; surrounded by the dense fibrillar component; the zone of transcription from multiple copies of the pre-rRNA genes is in the border region between these two structures.
|
1 | Q9Y2X3 (/IDA) |
Fibrillar center GO:0001650
A structure found most metazoan nucleoli, but not usually found in lower eukaryotes; surrounded by the dense fibrillar component; the zone of transcription from multiple copies of the pre-rRNA genes is in the border region between these two structures.
|
1 | Q6DFW4 (/ISO) |
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
1 | Q9P7S7 (/HDA) |
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
1 | Q6DFW4 (/ISO) |
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
1 | G4MPA1 (/ISS) |
Nucleolus GO:0005730
A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome.
|
1 | Q9P7S7 (/HDA) |
Nucleolus GO:0005730
A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome.
|
1 | Q6DFW4 (/ISO) |
Nucleolus GO:0005730
A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome.
|
1 | Q9Y2X3 (/TAS) |
Small nucleolar ribonucleoprotein complex GO:0005732
A ribonucleoprotein complex that contains an RNA molecule of the small nucleolar RNA (snoRNA) family and associated proteins. Most are involved in a step of processing of rRNA: cleavage, 2'-O-methylation, or pseudouridylation. The majority, though not all, fall into one of two classes, box C/D type or box H/ACA type.
|
1 | Q9Y2X3 (/IDA) |
Small nucleolar ribonucleoprotein complex GO:0005732
A ribonucleoprotein complex that contains an RNA molecule of the small nucleolar RNA (snoRNA) family and associated proteins. Most are involved in a step of processing of rRNA: cleavage, 2'-O-methylation, or pseudouridylation. The majority, though not all, fall into one of two classes, box C/D type or box H/ACA type.
|
1 | Q6DFW4 (/ISO) |
Small nucleolar ribonucleoprotein complex GO:0005732
A ribonucleoprotein complex that contains an RNA molecule of the small nucleolar RNA (snoRNA) family and associated proteins. Most are involved in a step of processing of rRNA: cleavage, 2'-O-methylation, or pseudouridylation. The majority, though not all, fall into one of two classes, box C/D type or box H/ACA type.
|
1 | G4MPA1 (/ISS) |
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
1 | Q9Y2X3 (/IDA) |
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
1 | Q6DFW4 (/ISO) |
Plasmodesma GO:0009506
A fine cytoplasmic channel, found in all higher plants, that connects the cytoplasm of one cell to that of an adjacent cell.
|
1 | O04658 (/IDA) |
Cajal body GO:0015030
A class of nuclear body, first seen after silver staining by Ramon y Cajal in 1903, enriched in small nuclear ribonucleoproteins, and certain general RNA polymerase II transcription factors; ultrastructurally, they appear as a tangle of coiled, electron-dense threads roughly 0.5 micrometers in diameter; involved in aspects of snRNP biogenesis; the protein coilin serves as a marker for Cajal bodies. Some argue that Cajal bodies are the sites for preassembly of transcriptosomes, unitary particles involved in transcription and processing of RNA.
|
1 | Q9Y2X3 (/IDA) |
Cajal body GO:0015030
A class of nuclear body, first seen after silver staining by Ramon y Cajal in 1903, enriched in small nuclear ribonucleoproteins, and certain general RNA polymerase II transcription factors; ultrastructurally, they appear as a tangle of coiled, electron-dense threads roughly 0.5 micrometers in diameter; involved in aspects of snRNP biogenesis; the protein coilin serves as a marker for Cajal bodies. Some argue that Cajal bodies are the sites for preassembly of transcriptosomes, unitary particles involved in transcription and processing of RNA.
|
1 | Q6DFW4 (/ISO) |
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
|
1 | Q9Y2X3 (/HDA) |
Box C/D snoRNP complex GO:0031428
A ribonucleoprotein complex containing small nucleolar RNA of the box C/D type that can carry out ribose-2'-O-methylation of target RNAs.
|
1 | Q9Y2X3 (/NAS) |
Small-subunit processome GO:0032040
A large ribonucleoprotein complex that is an early preribosomal complex. In S. cerevisiae, it has a size of 80S and consists of the 35S pre-rRNA, early-associating ribosomal proteins most of which are part of the small ribosomal subunit, the U3 snoRNA and associated proteins.
|
1 | Q9P7S7 (/ISO) |
Pre-snoRNP complex GO:0070761
A ribonucleoprotein complex that contains a precursor small nucleolar RNA (pre-snoRNA) and associated proteins, and forms during small nucleolar ribonucleoprotein complex (snoRNP) assembly. Pre-snoRNP complexes may contain proteins not found in the corresponding mature snoRNP complexes.
|
1 | Q9Y2X3 (/IDA) |
Pre-snoRNP complex GO:0070761
A ribonucleoprotein complex that contains a precursor small nucleolar RNA (pre-snoRNA) and associated proteins, and forms during small nucleolar ribonucleoprotein complex (snoRNP) assembly. Pre-snoRNP complexes may contain proteins not found in the corresponding mature snoRNP complexes.
|
1 | Q6DFW4 (/ISO) |