CATH Superfamily 1.10.287.2250
The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was: waiting to be named.
FunFam 3: Cathepsin L
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 4 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Cysteine-type endopeptidase inhibitor activity GO:0004869
Stops, prevents or reduces the activity of a cysteine-type endopeptidase, any enzyme that hydrolyzes peptide bonds in polypeptides by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile.
|
7 | A1ZBK7 (/IDA) A1ZBK7 (/IDA) A1ZBK7 (/IDA) Q70SU8 (/IDA) Q70SU8 (/IDA) Q70SU8 (/IDA) Q70SU8 (/IDA) |
Protease binding GO:0002020
Interacting selectively and non-covalently with any protease or peptidase.
|
4 | Q70SU8 (/IDA) Q70SU8 (/IDA) Q70SU8 (/IDA) Q70SU8 (/IDA) |
Cysteine-type endopeptidase inhibitor activity GO:0004869
Stops, prevents or reduces the activity of a cysteine-type endopeptidase, any enzyme that hydrolyzes peptide bonds in polypeptides by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile.
|
1 | P12400 (/TAS) |
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
1 | P12400 (/IPI) |
There are 6 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Short-term memory GO:0007614
The memory process that deals with the storage, retrieval and modification of information received a short time (up to about 30 minutes) ago. This type of memory is typically dependent on direct, transient effects of second messenger activation.
|
3 | A1ZBK7 (/IDA) A1ZBK7 (/IDA) A1ZBK7 (/IDA) |
Long-term memory GO:0007616
The memory process that deals with the storage, retrieval and modification of information a long time (typically weeks, months or years) after receiving that information. This type of memory is typically dependent on gene transcription regulated by second messenger activation.
|
3 | A1ZBK7 (/IMP) A1ZBK7 (/IMP) A1ZBK7 (/IMP) |
Inhibition of cysteine-type endopeptidase activity GO:0097340
Any process that prevents the activation of an inactive cysteine-type endopeptidase.
|
3 | A1ZBK7 (/IDA) A1ZBK7 (/IDA) A1ZBK7 (/IDA) |
Negative regulation of protein processing GO:0010955
Any process that decreases the rate, frequency or extent of protein maturation by peptide bond cleavage.
|
1 | P12399 (/IMP) |
Regulation of regulatory T cell differentiation GO:0045589
Any process that modulates the frequency, rate or extent of differentiation of regulatory T cells.
|
1 | P12399 (/IMP) |
Negative regulation of inflammatory response GO:0050728
Any process that stops, prevents, or reduces the frequency, rate or extent of the inflammatory response.
|
1 | P12399 (/IDA) |
There are 8 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Extracellular space GO:0005615
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
|
4 | Q70SU8 (/IDA) Q70SU8 (/IDA) Q70SU8 (/IDA) Q70SU8 (/IDA) |
Cell GO:0005623
The basic structural and functional unit of all organisms. Includes the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.
|
4 | Q70SU8 (/IDA) Q70SU8 (/IDA) Q70SU8 (/IDA) Q70SU8 (/IDA) |
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
4 | Q70SU8 (/IDA) Q70SU8 (/IDA) Q70SU8 (/IDA) Q70SU8 (/IDA) |
Vacuole GO:0005773
A closed structure, found only in eukaryotic cells, that is completely surrounded by unit membrane and contains liquid material. Cells contain one or several vacuoles, that may have different functions from each other. Vacuoles have a diverse array of functions. They can act as a storage organelle for nutrients or waste products, as a degradative compartment, as a cost-effective way of increasing cell size, and as a homeostatic regulator controlling both turgor pressure and pH of the cytosol.
|
4 | Q70SU8 (/IDA) Q70SU8 (/IDA) Q70SU8 (/IDA) Q70SU8 (/IDA) |
Lysosome GO:0005764
A small lytic vacuole that has cell cycle-independent morphology and is found in most animal cells and that contains a variety of hydrolases, most of which have their maximal activities in the pH range 5-6. The contained enzymes display latency if properly isolated. About 40 different lysosomal hydrolases are known and lysosomes have a great variety of morphologies and functions.
|
3 | A1ZBK7 (/ISM) A1ZBK7 (/ISM) A1ZBK7 (/ISM) |
Endomembrane system GO:0012505
A collection of membranous structures involved in transport within the cell. The main components of the endomembrane system are endoplasmic reticulum, Golgi bodies, vesicles, cell membrane and nuclear envelope. Members of the endomembrane system pass materials through each other or though the use of vesicles.
|
3 | A1ZBK7 (/HDA) A1ZBK7 (/HDA) A1ZBK7 (/HDA) |
Lysosome GO:0005764
A small lytic vacuole that has cell cycle-independent morphology and is found in most animal cells and that contains a variety of hydrolases, most of which have their maximal activities in the pH range 5-6. The contained enzymes display latency if properly isolated. About 40 different lysosomal hydrolases are known and lysosomes have a great variety of morphologies and functions.
|
1 | Q9QZE3 (/NAS) |
Dendrite GO:0030425
A neuron projection that has a short, tapering, morphology. Dendrites receive and integrate signals from other neurons or from sensory stimuli, and conduct nerve impulses towards the axon or the cell body. In most neurons, the impulse is conveyed from dendrites to axon via the cell body, but in some types of unipolar neuron, the impulse does not travel via the cell body.
|
1 | P12399 (/IDA) |