The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:
"Homeodomain-like
".
FunFam 46: SIX homeobox 3
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 22 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
9 | O95343 (/IPI) O95343 (/IPI) O95343 (/IPI) Q62233 (/IPI) Q94165 (/IPI) Q9ET75 (/IPI) Q9QZ28 (/IPI) Q9QZ28 (/IPI) Q9QZ28 (/IPI) |
|
DNA-binding transcription factor activity GO:0003700
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons.
|
7 | O42406 (/ISS) O42406 (/ISS) O73916 (/ISS) O95343 (/ISS) O95343 (/ISS) O95343 (/ISS) Q23175 (/ISS) |
|
DNA-binding transcription factor activity, RNA polymerase II-specific GO:0000981
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.
|
6 | O95343 (/ISA) O95343 (/ISA) O95343 (/ISA) O95475 (/ISA) O95475 (/ISA) O95475 (/ISA) |
|
DNA-binding transcription factor activity, RNA polymerase II-specific GO:0000981
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.
|
6 | O95343 (/ISM) O95343 (/ISM) O95343 (/ISM) O95475 (/ISM) O95475 (/ISM) O95475 (/ISM) |
|
DNA-binding transcription factor activity, RNA polymerase II-specific GO:0000981
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.
|
6 | O95343 (/NAS) O95343 (/NAS) O95343 (/NAS) O95475 (/NAS) O95475 (/NAS) O95475 (/NAS) |
|
Transcription coactivator activity GO:0003713
A protein or a member of a complex that interacts specifically and non-covalently with a DNA-bound DNA-binding transcription factor to activate the transcription of specific genes. Coactivators often act by altering chromatin structure and modifications. For example, one class of transcription coregulators modifies chromatin structure through covalent modification of histones. A second ATP-dependent class modifies the conformation of chromatin. Another type of coregulator activity is the bridging of a DNA-binding transcription factor to the basal transcription machinery. The Mediator complex, which bridges transcription factors and RNA polymerase, is also a transcription coactivator.
|
6 | O42406 (/ISS) O42406 (/ISS) O73916 (/ISS) O95343 (/ISS) O95343 (/ISS) O95343 (/ISS) |
|
Transcription corepressor binding GO:0001222
Interacting selectively and non-covalently with a transcription corepressor, any protein involved in negative regulation of transcription via protein-protein interactions with transcription factors and other proteins that negatively regulate transcription. Transcription corepressors do not bind DNA directly, but rather mediate protein-protein interactions between repressing transcription factors and the basal transcription machinery.
|
5 | O73916 (/IPI) O95343 (/IPI) O95343 (/IPI) O95343 (/IPI) Q62233 (/IPI) |
|
DNA-binding transcription activator activity, RNA polymerase II-specific GO:0001228
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to activate or increase transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.
|
4 | Q62233 (/IDA) Q9QZ28 (/IDA) Q9QZ28 (/IDA) Q9QZ28 (/IDA) |
|
Signaling receptor binding GO:0005102
Interacting selectively and non-covalently with one or more specific sites on a receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function.
|
3 | A0A0G2JWI0 (/IMP) A0A0G2K2C0 (/IMP) Q9ET75 (/IMP) |
|
Sequence-specific DNA binding GO:0043565
Interacting selectively and non-covalently with DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding.
|
3 | Q62233 (/IDA) Q94165 (/IDA) Q95RW8 (/IDA) |
|
Sequence-specific double-stranded DNA binding GO:1990837
Interacting selectively and non-covalently with double-stranded DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA, e.g. promotor binding or rDNA binding.
|
3 | Q9QZ28 (/IDA) Q9QZ28 (/IDA) Q9QZ28 (/IDA) |
|
DNA-binding transcription factor activity, RNA polymerase II-specific GO:0000981
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.
|
2 | O42406 (/ISS) O42406 (/ISS) |
|
DNA binding GO:0003677
Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
|
2 | O42406 (/ISS) O42406 (/ISS) |
|
RNA polymerase II distal enhancer sequence-specific DNA binding GO:0000980
Interacting selectively and non-covalently with a RNA polymerase II (Pol II) distal enhancer. In mammalian cells, enhancers are distal sequences that increase the utilization of some promoters, and can function in either orientation and in any location (upstream or downstream) relative to the core promoter.
