The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:

"
CytochromE C oxidase copper chaperone
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 1: cytochrome c oxidase copper chaperone

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 10 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Copper chaperone activity GO:0016531
Directly binding to and delivering copper ions to a target protein.
19 P56394 (/ISS) P56394 (/ISS) P56394 (/ISS) Q14061 (/ISS) Q14061 (/ISS) Q14061 (/ISS) Q14061 (/ISS) Q14061 (/ISS) Q14061 (/ISS) Q14061 (/ISS)
(9 more)
Copper ion binding GO:0005507
Interacting selectively and non-covalently with copper (Cu) ions.
10 Q14061 (/TAS) Q14061 (/TAS) Q14061 (/TAS) Q14061 (/TAS) Q14061 (/TAS) Q14061 (/TAS) Q14061 (/TAS) Q14061 (/TAS) Q14061 (/TAS) Q14061 (/TAS)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
10 Q14061 (/IPI) Q14061 (/IPI) Q14061 (/IPI) Q14061 (/IPI) Q14061 (/IPI) Q14061 (/IPI) Q14061 (/IPI) Q14061 (/IPI) Q14061 (/IPI) Q14061 (/IPI)
Copper chaperone activity GO:0016531
Directly binding to and delivering copper ions to a target protein.
10 Q14061 (/IMP) Q14061 (/IMP) Q14061 (/IMP) Q14061 (/IMP) Q14061 (/IMP) Q14061 (/IMP) Q14061 (/IMP) Q14061 (/IMP) Q14061 (/IMP) Q14061 (/IMP)
Cuprous ion binding GO:1903136
Interacting selectively and non-covalently with cuprous ion, copper(1+).
10 Q14061 (/IDA) Q14061 (/IDA) Q14061 (/IDA) Q14061 (/IDA) Q14061 (/IDA) Q14061 (/IDA) Q14061 (/IDA) Q14061 (/IDA) Q14061 (/IDA) Q14061 (/IDA)
Copper ion binding GO:0005507
Interacting selectively and non-covalently with copper (Cu) ions.
3 P56394 (/IDA) P56394 (/IDA) P56394 (/IDA)
Enzyme activator activity GO:0008047
Binds to and increases the activity of an enzyme.
3 P56394 (/IMP) P56394 (/IMP) P56394 (/IMP)
Copper chaperone activity GO:0016531
Directly binding to and delivering copper ions to a target protein.
3 P56394 (/ISO) P56394 (/ISO) P56394 (/ISO)
Cuprous ion binding GO:1903136
Interacting selectively and non-covalently with cuprous ion, copper(1+).
3 P56394 (/ISO) P56394 (/ISO) P56394 (/ISO)
Copper chaperone activity GO:0016531
Directly binding to and delivering copper ions to a target protein.
1 P81045 (/IDA)

