The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:

"
EF-hand
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 107: Troponin C, skeletal muscle

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 2 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
12 P02585 (/IPI) P02585 (/IPI) P02585 (/IPI) P02585 (/IPI) P02585 (/IPI) P02585 (/IPI) P02585 (/IPI) P02585 (/IPI) P02585 (/IPI) P02585 (/IPI)
(2 more)
Troponin T binding GO:0031014
Interacting selectively and non-covalently with troponin T, the tropomyosin-binding subunit of the troponin complex.
11 P02586 (/IPI) P02586 (/IPI) P02586 (/IPI) P02586 (/IPI) P02586 (/IPI) P02586 (/IPI) P02586 (/IPI) P02586 (/IPI) P02586 (/IPI) P02586 (/IPI)
(1 more)

There are 5 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Skeletal muscle contraction GO:0003009
A process in which force is generated within skeletal muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. In the skeletal muscle, the muscle contraction takes advantage of an ordered sarcomeric structure and in most cases it is under voluntary control.
12 P02585 (/IDA) P02585 (/IDA) P02585 (/IDA) P02585 (/IDA) P02585 (/IDA) P02585 (/IDA) P02585 (/IDA) P02585 (/IDA) P02585 (/IDA) P02585 (/IDA)
(2 more)
Regulation of muscle contraction GO:0006937
Any process that modulates the frequency, rate or extent of muscle contraction.
12 P02585 (/TAS) P02585 (/TAS) P02585 (/TAS) P02585 (/TAS) P02585 (/TAS) P02585 (/TAS) P02585 (/TAS) P02585 (/TAS) P02585 (/TAS) P02585 (/TAS)
(2 more)
Muscle filament sliding GO:0030049
The sliding of actin thin filaments and myosin thick filaments past each other in muscle contraction. This involves a process of interaction of myosin located on a thick filament with actin located on a thin filament. During this process ATP is split and forces are generated.
12 P02585 (/TAS) P02585 (/TAS) P02585 (/TAS) P02585 (/TAS) P02585 (/TAS) P02585 (/TAS) P02585 (/TAS) P02585 (/TAS) P02585 (/TAS) P02585 (/TAS)
(2 more)
Response to activity GO:0014823
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an activity stimulus.
3 A0A2R8QB55 (/IDA) E9QBF1 (/IDA) Q9I8U8 (/IDA)
Skeletal muscle contraction GO:0003009
A process in which force is generated within skeletal muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. In the skeletal muscle, the muscle contraction takes advantage of an ordered sarcomeric structure and in most cases it is under voluntary control.
2 P20801 (/ISO) P20801 (/ISO)

There are 4 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
12 P02585 (/TAS) P02585 (/TAS) P02585 (/TAS) P02585 (/TAS) P02585 (/TAS) P02585 (/TAS) P02585 (/TAS) P02585 (/TAS) P02585 (/TAS) P02585 (/TAS)
(2 more)
Troponin complex GO:0005861
A complex of accessory proteins (typically troponin T, troponin I and troponin C) found associated with actin in muscle thin filaments; involved in calcium regulation of muscle contraction.
12 P02585 (/IDA) P02585 (/IDA) P02585 (/IDA) P02585 (/IDA) P02585 (/IDA) P02585 (/IDA) P02585 (/IDA) P02585 (/IDA) P02585 (/IDA) P02585 (/IDA)
(2 more)
Troponin complex GO:0005861
A complex of accessory proteins (typically troponin T, troponin I and troponin C) found associated with actin in muscle thin filaments; involved in calcium regulation of muscle contraction.
2 P20801 (/ISO) P20801 (/ISO)
Myofilament GO:0036379
Any of the smallest contractile units of a myofibril (striated muscle fiber).
2 A0A060WZV7 (/IDA) A0A060YT85 (/IDA)
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