The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:

"
EF-hand
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 193: EF-hand calcium-binding domain-containing protein ...

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 1 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
1 Q8VDY4 (/IPI)

There are 6 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Positive regulation of protein import into nucleus GO:0042307
Any process that activates or increases the frequency, rate or extent of movement of proteins from the cytoplasm into the nucleus.
1 Q8VDY4 (/IMP)
Positive regulation of protein import into nucleus GO:0042307
Any process that activates or increases the frequency, rate or extent of movement of proteins from the cytoplasm into the nucleus.
1 A8K855 (/ISS)
Positive regulation of transcription by RNA polymerase II GO:0045944
Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
1 Q8VDY4 (/IMP)
Positive regulation of transcription by RNA polymerase II GO:0045944
Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
1 A8K855 (/ISS)
Positive regulation of protein localization to ciliary membrane GO:1903569
Any process that activates or increases the frequency, rate or extent of protein localization to ciliary membrane.
1 Q8VDY4 (/IMP)
Positive regulation of protein localization to ciliary membrane GO:1903569
Any process that activates or increases the frequency, rate or extent of protein localization to ciliary membrane.
1 A8K855 (/ISS)

There are 7 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Ciliary membrane GO:0060170
The portion of the plasma membrane surrounding a cilium.
2 A8K855 (/ISS) Q6DCF6 (/ISS)
Cilium GO:0005929
A specialized eukaryotic organelle that consists of a filiform extrusion of the cell surface and of some cytoplasmic parts. Each cilium is largely bounded by an extrusion of the cytoplasmic (plasma) membrane, and contains a regular longitudinal array of microtubules, anchored to a basal body.
1 A8K855 (/TAS)
Extrinsic component of membrane GO:0019898
The component of a membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.
1 Q8VDY4 (/IDA)
Extrinsic component of membrane GO:0019898
The component of a membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.
1 A8K855 (/ISS)
Ciliary membrane GO:0060170
The portion of the plasma membrane surrounding a cilium.
1 Q8VDY4 (/IDA)
Plasma membrane protein complex GO:0098797
Any protein complex that is part of the plasma membrane.
1 Q8VDY4 (/IDA)
Plasma membrane protein complex GO:0098797
Any protein complex that is part of the plasma membrane.
1 A8K855 (/ISS)
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