The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:

"
EF-hand
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 152: Centrin 3

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 3 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
19 O15182 (/IPI) O15182 (/IPI) O15182 (/IPI) O15182 (/IPI) O15182 (/IPI) O15182 (/IPI) O15182 (/IPI) O15182 (/IPI) O15182 (/IPI) O15182 (/IPI)
(9 more)
Microtubule binding GO:0008017
Interacting selectively and non-covalently with microtubules, filaments composed of tubulin monomers.
3 O35648 (/IDA) O35648 (/IDA) O35648 (/IDA)
G-protein beta/gamma-subunit complex binding GO:0031683
Interacting selectively and non-covalently with a complex of G-protein beta/gamma subunits.
3 O35648 (/IDA) O35648 (/IDA) O35648 (/IDA)

There are 1 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Centrosome cycle GO:0007098
The cell cycle process in which centrosome duplication and separation takes place. The centrosome cycle can operate with a considerable degree of independence from other processes of the cell cycle.
19 O15182 (/TAS) O15182 (/TAS) O15182 (/TAS) O15182 (/TAS) O15182 (/TAS) O15182 (/TAS) O15182 (/TAS) O15182 (/TAS) O15182 (/TAS) O15182 (/TAS)
(9 more)

There are 14 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Centriole GO:0005814
A cellular organelle, found close to the nucleus in many eukaryotic cells, consisting of a small cylinder with microtubular walls, 300-500 nm long and 150-250 nm in diameter. It contains nine short, parallel, peripheral microtubular fibrils, each fibril consisting of one complete microtubule fused to two incomplete microtubules. Cells usually have two centrioles, lying at right angles to each other. At division, each pair of centrioles generates another pair and the twin pairs form the pole of the mitotic spindle.
22 O15182 (/IDA) O15182 (/IDA) O15182 (/IDA) O15182 (/IDA) O15182 (/IDA) O15182 (/IDA) O15182 (/IDA) O15182 (/IDA) O15182 (/IDA) O15182 (/IDA)
(12 more)
Centrosome GO:0005813
A structure comprised of a core structure (in most organisms, a pair of centrioles) and peripheral material from which a microtubule-based structure, such as a spindle apparatus, is organized. Centrosomes occur close to the nucleus during interphase in many eukaryotic cells, though in animal cells it changes continually during the cell-division cycle.
19 O15182 (/IDA) O15182 (/IDA) O15182 (/IDA) O15182 (/IDA) O15182 (/IDA) O15182 (/IDA) O15182 (/IDA) O15182 (/IDA) O15182 (/IDA) O15182 (/IDA)
(9 more)
Centriole GO:0005814
A cellular organelle, found close to the nucleus in many eukaryotic cells, consisting of a small cylinder with microtubular walls, 300-500 nm long and 150-250 nm in diameter. It contains nine short, parallel, peripheral microtubular fibrils, each fibril consisting of one complete microtubule fused to two incomplete microtubules. Cells usually have two centrioles, lying at right angles to each other. At division, each pair of centrioles generates another pair and the twin pairs form the pole of the mitotic spindle.
19 O15182 (/TAS) O15182 (/TAS) O15182 (/TAS) O15182 (/TAS) O15182 (/TAS) O15182 (/TAS) O15182 (/TAS) O15182 (/TAS) O15182 (/TAS) O15182 (/TAS)
(9 more)
Nuclear pore nuclear basket GO:0044615
A filamentous, cage-like assembly on the nuclear face of the nuclear pore complex (NPC). In S. cerevisiae, Mlp1p and Mlp2p are two major components of the NPC nuclear basket. In vertebrates, Tpr is a major component.
19 O15182 (/IDA) O15182 (/IDA) O15182 (/IDA) O15182 (/IDA) O15182 (/IDA) O15182 (/IDA) O15182 (/IDA) O15182 (/IDA) O15182 (/IDA) O15182 (/IDA)
(9 more)
Transcription export complex 2 GO:0070390
A protein complex that couples SAGA-dependent gene expression to mRNA export at the inner side of the nuclear pore complex (NPC). The TREX-2 complex is tethered to the inner side of the NPC via the nucleoporins Nup1 and Nup60; in S. cerevisiae it contains Sac3p, Thp1p, Sem1, Sus1p and Cdc31p.
