The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:

"
EF-hand
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 168: Solute carrier family 25 member 24

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 6 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
ATP transmembrane transporter activity GO:0005347
Enables the transfer of ATP, adenosine triphosphate, from one side of a membrane to the other.
8 O18757 (/ISS) Q5XHA0 (/ISS) Q66L49 (/ISS) Q7T0U6 (/ISS) Q7T0U6 (/ISS) Q7ZY36 (/ISS) Q7ZY36 (/ISS) Q8BMD8 (/ISS)
Calcium ion binding GO:0005509
Interacting selectively and non-covalently with calcium ions (Ca2+).
8 O18757 (/ISS) Q5XHA0 (/ISS) Q66L49 (/ISS) Q7T0U6 (/ISS) Q7T0U6 (/ISS) Q7ZY36 (/ISS) Q7ZY36 (/ISS) Q8BMD8 (/ISS)
ATP transmembrane transporter activity GO:0005347
Enables the transfer of ATP, adenosine triphosphate, from one side of a membrane to the other.
1 Q6NUK1 (/IMP)
ATP transmembrane transporter activity GO:0005347
Enables the transfer of ATP, adenosine triphosphate, from one side of a membrane to the other.
1 Q8BMD8 (/ISO)
Calcium ion binding GO:0005509
Interacting selectively and non-covalently with calcium ions (Ca2+).
1 Q6NUK1 (/IDA)
Calcium ion binding GO:0005509
Interacting selectively and non-covalently with calcium ions (Ca2+).
1 Q8BMD8 (/ISO)

There are 15 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Mitochondrial transport GO:0006839
Transport of substances into, out of or within a mitochondrion.
8 O18757 (/ISS) Q5XHA0 (/ISS) Q66L49 (/ISS) Q7T0U6 (/ISS) Q7T0U6 (/ISS) Q7ZY36 (/ISS) Q7ZY36 (/ISS) Q8BMD8 (/ISS)
Regulation of cell death GO:0010941
Any process that modulates the rate or frequency of cell death. Cell death is the specific activation or halting of processes within a cell so that its vital functions markedly cease, rather than simply deteriorating gradually over time, which culminates in cell death.
8 O18757 (/ISS) Q5XHA0 (/ISS) Q66L49 (/ISS) Q7T0U6 (/ISS) Q7T0U6 (/ISS) Q7ZY36 (/ISS) Q7ZY36 (/ISS) Q8BMD8 (/ISS)
ATP transport GO:0015867
The directed movement of ATP, adenosine triphosphate, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
8 O18757 (/ISS) Q5XHA0 (/ISS) Q66L49 (/ISS) Q7T0U6 (/ISS) Q7T0U6 (/ISS) Q7ZY36 (/ISS) Q7ZY36 (/ISS) Q8BMD8 (/ISS)
Cellular response to oxidative stress GO:0034599
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.
8 O18757 (/ISS) Q5XHA0 (/ISS) Q66L49 (/ISS) Q7T0U6 (/ISS) Q7T0U6 (/ISS) Q7ZY36 (/ISS) Q7ZY36 (/ISS) Q8BMD8 (/ISS)
Cellular response to calcium ion GO:0071277
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a calcium ion stimulus.
8 O18757 (/ISS) Q5XHA0 (/ISS) Q66L49 (/ISS) Q7T0U6 (/ISS) Q7T0U6 (/ISS) Q7ZY36 (/ISS) Q7ZY36 (/ISS) Q8BMD8 (/ISS)
Mitochondrial transport GO:0006839
Transport of substances into, out of or within a mitochondrion.
1 Q6NUK1 (/IMP)
Mitochondrial transport GO:0006839
Transport of substances into, out of or within a mitochondrion.
1 Q8BMD8 (/ISO)
Regulation of cell death GO:0010941
Any process that modulates the rate or frequency of cell death. Cell death is the specific activation or halting of processes within a cell so that its vital functions markedly cease, rather than simply deteriorating gradually over time, which culminates in cell death.
1 Q6NUK1 (/IMP)
Regulation of cell death GO:0010941
Any process that modulates the rate or frequency of cell death. Cell death is the specific activation or halting of processes within a cell so that its vital functions markedly cease, rather than simply deteriorating gradually over time, which culminates in cell death.
1 Q8BMD8 (/ISO)
ATP transport GO:0015867
The directed movement of ATP, adenosine triphosphate, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
1 Q6NUK1 (/IMP)
ATP transport GO:0015867
The directed movement of ATP, adenosine triphosphate, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
1 Q8BMD8 (/ISO)
Cellular response to oxidative stress GO:0034599
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.
1 Q6NUK1 (/IMP)
Cellular response to oxidative stress GO:0034599
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.
1 Q8BMD8 (/ISO)
Cellular response to calcium ion GO:0071277
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a calcium ion stimulus.
1 Q6NUK1 (/IMP)
Cellular response to calcium ion GO:0071277
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a calcium ion stimulus.
1 Q8BMD8 (/ISO)

There are 10 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Integral component of membrane GO:0016021
The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
8 O18757 (/ISS) Q5XHA0 (/ISS) Q66L49 (/ISS) Q7T0U6 (/ISS) Q7T0U6 (/ISS) Q7ZY36 (/ISS) Q7ZY36 (/ISS) Q8BMD8 (/ISS)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
7 O18757 (/ISS) Q5XHA0 (/ISS) Q66L49 (/ISS) Q7T0U6 (/ISS) Q7T0U6 (/ISS) Q7ZY36 (/ISS) Q7ZY36 (/ISS)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
4 B1AUS6 (/IDA) Q6NUK1 (/IDA) Q8BMD8 (/IDA) Q9D5G5 (/IDA)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
3 B1AUS6 (/HDA) Q8BMD8 (/HDA) Q9D5G5 (/HDA)
Microtubule organizing center GO:0005815
An intracellular structure that can catalyze gamma-tubulin-dependent microtubule nucleation and that can anchor microtubules by interacting with their minus ends, plus ends or sides.
2 B1AUS6 (/IDA) Q9D5G5 (/IDA)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
2 B1AUS6 (/IDA) Q9D5G5 (/IDA)
Chromatoid body GO:0033391
A ribonucleoprotein complex found in the cytoplasm of male germ cells, composed of exceedingly thin filaments that are consolidated into a compact mass or into dense strands of varying thickness that branch to form an irregular network. Contains mRNAs, miRNAs, and protein components involved in miRNA processing (such as Argonaute proteins and the endonuclease Dicer) and in RNA decay (such as the decapping enzyme DCP1a and GW182).
2 B1AUS6 (/IDA) Q9D5G5 (/IDA)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
1 Q8BMD8 (/ISO)
Integral component of membrane GO:0016021
The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
1 Q6NUK1 (/IDA)
Integral component of membrane GO:0016021
The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
1 Q8BMD8 (/ISO)
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