The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:
"EF-hand
".
FunFam 187: Programmed cell death protein 6
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 25 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Calcium ion binding GO:0005509
Interacting selectively and non-covalently with calcium ions (Ca2+).
|
9 | G3V7W1 (/ISS) O75340 (/ISS) O75340 (/ISS) O75340 (/ISS) O75340 (/ISS) O75340 (/ISS) O75340 (/ISS) O75340 (/ISS) P12815 (/ISS) |
Magnesium ion binding GO:0000287
Interacting selectively and non-covalently with magnesium (Mg) ions.
|
8 | G3V7W1 (/ISS) O75340 (/ISS) O75340 (/ISS) O75340 (/ISS) O75340 (/ISS) O75340 (/ISS) O75340 (/ISS) O75340 (/ISS) |
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
8 | O75340 (/IPI) O75340 (/IPI) O75340 (/IPI) O75340 (/IPI) O75340 (/IPI) O75340 (/IPI) O75340 (/IPI) P12815 (/IPI) |
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
|
8 | O75340 (/IDA) O75340 (/IDA) O75340 (/IDA) O75340 (/IDA) O75340 (/IDA) O75340 (/IDA) O75340 (/IDA) P12815 (/IDA) |
Protein dimerization activity GO:0046983
The formation of a protein dimer, a macromolecular structure consists of two noncovalently associated identical or nonidentical subunits.
|
8 | O75340 (/IPI) O75340 (/IPI) O75340 (/IPI) O75340 (/IPI) O75340 (/IPI) O75340 (/IPI) O75340 (/IPI) P12815 (/IPI) |
Calcium-dependent protein binding GO:0048306
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules), in the presence of calcium.
|
8 | O75340 (/IPI) O75340 (/IPI) O75340 (/IPI) O75340 (/IPI) O75340 (/IPI) O75340 (/IPI) O75340 (/IPI) P12815 (/IPI) |
Calcium ion binding GO:0005509
Interacting selectively and non-covalently with calcium ions (Ca2+).
|
7 | O75340 (/IDA) O75340 (/IDA) O75340 (/IDA) O75340 (/IDA) O75340 (/IDA) O75340 (/IDA) O75340 (/IDA) |
Protein binding, bridging GO:0030674
The binding activity of a molecule that brings together two or more protein molecules, or a protein and another macromolecule or complex, through a selective, non-covalent, often stoichiometric interaction, permitting those molecules to function in a coordinated way.
|
7 | O75340 (/IMP) O75340 (/IMP) O75340 (/IMP) O75340 (/IMP) O75340 (/IMP) O75340 (/IMP) O75340 (/IMP) |
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
|
7 | O75340 (/IPI) O75340 (/IPI) O75340 (/IPI) O75340 (/IPI) O75340 (/IPI) O75340 (/IPI) O75340 (/IPI) |
Protein membrane anchor GO:0043495
Interacting selectively and non-covalently with both a protein or protein complex and a membrane, in order to maintain the localization of the protein at a specific membrane location.
|
7 | O75340 (/IMP) O75340 (/IMP) O75340 (/IMP) O75340 (/IMP) O75340 (/IMP) O75340 (/IMP) O75340 (/IMP) |
Molecular adaptor activity GO:0060090
The binding activity of a molecule that brings together two or more molecules through a selective, non-covalent, often stoichiometric interaction, permitting those molecules to function in a coordinated way.
|
7 | O75340 (/IMP) O75340 (/IMP) O75340 (/IMP) O75340 (/IMP) O75340 (/IMP) O75340 (/IMP) O75340 (/IMP) |
Magnesium ion binding GO:0000287
Interacting selectively and non-covalently with magnesium (Mg) ions.
|
1 | P12815 (/IDA) |
Calcium ion binding GO:0005509
Interacting selectively and non-covalently with calcium ions (Ca2+).
|
1 | P12815 (/IMP) |
Calcium ion binding GO:0005509
Interacting selectively and non-covalently with calcium ions (Ca2+).