|
1 | Q62233 (/IDA) |
|
DNA-binding transcription factor activity, RNA polymerase II-specific GO:0000981
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.
|
1 | Q62233 (/IDA) |
|
DNA-binding transcription factor activity, RNA polymerase II-specific GO:0000981
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.
|
1 | O93282 (/TAS) |
|
Transcription corepressor binding GO:0001222
Interacting selectively and non-covalently with a transcription corepressor, any protein involved in negative regulation of transcription via protein-protein interactions with transcription factors and other proteins that negatively regulate transcription. Transcription corepressors do not bind DNA directly, but rather mediate protein-protein interactions between repressing transcription factors and the basal transcription machinery.
|
1 | Q62233 (/ISO) |
|
DNA binding GO:0003677
Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
|
1 | Q62233 (/IDA) |
|
DNA-binding transcription factor activity GO:0003700
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons.
|
1 | Q62233 (/IDA) |
|
Transcription coactivator activity GO:0003713
A protein or a member of a complex that interacts specifically and non-covalently with a DNA-bound DNA-binding transcription factor to activate the transcription of specific genes. Coactivators often act by altering chromatin structure and modifications. For example, one class of transcription coregulators modifies chromatin structure through covalent modification of histones. A second ATP-dependent class modifies the conformation of chromatin. Another type of coregulator activity is the bridging of a DNA-binding transcription factor to the basal transcription machinery. The Mediator complex, which bridges transcription factors and RNA polymerase, is also a transcription coactivator.
|
1 | Q62233 (/IDA) |
|
Signaling receptor binding GO:0005102
Interacting selectively and non-covalently with one or more specific sites on a receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function.
|
1 | Q62233 (/ISO) |
|
Histone deacetylase binding GO:0042826
Interacting selectively and non-covalently with the enzyme histone deacetylase.
|
1 | Q62233 (/IPI) |
There are 85 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Epithelial cell maturation GO:0002070
The developmental process, independent of morphogenetic (shape) change, that is required for an epithelial cell to attain its fully functional state. An epithelial cell is a cell usually found in a two-dimensional sheet with a free surface.
|
6 | O42406 (/ISS) O42406 (/ISS) O73916 (/ISS) O95343 (/ISS) O95343 (/ISS) O95343 (/ISS) |
|
Lens development in camera-type eye GO:0002088
The process whose specific outcome is the progression of the lens over time, from its formation to the mature structure. The lens is a transparent structure in the eye through which light is focused onto the retina. An example of this process is found in Mus musculus.
|
6 | O42406 (/ISS) O42406 (/ISS) O73916 (/ISS) O95343 (/ISS) O95343 (/ISS) O95343 (/ISS) |
|
Optic vesicle morphogenesis GO:0003404
The developmental process pertaining to the formation and shaping of the optic vesicle. This process begins with the specific processes that contribute to the appearance of the vesicle and ends when the vesicle has evaginated. The optic vesicle is the evagination of neurectoderm that precedes formation of the optic cup.
|
6 | O42406 (/ISS) O42406 (/ISS) O73916 (/ISS) O95343 (/ISS) O95343 (/ISS) O95343 (/ISS) |
|
Visual perception GO:0007601
The series of events required for an organism to receive a visual stimulus, convert it to a molecular signal, and recognize and characterize the signal. Visual stimuli are detected in the form of photons and are processed to form an image.
|
6 | O95343 (/TAS) O95343 (/TAS) O95343 (/TAS) O95475 (/TAS) O95475 (/TAS) O95475 (/TAS) |
|
Proximal/distal axis specification GO:0009946
The establishment, maintenance and elaboration of the proximal/distal axis. The proximal/distal axis is defined by a line that runs from main body (proximal end) of an organism outward (distal end).
|
6 | O42406 (/ISS) O42406 (/ISS) O73916 (/ISS) O95343 (/ISS) O95343 (/ISS) O95343 (/ISS) |
|
Neuroblast differentiation GO:0014016
The process in which a relatively unspecialized cell acquires specialized features of a neuroblast. There are at least four stages through which the pluripotent cells of epiblast or blastula become neuroblasts.
