The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:
"Beta-catenin-interacting ICAT
".
FunFam 1: beta-catenin-interacting protein 1
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 5 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
30 |
Q9JJN6 (/IPI)
Q9JJN6 (/IPI)
Q9JJN6 (/IPI)
Q9JJN6 (/IPI)
Q9JJN6 (/IPI)
Q9JJN6 (/IPI)
Q9JJN6 (/IPI)
Q9JJN6 (/IPI)
Q9NSA3 (/IPI)
Q9NSA3 (/IPI)
(20 more) |
|
Beta-catenin binding GO:0008013
Interacting selectively and non-covalently with the beta subunit of the catenin complex.
|
30 |
Q9JJN6 (/IPI)
Q9JJN6 (/IPI)
Q9JJN6 (/IPI)
Q9JJN6 (/IPI)
Q9JJN6 (/IPI)
Q9JJN6 (/IPI)
Q9JJN6 (/IPI)
Q9JJN6 (/IPI)
Q9NSA3 (/IPI)
Q9NSA3 (/IPI)
(20 more) |
|
Armadillo repeat domain binding GO:0070016
Interacting selectively and non-covalently with the armadillo repeat domain of a protein, an approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity protein armadillo. Arm-repeat proteins are involved in various processes, including intracellular signalling and cytoskeletal regulation.
|
22 |
Q9NSA3 (/IPI)
Q9NSA3 (/IPI)
Q9NSA3 (/IPI)
Q9NSA3 (/IPI)
Q9NSA3 (/IPI)
Q9NSA3 (/IPI)
Q9NSA3 (/IPI)
Q9NSA3 (/IPI)
Q9NSA3 (/IPI)
Q9NSA3 (/IPI)
(12 more) |
|
Beta-catenin binding GO:0008013
Interacting selectively and non-covalently with the beta subunit of the catenin complex.
|
8 | Q9JJN6 (/ISO) Q9JJN6 (/ISO) Q9JJN6 (/ISO) Q9JJN6 (/ISO) Q9JJN6 (/ISO) Q9JJN6 (/ISO) Q9JJN6 (/ISO) Q9JJN6 (/ISO) |
|
Armadillo repeat domain binding GO:0070016
Interacting selectively and non-covalently with the armadillo repeat domain of a protein, an approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity protein armadillo. Arm-repeat proteins are involved in various processes, including intracellular signalling and cytoskeletal regulation.
|
8 | Q9JJN6 (/ISO) Q9JJN6 (/ISO) Q9JJN6 (/ISO) Q9JJN6 (/ISO) Q9JJN6 (/ISO) Q9JJN6 (/ISO) Q9JJN6 (/ISO) Q9JJN6 (/ISO) |
There are 22 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Regulation of vascular permeability involved in acute inflammatory response GO:0002528
Any process that modulates the extent to which blood vessels can be pervaded by fluid contributing to an acute inflammatory response.
|
22 |
Q9NSA3 (/IMP)
Q9NSA3 (/IMP)
Q9NSA3 (/IMP)
Q9NSA3 (/IMP)
Q9NSA3 (/IMP)
Q9NSA3 (/IMP)
Q9NSA3 (/IMP)
Q9NSA3 (/IMP)
Q9NSA3 (/IMP)
Q9NSA3 (/IMP)
(12 more) |
|
Negative regulation of protein binding GO:0032091
Any process that stops, prevents, or reduces the frequency, rate or extent of protein binding.
|
22 |
Q9NSA3 (/IDA)
Q9NSA3 (/IDA)
Q9NSA3 (/IDA)
Q9NSA3 (/IDA)
Q9NSA3 (/IDA)
Q9NSA3 (/IDA)
Q9NSA3 (/IDA)
Q9NSA3 (/IDA)
Q9NSA3 (/IDA)
Q9NSA3 (/IDA)
(12 more) |
|
Negative regulation of DNA-binding transcription factor activity GO:0043433
Any process that stops, prevents, or reduces the frequency, rate or extent of the activity of a transcription factor, any factor involved in the initiation or regulation of transcription.
|
22 |
Q9NSA3 (/IMP)
Q9NSA3 (/IMP)
Q9NSA3 (/IMP)
Q9NSA3 (/IMP)
Q9NSA3 (/IMP)
Q9NSA3 (/IMP)
Q9NSA3 (/IMP)
Q9NSA3 (/IMP)
Q9NSA3 (/IMP)
Q9NSA3 (/IMP)
(12 more) |
|
Positive regulation of monocyte differentiation GO:0045657
Any process that activates or increases the frequency, rate or extent of monocyte differentiation.
