The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:
"Homeodomain-like
".
FunFam 25: Mesoderm induction early response 1, transcription...
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 6 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
DNA-binding transcription factor activity, RNA polymerase II-specific GO:0000981
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.
|
5 | Q7Z3K6 (/ISA) Q7Z3K6 (/ISA) Q8N108 (/ISA) Q8N108 (/ISA) Q8N344 (/ISA) |
|
DNA-binding transcription factor activity, RNA polymerase II-specific GO:0000981
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.
|
4 | Q7Z3K6 (/ISM) Q7Z3K6 (/ISM) Q8N108 (/ISM) Q8N108 (/ISM) |
|
Histone deacetylase binding GO:0042826
Interacting selectively and non-covalently with the enzyme histone deacetylase.
|
3 | Q8N108 (/IPI) Q8N108 (/IPI) Q8N344 (/IPI) |
|
Histone deacetylase binding GO:0042826
Interacting selectively and non-covalently with the enzyme histone deacetylase.
|
3 | Q3U3N0 (/ISO) Q5UAK0 (/ISO) Q5UAK0 (/ISO) |
|
DNA-binding transcription factor activity, RNA polymerase II-specific GO:0000981
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.
|
2 | Q8N108 (/NAS) Q8N108 (/NAS) |
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
2 | Q8N108 (/IPI) Q8N108 (/IPI) |
There are 6 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Positive regulation of chromatin silencing GO:0031937
Any process that activates or increases the frequency, rate or extent of chromatin silencing.
|
6 | Q5REE1 (/ISS) Q5REE1 (/ISS) Q5UAK0 (/ISS) Q5UAK0 (/ISS) Q5ZKT9 (/ISS) Q7T105 (/ISS) |
|
Histone deacetylation GO:0016575
The modification of histones by removal of acetyl groups.
|
3 | Q8N108 (/IDA) Q8N108 (/IDA) Q8N344 (/IDA) |
|
Histone deacetylation GO:0016575
The modification of histones by removal of acetyl groups.
|
3 | Q3U3N0 (/ISO) Q5UAK0 (/ISO) Q5UAK0 (/ISO) |
|
Positive regulation of chromatin silencing GO:0031937
Any process that activates or increases the frequency, rate or extent of chromatin silencing.
|
2 | Q8N108 (/IDA) Q8N108 (/IDA) |
|
Positive regulation of chromatin silencing GO:0031937
Any process that activates or increases the frequency, rate or extent of chromatin silencing.
|
2 | Q5UAK0 (/ISO) Q5UAK0 (/ISO) |
|
Positive regulation of I-kappaB kinase/NF-kappaB signaling GO:0043123
Any process that activates or increases the frequency, rate or extent of I-kappaB kinase/NF-kappaB signaling.
|
2 | Q8N108 (/HMP) Q8N108 (/HMP) |
There are 11 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Transcriptional repressor complex GO:0017053
A protein complex that possesses activity that prevents or downregulates transcription.
|
6 | Q5REE1 (/ISS) Q5REE1 (/ISS) Q5UAK0 (/ISS) Q5UAK0 (/ISS) Q5ZKT9 (/ISS) Q7T105 (/ISS) |
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
5 | Q7Z3K6 (/IDA) Q7Z3K6 (/IDA) Q8N108 (/IDA) Q8N108 (/IDA) Q8N344 (/IDA) |
|
Protein-containing complex GO:0032991
A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together.
|
5 | Q7Z3K6 (/IDA) Q7Z3K6 (/IDA) Q8N108 (/IDA) Q8N108 (/IDA) Q8N344 (/IDA) |
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
4 | Q3U3N0 (/ISO) Q3UHF3 (/ISO) Q5UAK0 (/ISO) Q5UAK0 (/ISO) |
|
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
|
4 | Q7Z3K6 (/IDA) Q7Z3K6 (/IDA) Q8N108 (/IDA) Q8N108 (/IDA) |
|
Protein-containing complex GO:0032991
A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together.
|
4 | Q3U3N0 (/ISO) Q3UHF3 (/ISO) Q5UAK0 (/ISO) Q5UAK0 (/ISO) |
|
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
|
3 | Q3UHF3 (/ISO) Q5UAK0 (/ISO) Q5UAK0 (/ISO) |
|
Transcriptional repressor complex GO:0017053
A protein complex that possesses activity that prevents or downregulates transcription.
|
2 | Q8N108 (/IDA) Q8N108 (/IDA) |
|
Transcriptional repressor complex GO:0017053
A protein complex that possesses activity that prevents or downregulates transcription.
|
2 | Q5UAK0 (/ISO) Q5UAK0 (/ISO) |
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
1 | Q8N344 (/IDA) |
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
1 | Q3U3N0 (/ISO) |