|
6 | O42406 (/ISS) O42406 (/ISS) O73916 (/ISS) O95343 (/ISS) O95343 (/ISS) O95343 (/ISS) |
|
Telencephalon development GO:0021537
The process whose specific outcome is the progression of the telencephalon over time, from its formation to the mature structure. The telencephalon is the paired anteriolateral division of the prosencephalon plus the lamina terminalis from which the olfactory lobes, cerebral cortex, and subcortical nuclei are derived.
|
6 | O42406 (/ISS) O42406 (/ISS) O73916 (/ISS) O95343 (/ISS) O95343 (/ISS) O95343 (/ISS) |
|
Cell proliferation in forebrain GO:0021846
The creation of greater cell numbers in the forebrain due to cell division of progenitor cells.
|
6 | O42406 (/ISS) O42406 (/ISS) O73916 (/ISS) O95343 (/ISS) O95343 (/ISS) O95343 (/ISS) |
|
Telencephalon regionalization GO:0021978
The regionalization process that creates areas within the forebrain that will direct the behavior of cell migration in differentiation as the telencephalon develops.
|
6 | O42406 (/ISS) O42406 (/ISS) O73916 (/ISS) O95343 (/ISS) O95343 (/ISS) O95343 (/ISS) |
|
Pituitary gland development GO:0021983
The progression of the pituitary gland over time from its initial formation until its mature state. The pituitary gland is an endocrine gland that secretes hormones that regulate many other glands.
|
6 | O42406 (/ISS) O42406 (/ISS) O73916 (/ISS) O95343 (/ISS) O95343 (/ISS) O95343 (/ISS) |
|
Regulation of cell population proliferation GO:0042127
Any process that modulates the frequency, rate or extent of cell proliferation.
|
6 | O42406 (/ISS) O42406 (/ISS) O73916 (/ISS) O95343 (/ISS) O95343 (/ISS) O95343 (/ISS) |
|
Negative regulation of neuron differentiation GO:0045665
Any process that stops, prevents, or reduces the frequency, rate or extent of neuron differentiation.
|
6 | O42406 (/ISS) O42406 (/ISS) O73916 (/ISS) O95343 (/ISS) O95343 (/ISS) O95343 (/ISS) |
|
Regulation of neural retina development GO:0061074
Any process that modulates the rate, frequency, or extent of neural retina development, the progression of the neural retina over time from its initial formation to the mature structure. The neural retina is the part of the retina that contains neurons and photoreceptor cells.
|
6 | O42406 (/ISS) O42406 (/ISS) O73916 (/ISS) O95343 (/ISS) O95343 (/ISS) O95343 (/ISS) |
|
Lens fiber cell differentiation GO:0070306
The process in which a relatively unspecialized cell acquires specialized features of a lens fiber cell, any of the elongated, tightly packed cells that make up the bulk of the mature lens in the camera-type eye. The cytoplasm of a lens fiber cell is devoid of most intracellular organelles including the cell nucleus, and contains primarily crystallins, a group of water-soluble proteins expressed in vary large quantities.
|
6 | O42406 (/ISS) O42406 (/ISS) O73916 (/ISS) O95343 (/ISS) O95343 (/ISS) O95343 (/ISS) |
|
Neuroblast migration GO:0097402
The orderly movement of a neuroblast from one site to another, often during the development of a multicellular organism or multicellular structure. A neuroblast is any cell that will divide and give rise to a neuron.
|
6 | O42406 (/ISS) O42406 (/ISS) O73916 (/ISS) O95343 (/ISS) O95343 (/ISS) O95343 (/ISS) |
|
Regulation of cell cycle phase transition GO:1901987
Any process that modulates the frequency, rate or extent of cell cycle phase transition.
|
6 | O42406 (/ISS) O42406 (/ISS) O73916 (/ISS) O95343 (/ISS) O95343 (/ISS) O95343 (/ISS) |
|
Regulation of neuroblast proliferation GO:1902692
Any process that modulates the frequency, rate or extent of neuroblast proliferation.
|
6 | O42406 (/ISS) O42406 (/ISS) O73916 (/ISS) O95343 (/ISS) O95343 (/ISS) O95343 (/ISS) |
|
Apoptotic process involved in development GO:1902742
Any apoptotic process that is involved in anatomical structure development.
|
6 | O42406 (/ISS) O42406 (/ISS) O73916 (/ISS) O95343 (/ISS) O95343 (/ISS) O95343 (/ISS) |
|
Lens fiber cell apoptotic process GO:1990086
Any apoptotic process in a lens fiber cell. Lens fiber cells are elongated, tightly packed cells that make up the bulk of the mature lens in a camera-type eye.
