The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:

"
Homeodomain-like
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 2: Myb family transcription factor

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 6 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
DNA-binding transcription factor activity GO:0003700
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons.
47 C0SVS4 (/ISS) F4I274 (/ISS) F4J3P7 (/ISS) F4JRB0 (/ISS) Q0WVU3 (/ISS) Q700D9 (/ISS) Q700D9 (/ISS) Q7X887 (/ISS) Q8GUN5 (/ISS) Q8GUN5 (/ISS)
(37 more)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
16 C0SVS4 (/IPI) F4JRB0 (/IPI) Q5VRW2 (/IPI) Q7X887 (/IPI) Q8GYE4 (/IPI) Q8GYE4 (/IPI) Q8LAJ7 (/IPI) Q8LAJ7 (/IPI) Q8VZS3 (/IPI) Q93WJ9 (/IPI)
(6 more)
Sequence-specific DNA binding GO:0043565
Interacting selectively and non-covalently with DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding.
9 Q6Z869 (/IDA) Q6Z869 (/IDA) Q6Z869 (/IDA) Q6Z869 (/IDA) Q6Z869 (/IDA) Q8LAJ7 (/IDA) Q8LAJ7 (/IDA) Q94A57 (/IDA) Q94A57 (/IDA)
DNA-binding transcription factor activity GO:0003700
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons.
5 Q8VZS3 (/IDA) Q9FPE8 (/IDA) Q9FX67 (/IDA) Q9FX67 (/IDA) Q9LS00 (/IDA)
Sequence-specific DNA binding GO:0043565
Interacting selectively and non-covalently with DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding.
4 Q8LAJ7 (/IPI) Q8LAJ7 (/IPI) Q94A57 (/IPI) Q94A57 (/IPI)
Transcription regulatory region DNA binding GO:0044212
Interacting selectively and non-covalently with a DNA region that regulates the transcription of a region of DNA, which may be a gene, cistron, or operon. Binding may occur as a sequence specific interaction or as an interaction observed only once a factor has been recruited to the DNA by other factors.
2 F4JRB0 (/IDA) Q9FJV5 (/IDA)

There are 40 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Regulation of transcription, DNA-templated GO:0006355
Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.
37 C0SVS4 (/TAS) F4I274 (/TAS) F4J3P7 (/TAS) F4JRB0 (/TAS) Q0WVU3 (/TAS) Q700D9 (/TAS) Q700D9 (/TAS) Q7X887 (/TAS) Q8GXC2 (/TAS) Q8GYE4 (/TAS)
(27 more)
Cellular response to phosphate starvation GO:0016036
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of phosphate.
7 Q94A57 (/IMP) Q94A57 (/IMP) Q94CL7 (/IMP) Q94CL7 (/IMP) Q9FX67 (/IMP) Q9FX67 (/IMP) Q9LS00 (/IMP)
Negative regulation of transcription, DNA-templated GO:0045892
Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription.
5 Q6Z869 (/IDA) Q6Z869 (/IDA) Q6Z869 (/IDA) Q6Z869 (/IDA) Q6Z869 (/IDA)
Abaxial cell fate specification GO:0010158
The process in which a cell becomes capable of differentiating autonomously into an abaxial cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed.
4 Q0J235 (/IMP) Q0J235 (/IMP) Q93WJ9 (/IMP) Q93WJ9 (/IMP)
Positive regulation of gene expression GO:0010628
Any process that increases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.
4 Q8LAJ7 (/IDA) Q8LAJ7 (/IDA) Q94A57 (/IDA) Q94A57 (/IDA)
Polarity specification of adaxial/abaxial axis GO:0009944
The process resulting in the establishment of polarity along the adaxial/abaxial axis. Adaxial refers to being situated toward an axis of an anatomical structure. Abaxial refers to being situated away from an axis of an anatomical structure.
3 Q93WJ9 (/IGI) Q93WJ9 (/IGI) Q9C616 (/IGI)
Carpel development GO:0048440
The process whose specific outcome is the progression of the carpel over time, from its formation to the mature structure. A carpel is an organ (generally believed to be a modified foliar unit) at the centre of a flower, bearing one or more ovules and having its margins fused together or with other carpels to enclose the ovule in an ovary, and consisting also of a stigma and usually a style.
