The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:
"EF-hand
".
FunFam 131: Dystrophin, isoform E
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 4 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Actin binding GO:0003779
Interacting selectively and non-covalently with monomeric or multimeric forms of actin, including actin filaments.
|
4 | Q0KI50 (/ISS) Q7YU29 (/ISS) Q9VDW3 (/ISS) Q9VDW6 (/ISS) |
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
4 | Q0KI50 (/IPI) Q7YU29 (/IPI) Q9VDW3 (/IPI) Q9VDW6 (/IPI) |
Structural constituent of muscle GO:0008307
The action of a molecule that contributes to the structural integrity of a muscle fiber.
|
4 | Q0KI50 (/ISS) Q7YU29 (/ISS) Q9VDW3 (/ISS) Q9VDW6 (/ISS) |
WW domain binding GO:0050699
Interacting selectively and non-covalently with a WW domain of a protein, a small module composed of 40 amino acids and plays a role in mediating protein-protein interactions via proline-rich regions.
|
4 | Q0KI50 (/IPI) Q7YU29 (/IPI) Q9VDW3 (/IPI) Q9VDW6 (/IPI) |
There are 9 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Neuromuscular synaptic transmission GO:0007274
The process of synaptic transmission from a neuron to a muscle, across a synapse.
|
4 | Q0KI50 (/IDA) Q7YU29 (/IDA) Q9VDW3 (/IDA) Q9VDW6 (/IDA) |
Imaginal disc-derived wing vein specification GO:0007474
The regionalization process in which the area of a imaginal disc-derived wing that will form a wing vein is specified.
|
4 | Q0KI50 (/IMP) Q7YU29 (/IMP) Q9VDW3 (/IMP) Q9VDW6 (/IMP) |
Imaginal disc-derived wing vein morphogenesis GO:0008586
The process in which anatomical structures of the veins on an imaginal disc-derived wing are generated and organized.
|
4 | Q0KI50 (/IMP) Q7YU29 (/IMP) Q9VDW3 (/IMP) Q9VDW6 (/IMP) |
Establishment of cell polarity GO:0030010
The specification and formation of anisotropic intracellular organization or cell growth patterns.
|
4 | Q0KI50 (/IMP) Q7YU29 (/IMP) Q9VDW3 (/IMP) Q9VDW6 (/IMP) |
Muscle cell cellular homeostasis GO:0046716
The cellular homeostatic process that preserves a muscle cell in a stable functional or structural state.
|
4 | Q0KI50 (/IMP) Q7YU29 (/IMP) Q9VDW3 (/IMP) Q9VDW6 (/IMP) |
Regulation of neurotransmitter secretion GO:0046928
Any process that modulates the frequency, rate or extent of the regulated release of a neurotransmitter from a cell.
|
4 | Q0KI50 (/IDA) Q7YU29 (/IDA) Q9VDW3 (/IDA) Q9VDW6 (/IDA) |
Regulation of neurotransmitter secretion GO:0046928
Any process that modulates the frequency, rate or extent of the regulated release of a neurotransmitter from a cell.
|
4 | Q0KI50 (/IMP) Q7YU29 (/IMP) Q9VDW3 (/IMP) Q9VDW6 (/IMP) |
Regulation of short-term neuronal synaptic plasticity GO:0048172
A process that modulates short-term neuronal synaptic plasticity, the ability of neuronal synapses to change in the short-term as circumstances require. Short-term neuronal synaptic plasticity generally involves increasing or decreasing synaptic sensitivity.
|
4 | Q0KI50 (/IDA) Q7YU29 (/IDA) Q9VDW3 (/IDA) Q9VDW6 (/IDA) |
Muscle organ development GO:0007517
The process whose specific outcome is the progression of the muscle over time, from its formation to the mature structure. The muscle is an organ consisting of a tissue made up of various elongated cells that are specialized to contract and thus to produce movement and mechanical work.
|
3 | Q0KI50 (/IMP) Q7YU29 (/IMP) Q9VDW3 (/IMP) |
There are 7 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
4 | Q0KI50 (/HDA) Q7YU29 (/HDA) Q9VDW3 (/HDA) Q9VDW6 (/HDA) |
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
4 | Q0KI50 (/IDA) Q7YU29 (/IDA) Q9VDW3 (/IDA) Q9VDW6 (/IDA) |
Cytoskeleton GO:0005856
Any of the various filamentous elements that form the internal framework of cells, and typically remain after treatment of the cells with mild detergent to remove membrane constituents and soluble components of the cytoplasm. The term embraces intermediate filaments, microfilaments, microtubules, the microtrabecular lattice, and other structures characterized by a polymeric filamentous nature and long-range order within the cell. The various elements of the cytoskeleton not only serve in the maintenance of cellular shape but also have roles in other cellular functions, including cellular movement, cell division, endocytosis, and movement of organelles.
|
4 | Q0KI50 (/IDA) Q7YU29 (/IDA) Q9VDW3 (/IDA) Q9VDW6 (/IDA) |
Cell cortex GO:0005938
The region of a cell that lies just beneath the plasma membrane and often, but not always, contains a network of actin filaments and associated proteins.
|
4 | Q0KI50 (/HDA) Q7YU29 (/HDA) Q9VDW3 (/HDA) Q9VDW6 (/HDA) |
Dystrophin-associated glycoprotein complex GO:0016010
A multiprotein complex that forms a strong mechanical link between the cytoskeleton and extracellular matrix; typical of, but not confined to, muscle cells. The complex is composed of transmembrane, cytoplasmic, and extracellular proteins, including dystrophin, sarcoglycans, dystroglycan, dystrobrevins, syntrophins, sarcospan, caveolin-3, and NO synthase.
|
4 | Q0KI50 (/IPI) Q7YU29 (/IPI) Q9VDW3 (/IPI) Q9VDW6 (/IPI) |
Dystrophin-associated glycoprotein complex GO:0016010
A multiprotein complex that forms a strong mechanical link between the cytoskeleton and extracellular matrix; typical of, but not confined to, muscle cells. The complex is composed of transmembrane, cytoplasmic, and extracellular proteins, including dystrophin, sarcoglycans, dystroglycan, dystrobrevins, syntrophins, sarcospan, caveolin-3, and NO synthase.
|
4 | Q0KI50 (/ISS) Q7YU29 (/ISS) Q9VDW3 (/ISS) Q9VDW6 (/ISS) |
Synapse GO:0045202
The junction between a nerve fiber of one neuron and another neuron, muscle fiber or glial cell. As the nerve fiber approaches the synapse it enlarges into a specialized structure, the presynaptic nerve ending, which contains mitochondria and synaptic vesicles. At the tip of the nerve ending is the presynaptic membrane; facing it, and separated from it by a minute cleft (the synaptic cleft) is a specialized area of membrane on the receiving cell, known as the postsynaptic membrane. In response to the arrival of nerve impulses, the presynaptic nerve ending secretes molecules of neurotransmitters into the synaptic cleft. These diffuse across the cleft and transmit the signal to the postsynaptic membrane.
|
4 | Q0KI50 (/IDA) Q7YU29 (/IDA) Q9VDW3 (/IDA) Q9VDW6 (/IDA) |