The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:
"Homeodomain-like
".
FunFam 16: Transcriptional activator Myb isoform A
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 27 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
12 |
A0A2R8Q8E3 (/IPI)
A0A2R8RYE8 (/IPI)
F1QP24 (/IPI)
F1QP25 (/IPI)
P01103 (/IPI)
P06876 (/IPI)
P10242 (/IPI)
P10242 (/IPI)
Q6PBA4 (/IPI)
Q8H1P9 (/IPI)
(2 more) |
|
DNA-binding transcription factor activity, RNA polymerase II-specific GO:0000981
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.
|
9 | A0A2R8Q8E3 (/IDA) A0A2R8RYE8 (/IDA) F1QP24 (/IDA) F1QP25 (/IDA) P22035 (/IDA) P22035 (/IDA) P51960 (/IDA) Q6PBA4 (/IDA) Q9PTJ4 (/IDA) |
|
DNA-binding transcription factor activity GO:0003700
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons.
|
7 | F4JV48 (/ISS) Q6R032 (/ISS) Q8H1P9 (/ISS) Q94FL9 (/ISS) Q9LV31 (/ISS) Q9LV31 (/ISS) Q9SPN3 (/ISS) |
|
RNA polymerase II proximal promoter sequence-specific DNA binding GO:0000978
Interacting selectively and non-covalently with a specific upstream regulatory DNA sequence (transcription factor recognition sequence or binding site) located in the proximal promoter of a gene transcribed by RNA polymerase II. The proximal promoter is in cis with and relatively close to the core promoter.
|
6 | P06876 (/IDA) P10242 (/IDA) P10242 (/IDA) P10243 (/IDA) P22035 (/IDA) P22035 (/IDA) |
|
DNA-binding transcription factor activity, RNA polymerase II-specific GO:0000981
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.
|
6 | A0A2R8Q8E3 (/IGI) A0A2R8RYE8 (/IGI) F1QP24 (/IGI) F1QP25 (/IGI) Q6PBA4 (/IGI) Q9PTJ4 (/IGI) |
|
DNA-binding transcription factor activity, RNA polymerase II-specific GO:0000981
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.
|
5 | P10242 (/ISA) P10242 (/ISA) P10243 (/ISA) Q5SXM2 (/ISA) Q5SXM2 (/ISA) |
|
DNA-binding transcription factor activity, RNA polymerase II-specific GO:0000981
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.
|
5 | P10242 (/ISM) P10242 (/ISM) P10243 (/ISM) Q5SXM2 (/ISM) Q5SXM2 (/ISM) |
|
DNA-binding transcription factor activity, RNA polymerase II-specific GO:0000981
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.
|
5 | P10242 (/NAS) P10242 (/NAS) P10243 (/NAS) Q5SXM2 (/NAS) Q5SXM2 (/NAS) |
|
DNA binding GO:0003677
Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
|
4 | P06876 (/IDA) P34127 (/IDA) Q5SXM2 (/IDA) Q5SXM2 (/IDA) |
|
Sequence-specific DNA binding GO:0043565
Interacting selectively and non-covalently with DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding.
|
3 | Q0JHU7 (/IDA) Q94FL9 (/IDA) Q9S7G7 (/IDA) |
|
Sequence-specific DNA binding GO:0043565
Interacting selectively and non-covalently with DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding.
|
3 | Q6R032 (/ISS) Q8H1P9 (/ISS) Q9SPN3 (/ISS) |
|
RNA polymerase II proximal promoter sequence-specific DNA binding GO:0000978
Interacting selectively and non-covalently with a specific upstream regulatory DNA sequence (transcription factor recognition sequence or binding site) located in the proximal promoter of a gene transcribed by RNA polymerase II. The proximal promoter is in cis with and relatively close to the core promoter.
|
2 | P06876 (/ISO) P51960 (/ISO) |
|
DNA-binding transcription factor activity, RNA polymerase II-specific GO:0000981
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.
