The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:

"
ESAT-6-like
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 12: Vacuolar sorting protein SNF7

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 2 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
9 P39929 (/IPI) P39929 (/IPI) P39929 (/IPI) P39929 (/IPI) P39929 (/IPI) P39929 (/IPI) P39929 (/IPI) P39929 (/IPI) P39929 (/IPI)
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
9 P39929 (/IPI) P39929 (/IPI) P39929 (/IPI) P39929 (/IPI) P39929 (/IPI) P39929 (/IPI) P39929 (/IPI) P39929 (/IPI) P39929 (/IPI)

There are 18 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Late endosome to vacuole transport GO:0045324
The directed movement of substances from late endosomes to the vacuole. In yeast, after transport to the prevacuolar compartment, endocytic content is delivered to the late endosome and on to the vacuole. This pathway is analogous to endosome to lysosome transport.
11 P39929 (/IMP) P39929 (/IMP) P39929 (/IMP) P39929 (/IMP) P39929 (/IMP) P39929 (/IMP) P39929 (/IMP) P39929 (/IMP) P39929 (/IMP) Q5ABD0 (/IMP)
(1 more)
Ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway GO:0043162
The chemical reactions and pathways resulting in the breakdown of a protein or peptide covalently tagged with ubiquitin, via the multivesicular body (MVB) sorting pathway; ubiquitin-tagged proteins are sorted into MVBs, and delivered to a lysosome/vacuole for degradation.
9 P39929 (/IC) P39929 (/IC) P39929 (/IC) P39929 (/IC) P39929 (/IC) P39929 (/IC) P39929 (/IC) P39929 (/IC) P39929 (/IC)
Intralumenal vesicle formation GO:0070676
The invagination of the endosome membrane and resulting formation of a vesicle within the lumen of the endosome.
9 P39929 (/IMP) P39929 (/IMP) P39929 (/IMP) P39929 (/IMP) P39929 (/IMP) P39929 (/IMP) P39929 (/IMP) P39929 (/IMP) P39929 (/IMP)
Cellular response to anoxia GO:0071454
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating a decline in oxygen levels to trace amounts, <0.1%.
9 P39929 (/IMP) P39929 (/IMP) P39929 (/IMP) P39929 (/IMP) P39929 (/IMP) P39929 (/IMP) P39929 (/IMP) P39929 (/IMP) P39929 (/IMP)
ATP export GO:1904669
The directed movement of ATP out of a cell or organelle.
9 P39929 (/IMP) P39929 (/IMP) P39929 (/IMP) P39929 (/IMP) P39929 (/IMP) P39929 (/IMP) P39929 (/IMP) P39929 (/IMP) P39929 (/IMP)
Protein targeting to vacuole GO:0006623
The process of directing proteins towards the vacuole, usually using signals contained within the protein.
2 Q5ABD0 (/IMP) Q5ABD0 (/IMP)
Pathogenesis GO:0009405
The set of specific processes that generate the ability of an organism to induce an abnormal, generally detrimental state in another organism.
2 Q5ABD0 (/IMP) Q5ABD0 (/IMP)
Protein processing GO:0016485
Any protein maturation process achieved by the cleavage of a peptide bond or bonds within a protein. Protein maturation is the process leading to the attainment of the full functional capacity of a protein.
2 Q5ABD0 (/IMP) Q5ABD0 (/IMP)
Filamentous growth GO:0030447
The process in which a multicellular organism, a unicellular organism or a group of unicellular organisms grow in a threadlike, filamentous shape.
2 Q5ABD0 (/IMP) Q5ABD0 (/IMP)
Fungal-type cell wall organization GO:0031505
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the fungal-type cell wall.
2 Q5ABD0 (/IMP) Q5ABD0 (/IMP)
Cellular response to drug GO:0035690
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a drug stimulus. A drug is a substance used in the diagnosis, treatment or prevention of a disease.
2 Q5ABD0 (/IMP) Q5ABD0 (/IMP)
Filamentous growth of a population of unicellular organisms in response to pH GO:0036177
The process in which a group of unicellular organisms grow in a threadlike, filamentous shape in response to a pH stimulus. pH is a measure of the acidity or basicity of an aqueous solution.
2 Q5ABD0 (/IMP) Q5ABD0 (/IMP)
Filamentous growth of a population of unicellular organisms in response to neutral pH GO:0036178
The process in which a group of unicellular organisms grow in a threadlike, filamentous shape in response to a neutral pH (pH close to 7) stimulus.
2 Q5ABD0 (/IMP) Q5ABD0 (/IMP)
Filamentous growth of a population of unicellular organisms GO:0044182
The process in which a group of unicellular organisms grow in a threadlike, filamentous shape.
2 Q5ABD0 (/IMP) Q5ABD0 (/IMP)
Cellular response to lithium ion GO:0071285
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lithium (Li+) ion stimulus.
2 Q5ABD0 (/IMP) Q5ABD0 (/IMP)
Cellular response to pH GO:0071467
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pH stimulus. pH is a measure of the acidity or basicity of an aqueous solution.
2 Q5ABD0 (/IMP) Q5ABD0 (/IMP)
Intracellular protein transport GO:0006886
The directed movement of proteins in a cell, including the movement of proteins between specific compartments or structures within a cell, such as organelles of a eukaryotic cell.
1 O74422 (/IC)
Late endosome to vacuole transport via multivesicular body sorting pathway GO:0032511
The directed movement of substances from endosomes to vacuoles by a pathway in which molecules are sorted into multivesicular bodies, which then fuse with the vacuole.
1 O74422 (/ISO)

There are 5 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
ESCRT III complex GO:0000815
An endosomal sorting complex required for transport. Consists of two soluble subcomplexes of highly charged coiled-coil proteins and is required for sorting and/or concentration of multivesicular body (MVB) cargoes.
11 P39929 (/IDA) P39929 (/IDA) P39929 (/IDA) P39929 (/IDA) P39929 (/IDA) P39929 (/IDA) P39929 (/IDA) P39929 (/IDA) P39929 (/IDA) Q5ABD0 (/IDA)
(1 more)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
9 P39929 (/IDA) P39929 (/IDA) P39929 (/IDA) P39929 (/IDA) P39929 (/IDA) P39929 (/IDA) P39929 (/IDA) P39929 (/IDA) P39929 (/IDA)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
9 P39929 (/IDA) P39929 (/IDA) P39929 (/IDA) P39929 (/IDA) P39929 (/IDA) P39929 (/IDA) P39929 (/IDA) P39929 (/IDA) P39929 (/IDA)
ESCRT III complex GO:0000815
An endosomal sorting complex required for transport. Consists of two soluble subcomplexes of highly charged coiled-coil proteins and is required for sorting and/or concentration of multivesicular body (MVB) cargoes.
2 Q5ABD0 (/ISS) Q5ABD0 (/ISS)
Fungal-type vacuole membrane GO:0000329
The lipid bilayer surrounding a vacuole, the shape of which correlates with cell cycle phase. The membrane separates its contents from the cytoplasm of the cell. An example of this structure is found in Saccharomyces cerevisiae.
1 O74422 (/ISO)
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