The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:
"TPP helical domain
".
FunFam 4: 2-oxoglutarate dehydrogenase E1 component
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 6 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Magnesium ion binding GO:0000287
Interacting selectively and non-covalently with magnesium (Mg) ions.
|
126 |
P0AFG3 (/IDA)
P0AFG3 (/IDA)
P0AFG3 (/IDA)
P0AFG3 (/IDA)
P0AFG3 (/IDA)
P0AFG3 (/IDA)
P0AFG3 (/IDA)
P0AFG3 (/IDA)
P0AFG3 (/IDA)
P0AFG3 (/IDA)
(116 more) |
|
Oxoglutarate dehydrogenase (succinyl-transferring) activity GO:0004591
Catalysis of the reaction: 2-oxoglutarate + lipoamide = S-succinyldihydrolipoamide + CO2.
|
126 |
P0AFG3 (/IDA)
P0AFG3 (/IDA)
P0AFG3 (/IDA)
P0AFG3 (/IDA)
P0AFG3 (/IDA)
P0AFG3 (/IDA)
P0AFG3 (/IDA)
P0AFG3 (/IDA)
P0AFG3 (/IDA)
P0AFG3 (/IDA)
(116 more) |
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
126 |
P0AFG3 (/IPI)
P0AFG3 (/IPI)
P0AFG3 (/IPI)
P0AFG3 (/IPI)
P0AFG3 (/IPI)
P0AFG3 (/IPI)
P0AFG3 (/IPI)
P0AFG3 (/IPI)
P0AFG3 (/IPI)
P0AFG3 (/IPI)
(116 more) |
|
Thiamine pyrophosphate binding GO:0030976
Interacting selectively and non-covalently with thiamine pyrophosphate, the diphosphoric ester of thiamine. Acts as a coenzyme of several (de)carboxylases, transketolases, and alpha-oxoacid dehydrogenases.
|
126 |
P0AFG3 (/IDA)
P0AFG3 (/IDA)
P0AFG3 (/IDA)
P0AFG3 (/IDA)
P0AFG3 (/IDA)
P0AFG3 (/IDA)
P0AFG3 (/IDA)
P0AFG3 (/IDA)
P0AFG3 (/IDA)
P0AFG3 (/IDA)
(116 more) |
|
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
|
126 |
P0AFG3 (/IPI)
P0AFG3 (/IPI)
P0AFG3 (/IPI)
P0AFG3 (/IPI)
P0AFG3 (/IPI)
P0AFG3 (/IPI)
P0AFG3 (/IPI)
P0AFG3 (/IPI)
P0AFG3 (/IPI)
P0AFG3 (/IPI)
(116 more) |
|
Oxoglutarate dehydrogenase (succinyl-transferring) activity GO:0004591
Catalysis of the reaction: 2-oxoglutarate + lipoamide = S-succinyldihydrolipoamide + CO2.
|
8 | Q9KQB3 (/ISS) Q9KQB3 (/ISS) Q9KQB3 (/ISS) Q9KQB3 (/ISS) Q9KQB3 (/ISS) Q9KQB3 (/ISS) Q9KQB3 (/ISS) Q9KQB3 (/ISS) |
There are 1 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Tricarboxylic acid cycle GO:0006099
A nearly universal metabolic pathway in which the acetyl group of acetyl coenzyme A is effectively oxidized to two CO2 and four pairs of electrons are transferred to coenzymes. The acetyl group combines with oxaloacetate to form citrate, which undergoes successive transformations to isocitrate, 2-oxoglutarate, succinyl-CoA, succinate, fumarate, malate, and oxaloacetate again, thus completing the cycle. In eukaryotes the tricarboxylic acid is confined to the mitochondria. See also glyoxylate cycle.
|
8 | Q9KQB3 (/ISS) Q9KQB3 (/ISS) Q9KQB3 (/ISS) Q9KQB3 (/ISS) Q9KQB3 (/ISS) Q9KQB3 (/ISS) Q9KQB3 (/ISS) Q9KQB3 (/ISS) |
There are 2 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
126 |
P0AFG3 (/HDA)
P0AFG3 (/HDA)
P0AFG3 (/HDA)
P0AFG3 (/HDA)
P0AFG3 (/HDA)
P0AFG3 (/HDA)
P0AFG3 (/HDA)
P0AFG3 (/HDA)
P0AFG3 (/HDA)
P0AFG3 (/HDA)
(116 more) |
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
126 |
P0AFG3 (/IDA)
P0AFG3 (/IDA)
P0AFG3 (/IDA)
P0AFG3 (/IDA)
P0AFG3 (/IDA)
P0AFG3 (/IDA)
P0AFG3 (/IDA)
P0AFG3 (/IDA)
P0AFG3 (/IDA)
P0AFG3 (/IDA)
(116 more) |