|
2 | P22035 (/IMP) P22035 (/IMP) |
|
RNA polymerase II transcription regulator recruiting activity GO:0001135
The function of binding to an RNA polymerase II (RNAP II) transcription regulator and recruiting it to the general transcription machinery complex in order to modulate transcription initiation.
|
2 | P22035 (/IDA) P22035 (/IDA) |
|
RNA polymerase II transcription regulator recruiting activity GO:0001135
The function of binding to an RNA polymerase II (RNAP II) transcription regulator and recruiting it to the general transcription machinery complex in order to modulate transcription initiation.
|
2 | P22035 (/IMP) P22035 (/IMP) |
|
DNA-binding transcription activator activity, RNA polymerase II-specific GO:0001228
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to activate or increase transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.
|
2 | P10242 (/IC) P10242 (/IC) |
|
DNA-binding transcription activator activity, RNA polymerase II-specific GO:0001228
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to activate or increase transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.
|
2 | P06876 (/IDA) P10243 (/IDA) |
|
DNA binding GO:0003677
Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
|
2 | Q5SXM2 (/TAS) Q5SXM2 (/TAS) |
|
DNA-binding transcription factor activity GO:0003700
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons.
|
2 | Q5SXM2 (/TAS) Q5SXM2 (/TAS) |
|
Transcription coactivator activity GO:0003713
A protein or a member of a complex that interacts specifically and non-covalently with a DNA-bound DNA-binding transcription factor to activate the transcription of specific genes. Coactivators often act by altering chromatin structure and modifications. For example, one class of transcription coregulators modifies chromatin structure through covalent modification of histones. A second ATP-dependent class modifies the conformation of chromatin. Another type of coregulator activity is the bridging of a DNA-binding transcription factor to the basal transcription machinery. The Mediator complex, which bridges transcription factors and RNA polymerase, is also a transcription coactivator.
|
2 | F4JV48 (/IDA) Q94FL9 (/IDA) |
|
DNA-binding transcription factor activity, RNA polymerase II-specific GO:0000981
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.
|
1 | Q05935 (/ISS) |
|
DNA-binding transcription activator activity, RNA polymerase II-specific GO:0001228
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to activate or increase transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.
|
1 | P51960 (/ISO) |
|
DNA binding GO:0003677
Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
|
1 | Q8BP86 (/ISO) |
|
DNA binding GO:0003677
Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
|
1 | Q8BP86 (/ISS) |
|
DNA-binding transcription factor activity GO:0003700
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons.
|
1 | P06876 (/IDA) |
|
DNA-binding transcription factor activity GO:0003700
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons.
|
1 | P06876 (/IMP) |
|
WD40-repeat domain binding GO:0071987
Interacting selectively and non-covalently with a WD40 repeat domain of a protein. The WD40 repeat is a short structural motif of approximately 40 amino acids, often terminating in a tryptophan-aspartic acid (W-D) dipeptide. Several of these repeats are combined to form a type of protein domain called the WD domain.
|
1 | P06876 (/IDA) |
There are 99 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Positive regulation of transcription by RNA polymerase II GO:0045944
Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
|
7 | P06876 (/IDA) P10242 (/IDA) P10242 (/IDA) P10243 (/IDA) P22035 (/IDA) P22035 (/IDA) P51960 (/IDA) |
|
Eye development GO:0001654
The process whose specific outcome is the progression of the eye over time, from its formation to the mature structure. The eye is the organ of sight.
|
6 | A0A2R8Q8E3 (/IMP) A0A2R8RYE8 (/IMP) F1QP24 (/IMP) F1QP25 (/IMP) Q6PBA4 (/IMP) Q9PTJ4 (/IMP) |
|
Hematopoietic stem cell migration GO:0035701
The orderly movement of a hematopoietic stem cell from one site to another. A hematopoietic stem cell is a cell from which all cells of the lymphoid and myeloid lineages develop, including blood cells and cells of the immune system.
|
6 | A0A2R8Q8E3 (/IGI) A0A2R8RYE8 (/IGI) F1QP24 (/IGI) F1QP25 (/IGI) Q6PBA4 (/IGI) Q9PTJ4 (/IGI) |
|
Chordate embryonic development GO:0043009
The process whose specific outcome is the progression of the embryo over time, from zygote formation through a stage including a notochord and neural tube until birth or egg hatching.