|
22 |
Q9NSA3 (/IMP)
Q9NSA3 (/IMP)
Q9NSA3 (/IMP)
Q9NSA3 (/IMP)
Q9NSA3 (/IMP)
Q9NSA3 (/IMP)
Q9NSA3 (/IMP)
Q9NSA3 (/IMP)
Q9NSA3 (/IMP)
Q9NSA3 (/IMP)
(12 more) |
|
Positive regulation of osteoblast differentiation GO:0045669
Any process that activates or increases the frequency, rate or extent of osteoblast differentiation.
|
22 |
Q9NSA3 (/IMP)
Q9NSA3 (/IMP)
Q9NSA3 (/IMP)
Q9NSA3 (/IMP)
Q9NSA3 (/IMP)
Q9NSA3 (/IMP)
Q9NSA3 (/IMP)
Q9NSA3 (/IMP)
Q9NSA3 (/IMP)
Q9NSA3 (/IMP)
(12 more) |
|
Negative regulation of mesenchymal cell proliferation GO:0072201
Any process that decreases the frequency, rate or extent of mesenchymal cell proliferation. A mesenchymal cell is a cell that normally gives rise to other cells that are organized as three-dimensional masses, rather than sheets.
|
22 |
Q9NSA3 (/IMP)
Q9NSA3 (/IMP)
Q9NSA3 (/IMP)
Q9NSA3 (/IMP)
Q9NSA3 (/IMP)
Q9NSA3 (/IMP)
Q9NSA3 (/IMP)
Q9NSA3 (/IMP)
Q9NSA3 (/IMP)
Q9NSA3 (/IMP)
(12 more) |
|
Negative regulation of transcription by RNA polymerase II GO:0000122
Any process that stops, prevents, or reduces the frequency, rate or extent of transcription mediated by RNA polymerase II.
|
8 | Q9JJN6 (/IDA) Q9JJN6 (/IDA) Q9JJN6 (/IDA) Q9JJN6 (/IDA) Q9JJN6 (/IDA) Q9JJN6 (/IDA) Q9JJN6 (/IDA) Q9JJN6 (/IDA) |
|
Branching involved in ureteric bud morphogenesis GO:0001658
The process in which the branching structure of the ureteric bud is generated and organized. The ureteric bud is an epithelial tube that grows out from the metanephric duct. The bud elongates and branches to give rise to the ureter and kidney collecting tubules.
|
8 | Q9JJN6 (/IMP) Q9JJN6 (/IMP) Q9JJN6 (/IMP) Q9JJN6 (/IMP) Q9JJN6 (/IMP) Q9JJN6 (/IMP) Q9JJN6 (/IMP) Q9JJN6 (/IMP) |
|
Regulation of vascular permeability involved in acute inflammatory response GO:0002528
Any process that modulates the extent to which blood vessels can be pervaded by fluid contributing to an acute inflammatory response.
|
8 | Q9JJN6 (/ISO) Q9JJN6 (/ISO) Q9JJN6 (/ISO) Q9JJN6 (/ISO) Q9JJN6 (/ISO) Q9JJN6 (/ISO) Q9JJN6 (/ISO) Q9JJN6 (/ISO) |
|
Anterior/posterior pattern specification GO:0009952
The regionalization process in which specific areas of cell differentiation are determined along the anterior-posterior axis. The anterior-posterior axis is defined by a line that runs from the head or mouth of an organism to the tail or opposite end of the organism.
|
8 | Q9JJN6 (/IMP) Q9JJN6 (/IMP) Q9JJN6 (/IMP) Q9JJN6 (/IMP) Q9JJN6 (/IMP) Q9JJN6 (/IMP) Q9JJN6 (/IMP) Q9JJN6 (/IMP) |
|
Wnt signaling pathway GO:0016055
The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell and ending with a change in cell state.
|
8 | Q9JJN6 (/IPI) Q9JJN6 (/IPI) Q9JJN6 (/IPI) Q9JJN6 (/IPI) Q9JJN6 (/IPI) Q9JJN6 (/IPI) Q9JJN6 (/IPI) Q9JJN6 (/IPI) |
|
Negative regulation of Wnt signaling pathway GO:0030178
Any process that stops, prevents, or reduces the frequency, rate or extent of the Wnt signaling pathway.
|
8 | Q9JJN6 (/IDA) Q9JJN6 (/IDA) Q9JJN6 (/IDA) Q9JJN6 (/IDA) Q9JJN6 (/IDA) Q9JJN6 (/IDA) Q9JJN6 (/IDA) Q9JJN6 (/IDA) |
|
Negative regulation of protein complex assembly GO:0031333
Any process that stops, prevents, or reduces the frequency, rate or extent of protein complex assembly.
