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CATH Superfamily 1.10.1280.10

Di-copper center containing domain from catechol oxidase

The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:

"
Di-copper center containing domain from catechol oxidase
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 19: Grixazone synthase

There are 2 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Grixazone synthase. [EC: 1.10.3.15]
2 3-amino-4-hydroxybenzoate + N-acetyl-L-cysteine + 2 O(2) = grixazone B + 4 H(2)O + CO(2).
  • The enzyme, isolated from the bacterium Streptomyces griseus, catalyzes an 8 electron oxidation.
  • Activation of the enzyme requires a copper chaperone (GriE).
  • It also acts on 3-amino-4-hydroxybenzaldehyde, giving grixazone A.
  • The second aldehyde group is presumably lost as formate.
  • The enzyme also catalyzes the reaction of EC 1.10.3.4.
 4 A0A2X2MDW3 A0A2X2MDW3 B1VTI5 B1VTI5
O-aminophenol oxidase. [EC: 1.10.3.4]
4 2-aminophenol + 3 O(2) = 2 2-aminophenoxazin-3-one + 6 H(2)O.
    		 4 A0A2X2MDW3 A0A2X2MDW3 B1VTI5 B1VTI5
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