|
1 | P12815 (/ISO) |
Protein binding, bridging GO:0030674
The binding activity of a molecule that brings together two or more protein molecules, or a protein and another macromolecule or complex, through a selective, non-covalent, often stoichiometric interaction, permitting those molecules to function in a coordinated way.
|
1 | P12815 (/ISO) |
Protein binding, bridging GO:0030674
The binding activity of a molecule that brings together two or more protein molecules, or a protein and another macromolecule or complex, through a selective, non-covalent, often stoichiometric interaction, permitting those molecules to function in a coordinated way.
|
1 | P12815 (/ISS) |
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
|
1 | P12815 (/ISO) |
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
|
1 | P12815 (/IPI) |
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
|
1 | P12815 (/ISO) |
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
|
1 | G3V7W1 (/ISS) |
Protein membrane anchor GO:0043495
Interacting selectively and non-covalently with both a protein or protein complex and a membrane, in order to maintain the localization of the protein at a specific membrane location.
|
1 | P12815 (/ISO) |
Protein dimerization activity GO:0046983
The formation of a protein dimer, a macromolecular structure consists of two noncovalently associated identical or nonidentical subunits.
|
1 | P12815 (/ISO) |
Calcium-dependent protein binding GO:0048306
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules), in the presence of calcium.
|
1 | P12815 (/ISO) |
Molecular adaptor activity GO:0060090
The binding activity of a molecule that brings together two or more molecules through a selective, non-covalent, often stoichiometric interaction, permitting those molecules to function in a coordinated way.
|
1 | P12815 (/ISO) |
Molecular adaptor activity GO:0060090
The binding activity of a molecule that brings together two or more molecules through a selective, non-covalent, often stoichiometric interaction, permitting those molecules to function in a coordinated way.
|
1 | G3V7W1 (/ISS) |
There are 50 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Positive regulation of endothelial cell proliferation GO:0001938
Any process that activates or increases the rate or extent of endothelial cell proliferation.
|
7 | O75340 (/IDA) O75340 (/IDA) O75340 (/IDA) O75340 (/IDA) O75340 (/IDA) O75340 (/IDA) O75340 (/IDA) |
Intracellular protein transport GO:0006886
The directed movement of proteins in a cell, including the movement of proteins between specific compartments or structures within a cell, such as organelles of a eukaryotic cell.
|
7 | O75340 (/IDA) O75340 (/IDA) O75340 (/IDA) O75340 (/IDA) O75340 (/IDA) O75340 (/IDA) O75340 (/IDA) |
Endoplasmic reticulum to Golgi vesicle-mediated transport GO:0006888
The directed movement of substances from the endoplasmic reticulum (ER) to the Golgi, mediated by COP II vesicles. Small COP II coated vesicles form from the ER and then fuse directly with the cis-Golgi. Larger structures are transported along microtubules to the cis-Golgi.
|
7 | O75340 (/IMP) O75340 (/IMP) O75340 (/IMP) O75340 (/IMP) O75340 (/IMP) O75340 (/IMP) O75340 (/IMP) |
Positive regulation of endothelial cell migration GO:0010595
Any process that increases the rate, frequency, or extent of the orderly movement of an endothelial cell into the extracellular matrix to form an endothelium.
|
7 | O75340 (/IDA) O75340 (/IDA) O75340 (/IDA) O75340 (/IDA) O75340 (/IDA) O75340 (/IDA) O75340 (/IDA) |
Neural crest formation GO:0014029
The formation of the specialized region of ectoderm between the neural ectoderm (neural plate) and non-neural ectoderm. The neural crest gives rise to the neural crest cells that migrate away from this region as neural tube formation procedes.
|
7 | O75340 (/IMP) O75340 (/IMP) O75340 (/IMP) O75340 (/IMP) O75340 (/IMP) O75340 (/IMP) O75340 (/IMP) |
Neural crest cell development GO:0014032
The process aimed at the progression of a neural crest cell over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell.