|
8 | Q9JJN6 (/IDA) Q9JJN6 (/IDA) Q9JJN6 (/IDA) Q9JJN6 (/IDA) Q9JJN6 (/IDA) Q9JJN6 (/IDA) Q9JJN6 (/IDA) Q9JJN6 (/IDA) |
|
Negative regulation of protein binding GO:0032091
Any process that stops, prevents, or reduces the frequency, rate or extent of protein binding.
|
8 | Q9JJN6 (/ISO) Q9JJN6 (/ISO) Q9JJN6 (/ISO) Q9JJN6 (/ISO) Q9JJN6 (/ISO) Q9JJN6 (/ISO) Q9JJN6 (/ISO) Q9JJN6 (/ISO) |
|
Negative regulation of DNA binding GO:0043392
Any process that stops or reduces the frequency, rate or extent of DNA binding. DNA binding is any process in which a gene product interacts selectively with DNA (deoxyribonucleic acid).
|
8 | Q9JJN6 (/IDA) Q9JJN6 (/IDA) Q9JJN6 (/IDA) Q9JJN6 (/IDA) Q9JJN6 (/IDA) Q9JJN6 (/IDA) Q9JJN6 (/IDA) Q9JJN6 (/IDA) |
|
Negative regulation of DNA-binding transcription factor activity GO:0043433
Any process that stops, prevents, or reduces the frequency, rate or extent of the activity of a transcription factor, any factor involved in the initiation or regulation of transcription.
|
8 | Q9JJN6 (/IDA) Q9JJN6 (/IDA) Q9JJN6 (/IDA) Q9JJN6 (/IDA) Q9JJN6 (/IDA) Q9JJN6 (/IDA) Q9JJN6 (/IDA) Q9JJN6 (/IDA) |
|
Negative regulation of DNA-binding transcription factor activity GO:0043433
Any process that stops, prevents, or reduces the frequency, rate or extent of the activity of a transcription factor, any factor involved in the initiation or regulation of transcription.
|
8 | Q9JJN6 (/ISO) Q9JJN6 (/ISO) Q9JJN6 (/ISO) Q9JJN6 (/ISO) Q9JJN6 (/ISO) Q9JJN6 (/ISO) Q9JJN6 (/ISO) Q9JJN6 (/ISO) |
|
Positive regulation of monocyte differentiation GO:0045657
Any process that activates or increases the frequency, rate or extent of monocyte differentiation.
|
8 | Q9JJN6 (/ISO) Q9JJN6 (/ISO) Q9JJN6 (/ISO) Q9JJN6 (/ISO) Q9JJN6 (/ISO) Q9JJN6 (/ISO) Q9JJN6 (/ISO) Q9JJN6 (/ISO) |
|
Positive regulation of osteoblast differentiation GO:0045669
Any process that activates or increases the frequency, rate or extent of osteoblast differentiation.
|
8 | Q9JJN6 (/ISO) Q9JJN6 (/ISO) Q9JJN6 (/ISO) Q9JJN6 (/ISO) Q9JJN6 (/ISO) Q9JJN6 (/ISO) Q9JJN6 (/ISO) Q9JJN6 (/ISO) |
|
Negative regulation of smooth muscle cell proliferation GO:0048662
Any process that stops, prevents or reduces the rate or extent of smooth muscle cell proliferation.
|
8 | Q9JJN6 (/IMP) Q9JJN6 (/IMP) Q9JJN6 (/IMP) Q9JJN6 (/IMP) Q9JJN6 (/IMP) Q9JJN6 (/IMP) Q9JJN6 (/IMP) Q9JJN6 (/IMP) |
|
Negative regulation of transcription initiation from RNA polymerase II promoter GO:0060633
Any process that decreases the rate, frequency or extent of a process involved in starting transcription from an RNA polymerase II promoter.
|
8 | Q9JJN6 (/IDA) Q9JJN6 (/IDA) Q9JJN6 (/IDA) Q9JJN6 (/IDA) Q9JJN6 (/IDA) Q9JJN6 (/IDA) Q9JJN6 (/IDA) Q9JJN6 (/IDA) |
|
Negative regulation of mesenchymal cell proliferation GO:0072201
Any process that decreases the frequency, rate or extent of mesenchymal cell proliferation. A mesenchymal cell is a cell that normally gives rise to other cells that are organized as three-dimensional masses, rather than sheets.