|
6 | O42406 (/ISS) O42406 (/ISS) O73916 (/ISS) O95343 (/ISS) O95343 (/ISS) O95343 (/ISS) |
|
Regulation of neural precursor cell proliferation GO:2000177
Any process that modulates the frequency, rate or extent of neural precursor cell proliferation.
|
6 | O42406 (/ISS) O42406 (/ISS) O73916 (/ISS) O95343 (/ISS) O95343 (/ISS) O95343 (/ISS) |
|
Brain development GO:0007420
The process whose specific outcome is the progression of the brain over time, from its formation to the mature structure. Brain development begins with patterning events in the neural tube and ends with the mature structure that is the center of thought and emotion. The brain is responsible for the coordination and control of bodily activities and the interpretation of information from the senses (sight, hearing, smell, etc.).
|
5 | O73708 (/IMP) O73709 (/IMP) Q62233 (/IMP) Q6PCA5 (/IMP) Q6PCA5 (/IMP) |
|
Eye development GO:0001654
The process whose specific outcome is the progression of the eye over time, from its formation to the mature structure. The eye is the organ of sight.
|
4 | O95343 (/IDA) O95343 (/IDA) O95343 (/IDA) Q62233 (/IDA) |
|
Optic nerve development GO:0021554
The process whose specific outcome is the progression of the optic nerve over time, from its formation to the mature structure. The sensory optic nerve originates from the bipolar cells of the retina and conducts visual information to the brainstem. The optic nerve exits the back of the eye in the orbit, enters the optic canal, and enters the central nervous system at the optic chiasm (crossing) where the nerve fibers become the optic tract just prior to entering the hindbrain.
|
4 | O73708 (/IGI) O73709 (/IGI) Q6PCA5 (/IGI) Q6PCA5 (/IGI) |
|
Optic nerve morphogenesis GO:0021631
The process in which the anatomical structure of the optic nerve is generated and organized. The sensory optic nerve originates from the bipolar cells of the retina and conducts visual information to the brainstem. The optic nerve exits the back of the eye in the orbit, enters the optic canal, and enters the central nervous system at the optic chiasm (crossing) where the nerve fibers become the optic tract just prior to entering the hindbrain.
|
4 | O73708 (/IGI) O73709 (/IGI) Q6PCA5 (/IGI) Q6PCA5 (/IGI) |
|
Forebrain dorsal/ventral pattern formation GO:0021798
The formation of specific regional progenitor domains along the dorsal-ventral axis in the developing forebrain.
|
4 | O42406 (/ISS) O42406 (/ISS) O73916 (/ISS) Q62233 (/ISS) |
|
Negative regulation of transcription, DNA-templated GO:0045892
Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription.
|
4 | O95343 (/IDA) O95343 (/IDA) O95343 (/IDA) Q62233 (/IDA) |
|
Eye development GO:0001654
The process whose specific outcome is the progression of the eye over time, from its formation to the mature structure. The eye is the organ of sight.
|
3 | O42406 (/ISS) O42406 (/ISS) O73916 (/ISS) |
|
Brain development GO:0007420
The process whose specific outcome is the progression of the brain over time, from its formation to the mature structure. Brain development begins with patterning events in the neural tube and ends with the mature structure that is the center of thought and emotion. The brain is responsible for the coordination and control of bodily activities and the interpretation of information from the senses (sight, hearing, smell, etc.).
|
3 | O95343 (/TAS) O95343 (/TAS) O95343 (/TAS) |
|
Animal organ morphogenesis GO:0009887
Morphogenesis of an animal organ. An organ is defined as a tissue or set of tissues that work together to perform a specific function or functions. Morphogenesis is the process in which anatomical structures are generated and organized. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions.
|
3 | O95475 (/TAS) O95475 (/TAS) O95475 (/TAS) |
|
Forebrain dorsal/ventral pattern formation GO:0021798
The formation of specific regional progenitor domains along the dorsal-ventral axis in the developing forebrain.
|
3 | O95343 (/IDA) O95343 (/IDA) O95343 (/IDA) |
|
Negative regulation of transcription, DNA-templated GO:0045892
Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription.