|
6 | A0A2R8Q8E3 (/IGI) A0A2R8RYE8 (/IGI) F1QP24 (/IGI) F1QP25 (/IGI) Q6PBA4 (/IGI) Q9PTJ4 (/IGI) |
|
Chordate embryonic development GO:0043009
The process whose specific outcome is the progression of the embryo over time, from zygote formation through a stage including a notochord and neural tube until birth or egg hatching.
|
6 | A0A2R8Q8E3 (/IMP) A0A2R8RYE8 (/IMP) F1QP24 (/IMP) F1QP25 (/IMP) Q6PBA4 (/IMP) Q9PTJ4 (/IMP) |
|
Regulation of neutrophil differentiation GO:0045658
Any process that modulates the frequency, rate or extent of neutrophil differentiation.
|
6 | A0A2R8Q8E3 (/IGI) A0A2R8RYE8 (/IGI) F1QP24 (/IGI) F1QP25 (/IGI) Q6PBA4 (/IGI) Q9PTJ4 (/IGI) |
|
Regulation of neutrophil differentiation GO:0045658
Any process that modulates the frequency, rate or extent of neutrophil differentiation.
|
6 | A0A2R8Q8E3 (/IMP) A0A2R8RYE8 (/IMP) F1QP24 (/IMP) F1QP25 (/IMP) Q6PBA4 (/IMP) Q9PTJ4 (/IMP) |
|
Definitive hemopoiesis GO:0060216
A second wave of blood cell production that, in vertebrates, generates long-term hemopoietic stem cells that continously provide erythroid, myeloid and lymphoid lineages throughout adulthood.
|
6 | A0A2R8Q8E3 (/IMP) A0A2R8RYE8 (/IMP) F1QP24 (/IMP) F1QP25 (/IMP) Q6PBA4 (/IMP) Q9PTJ4 (/IMP) |
|
Cilium assembly GO:0060271
The assembly of a cilium, a specialized eukaryotic organelle that consists of a filiform extrusion of the cell surface. Each cilium is bounded by an extrusion of the cytoplasmic membrane, and contains a regular longitudinal array of microtubules, anchored basally in a centriole.
|
6 | A0A2R8Q8E3 (/IGI) A0A2R8RYE8 (/IGI) F1QP24 (/IGI) F1QP25 (/IGI) Q6PBA4 (/IGI) Q9PTJ4 (/IGI) |
|
Cilium assembly GO:0060271
The assembly of a cilium, a specialized eukaryotic organelle that consists of a filiform extrusion of the cell surface. Each cilium is bounded by an extrusion of the cytoplasmic membrane, and contains a regular longitudinal array of microtubules, anchored basally in a centriole.
|
6 | A0A2R8Q8E3 (/IMP) A0A2R8RYE8 (/IMP) F1QP24 (/IMP) F1QP25 (/IMP) Q6PBA4 (/IMP) Q9PTJ4 (/IMP) |
|
Negative regulation of transcription, DNA-templated GO:0045892
Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription.
|
5 | P10242 (/IMP) P10242 (/IMP) Q6R032 (/IMP) Q8H1P9 (/IMP) Q9S7G7 (/IMP) |
|
Positive regulation of transcription by RNA polymerase II GO:0045944
Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
|
5 | P10242 (/IMP) P10242 (/IMP) P22035 (/IMP) P22035 (/IMP) P51960 (/IMP) |
|
Positive regulation of transcription, DNA-templated GO:0045893
Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.
|
4 | P10242 (/IMP) P10242 (/IMP) Q94FL9 (/IMP) Q9S7G7 (/IMP) |
|
Negative regulation of transcription by RNA polymerase II GO:0000122
Any process that stops, prevents, or reduces the frequency, rate or extent of transcription mediated by RNA polymerase II.
|
3 | P10242 (/IMP) P10242 (/IMP) P34127 (/IMP) |
|
Regulation of transcription, DNA-templated GO:0006355
Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.
