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CATH Superfamily 1.10.1600.10

The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
SC:1X-ray repair cross-complementing protein 6 isoform X2X-ray repair cross-complementing protein 5ATP-dependent DNA helicase 2 subunit KU70ATP-dependent DNA helicase II subunit 1ATP-dependent DNA helicase II subunit 1ATP-dependent DNA helicase 2 subunit 2Yeast Ku70 proteinATP-dependent DNA helicase II subunit 2ATP-dependent DNA helicase II subunit 2Inverted repeat-binding proteinCaenorhabditis KUAGAP002690-PAUncharacterized proteinPredicted proteinUncharacterized proteinATP-dependent DNA helicase 2 subunit KU80Uncharacterized proteinATP-dependent DNA helicase ku70DNA binding proteinPotential Ku DNA binding protein subunitPutative dna-binding subunit of a dna-dependent protein kinase ku70 autoantigenATP-dependent DNA helicase II subunit 1Cku-70X-ray repair cross-complementing protein 5Uncharacterized proteinKu70-like proteinATP-dependent DNA helicase II subunit 1Uncharacterized proteinATP-dependent DNA helicasePredicted proteinPredicted proteinDNA binding proteinUncharacterized proteinATP dependent DNA ligase 1Uncharacterized proteinKU70 proteinInverted repeat-binding proteinUncharacterized proteinPutative KU70 protein
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FunFam 10: Inverted repeat-binding protein

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 4 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO TermAnnotationsEvidence
DNA binding GO:0003677
Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
 2 Q23976 (/IDA) Q23976 (/IDA)
DNA binding GO:0003677
Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
 2 Q23976 (/ISS) Q23976 (/ISS)
Protein heterodimerization activity GO:0046982
Interacting selectively and non-covalently with a nonidentical protein to form a heterodimer.
 2 Q23976 (/IDA) Q23976 (/IDA)
5'-deoxyribose-5-phosphate lyase activity GO:0051575
Catalysis of the beta-elimination of the 5' deoxyribose-5-phosphate at an abasic site in DNA where a DNA-(apurinic or apyrimidinic site) lyase has already cleaved the C-O-P bond 3' to the apurinic or apyrimidinic site.
 2 Q23976 (/ISS) Q23976 (/ISS)
Showing 1 to 4 of 4 entries

There are 2 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO TermAnnotationsEvidence
Telomere maintenance GO:0000723
Any process that contributes to the maintenance of proper telomeric length and structure by affecting and monitoring the activity of telomeric proteins, the length of telomeric DNA and the replication and repair of the DNA. These processes includes those that shorten, lengthen, replicate and repair the telomeric DNA sequences.
 2 Q23976 (/IMP) Q23976 (/IMP)
Double-strand break repair via nonhomologous end joining GO:0006303
The repair of a double-strand break in DNA in which the two broken ends are rejoined with little or no sequence complementarity. Information at the DNA ends may be lost due to the modification of broken DNA ends. This term covers instances of separate pathways, called classical (or canonical) and alternative nonhomologous end joining (C-NHEJ and A-NHEJ). These in turn may further branch into sub-pathways, but evidence is still unclear.
 2 Q23976 (/IMP) Q23976 (/IMP)
Showing 1 to 2 of 2 entries

There are 1 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO TermAnnotationsEvidence
Ku70:Ku80 complex GO:0043564
Heterodimeric protein complex composed of a 70 kDa and a 80 kDa subunit, binds DNA through a channel formed by the heterodimer. Functions in DNA double stranded break repair, chromosome maintenance, transcription regulation, V(D)J recombination, and activation of DNA-PK.
 2 Q23976 (/IDA) Q23976 (/IDA)
Showing 1 to 1 of 1 entries
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