|
7 | O75340 (/IMP) O75340 (/IMP) O75340 (/IMP) O75340 (/IMP) O75340 (/IMP) O75340 (/IMP) O75340 (/IMP) |
Negative regulation of vascular endothelial growth factor receptor signaling pathway GO:0030948
Any process that stops, prevents, or reduces the frequency, rate or extent of vascular endothelial growth factor receptor signaling pathway activity.
|
7 | O75340 (/IDA) O75340 (/IDA) O75340 (/IDA) O75340 (/IDA) O75340 (/IDA) O75340 (/IDA) O75340 (/IDA) |
Negative regulation of TOR signaling GO:0032007
Any process that stops, prevents, or reduces the frequency, rate or extent of TOR signaling.
|
7 | O75340 (/IDA) O75340 (/IDA) O75340 (/IDA) O75340 (/IDA) O75340 (/IDA) O75340 (/IDA) O75340 (/IDA) |
Cellular response to heat GO:0034605
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism.
|
7 | O75340 (/IDA) O75340 (/IDA) O75340 (/IDA) O75340 (/IDA) O75340 (/IDA) O75340 (/IDA) O75340 (/IDA) |
Vascular endothelial growth factor receptor-2 signaling pathway GO:0036324
Any series of molecular signals initiated by the binding of an extracellular ligand to a vascular endothelial growth factor receptor-2 (VEGFR-2) located on the surface of the receiving cell, and ending with regulation of a downstream cellular process, e.g. transcription.
|
7 | O75340 (/IDA) O75340 (/IDA) O75340 (/IDA) O75340 (/IDA) O75340 (/IDA) O75340 (/IDA) O75340 (/IDA) |
Positive regulation of cysteine-type endopeptidase activity involved in apoptotic process GO:0043280
Any process that activates or increases the activity of a cysteine-type endopeptidase involved in the apoptotic process.
|
7 | O75340 (/IDA) O75340 (/IDA) O75340 (/IDA) O75340 (/IDA) O75340 (/IDA) O75340 (/IDA) O75340 (/IDA) |
Positive regulation of angiogenesis GO:0045766
Any process that activates or increases angiogenesis.
|
7 | O75340 (/IDA) O75340 (/IDA) O75340 (/IDA) O75340 (/IDA) O75340 (/IDA) O75340 (/IDA) O75340 (/IDA) |
COPII vesicle coating GO:0048208
The addition of COPII proteins and adaptor proteins to ER membranes during the formation of transport vesicles, forming a vesicle coat.
|
7 | O75340 (/IMP) O75340 (/IMP) O75340 (/IMP) O75340 (/IMP) O75340 (/IMP) O75340 (/IMP) O75340 (/IMP) |
Response to calcium ion GO:0051592
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a calcium ion stimulus.
|
7 | O75340 (/ISS) O75340 (/ISS) O75340 (/ISS) O75340 (/ISS) O75340 (/ISS) O75340 (/ISS) O75340 (/ISS) |
Negative regulation of protein kinase B signaling GO:0051898
Any process that stops, prevents, or reduces the frequency, rate or extent of protein kinase B signaling, a series of reactions mediated by the intracellular serine/threonine kinase protein kinase B.
|
7 | O75340 (/IDA) O75340 (/IDA) O75340 (/IDA) O75340 (/IDA) O75340 (/IDA) O75340 (/IDA) O75340 (/IDA) |
Apoptotic signaling pathway GO:0097190
A series of molecular signals which triggers the apoptotic death of a cell. The pathway starts with reception of a signal, and ends when the execution phase of apoptosis is triggered.
|
7 | O75340 (/TAS) O75340 (/TAS) O75340 (/TAS) O75340 (/TAS) O75340 (/TAS) O75340 (/TAS) O75340 (/TAS) |
Positive regulation of protein monoubiquitination GO:1902527
Any process that activates or increases the frequency, rate or extent of protein monoubiquitination.
