The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:
"GRIP domain
".
FunFam 3: GRIP and coiled-coil domain-containing protein 2
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 4 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
2 | Q8CHG3 (/IPI) Q8IWJ2 (/IPI) |
Ran GTPase binding GO:0008536
Interacting selectively and non-covalently with Ran, a conserved Ras-like GTP-binding protein, implicated in nucleocytoplasmic transport, cell cycle progression, spindle assembly, nuclear organization and nuclear envelope (NE) assembly.
|
1 | O14715 (/NAS) |
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
|
1 | Q8IWJ2 (/IPI) |
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
|
1 | Q8CHG3 (/ISO) |
There are 26 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Protein targeting to lysosome GO:0006622
The process of directing proteins towards the lysosome using signals contained within the protein.
|
2 | D3ZZL9 (/ISS) Q8CHG3 (/ISS) |
Microtubule organizing center organization GO:0031023
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a microtubule organizing center, a structure from which microtubules grow.
|
2 | D3ZZL9 (/ISS) Q8CHG3 (/ISS) |
Protein localization to Golgi apparatus GO:0034067
A process in which a protein is transported to, or maintained in, a location within the Golgi apparatus.
|
2 | D3ZZL9 (/ISS) Q8CHG3 (/ISS) |
Microtubule anchoring GO:0034453
Any process in which a microtubule is maintained in a specific location in a cell.
|
2 | D3ZZL9 (/ISS) Q8CHG3 (/ISS) |
Late endosome to Golgi transport GO:0034499
The directed movement of substances from late endosomes to the Golgi.
|
2 | D3ZZL9 (/ISS) Q8CHG3 (/ISS) |
Regulation of protein exit from endoplasmic reticulum GO:0070861
Any process that modulates the frequency, rate or extent of the directed movement of proteins from the endoplasmic reticulum.
|
2 | D3ZZL9 (/ISS) Q8CHG3 (/ISS) |
Recycling endosome to Golgi transport GO:0071955
The directed movement of substances from recycling endosomes to the Golgi.
|
2 | D3ZZL9 (/ISS) Q8CHG3 (/ISS) |
Golgi ribbon formation GO:0090161
The formation of a continuous ribbon of interconnected Golgi stacks of flat cisternae.
|
2 | D3ZZL9 (/ISS) Q8CHG3 (/ISS) |
Protein targeting to lysosome GO:0006622
The process of directing proteins towards the lysosome using signals contained within the protein.
|
1 | Q8IWJ2 (/IMP) |
Protein targeting to lysosome GO:0006622
The process of directing proteins towards the lysosome using signals contained within the protein.
|
1 | Q8CHG3 (/ISO) |
Microtubule organizing center organization GO:0031023
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a microtubule organizing center, a structure from which microtubules grow.
|
1 | Q8IWJ2 (/IMP) |
Microtubule organizing center organization GO:0031023
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a microtubule organizing center, a structure from which microtubules grow.
|
1 | Q8CHG3 (/ISO) |
Protein localization to Golgi apparatus GO:0034067
A process in which a protein is transported to, or maintained in, a location within the Golgi apparatus.
|
1 | Q8IWJ2 (/IMP) |
Protein localization to Golgi apparatus GO:0034067
A process in which a protein is transported to, or maintained in, a location within the Golgi apparatus.
|
1 | Q8CHG3 (/ISO) |
Microtubule anchoring GO:0034453
Any process in which a microtubule is maintained in a specific location in a cell.
|
1 | Q8IWJ2 (/IMP) |
Microtubule anchoring GO:0034453
Any process in which a microtubule is maintained in a specific location in a cell.
|
1 | Q8CHG3 (/ISO) |
Late endosome to Golgi transport GO:0034499
The directed movement of substances from late endosomes to the Golgi.
|
1 | Q8IWJ2 (/IMP) |
Late endosome to Golgi transport GO:0034499
The directed movement of substances from late endosomes to the Golgi.
|
1 | Q8CHG3 (/ISO) |
Retrograde transport, endosome to Golgi GO:0042147
The directed movement of membrane-bounded vesicles from endosomes back to the trans-Golgi network where they are recycled for further rounds of transport.
|
1 | Q8IWJ2 (/IMP) |
Retrograde transport, endosome to Golgi GO:0042147
The directed movement of membrane-bounded vesicles from endosomes back to the trans-Golgi network where they are recycled for further rounds of transport.
|
1 | Q8CHG3 (/ISO) |
Regulation of protein exit from endoplasmic reticulum GO:0070861
Any process that modulates the frequency, rate or extent of the directed movement of proteins from the endoplasmic reticulum.