|
8 | Q9JJN6 (/ISO) Q9JJN6 (/ISO) Q9JJN6 (/ISO) Q9JJN6 (/ISO) Q9JJN6 (/ISO) Q9JJN6 (/ISO) Q9JJN6 (/ISO) Q9JJN6 (/ISO) |
There are 11 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
22 |
Q9NSA3 (/IDA)
Q9NSA3 (/IDA)
Q9NSA3 (/IDA)
Q9NSA3 (/IDA)
Q9NSA3 (/IDA)
Q9NSA3 (/IDA)
Q9NSA3 (/IDA)
Q9NSA3 (/IDA)
Q9NSA3 (/IDA)
Q9NSA3 (/IDA)
(12 more) |
|
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
|
22 |
Q9NSA3 (/TAS)
Q9NSA3 (/TAS)
Q9NSA3 (/TAS)
Q9NSA3 (/TAS)
Q9NSA3 (/TAS)
Q9NSA3 (/TAS)
Q9NSA3 (/TAS)
Q9NSA3 (/TAS)
Q9NSA3 (/TAS)
Q9NSA3 (/TAS)
(12 more) |
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
22 |
Q9NSA3 (/IDA)
Q9NSA3 (/IDA)
Q9NSA3 (/IDA)
Q9NSA3 (/IDA)
Q9NSA3 (/IDA)
Q9NSA3 (/IDA)
Q9NSA3 (/IDA)
Q9NSA3 (/IDA)
Q9NSA3 (/IDA)
Q9NSA3 (/IDA)
(12 more) |
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
22 |
Q9NSA3 (/IDA)
Q9NSA3 (/IDA)
Q9NSA3 (/IDA)
Q9NSA3 (/IDA)
Q9NSA3 (/IDA)
Q9NSA3 (/IDA)
Q9NSA3 (/IDA)
Q9NSA3 (/IDA)
Q9NSA3 (/IDA)
Q9NSA3 (/IDA)
(12 more) |
|
Beta-catenin destruction complex GO:0030877
A cytoplasmic protein complex containing glycogen synthase kinase-3-beta (GSK-3-beta), the adenomatous polyposis coli protein (APC), and the scaffolding protein axin, among others; phosphorylates beta-catenin, targets it for degradation by the proteasome.
|
22 |
Q9NSA3 (/IDA)
Q9NSA3 (/IDA)
Q9NSA3 (/IDA)
Q9NSA3 (/IDA)
Q9NSA3 (/IDA)
Q9NSA3 (/IDA)
Q9NSA3 (/IDA)
Q9NSA3 (/IDA)
Q9NSA3 (/IDA)
Q9NSA3 (/IDA)
(12 more) |
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
8 | Q9JJN6 (/ISO) Q9JJN6 (/ISO) Q9JJN6 (/ISO) Q9JJN6 (/ISO) Q9JJN6 (/ISO) Q9JJN6 (/ISO) Q9JJN6 (/ISO) Q9JJN6 (/ISO) |
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
8 | Q9JJN6 (/TAS) Q9JJN6 (/TAS) Q9JJN6 (/TAS) Q9JJN6 (/TAS) Q9JJN6 (/TAS) Q9JJN6 (/TAS) Q9JJN6 (/TAS) Q9JJN6 (/TAS) |
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
8 | Q9JJN6 (/ISO) Q9JJN6 (/ISO) Q9JJN6 (/ISO) Q9JJN6 (/ISO) Q9JJN6 (/ISO) Q9JJN6 (/ISO) Q9JJN6 (/ISO) Q9JJN6 (/ISO) |
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
8 | Q9JJN6 (/TAS) Q9JJN6 (/TAS) Q9JJN6 (/TAS) Q9JJN6 (/TAS) Q9JJN6 (/TAS) Q9JJN6 (/TAS) Q9JJN6 (/TAS) Q9JJN6 (/TAS) |
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
8 | Q9JJN6 (/ISO) Q9JJN6 (/ISO) Q9JJN6 (/ISO) Q9JJN6 (/ISO) Q9JJN6 (/ISO) Q9JJN6 (/ISO) Q9JJN6 (/ISO) Q9JJN6 (/ISO) |
|
Beta-catenin destruction complex GO:0030877
A cytoplasmic protein complex containing glycogen synthase kinase-3-beta (GSK-3-beta), the adenomatous polyposis coli protein (APC), and the scaffolding protein axin, among others; phosphorylates beta-catenin, targets it for degradation by the proteasome.
|
8 | Q9JJN6 (/ISO) Q9JJN6 (/ISO) Q9JJN6 (/ISO) Q9JJN6 (/ISO) Q9JJN6 (/ISO) Q9JJN6 (/ISO) Q9JJN6 (/ISO) Q9JJN6 (/ISO) |