|
7 | O75340 (/IMP) O75340 (/IMP) O75340 (/IMP) O75340 (/IMP) O75340 (/IMP) O75340 (/IMP) O75340 (/IMP) |
Endoplasmic reticulum to Golgi vesicle-mediated transport GO:0006888
The directed movement of substances from the endoplasmic reticulum (ER) to the Golgi, mediated by COP II vesicles. Small COP II coated vesicles form from the ER and then fuse directly with the cis-Golgi. Larger structures are transported along microtubules to the cis-Golgi.
|
2 | G3V7W1 (/ISS) P12815 (/ISS) |
Neural crest formation GO:0014029
The formation of the specialized region of ectoderm between the neural ectoderm (neural plate) and non-neural ectoderm. The neural crest gives rise to the neural crest cells that migrate away from this region as neural tube formation procedes.
|
2 | G3V7W1 (/ISS) P12815 (/ISS) |
Neural crest cell development GO:0014032
The process aimed at the progression of a neural crest cell over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell.
|
2 | G3V7W1 (/ISS) P12815 (/ISS) |
COPII vesicle coating GO:0048208
The addition of COPII proteins and adaptor proteins to ER membranes during the formation of transport vesicles, forming a vesicle coat.
|
2 | G3V7W1 (/ISS) P12815 (/ISS) |
Positive regulation of protein monoubiquitination GO:1902527
Any process that activates or increases the frequency, rate or extent of protein monoubiquitination.
|
2 | G3V7W1 (/ISS) P12815 (/ISS) |
Positive regulation of endothelial cell proliferation GO:0001938
Any process that activates or increases the rate or extent of endothelial cell proliferation.
|
1 | P12815 (/ISO) |
Positive regulation of endothelial cell proliferation GO:0001938
Any process that activates or increases the rate or extent of endothelial cell proliferation.
|
1 | P12815 (/ISS) |
Intracellular protein transport GO:0006886
The directed movement of proteins in a cell, including the movement of proteins between specific compartments or structures within a cell, such as organelles of a eukaryotic cell.
|
1 | P12815 (/ISO) |
Intracellular protein transport GO:0006886
The directed movement of proteins in a cell, including the movement of proteins between specific compartments or structures within a cell, such as organelles of a eukaryotic cell.
|
1 | P12815 (/ISS) |
Endoplasmic reticulum to Golgi vesicle-mediated transport GO:0006888
The directed movement of substances from the endoplasmic reticulum (ER) to the Golgi, mediated by COP II vesicles. Small COP II coated vesicles form from the ER and then fuse directly with the cis-Golgi. Larger structures are transported along microtubules to the cis-Golgi.
|
1 | P12815 (/ISO) |
Apoptotic process GO:0006915
A programmed cell death process which begins when a cell receives an internal (e.g. DNA damage) or external signal (e.g. an extracellular death ligand), and proceeds through a series of biochemical events (signaling pathway phase) which trigger an execution phase. The execution phase is the last step of an apoptotic process, and is typically characterized by rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), plasma membrane blebbing and fragmentation of the cell into apoptotic bodies. When the execution phase is completed, the cell has died.
|
1 | P12815 (/IDA) |
Activation of cysteine-type endopeptidase activity involved in apoptotic process GO:0006919
Any process that initiates the activity of the inactive enzyme cysteine-type endopeptidase in the context of an apoptotic process.
|
1 | P12815 (/IDA) |
Positive regulation of endothelial cell migration GO:0010595
Any process that increases the rate, frequency, or extent of the orderly movement of an endothelial cell into the extracellular matrix to form an endothelium.
|
1 | P12815 (/ISO) |
Positive regulation of endothelial cell migration GO:0010595
Any process that increases the rate, frequency, or extent of the orderly movement of an endothelial cell into the extracellular matrix to form an endothelium.