|
3 | A0A0G2JWI0 (/IMP) A0A0G2K2C0 (/IMP) Q9ET75 (/IMP) |
|
Negative regulation of transcription, DNA-templated GO:0045892
Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription.
|
3 | O42406 (/ISS) O42406 (/ISS) O73916 (/ISS) |
|
Eye development GO:0001654
The process whose specific outcome is the progression of the eye over time, from its formation to the mature structure. The eye is the organ of sight.
|
2 | O73709 (/IGI) O93282 (/IGI) |
|
Compound eye photoreceptor cell differentiation GO:0001751
The process in which a relatively unspecialized cell acquires the specialized features of an eye photoreceptor cell.
|
2 | O93282 (/IMP) Q95RW8 (/IMP) |
|
Brain development GO:0007420
The process whose specific outcome is the progression of the brain over time, from its formation to the mature structure. Brain development begins with patterning events in the neural tube and ends with the mature structure that is the center of thought and emotion. The brain is responsible for the coordination and control of bodily activities and the interpretation of information from the senses (sight, hearing, smell, etc.).
|
2 | O42406 (/ISS) O42406 (/ISS) |
|
Negative regulation of Wnt signaling pathway GO:0030178
Any process that stops, prevents, or reduces the frequency, rate or extent of the Wnt signaling pathway.
|
2 | O42406 (/ISS) O42406 (/ISS) |
|
Embryonic camera-type eye morphogenesis GO:0048596
The process in which the anatomical structures of the eye are generated and organized during embryonic development.
|
2 | O73709 (/IGI) O93282 (/IGI) |
|
Eye development GO:0001654
The process whose specific outcome is the progression of the eye over time, from its formation to the mature structure. The eye is the organ of sight.
|
1 | Q5TYZ2 (/IMP) |
|
Eye development GO:0001654
The process whose specific outcome is the progression of the eye over time, from its formation to the mature structure. The eye is the organ of sight.
|
1 | Q62233 (/ISO) |
|
Compound eye morphogenesis GO:0001745
The morphogenetic process in which the anatomical structures of the compound eye are generated and organized. The adult compound eye is a precise assembly of 700-800 ommatidia. Each ommatidium is composed of 20 cells, identified by cell type and position. An example of compound eye morphogenesis is found in Drosophila melanogaster.
|
1 | Q95RW8 (/IMP) |
|
Epithelial cell maturation GO:0002070
The developmental process, independent of morphogenetic (shape) change, that is required for an epithelial cell to attain its fully functional state. An epithelial cell is a cell usually found in a two-dimensional sheet with a free surface.
|
1 | Q62233 (/IMP) |
|
Lens development in camera-type eye GO:0002088
The process whose specific outcome is the progression of the lens over time, from its formation to the mature structure. The lens is a transparent structure in the eye through which light is focused onto the retina. An example of this process is found in Mus musculus.
|
1 | Q62233 (/IDA) |
|
Optic vesicle morphogenesis GO:0003404
The developmental process pertaining to the formation and shaping of the optic vesicle. This process begins with the specific processes that contribute to the appearance of the vesicle and ends when the vesicle has evaginated. The optic vesicle is the evagination of neurectoderm that precedes formation of the optic cup.
|
1 | Q62233 (/IDA) |
|
Neural retina development GO:0003407
The progression of the neural retina over time from its initial formation to the mature structure. The neural retina is the part of the retina that contains neurons and photoreceptor cells.
|
1 | Q7T3G8 (/IMP) |
|
Regulation of transcription, DNA-templated GO:0006355
Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.
|
1 | Q94165 (/IMP) |
|
Regulation of transcription, DNA-templated GO:0006355
Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.
|
1 | Q23175 (/TAS) |
|
Regulation of transcription by RNA polymerase II GO:0006357
Any process that modulates the frequency, rate or extent of transcription mediated by RNA polymerase II.
|
1 | O93282 (/TAS) |
|
Protein import into nucleus GO:0006606
The directed movement of a protein from the cytoplasm to the nucleus.
|
1 | Q62233 (/IDA) |
|
Progression of morphogenetic furrow involved in compound eye morphogenesis GO:0007458
The morphogenetic furrow is a dorsoventral indentation which sweeps anteriorly across the eye disc. Ommatidia begin to form along the furrow, resulting in a graded series of ommatidial development across the anterior/posterior axis of the disc.