There are 12 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Generation of precursor metabolites and energy GO:0006091
The chemical reactions and pathways resulting in the formation of precursor metabolites, substances from which energy is derived, and any process involved in the liberation of energy from these substances.
10 Q14061 (/TAS) Q14061 (/TAS) Q14061 (/TAS) Q14061 (/TAS) Q14061 (/TAS) Q14061 (/TAS) Q14061 (/TAS) Q14061 (/TAS) Q14061 (/TAS) Q14061 (/TAS)
Copper ion transport GO:0006825
The directed movement of copper (Cu) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
10 Q14061 (/TAS) Q14061 (/TAS) Q14061 (/TAS) Q14061 (/TAS) Q14061 (/TAS) Q14061 (/TAS) Q14061 (/TAS) Q14061 (/TAS) Q14061 (/TAS) Q14061 (/TAS)
Positive regulation of cell population proliferation GO:0008284
Any process that activates or increases the rate or extent of cell proliferation.
10 Q14061 (/IMP) Q14061 (/IMP) Q14061 (/IMP) Q14061 (/IMP) Q14061 (/IMP) Q14061 (/IMP) Q14061 (/IMP) Q14061 (/IMP) Q14061 (/IMP) Q14061 (/IMP)
Mitochondrial respiratory chain complex IV assembly GO:0033617
The aggregation, arrangement and bonding together of a set of components to form respiratory chain complex IV (also known as cytochrome c oxidase) in the mitochondrial inner membrane.
10 Q14061 (/IMP) Q14061 (/IMP) Q14061 (/IMP) Q14061 (/IMP) Q14061 (/IMP) Q14061 (/IMP) Q14061 (/IMP) Q14061 (/IMP) Q14061 (/IMP) Q14061 (/IMP)
Positive regulation of cytochrome-c oxidase activity GO:1904960
Any process that activates or increases the frequency, rate or extent of cytochrome-c oxidase activity.
10 Q14061 (/IMP) Q14061 (/IMP) Q14061 (/IMP) Q14061 (/IMP) Q14061 (/IMP) Q14061 (/IMP) Q14061 (/IMP) Q14061 (/IMP) Q14061 (/IMP) Q14061 (/IMP)
Brain development GO:0007420
The process whose specific outcome is the progression of the brain over time, from its formation to the mature structure. Brain development begins with patterning events in the neural tube and ends with the mature structure that is the center of thought and emotion. The brain is responsible for the coordination and control of bodily activities and the interpretation of information from the senses (sight, hearing, smell, etc.).
3 Q76MV3 (/IEP) Q76MV3 (/IEP) Q76MV3 (/IEP)
Heart development GO:0007507
The process whose specific outcome is the progression of the heart over time, from its formation to the mature structure. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood.
3 Q76MV3 (/IEP) Q76MV3 (/IEP) Q76MV3 (/IEP)
Positive regulation of cell population proliferation GO:0008284
Any process that activates or increases the rate or extent of cell proliferation.
3 P56394 (/ISO) P56394 (/ISO) P56394 (/ISO)
Mitochondrial respiratory chain complex IV assembly GO:0033617
The aggregation, arrangement and bonding together of a set of components to form respiratory chain complex IV (also known as cytochrome c oxidase) in the mitochondrial inner membrane.
3 P56394 (/ISO) P56394 (/ISO) P56394 (/ISO)
Positive regulation of cytochrome-c oxidase activity GO:1904960
Any process that activates or increases the frequency, rate or extent of cytochrome-c oxidase activity.
3 P56394 (/ISO) P56394 (/ISO) P56394 (/ISO)
Respiratory chain complex IV assembly GO:0008535
The aggregation, arrangement and bonding together of a set of components to form respiratory chain complex IV (also known as cytochrome c oxidase), the terminal member of the respiratory chain of the mitochondrion and some aerobic bacteria. Cytochrome c oxidases are multi-subunit enzymes containing from 13 subunits in the mammalian mitochondrial form to 3-4 subunits in the bacterial forms.
1 Q9VXY5 (/ISS)
Response to copper ion GO:0046688
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a copper ion stimulus.
1 Q66I53 (/IDA)

There are 7 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
10 Q14061 (/IDA) Q14061 (/IDA) Q14061 (/IDA) Q14061 (/IDA) Q14061 (/IDA) Q14061 (/IDA) Q14061 (/IDA) Q14061 (/IDA) Q14061 (/IDA) Q14061 (/IDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
10 Q14061 (/TAS) Q14061 (/TAS) Q14061 (/TAS) Q14061 (/TAS) Q14061 (/TAS) Q14061 (/TAS) Q14061 (/TAS) Q14061 (/TAS) Q14061 (/TAS) Q14061 (/TAS)
Mitochondrial intermembrane space GO:0005758
The region between the inner and outer lipid bilayers of the mitochondrial envelope.
10 Q14061 (/IDA) Q14061 (/IDA) Q14061 (/IDA) Q14061 (/IDA) Q14061 (/IDA) Q14061 (/IDA) Q14061 (/IDA) Q14061 (/IDA) Q14061 (/IDA) Q14061 (/IDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
3 P56394 (/ISO) P56394 (/ISO) P56394 (/ISO)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
3 P56394 (/HDA) P56394 (/HDA) P56394 (/HDA)
Mitochondrial intermembrane space GO:0005758
The region between the inner and outer lipid bilayers of the mitochondrial envelope.
3 P56394 (/ISO) P56394 (/ISO) P56394 (/ISO)
Mitochondrial intermembrane space GO:0005758
The region between the inner and outer lipid bilayers of the mitochondrial envelope.
1 Q9VXY5 (/ISS)
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