|
1 | P12815 (/ISS) |
Neural crest formation GO:0014029
The formation of the specialized region of ectoderm between the neural ectoderm (neural plate) and non-neural ectoderm. The neural crest gives rise to the neural crest cells that migrate away from this region as neural tube formation procedes.
|
1 | P12815 (/ISO) |
Neural crest cell development GO:0014032
The process aimed at the progression of a neural crest cell over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell.
|
1 | P12815 (/ISO) |
Negative regulation of vascular endothelial growth factor receptor signaling pathway GO:0030948
Any process that stops, prevents, or reduces the frequency, rate or extent of vascular endothelial growth factor receptor signaling pathway activity.
|
1 | P12815 (/ISO) |
Negative regulation of vascular endothelial growth factor receptor signaling pathway GO:0030948
Any process that stops, prevents, or reduces the frequency, rate or extent of vascular endothelial growth factor receptor signaling pathway activity.
|
1 | P12815 (/ISS) |
Negative regulation of TOR signaling GO:0032007
Any process that stops, prevents, or reduces the frequency, rate or extent of TOR signaling.
|
1 | P12815 (/ISO) |
Negative regulation of TOR signaling GO:0032007
Any process that stops, prevents, or reduces the frequency, rate or extent of TOR signaling.
|
1 | P12815 (/ISS) |
Cellular response to heat GO:0034605
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism.
|
1 | P12815 (/ISO) |
Cellular response to heat GO:0034605
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism.
|
1 | P12815 (/ISS) |
Vascular endothelial growth factor receptor-2 signaling pathway GO:0036324
Any series of molecular signals initiated by the binding of an extracellular ligand to a vascular endothelial growth factor receptor-2 (VEGFR-2) located on the surface of the receiving cell, and ending with regulation of a downstream cellular process, e.g. transcription.
|
1 | P12815 (/ISO) |
Vascular endothelial growth factor receptor-2 signaling pathway GO:0036324
Any series of molecular signals initiated by the binding of an extracellular ligand to a vascular endothelial growth factor receptor-2 (VEGFR-2) located on the surface of the receiving cell, and ending with regulation of a downstream cellular process, e.g. transcription.
|
1 | P12815 (/ISS) |
Positive regulation of cysteine-type endopeptidase activity involved in apoptotic process GO:0043280
Any process that activates or increases the activity of a cysteine-type endopeptidase involved in the apoptotic process.
|
1 | P12815 (/ISO) |
Positive regulation of angiogenesis GO:0045766
Any process that activates or increases angiogenesis.
|
1 | P12815 (/ISO) |
Positive regulation of angiogenesis GO:0045766
Any process that activates or increases angiogenesis.
|
1 | P12815 (/ISS) |
Positive regulation of JNK cascade GO:0046330
Any process that activates or increases the frequency, rate or extent of signal transduction mediated by the JNK cascade.
|
1 | Q8SYT2 (/IDA) |
COPII vesicle coating GO:0048208
The addition of COPII proteins and adaptor proteins to ER membranes during the formation of transport vesicles, forming a vesicle coat.
|
1 | P12815 (/ISO) |
Response to calcium ion GO:0051592
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a calcium ion stimulus.
|
1 | P12815 (/IDA) |
Negative regulation of protein kinase B signaling GO:0051898
Any process that stops, prevents, or reduces the frequency, rate or extent of protein kinase B signaling, a series of reactions mediated by the intracellular serine/threonine kinase protein kinase B.
|
1 | P12815 (/ISO) |
Negative regulation of protein kinase B signaling GO:0051898
Any process that stops, prevents, or reduces the frequency, rate or extent of protein kinase B signaling, a series of reactions mediated by the intracellular serine/threonine kinase protein kinase B.
|
1 | P12815 (/ISS) |
Positive regulation of protein monoubiquitination GO:1902527
Any process that activates or increases the frequency, rate or extent of protein monoubiquitination.
