The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:

"
Transcription termination and cleavage factor, C-terminal domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 5: Pti1p

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 1 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
8 P39927 (/IPI) P39927 (/IPI) P39927 (/IPI) P39927 (/IPI) P39927 (/IPI) P39927 (/IPI) P39927 (/IPI) P39927 (/IPI)

There are 6 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
MRNA polyadenylation GO:0006378
The enzymatic addition of a sequence of 40-200 adenylyl residues at the 3' end of a eukaryotic mRNA primary transcript.
8 P39927 (/IMP) P39927 (/IMP) P39927 (/IMP) P39927 (/IMP) P39927 (/IMP) P39927 (/IMP) P39927 (/IMP) P39927 (/IMP)
Termination of RNA polymerase II transcription, poly(A)-coupled GO:0030846
The process in which transcription of polyadenylated RNA polymerase II transcripts is terminated; cleavage and polyadenylylation of the mRNA 3' end is coupled to transcription termination.
8 P39927 (/IPI) P39927 (/IPI) P39927 (/IPI) P39927 (/IPI) P39927 (/IPI) P39927 (/IPI) P39927 (/IPI) P39927 (/IPI)
Termination of RNA polymerase II transcription, exosome-dependent GO:0030847
The process in which transcription of nonpolyadenylated RNA polymerase II transcripts is terminated; coupled to the maturation of the RNA 3'-end.
8 P39927 (/IMP) P39927 (/IMP) P39927 (/IMP) P39927 (/IMP) P39927 (/IMP) P39927 (/IMP) P39927 (/IMP) P39927 (/IMP)
Termination of RNA polymerase II transcription, exosome-dependent GO:0030847
The process in which transcription of nonpolyadenylated RNA polymerase II transcripts is terminated; coupled to the maturation of the RNA 3'-end.
8 P39927 (/IPI) P39927 (/IPI) P39927 (/IPI) P39927 (/IPI) P39927 (/IPI) P39927 (/IPI) P39927 (/IPI) P39927 (/IPI)
SnoRNA 3'-end processing GO:0031126
Any process involved in forming the mature 3' end of a snoRNA molecule.
8 P39927 (/IMP) P39927 (/IMP) P39927 (/IMP) P39927 (/IMP) P39927 (/IMP) P39927 (/IMP) P39927 (/IMP) P39927 (/IMP)
Pre-mRNA cleavage required for polyadenylation GO:0098789
The targeted, endonucleolytic cleavage of a pre-mRNA, required for polyadenylation of the 3' end. This cleavage is directed by binding sites near the 3' end of the mRNA and leaves a 3' hydoxyl end which then becomes a target for adenylation.
8 P39927 (/IMP) P39927 (/IMP) P39927 (/IMP) P39927 (/IMP) P39927 (/IMP) P39927 (/IMP) P39927 (/IMP) P39927 (/IMP)

There are 4 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
8 P39927 (/HDA) P39927 (/HDA) P39927 (/HDA) P39927 (/HDA) P39927 (/HDA) P39927 (/HDA) P39927 (/HDA) P39927 (/HDA)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
8 P39927 (/IDA) P39927 (/IDA) P39927 (/IDA) P39927 (/IDA) P39927 (/IDA) P39927 (/IDA) P39927 (/IDA) P39927 (/IDA)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
8 P39927 (/IDA) P39927 (/IDA) P39927 (/IDA) P39927 (/IDA) P39927 (/IDA) P39927 (/IDA) P39927 (/IDA) P39927 (/IDA)
MRNA cleavage and polyadenylation specificity factor complex GO:0005847
A multisubunit complex that binds to the canonical AAUAAA hexamer and to U-rich upstream sequence elements on the pre-mRNA, thereby stimulating the otherwise weakly active and nonspecific polymerase to elongate efficiently RNAs containing a poly(A) signal.
8 P39927 (/IDA) P39927 (/IDA) P39927 (/IDA) P39927 (/IDA) P39927 (/IDA) P39927 (/IDA) P39927 (/IDA) P39927 (/IDA)
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