|
3 | F4JV48 (/IDA) P06876 (/IDA) Q94FL9 (/IDA) |
|
Regulation of transcription, DNA-templated GO:0006355
Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.
|
3 | Q94FL9 (/TAS) Q9LV31 (/TAS) Q9LV31 (/TAS) |
|
Negative regulation of cell population proliferation GO:0008285
Any process that stops, prevents or reduces the rate or extent of cell proliferation.
|
3 | Q6R032 (/IMP) Q8H1P9 (/IMP) Q9S7G7 (/IMP) |
|
Response to salicylic acid GO:0009751
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a salicylic acid stimulus.
|
3 | Q6R032 (/IEP) Q8H1P9 (/IEP) Q94FL9 (/IEP) |
|
Positive regulation of transcription, DNA-templated GO:0045893
Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.
|
3 | P10242 (/NAS) P10242 (/NAS) P10243 (/NAS) |
|
Positive regulation of transcription by RNA polymerase II GO:0045944
Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
|
3 | P06876 (/IGI) P22035 (/IGI) P22035 (/IGI) |
|
Response to hypoxia GO:0001666
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating lowered oxygen tension. Hypoxia, defined as a decline in O2 levels below normoxic levels of 20.8 - 20.95%, results in metabolic adaptation at both the cellular and organismal level.
|
2 | A0A0G2JV86 (/IEP) A0A0G2K2A4 (/IEP) |
|
Chromatin remodeling GO:0006338
Dynamic structural changes to eukaryotic chromatin occurring throughout the cell division cycle. These changes range from the local changes necessary for transcriptional regulation to global changes necessary for chromosome segregation.
|
2 | P10242 (/IMP) P10242 (/IMP) |
|
Regulation of transcription, DNA-templated GO:0006355
Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.
|
2 | P10242 (/NAS) P10242 (/NAS) |
|
Transcription by RNA polymerase II GO:0006366
The synthesis of RNA from a DNA template by RNA polymerase II (RNAP II), originating at an RNA polymerase II promoter. Includes transcription of messenger RNA (mRNA) and certain small nuclear RNAs (snRNAs).
|
2 | Q5SXM2 (/TAS) Q5SXM2 (/TAS) |
|
Transcription by RNA polymerase III GO:0006383
The synthesis of RNA from a DNA template by RNA polymerase III, originating at an RNAP III promoter.
|
2 | Q5SXM2 (/TAS) Q5SXM2 (/TAS) |
|
Male meiosis I GO:0007141
A cell cycle process comprising the steps by which a cell progresses through male meiosis I, the first meiotic division in the male germline.
|
2 | P10243 (/ISS) Q05935 (/ISS) |
|
Spermatogenesis GO:0007283
The process of formation of spermatozoa, including spermatocytogenesis and spermiogenesis.
|
2 | P10243 (/ISS) Q05935 (/ISS) |
|
SnRNA transcription GO:0009301
The synthesis of small nuclear RNA (snRNA) from a DNA template.
|
2 | Q5SXM2 (/TAS) Q5SXM2 (/TAS) |
|
Response to ethylene GO:0009723
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ethylene (ethene) stimulus.
|
2 | Q6R032 (/IEP) Q8H1P9 (/IEP) |
|
Negative regulation of transposition GO:0010529
Any process that decreases the frequency, rate or extent of transposition. Transposition results in the movement of discrete segments of DNA between nonhomologous sites.
|
2 | P10243 (/ISS) Q05935 (/ISS) |
|
Regulation of cytokinesis GO:0032465
Any process that modulates the frequency, rate or extent of the division of the cytoplasm of a cell and its separation into two daughter cells.
|
2 | Q94FL9 (/IGI) Q9S7G7 (/IGI) |
|
Positive regulation of collagen biosynthetic process GO:0032967
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals.
|
2 | A0A0G2JV86 (/IMP) A0A0G2K2A4 (/IMP) |
|
SnRNA transcription by RNA polymerase II GO:0042795
The synthesis of small nuclear RNA (snRNA) from a DNA template by RNA Polymerase II (Pol II), originating at a Pol II promoter.