3 Q93WJ9 (/IGI) Q93WJ9 (/IGI) Q9C616 (/IGI)
Plant ovule development GO:0048481
The process whose specific outcome is the progression of the ovule over time, from its formation to the mature structure. The ovule is the structure in seed plants enclosing the female gametophyte, and is composed of the nucellus, one or two integuments, and the funiculus; it develops into the seed.
3 Q93WJ9 (/IGI) Q93WJ9 (/IGI) Q9C616 (/IGI)
Circadian rhythm GO:0007623
Any biological process in an organism that recurs with a regularity of approximately 24 hours.
2 Q94CL7 (/IEP) Q94CL7 (/IEP)
Double fertilization forming a zygote and endosperm GO:0009567
Fertilization where one of the two sperm nuclei from the pollen tube fuses with the egg nucleus to form a 2n zygote, and the other fuses with the two polar nuclei to form the 3n primary endosperm nucleus and then develops into the endosperm. The ploidy level of the 2n zygote and 3n primary endosperm nucleus is determined by the ploidy level of the parents involved. An example of this component is found in Arabidopsis thaliana.
2 Q8LAJ7 (/IMP) Q8LAJ7 (/IMP)
Negative regulation of abscisic acid-activated signaling pathway GO:0009788
Any process that stops, prevents, or reduces the frequency, rate or extent of abscisic acid (ABA) signaling.
2 Q9FX67 (/IMP) Q9FX67 (/IMP)
Adaxial/abaxial axis specification GO:0009943
The establishment, maintenance and elaboration of the adaxial / abaxial axis. Adaxial refers to being situated toward an axis of an anatomical structure. Abaxial refers to being situated away from an axis of an anatomical structure.
2 Q93WJ9 (/IMP) Q93WJ9 (/IMP)
Radial pattern formation GO:0009956
The regionalization process that results in defined areas around a point in which specific types of cell differentiation will occur.
2 Q93WJ9 (/IMP) Q93WJ9 (/IMP)
Xylem and phloem pattern formation GO:0010051
The regionalization process that gives rise to the patterning of the conducting tissues. An example of this process is found in Arabidopsis thaliana.
2 Q93WJ9 (/IMP) Q93WJ9 (/IMP)
Inflorescence development GO:0010229
The process whose specific outcome is the progression of an inflorescence over time, from its formation to the mature structure.
2 Q0J235 (/IMP) Q0J235 (/IMP)
Regulation of response to nutrient levels GO:0032107
Any process that modulates the frequency, rate or extent of a response to nutrient levels.
2 Q9FX67 (/IGI) Q9FX67 (/IGI)
Sulfate ion homeostasis GO:0055063
Any process involved in the maintenance of an internal steady state of sulfate ions within an organism or cell.
2 Q94CL7 (/IMP) Q94CL7 (/IMP)
Cellular response to high light intensity GO:0071486
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a high light intensity stimulus.
2 Q94CL7 (/IMP) Q94CL7 (/IMP)
Primary root development GO:0080022
The process whose specific outcome is the progression of the primary root over time, from its formation to the mature structure. The primary root develops directly from the embryonic radicle.
2 Q9FX67 (/IMP) Q9FX67 (/IMP)
Cellular response to nitrogen compound GO:1901699
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitrogen compound stimulus.
2 Q9FX67 (/IEP) Q9FX67 (/IEP)
Plant organ morphogenesis GO:1905392
The developmental process by which a plant organ is generated and organized.
2 Q93WJ9 (/IMP) Q93WJ9 (/IMP)
Regulation of transcription, DNA-templated GO:0006355
Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.
1 Q9FJV5 (/IMP)
Response to temperature stimulus GO:0009266
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a temperature stimulus.
1 Q9ZQ85 (/IEP)
Pollen development GO:0009555
The process whose specific outcome is the progression of the pollen grain over time, from its formation to the mature structure. The process begins with the meiosis of the microsporocyte to form four haploid microspores. The nucleus of each microspore then divides by mitosis to form a two-celled organism, the pollen grain, that contains a tube cell as well as a smaller generative cell. The pollen grain is surrounded by an elaborate cell wall. In some species, the generative cell immediately divides again to give a pair of sperm cells. In most flowering plants, however this division takes place later, in the tube that develops when a pollen grain germinates.
