The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:
"Transcription Factor, Ets-1
".
FunFam 45: SAM domain, SH3 domain and nuclear localization si...
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 3 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Phosphotyrosine residue binding GO:0001784
Interacting selectively and non-covalently with a phosphorylated tyrosine residue within a protein.
|
2 | P57725 (/ISO) P57725 (/ISO) |
|
Phosphotyrosine residue binding GO:0001784
Interacting selectively and non-covalently with a phosphorylated tyrosine residue within a protein.
|
1 | Q9NSI8 (/IDA) |
|
RNA binding GO:0003723
Interacting selectively and non-covalently with an RNA molecule or a portion thereof.
|
1 | Q9NSI8 (/HDA) |
There are 6 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Negative regulation of adaptive immune response GO:0002820
Any process that stops, prevents, or reduces the frequency, rate, or extent of an adaptive immune response.
|
2 | P57725 (/IMP) P57725 (/IMP) |
|
Negative regulation of peptidyl-tyrosine phosphorylation GO:0050732
Any process that stops, prevents, or reduces the frequency, rate or extent of the phosphorylation of peptidyl-tyrosine.
|
2 | P57725 (/IMP) P57725 (/IMP) |
|
Negative regulation of B cell activation GO:0050869
Any process that stops, prevents, or reduces the frequency, rate or extent of B cell activation.
|
2 | P57725 (/IMP) P57725 (/IMP) |
|
Negative regulation of adaptive immune response GO:0002820
Any process that stops, prevents, or reduces the frequency, rate, or extent of an adaptive immune response.
|
1 | Q9NSI8 (/ISS) |
|
Negative regulation of peptidyl-tyrosine phosphorylation GO:0050732
Any process that stops, prevents, or reduces the frequency, rate or extent of the phosphorylation of peptidyl-tyrosine.
|
1 | Q9NSI8 (/ISS) |
|
Negative regulation of B cell activation GO:0050869
Any process that stops, prevents, or reduces the frequency, rate or extent of B cell activation.
|
1 | Q9NSI8 (/ISS) |
There are 6 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
3 | P57725 (/IDA) P57725 (/IDA) Q9NSI8 (/IDA) |
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
2 | P57725 (/ISO) P57725 (/ISO) |
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
2 | P57725 (/ISO) P57725 (/ISO) |
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
2 | P57725 (/IDA) P57725 (/IDA) |
|
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
2 | Q9NSI8 (/IDA) S6FRS6 (/IDA) |
|
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
2 | P57725 (/ISO) P57725 (/ISO) |