|
2 | Q5SXM2 (/IDA) Q5SXM2 (/IDA) |
|
SnRNA transcription by RNA polymerase II GO:0042795
The synthesis of small nuclear RNA (snRNA) from a DNA template by RNA Polymerase II (Pol II), originating at a Pol II promoter.
|
2 | Q5SXM2 (/TAS) Q5SXM2 (/TAS) |
|
SnRNA transcription by RNA polymerase III GO:0042796
The synthesis of small nuclear RNA (snRNA) from a DNA template by RNA Polymerase III (Pol III), originating at a Pol III promoter.
|
2 | Q5SXM2 (/IDA) Q5SXM2 (/IDA) |
|
Positive regulation of neuron apoptotic process GO:0043525
Any process that activates or increases the frequency, rate or extent of cell death of neurons by apoptotic process.
|
2 | A0A0G2JV86 (/IMP) A0A0G2K2A4 (/IMP) |
|
Positive regulation of T-helper cell differentiation GO:0045624
Any process that activates or increases the frequency, rate or extent of T-helper cell differentiation.
|
2 | P10242 (/IMP) P10242 (/IMP) |
|
Positive regulation of transcription by RNA polymerase II GO:0045944
Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
|
2 | P06876 (/ISO) P51960 (/ISO) |
|
Positive regulation of smooth muscle cell proliferation GO:0048661
Any process that activates or increases the rate or extent of smooth muscle cell proliferation.
|
2 | A0A0G2JV86 (/IMP) A0A0G2K2A4 (/IMP) |
|
Positive regulation of histone H3-K4 methylation GO:0051571
Any process that activates or increases the frequency, rate or extent of the covalent addition of a methyl group to the lysine at position 4 of histone H3.
|
2 | P10242 (/IMP) P10242 (/IMP) |
|
Positive regulation of histone H3-K9 methylation GO:0051574
Any process that activates or increases the frequency, rate or extent of the covalent addition of a methyl group to the lysine at position 9 of histone H3.
|
2 | P10242 (/IMP) P10242 (/IMP) |
|
Positive regulation of glial cell proliferation GO:0060252
Any process that activates or increases the rate or extent of glial cell proliferation.
|
2 | A0A0G2JV86 (/IMP) A0A0G2K2A4 (/IMP) |
|
Cellular response to hydrogen peroxide GO:0070301
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydrogen peroxide (H2O2) stimulus.
|
2 | A0A0G2JV86 (/IEP) A0A0G2K2A4 (/IEP) |
|
Cellular response to retinoic acid GO:0071300
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a retinoic acid stimulus.
|
2 | A0A0G2JV86 (/IEP) A0A0G2K2A4 (/IEP) |
|
Positive regulation of transforming growth factor beta production GO:0071636
Any process that activates or increases the frequency, rate, or extent of production of transforming growth factor-beta.
|
2 | A0A0G2JV86 (/IMP) A0A0G2K2A4 (/IMP) |
|
Negative regulation of cellular response to caffeine GO:1901181
Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to caffeine.
|
2 | Q94FL9 (/IMP) Q9S7G7 (/IMP) |
|
Positive regulation of neuron death GO:1901216
Any process that activates or increases the frequency, rate or extent of neuron death.
|
2 | A0A0G2JV86 (/IMP) A0A0G2K2A4 (/IMP) |
|
Regulation of hematopoietic stem cell differentiation GO:1902036
Any process that modulates the frequency, rate or extent of hematopoietic stem cell differentiation.
|
2 | P10242 (/TAS) P10242 (/TAS) |
|
Positive regulation of hepatic stellate cell proliferation GO:1904899
Any process that activates or increases the frequency, rate or extent of hepatic stellate cell proliferation.
|
2 | A0A0G2JV86 (/IMP) A0A0G2K2A4 (/IMP) |
|
PiRNA biosynthetic process GO:1990511
The chemical reactions and pathways resulting in the formation of piRNAs, Piwi-associated RNAs, a class of 24- to 30-nucleotide RNA derived from repeat or complex DNA sequence elements and processed by a Dicer-independent mechanism.