|
1 | P12815 (/ISO) |
There are 18 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
8 | O75340 (/IDA) O75340 (/IDA) O75340 (/IDA) O75340 (/IDA) O75340 (/IDA) O75340 (/IDA) O75340 (/IDA) P12815 (/IDA) |
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
7 | O75340 (/IDA) O75340 (/IDA) O75340 (/IDA) O75340 (/IDA) O75340 (/IDA) O75340 (/IDA) O75340 (/IDA) |
Endoplasmic reticulum GO:0005783
The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).
|
7 | O75340 (/IDA) O75340 (/IDA) O75340 (/IDA) O75340 (/IDA) O75340 (/IDA) O75340 (/IDA) O75340 (/IDA) |
COPII vesicle coat GO:0030127
One of two multimeric complexes that forms a membrane vesicle coat. COPII is best characterized in S. cerevisiae, where the subunits are called Sar1p, Sec13p, Sec31p, Sec23p, and Sec24p. Vesicles with COPII coats are found associated with endoplasmic reticulum (ER) membranes at steady state.
|
7 | O75340 (/IDA) O75340 (/IDA) O75340 (/IDA) O75340 (/IDA) O75340 (/IDA) O75340 (/IDA) O75340 (/IDA) |
Cytoplasmic vesicle GO:0031410
A vesicle found in the cytoplasm of a cell.
|
7 | O75340 (/IDA) O75340 (/IDA) O75340 (/IDA) O75340 (/IDA) O75340 (/IDA) O75340 (/IDA) O75340 (/IDA) |
Extracellular exosome GO:0070062
A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.
|
7 | O75340 (/HDA) O75340 (/HDA) O75340 (/HDA) O75340 (/HDA) O75340 (/HDA) O75340 (/HDA) O75340 (/HDA) |
Endoplasmic reticulum exit site GO:0070971
An endoplasmic reticulum part at which COPII-coated vesicles are produced.
|
7 | O75340 (/IDA) O75340 (/IDA) O75340 (/IDA) O75340 (/IDA) O75340 (/IDA) O75340 (/IDA) O75340 (/IDA) |
Endoplasmic reticulum exit site GO:0070971
An endoplasmic reticulum part at which COPII-coated vesicles are produced.
|
7 | O75340 (/IMP) O75340 (/IMP) O75340 (/IMP) O75340 (/IMP) O75340 (/IMP) O75340 (/IMP) O75340 (/IMP) |
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
2 | G3V7W1 (/ISS) P12815 (/ISS) |
COPII vesicle coat GO:0030127
One of two multimeric complexes that forms a membrane vesicle coat. COPII is best characterized in S. cerevisiae, where the subunits are called Sar1p, Sec13p, Sec31p, Sec23p, and Sec24p. Vesicles with COPII coats are found associated with endoplasmic reticulum (ER) membranes at steady state.
|
2 | G3V7W1 (/ISS) P12815 (/ISS) |
Endoplasmic reticulum exit site GO:0070971
An endoplasmic reticulum part at which COPII-coated vesicles are produced.
|
2 | G3V7W1 (/ISS) P12815 (/ISS) |
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
1 | P12815 (/ISO) |
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
1 | P12815 (/ISO) |
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
1 | G3V7W1 (/ISS) |
Endoplasmic reticulum GO:0005783
The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).
|
1 | P12815 (/ISO) |
COPII vesicle coat GO:0030127
One of two multimeric complexes that forms a membrane vesicle coat. COPII is best characterized in S. cerevisiae, where the subunits are called Sar1p, Sec13p, Sec31p, Sec23p, and Sec24p. Vesicles with COPII coats are found associated with endoplasmic reticulum (ER) membranes at steady state.
|
1 | P12815 (/ISO) |
Cytoplasmic vesicle GO:0031410
A vesicle found in the cytoplasm of a cell.
|
1 | P12815 (/ISO) |
Endoplasmic reticulum exit site GO:0070971
An endoplasmic reticulum part at which COPII-coated vesicles are produced.
|
1 | P12815 (/ISO) |