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CATH Superfamily 1.10.275.10

Fumarase/aspartase (N-terminal domain)

The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:

"
Fumarase/aspartase (N-terminal domain)
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 7: Histidine ammonia-lyase

There are 1 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Histidine ammonia-lyase. [EC: 4.3.1.3]
L-histidine = urocanate + NH(3).
  • Member of the aromatic amino acid lyase family, other members of which are EC 4.3.1.23, EC 4.3.1.24 and EC 4.3.1.25.
  • Catalyzes the first step in the degradation of histidine and the product, urocanic acid, is further metabolized to glutamate.
 7 A7YWP4 B2RXW1 B2RXW1 P21213 P35492 P35492 P42357
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