|
2 | P10243 (/ISS) Q05935 (/ISS) |
|
Positive regulation of hepatic stellate cell activation GO:2000491
Any process that activates or increases the frequency, rate or extent of hepatic stellate cell activation.
|
2 | A0A0G2JV86 (/IMP) A0A0G2K2A4 (/IMP) |
|
Positive regulation of testosterone secretion GO:2000845
Any process that activates or increases the frequency, rate or extent of testosterone secretion.
|
2 | A0A0G2JV86 (/IMP) A0A0G2K2A4 (/IMP) |
|
G1/S transition of mitotic cell cycle GO:0000082
The mitotic cell cycle transition by which a cell in G1 commits to S phase. The process begins with the build up of G1 cyclin-dependent kinase (G1 CDK), resulting in the activation of transcription of G1 cyclins. The process ends with the positive feedback of the G1 cyclins on the G1 CDK which commits the cell to S phase, in which DNA replication is initiated.
|
1 | P06876 (/IMP) |
|
Negative regulation of transcription by RNA polymerase II GO:0000122
Any process that stops, prevents, or reduces the frequency, rate or extent of transcription mediated by RNA polymerase II.
|
1 | P06876 (/ISO) |
|
In utero embryonic development GO:0001701
The process whose specific outcome is the progression of the embryo in the uterus over time, from formation of the zygote in the oviduct, to birth. An example of this process is found in Mus musculus.
|
1 | P06876 (/IMP) |
|
Chromatin remodeling GO:0006338
Dynamic structural changes to eukaryotic chromatin occurring throughout the cell division cycle. These changes range from the local changes necessary for transcriptional regulation to global changes necessary for chromosome segregation.
|
1 | P06876 (/ISO) |
|
Regulation of transcription, DNA-templated GO:0006355
Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.
|
1 | P06876 (/IMP) |
|
Calcium ion transport GO:0006816
The directed movement of calcium (Ca) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
|
1 | P06876 (/IMP) |
|
Cellular response to DNA damage stimulus GO:0006974
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to its DNA from environmental insults or errors during metabolism.
|
1 | Q8H1P9 (/IMP) |
|
Male meiosis I GO:0007141
A cell cycle process comprising the steps by which a cell progresses through male meiosis I, the first meiotic division in the male germline.
|
1 | P51960 (/IMP) |
|
Spermatogenesis GO:0007283
The process of formation of spermatozoa, including spermatocytogenesis and spermiogenesis.
|
1 | P51960 (/IMP) |
|
Purine nucleobase biosynthetic process GO:0009113
The chemical reactions and pathways resulting in the formation of purine nucleobases, one of the two classes of nitrogen-containing ring compounds found in DNA and RNA, which include adenine and guanine.
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1 | Q5A683 (/ISS) |
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Response to cold GO:0009409
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cold stimulus, a temperature stimulus below the optimal temperature for that organism.
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1 | Q0JHU7 (/IMP) |
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Response to fungus GO:0009620
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a fungus.
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1 | Q94FL9 (/IEP) |
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Response to parasitic fungus GO:0009623
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a parasitic fungus, a fungus which spends all or part of its life in or on another organism from which it obtains nourishment and/or protection.
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1 | Q94FL9 (/IMP) |
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Response to auxin GO:0009733
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an auxin stimulus.
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1 | Q8H1P9 (/IEP) |
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Response to jasmonic acid GO:0009753
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a jasmonic acid stimulus.
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1 | Q8H1P9 (/IEP) |
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Regulation of gene expression GO:0010468
Any process that modulates the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.
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1 | P06876 (/IMP) |
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Regulation of gene expression GO:0010468
Any process that modulates the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.
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1 | P01103 (/TAS) |
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Negative regulation of transposition GO:0010529
Any process that decreases the frequency, rate or extent of transposition. Transposition results in the movement of discrete segments of DNA between nonhomologous sites.