|
1 | Q95RW8 (/IMP) |
|
Mesodermal cell fate specification GO:0007501
The cell fate determination process in which a cell becomes capable of differentiating autonomously into a mesoderm cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed.
|
1 | Q94165 (/IMP) |
|
Post-embryonic animal morphogenesis GO:0009886
The process, occurring after animal embryonic development, by which anatomical structures are generated and organized.
|
1 | Q23175 (/IMP) |
|
Proximal/distal axis specification GO:0009946
The establishment, maintenance and elaboration of the proximal/distal axis. The proximal/distal axis is defined by a line that runs from main body (proximal end) of an organism outward (distal end).
|
1 | Q62233 (/IDA) |
|
Neuroblast differentiation GO:0014016
The process in which a relatively unspecialized cell acquires specialized features of a neuroblast. There are at least four stages through which the pluripotent cells of epiblast or blastula become neuroblasts.
|
1 | Q62233 (/IMP) |
|
Diencephalon development GO:0021536
The process whose specific outcome is the progression of the diencephalon over time, from its formation to the mature structure. The diencephalon is the paired caudal parts of the prosencephalon from which the thalamus, hypothalamus, epithalamus and subthalamus are derived; these regions regulate autonomic, visceral and endocrine function, and process information directed to the cerebral cortex.
|
1 | Q62233 (/IGI) |
|
Telencephalon development GO:0021537
The process whose specific outcome is the progression of the telencephalon over time, from its formation to the mature structure. The telencephalon is the paired anteriolateral division of the prosencephalon plus the lamina terminalis from which the olfactory lobes, cerebral cortex, and subcortical nuclei are derived.
|
1 | Q62233 (/IMP) |
|
Forebrain anterior/posterior pattern specification GO:0021797
The creation of specific areas of progenitor domains along the anterior-posterior axis of the developing forebrain.
|
1 | Q62233 (/IGI) |
|
Forebrain anterior/posterior pattern specification GO:0021797
The creation of specific areas of progenitor domains along the anterior-posterior axis of the developing forebrain.
|
1 | Q62233 (/IMP) |
|
Forebrain dorsal/ventral pattern formation GO:0021798
The formation of specific regional progenitor domains along the dorsal-ventral axis in the developing forebrain.
|
1 | Q62233 (/ISO) |
|
Cell proliferation in forebrain GO:0021846
The creation of greater cell numbers in the forebrain due to cell division of progenitor cells.
|
1 | Q62233 (/IMP) |
|
Telencephalon regionalization GO:0021978
The regionalization process that creates areas within the forebrain that will direct the behavior of cell migration in differentiation as the telencephalon develops.
|
1 | Q62233 (/IMP) |
|
Pituitary gland development GO:0021983
The progression of the pituitary gland over time from its initial formation until its mature state. The pituitary gland is an endocrine gland that secretes hormones that regulate many other glands.
|
1 | Q62233 (/IMP) |
|
Negative regulation of Wnt signaling pathway GO:0030178
Any process that stops, prevents, or reduces the frequency, rate or extent of the Wnt signaling pathway.
|
1 | Q62233 (/IMP) |
|
Cell proliferation involved in compound eye morphogenesis GO:0035736
The multiplication or reproduction of cells, resulting in the expansion of a cell population that contributes to compound eye morphogenesis.
|
1 | Q5TYZ2 (/IMP) |
|
Regulation of cell population proliferation GO:0042127
Any process that modulates the frequency, rate or extent of cell proliferation.
|
1 | Q62233 (/IMP) |
|
Camera-type eye development GO:0043010
The process whose specific outcome is the progression of the camera-type eye over time, from its formation to the mature structure. The camera-type eye is an organ of sight that receives light through an aperture and focuses it through a lens, projecting it on a photoreceptor field.
|
1 | Q62233 (/IGI) |
|
Negative regulation of neuron differentiation GO:0045665
Any process that stops, prevents, or reduces the frequency, rate or extent of neuron differentiation.
|
1 | Q62233 (/IDA) |
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Negative regulation of transcription, DNA-templated GO:0045892
Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription.
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1 | Q62233 (/ISO) |
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Positive regulation of transcription by RNA polymerase II GO:0045944
Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
|
1 | Q62233 (/IDA) |
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Retinal cone cell development GO:0046549
Development of a cone cell, one of the sensory cells in the eye that reacts to the presence of light. Cone cells contain the photopigment iodopsin or cyanopsin and are responsible for photopic (daylight) vision.
