The chemical reactions and pathways resulting in the formation of sphingolipids, any of a class of lipids containing the long-chain amine diol sphingosine or a closely related base (a sphingoid).

The chemical reactions and pathways resulting in the formation of sphingolipids, any of a class of lipids containing the long-chain amine diol sphingosine or a closely related base (a sphingoid).

The chemical reactions and pathways resulting in the formation of ceramides, any N-acylated sphingoid.

Any process that stops, prevents, or reduces the frequency, rate or extent of axon regeneration.

Any process that stops, prevents or reduces the frequency, rate or extent of Schwann cell migration.

Any process that stops, prevents or reduces the frequency, rate or extent of Schwann cell proliferation involved in axon regeneration.

The chemical reactions and pathways resulting in the formation of ceramides, any N-acylated sphingoid.

The chemical reactions and pathways resulting in the formation of ceramides, any N-acylated sphingoid.

The chemical reactions and pathways involving triglyceride, any triester of glycerol. The three fatty acid residues may all be the same or differ in any permutation. Triglycerides are important components of plant oils, animal fats and animal plasma lipoproteins.

The process in which a relatively unspecialized cell acquires specialized features of a keratinocyte.

The process in which a relatively unspecialized cell acquires specialized features of a keratinocyte.

A series of molecular signals from the endoplasmic reticulum to the nucleus generated as a consequence of decreased levels of one or more sterols (and in some yeast, changes in oxygen levels) and which proceeds through activation of a sterol response element binding transcription factor (SREBP) to result in up-regulation of target gene transcription.

Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of lipids.

Any process that stops, prevents, or reduces the frequency, rate or extent of axon regeneration.

Any process that stops, prevents, or reduces the frequency, rate or extent of axon regeneration.

Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of lipids.

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ceramide stimulus.

Any process that stops, prevents or reduces the frequency, rate or extent of Schwann cell migration.

Any process that stops, prevents or reduces the frequency, rate or extent of Schwann cell migration.

Any process that stops, prevents or reduces the frequency, rate or extent of Schwann cell proliferation involved in axon regeneration.

Any process that stops, prevents or reduces the frequency, rate or extent of Schwann cell proliferation involved in axon regeneration.

The lipid bilayer surrounding the endoplasmic reticulum.

A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.

The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).

A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

The inner, i.e. lumen-facing, lipid bilayer of the nuclear envelope.

The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.