1 Q8GXC2 (/IMP)
Response to abscisic acid GO:0009737
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an abscisic acid stimulus.
1 Q8VZS3 (/IMP)
Gibberellic acid mediated signaling pathway GO:0009740
A series of molecular signals mediated by the detection of gibberellic acid.
1 Q9ZQ85 (/IEP)
Phloem development GO:0010088
The formation of the principal food-conducting tissue of a vascular plant.
1 Q9SAK5 (/IMP)
Xylem development GO:0010089
The formation of the principal water-conducting tissue of a vascular plant.
1 Q9SAK5 (/IMP)
Histone H3-K36 methylation GO:0010452
The modification of histone H3 by addition of one or more methyl groups to lysine at position 36 of the histone.
1 Q9ZQ85 (/IPI)
Negative regulation of gene expression GO:0010629
Any process that decreases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.
1 F4JRB0 (/IDA)
Positive regulation of transcription, DNA-templated GO:0045893
Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.
1 Q9SAK5 (/IEP)
Floral organ formation GO:0048449
The process that gives rise to floral organs. This process pertains to the initial formation of a structure from unspecified parts.
1 F4JRB0 (/IMP)
Plant ovule development GO:0048481
The process whose specific outcome is the progression of the ovule over time, from its formation to the mature structure. The ovule is the structure in seed plants enclosing the female gametophyte, and is composed of the nucellus, one or two integuments, and the funiculus; it develops into the seed.
1 Q9FJV5 (/IMP)
Negative regulation of long-day photoperiodism, flowering GO:0048579
Any process that stops, prevents or reduces long-day photoperiodism, where the response associated with the photoperiodism is flowering. Flowering is defined by the switch from the vegetative to the reproductive phase.
1 Q9ZQ85 (/IMP)
Phosphate ion homeostasis GO:0055062
Any process involved in the maintenance of an internal steady state of phosphate ions within an organism or cell.
1 Q8VZS3 (/IMP)
Integument development GO:0080060
The process whose specific outcome is the progression of the integument over time, from its formation to the mature structure. Integument is one of the layers of tissue that usually covers the ovule, enveloping the nucellus and forming the micropyle at the apex.
1 Q9FJV5 (/IGI)
Integument development GO:0080060
The process whose specific outcome is the progression of the integument over time, from its formation to the mature structure. Integument is one of the layers of tissue that usually covers the ovule, enveloping the nucellus and forming the micropyle at the apex.
1 Q9FJV5 (/IMP)
Response to nitrate starvation GO:0090548
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a starvation stimulus, deprivation of nitrate.
1 Q9LS00 (/IMP)
Specification of plant organ identity GO:0090701
The regionalization process in which the identity of a plant organ primordium is specified. Identity is considered to be the aggregate of characteristics by which a structure is recognized.
1 F4JRB0 (/IMP)
Negative regulation of nucleic acid-templated transcription GO:1903507
Any process that stops, prevents or reduces the frequency, rate or extent of nucleic acid-templated transcription.
1 Q9ZQ85 (/IPI)

There are 4 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
21 F4JRB0 (/IDA) Q0J235 (/IDA) Q0J235 (/IDA) Q6Z869 (/IDA) Q6Z869 (/IDA) Q6Z869 (/IDA) Q6Z869 (/IDA) Q6Z869 (/IDA) Q8GXC2 (/IDA) Q8LAJ7 (/IDA)
(11 more)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
2 Q93WJ9 (/ISS) Q93WJ9 (/ISS)
Cell wall GO:0005618
The rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal, most prokaryotic cells and some protozoan parasites, maintaining their shape and protecting them from osmotic lysis. In plants it is made of cellulose and, often, lignin; in fungi it is composed largely of polysaccharides; in bacteria it is composed of peptidoglycan; in protozoan parasites such as Giardia species, it's made of carbohydrates and proteins.
1 Q9FJV5 (/IDA)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
1 F4JRB0 (/IDA)
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