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1 | O93282 (/IMP) |
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Circadian behavior GO:0048512
The specific behavior of an organism that recurs with a regularity of approximately 24 hours.
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1 | Q62233 (/IMP) |
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Compound eye development GO:0048749
The process whose specific outcome is the progression of the compound eye over time, from its formation to the mature structure. The compound eye is an organ of sight that contains multiple repeating units, often arranged hexagonally. Each unit has its own lens and photoreceptor cell(s) and can generate either a single pixelated image or multiple images, per eye.
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1 | Q95RW8 (/IEP) |
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Compound eye development GO:0048749
The process whose specific outcome is the progression of the compound eye over time, from its formation to the mature structure. The compound eye is an organ of sight that contains multiple repeating units, often arranged hexagonally. Each unit has its own lens and photoreceptor cell(s) and can generate either a single pixelated image or multiple images, per eye.
|
1 | Q95RW8 (/IMP) |
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Compound eye development GO:0048749
The process whose specific outcome is the progression of the compound eye over time, from its formation to the mature structure. The compound eye is an organ of sight that contains multiple repeating units, often arranged hexagonally. Each unit has its own lens and photoreceptor cell(s) and can generate either a single pixelated image or multiple images, per eye.
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1 | Q95RW8 (/NAS) |
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Dendrite morphogenesis GO:0048813
The process in which the anatomical structures of a dendrite are generated and organized.
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1 | Q95RW8 (/IMP) |
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Lens induction in camera-type eye GO:0060235
Signaling at short range between the head ectoderm and the optic vesicle that results in the head ectoderm forming a lens.
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1 | Q62233 (/IMP) |
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Regulation of neural retina development GO:0061074
Any process that modulates the rate, frequency, or extent of neural retina development, the progression of the neural retina over time from its initial formation to the mature structure. The neural retina is the part of the retina that contains neurons and photoreceptor cells.
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1 | Q62233 (/IMP) |
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Lens fiber cell differentiation GO:0070306
The process in which a relatively unspecialized cell acquires specialized features of a lens fiber cell, any of the elongated, tightly packed cells that make up the bulk of the mature lens in the camera-type eye. The cytoplasm of a lens fiber cell is devoid of most intracellular organelles including the cell nucleus, and contains primarily crystallins, a group of water-soluble proteins expressed in vary large quantities.
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1 | Q62233 (/IDA) |
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Sensory epithelium regeneration GO:0070654
The regrowth of a sensory epithelium following its loss or destruction.
|
1 | O73709 (/IGI) |
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Neuroblast migration GO:0097402
The orderly movement of a neuroblast from one site to another, often during the development of a multicellular organism or multicellular structure. A neuroblast is any cell that will divide and give rise to a neuron.
|
1 | Q62233 (/IMP) |
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Regulation of cell cycle phase transition GO:1901987
Any process that modulates the frequency, rate or extent of cell cycle phase transition.
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1 | Q62233 (/IDA) |
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Regulation of neuroblast proliferation GO:1902692
Any process that modulates the frequency, rate or extent of neuroblast proliferation.
|
1 | Q62233 (/IMP) |
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Apoptotic process involved in development GO:1902742
Any apoptotic process that is involved in anatomical structure development.
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1 | Q62233 (/IMP) |
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Positive regulation of apoptotic process involved in development GO:1904747
Any process that activates or increases the frequency, rate or extent of apoptotic process involved in development.
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1 | Q94165 (/IMP) |
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Lens fiber cell apoptotic process GO:1990086
Any apoptotic process in a lens fiber cell. Lens fiber cells are elongated, tightly packed cells that make up the bulk of the mature lens in a camera-type eye.
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1 | Q62233 (/IDA) |
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Regulation of neural precursor cell proliferation GO:2000177
Any process that modulates the frequency, rate or extent of neural precursor cell proliferation.
|
1 | Q62233 (/IDA) |
There are 2 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
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6 | Q23175 (/IDA) Q62233 (/IDA) Q94165 (/IDA) Q9QZ28 (/IDA) Q9QZ28 (/IDA) Q9QZ28 (/IDA) |
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Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
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2 | O42406 (/ISS) O42406 (/ISS) |