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1 | P51960 (/IMP) |
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Stem cell division GO:0017145
The self-renewing division of a stem cell. A stem cell is an undifferentiated cell, in the embryo or adult, that can undergo unlimited division and give rise to one or several different cell types.
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1 | P06876 (/IMP) |
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Myeloid cell differentiation GO:0030099
The process in which a relatively unspecialized myeloid precursor cell acquires the specialized features of any cell of the myeloid leukocyte, megakaryocyte, thrombocyte, or erythrocyte lineages.
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1 | P06876 (/IMP) |
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B cell differentiation GO:0030183
The process in which a precursor cell type acquires the specialized features of a B cell. A B cell is a lymphocyte of B lineage with the phenotype CD19-positive and capable of B cell mediated immunity.
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1 | P06876 (/IMP) |
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Filamentous growth GO:0030447
The process in which a multicellular organism, a unicellular organism or a group of unicellular organisms grow in a threadlike, filamentous shape.
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1 | Q5A683 (/IMP) |
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Regulation of cytokinesis GO:0032465
Any process that modulates the frequency, rate or extent of the division of the cytoplasm of a cell and its separation into two daughter cells.
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1 | Q94FL9 (/IMP) |
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Regulation of DNA endoreduplication GO:0032875
Any process that modulates the frequency, rate or extent of DNA endoreduplication.
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1 | Q94FL9 (/IMP) |
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Regulation of circadian rhythm GO:0042752
Any process that modulates the frequency, rate or extent of a circadian rhythm. A circadian rhythm is a biological process in an organism that recurs with a regularity of approximately 24 hours.
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1 | Q9SPN3 (/IMP) |
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SnRNA transcription by RNA polymerase II GO:0042795
The synthesis of small nuclear RNA (snRNA) from a DNA template by RNA Polymerase II (Pol II), originating at a Pol II promoter.
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1 | Q8BP86 (/ISO) |
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SnRNA transcription by RNA polymerase II GO:0042795
The synthesis of small nuclear RNA (snRNA) from a DNA template by RNA Polymerase II (Pol II), originating at a Pol II promoter.
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1 | Q8BP86 (/ISS) |
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SnRNA transcription by RNA polymerase III GO:0042796
The synthesis of small nuclear RNA (snRNA) from a DNA template by RNA Polymerase III (Pol III), originating at a Pol III promoter.
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1 | Q8BP86 (/ISO) |
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SnRNA transcription by RNA polymerase III GO:0042796
The synthesis of small nuclear RNA (snRNA) from a DNA template by RNA Polymerase III (Pol III), originating at a Pol III promoter.
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1 | Q8BP86 (/ISS) |
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Positive regulation of T-helper cell differentiation GO:0045624
Any process that activates or increases the frequency, rate or extent of T-helper cell differentiation.
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1 | P06876 (/ISO) |
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Negative regulation of transcription, DNA-templated GO:0045892
Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription.
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1 | P06876 (/ISO) |
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Positive regulation of transcription, DNA-templated GO:0045893
Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.
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1 | Q0JHU7 (/IDA) |
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Positive regulation of transcription, DNA-templated GO:0045893
Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.
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1 | P06876 (/ISO) |
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Positive regulation of transcription by RNA polymerase II GO:0045944
Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
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1 | Q05935 (/ISS) |
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Adenine biosynthetic process GO:0046084
The chemical reactions and pathways resulting in the formation of adenine, 6-aminopurine, one of the five main bases found in nucleic acids and a component of numerous important derivatives of its corresponding ribonucleoside, adenosine.
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1 | Q5A683 (/IMP) |
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Spleen development GO:0048536
The process whose specific outcome is the progression of the spleen over time, from its formation to the mature structure. The spleen is a large vascular lymphatic organ composed of white and red pulp, involved both in hemopoietic and immune system functions.
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1 | P06876 (/IMP) |
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Thymus development GO:0048538
The process whose specific outcome is the progression of the thymus over time, from its formation to the mature structure. The thymus is a symmetric bi-lobed organ involved primarily in the differentiation of immature to mature T cells, with unique vascular, nervous, epithelial, and lymphoid cell components.