19 O15182 (/IDA) O15182 (/IDA) O15182 (/IDA) O15182 (/IDA) O15182 (/IDA) O15182 (/IDA) O15182 (/IDA) O15182 (/IDA) O15182 (/IDA) O15182 (/IDA)
(9 more)
Centrosome GO:0005813
A structure comprised of a core structure (in most organisms, a pair of centrioles) and peripheral material from which a microtubule-based structure, such as a spindle apparatus, is organized. Centrosomes occur close to the nucleus during interphase in many eukaryotic cells, though in animal cells it changes continually during the cell-division cycle.
3 O35648 (/ISO) O35648 (/ISO) O35648 (/ISO)
Centriole GO:0005814
A cellular organelle, found close to the nucleus in many eukaryotic cells, consisting of a small cylinder with microtubular walls, 300-500 nm long and 150-250 nm in diameter. It contains nine short, parallel, peripheral microtubular fibrils, each fibril consisting of one complete microtubule fused to two incomplete microtubules. Cells usually have two centrioles, lying at right angles to each other. At division, each pair of centrioles generates another pair and the twin pairs form the pole of the mitotic spindle.
3 O35648 (/ISO) O35648 (/ISO) O35648 (/ISO)
Photoreceptor connecting cilium GO:0032391
The portion of the photoreceptor cell cilium linking the photoreceptor inner and outer segments. It's considered to be equivalent to the ciliary transition zone.
3 O35648 (/IDA) O35648 (/IDA) O35648 (/IDA)
Ciliary transition zone GO:0035869
A region of the cilium between the basal body and proximal segment that is characterized by Y-shaped assemblages that connect axonemal microtubules to the ciliary membrane. The ciliary transition zone appears to function as a gate that controls ciliary membrane composition and separates the cytosol from the ciliary plasm.
3 O35648 (/IDA) O35648 (/IDA) O35648 (/IDA)
Ciliary basal body GO:0036064
A membrane-tethered, short cylindrical array of microtubules and associated proteins found at the base of a eukaryotic cilium (also called flagellum) that is similar in structure to a centriole and derives from it. The cilium basal body is the site of assembly and remodelling of the cilium and serves as a nucleation site for axoneme growth. As well as anchoring the cilium, it is thought to provide a selective gateway regulating the entry of ciliary proteins and vesicles by intraflagellar transport.
3 O35648 (/IDA) O35648 (/IDA) O35648 (/IDA)
Nuclear pore nuclear basket GO:0044615
A filamentous, cage-like assembly on the nuclear face of the nuclear pore complex (NPC). In S. cerevisiae, Mlp1p and Mlp2p are two major components of the NPC nuclear basket. In vertebrates, Tpr is a major component.
3 O35648 (/ISO) O35648 (/ISO) O35648 (/ISO)
Nuclear pore nuclear basket GO:0044615
A filamentous, cage-like assembly on the nuclear face of the nuclear pore complex (NPC). In S. cerevisiae, Mlp1p and Mlp2p are two major components of the NPC nuclear basket. In vertebrates, Tpr is a major component.
3 O35648 (/ISS) O35648 (/ISS) O35648 (/ISS)
Transcription export complex 2 GO:0070390
A protein complex that couples SAGA-dependent gene expression to mRNA export at the inner side of the nuclear pore complex (NPC). The TREX-2 complex is tethered to the inner side of the NPC via the nucleoporins Nup1 and Nup60; in S. cerevisiae it contains Sac3p, Thp1p, Sem1, Sus1p and Cdc31p.
3 O35648 (/ISO) O35648 (/ISO) O35648 (/ISO)
Transcription export complex 2 GO:0070390
A protein complex that couples SAGA-dependent gene expression to mRNA export at the inner side of the nuclear pore complex (NPC). The TREX-2 complex is tethered to the inner side of the NPC via the nucleoporins Nup1 and Nup60; in S. cerevisiae it contains Sac3p, Thp1p, Sem1, Sus1p and Cdc31p.
3 O35648 (/ISS) O35648 (/ISS) O35648 (/ISS)
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