|
1 | Q8IWJ2 (/IMP) |
Regulation of protein exit from endoplasmic reticulum GO:0070861
Any process that modulates the frequency, rate or extent of the directed movement of proteins from the endoplasmic reticulum.
|
1 | Q8CHG3 (/ISO) |
Recycling endosome to Golgi transport GO:0071955
The directed movement of substances from recycling endosomes to the Golgi.
|
1 | Q8IWJ2 (/IMP) |
Recycling endosome to Golgi transport GO:0071955
The directed movement of substances from recycling endosomes to the Golgi.
|
1 | Q8CHG3 (/ISO) |
Golgi ribbon formation GO:0090161
The formation of a continuous ribbon of interconnected Golgi stacks of flat cisternae.
|
1 | Q8IWJ2 (/IMP) |
Golgi ribbon formation GO:0090161
The formation of a continuous ribbon of interconnected Golgi stacks of flat cisternae.
|
1 | Q8CHG3 (/ISO) |
There are 10 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Trans-Golgi network GO:0005802
The network of interconnected tubular and cisternal structures located within the Golgi apparatus on the side distal to the endoplasmic reticulum, from which secretory vesicles emerge. The trans-Golgi network is important in the later stages of protein secretion where it is thought to play a key role in the sorting and targeting of secreted proteins to the correct destination.
|
2 | D3ZZL9 (/ISS) Q8CHG3 (/ISS) |
Nuclear pore GO:0005643
Any of the numerous similar discrete openings in the nuclear envelope of a eukaryotic cell, where the inner and outer nuclear membranes are joined.
|
1 | O14715 (/NAS) |
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
|
1 | Q8IWJ2 (/IDA) |
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
|
1 | Q8CHG3 (/ISO) |
Golgi apparatus GO:0005794
A compound membranous cytoplasmic organelle of eukaryotic cells, consisting of flattened, ribosome-free vesicles arranged in a more or less regular stack. The Golgi apparatus differs from the endoplasmic reticulum in often having slightly thicker membranes, appearing in sections as a characteristic shallow semicircle so that the convex side (cis or entry face) abuts the endoplasmic reticulum, secretory vesicles emerging from the concave side (trans or exit face). In vertebrate cells there is usually one such organelle, while in invertebrates and plants, where they are known usually as dictyosomes, there may be several scattered in the cytoplasm. The Golgi apparatus processes proteins produced on the ribosomes of the rough endoplasmic reticulum; such processing includes modification of the core oligosaccharides of glycoproteins, and the sorting and packaging of proteins for transport to a variety of cellular locations. Three different regions of the Golgi are now recognized both in terms of structure and function: cis, in the vicinity of the cis face, trans, in the vicinity of the trans face, and medial, lying between the cis and trans regions.
|
1 | Q8IWJ2 (/IDA) |
Golgi apparatus GO:0005794
A compound membranous cytoplasmic organelle of eukaryotic cells, consisting of flattened, ribosome-free vesicles arranged in a more or less regular stack. The Golgi apparatus differs from the endoplasmic reticulum in often having slightly thicker membranes, appearing in sections as a characteristic shallow semicircle so that the convex side (cis or entry face) abuts the endoplasmic reticulum, secretory vesicles emerging from the concave side (trans or exit face). In vertebrate cells there is usually one such organelle, while in invertebrates and plants, where they are known usually as dictyosomes, there may be several scattered in the cytoplasm. The Golgi apparatus processes proteins produced on the ribosomes of the rough endoplasmic reticulum; such processing includes modification of the core oligosaccharides of glycoproteins, and the sorting and packaging of proteins for transport to a variety of cellular locations. Three different regions of the Golgi are now recognized both in terms of structure and function: cis, in the vicinity of the cis face, trans, in the vicinity of the trans face, and medial, lying between the cis and trans regions.
|
1 | Q8CHG3 (/ISO) |
Trans-Golgi network GO:0005802
The network of interconnected tubular and cisternal structures located within the Golgi apparatus on the side distal to the endoplasmic reticulum, from which secretory vesicles emerge. The trans-Golgi network is important in the later stages of protein secretion where it is thought to play a key role in the sorting and targeting of secreted proteins to the correct destination.
|
1 | Q8IWJ2 (/IDA) |
Trans-Golgi network GO:0005802
The network of interconnected tubular and cisternal structures located within the Golgi apparatus on the side distal to the endoplasmic reticulum, from which secretory vesicles emerge. The trans-Golgi network is important in the later stages of protein secretion where it is thought to play a key role in the sorting and targeting of secreted proteins to the correct destination.
|
1 | Q8CHG3 (/ISO) |
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
1 | Q8IWJ2 (/TAS) |
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
|
1 | Q8IWJ2 (/HDA) |