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1 | P06876 (/IMP) |
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Embryonic digestive tract development GO:0048566
The process whose specific outcome is the progression of the gut over time, from its formation to the mature structure during embryonic development. The gut is the region of the digestive tract extending from the beginning of the intestines to the anus.
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1 | P06876 (/IMP) |
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Homeostasis of number of cells GO:0048872
Any biological process involved in the maintenance of the steady-state number of cells within a population of cells.
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1 | P06876 (/IMP) |
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Positive regulation of histone H3-K4 methylation GO:0051571
Any process that activates or increases the frequency, rate or extent of the covalent addition of a methyl group to the lysine at position 4 of histone H3.
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1 | P06876 (/ISO) |
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Positive regulation of histone H3-K9 methylation GO:0051574
Any process that activates or increases the frequency, rate or extent of the covalent addition of a methyl group to the lysine at position 9 of histone H3.
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1 | P06876 (/ISO) |
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Cellular response to interleukin-6 GO:0071354
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-6 stimulus.
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1 | P06876 (/IDA) |
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Positive regulation of purine nucleotide biosynthetic process by transcription from RNA polymerase II promoter GO:0100036
Any transcription from RNA polymerase II promoter process that positively_regulates purine nucleotide biosynthetic process
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1 | Q5A683 (/IMP) |
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Positive regulation of response to salt stress GO:1901002
Any process that activates or increases the frequency, rate or extent of response to salt stress.
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1 | Q0JHU7 (/IMP) |
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Positive regulation of response to water deprivation GO:1902584
Any process that activates or increases the frequency, rate or extent of response to water deprivation.
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1 | Q0JHU7 (/IMP) |
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PiRNA biosynthetic process GO:1990511
The chemical reactions and pathways resulting in the formation of piRNAs, Piwi-associated RNAs, a class of 24- to 30-nucleotide RNA derived from repeat or complex DNA sequence elements and processed by a Dicer-independent mechanism.
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1 | P51960 (/IDA) |
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Cellular response to leukemia inhibitory factor GO:1990830
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a leukemia inhibitory factor stimulus.
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1 | P06876 (/IEP) |
There are 12 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Chromatin GO:0000785
The ordered and organized complex of DNA, protein, and sometimes RNA, that forms the chromosome.
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6 | A0A2R8Q8E3 (/IDA) A0A2R8RYE8 (/IDA) F1QP24 (/IDA) F1QP25 (/IDA) Q6PBA4 (/IDA) Q9PTJ4 (/IDA) |
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Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
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5 | P06876 (/IDA) P22035 (/IDA) P22035 (/IDA) P51960 (/IDA) Q0JHU7 (/IDA) |
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Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
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5 | P06876 (/TAS) P10242 (/TAS) P10242 (/TAS) Q5SXM2 (/TAS) Q5SXM2 (/TAS) |
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Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
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3 | P34127 (/IC) Q5SXM2 (/IC) Q5SXM2 (/IC) |
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Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
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2 | P10243 (/ISS) Q05935 (/ISS) |
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Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
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2 | Q5SXM2 (/TAS) Q5SXM2 (/TAS) |
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Nuclear matrix GO:0016363
The dense fibrillar network lying on the inner side of the nuclear membrane.
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2 | P10242 (/NAS) P10242 (/NAS) |
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SnRNA-activating protein complex GO:0019185
A protein complex that recognizes the proximal sequence element of RNA polymerase II and III snRNA promoters.
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2 | Q5SXM2 (/IDA) Q5SXM2 (/IDA) |
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Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
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1 | P10243 (/NAS) |
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Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
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1 | P06876 (/IDA) |
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SnRNA-activating protein complex GO:0019185
A protein complex that recognizes the proximal sequence element of RNA polymerase II and III snRNA promoters.
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1 | Q8BP86 (/ISO) |
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SnRNA-activating protein complex GO:0019185
A protein complex that recognizes the proximal sequence element of RNA polymerase II and III snRNA promoters.
|
1 | Q8BP86 (/ISS) |
