CATH Superfamily 1.10.10.10

FunFam 27: Heat shock transcription factor 1

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 67 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

GO Term	Annotations	Evidence
Sequence-specific DNA binding GO:0043565 Interacting selectively and non-covalently with DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding.	22	A0A060W590 (/IDA) A0A096MK39 (/IDA) A0A2R8QAT5 (/IDA) D0VYS2 (/IDA) F6P697 (/IDA) P38529 (/IDA) P38531 (/IDA) P38532 (/IDA) P38532 (/IDA) P38533 (/IDA) (12 more)
DNA-binding transcription factor activity, RNA polymerase II-specific GO:0000981 A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.	6	Q00613 (/ISA) Q03933 (/ISA) Q03933 (/ISA) Q03933 (/ISA) Q9ULV5 (/ISA) Q9ULV5 (/ISA)
DNA-binding transcription factor activity, RNA polymerase II-specific GO:0000981 A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.	6	Q00613 (/ISM) Q03933 (/ISM) Q03933 (/ISM) Q03933 (/ISM) Q9ULV5 (/ISM) Q9ULV5 (/ISM)
DNA-binding transcription factor activity, RNA polymerase II-specific GO:0000981 A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.	6	Q00613 (/NAS) Q03933 (/NAS) Q03933 (/NAS) Q03933 (/NAS) Q9ULV5 (/NAS) Q9ULV5 (/NAS)
DNA binding GO:0003677 Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).	6	P38529 (/IDA) P38531 (/IDA) P38532 (/IDA) P38532 (/IDA) P38533 (/IDA) Q00613 (/IDA)
DNA-binding transcription factor activity GO:0003700 A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons.	6	Q00613 (/TAS) Q03933 (/TAS) Q03933 (/TAS) Q03933 (/TAS) Q9ULV5 (/TAS) Q9ULV5 (/TAS)
Protein homodimerization activity GO:0042803 Interacting selectively and non-covalently with an identical protein to form a homodimer.	6	A0A1D5PC94 (/IDA) P38529 (/IDA) P38530 (/IDA) P38531 (/IDA) P38533 (/IDA) Q76M53 (/IDA)
RNA polymerase II proximal promoter sequence-specific DNA binding GO:0000978 Interacting selectively and non-covalently with a specific upstream regulatory DNA sequence (transcription factor recognition sequence or binding site) located in the proximal promoter of a gene transcribed by RNA polymerase II. The proximal promoter is in cis with and relatively close to the core promoter.	5	P38532 (/IDA) P38532 (/IDA) P38533 (/IDA) Q00613 (/IDA) Q02953 (/IDA)
Protein binding GO:0005515 Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).	5	P38531 (/IPI) Q00613 (/IPI) Q03933 (/IPI) Q03933 (/IPI) Q03933 (/IPI)
Heat shock protein binding GO:0031072 Interacting selectively and non-covalently with a heat shock protein, any protein synthesized or activated in response to heat shock.	5	P38529 (/ISS) P38532 (/ISS) P38532 (/ISS) Q08DJ8 (/ISS) Q08DJ8 (/ISS)
Chromatin DNA binding GO:0031490 Interacting selectively and non-covalently with DNA that is assembled into chromatin.	5	P38529 (/ISS) P38532 (/ISS) P38532 (/ISS) Q08DJ8 (/ISS) Q08DJ8 (/ISS)
Protein self-association GO:0043621 Interacting selectively and non-covalently with a domain within the same polypeptide.	5	P38529 (/ISS) P38532 (/ISS) P38532 (/ISS) Q08DJ8 (/ISS) Q08DJ8 (/ISS)
Promoter-specific chromatin binding GO:1990841 Interacting selectively and non-covalently with a section of chromatin that is associated with gene promoter sequences of DNA.	5	P38529 (/ISS) P38532 (/ISS) P38532 (/ISS) Q08DJ8 (/ISS) Q08DJ8 (/ISS)
Core promoter sequence-specific DNA binding GO:0001046 Interacting selectively and non-covalently with a sequence of DNA that is part of a core promoter region. The core promoter is composed of the transcription start site and binding sites for the RNA polymerase and the basal transcription machinery. The transcribed region might be described as a gene, cistron, or operon.	4	A0A1D5PC94 (/IDA) P38529 (/IDA) P38530 (/IDA) P38531 (/IDA)
RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding GO:0001162 Interacting selectively and non-covalently with an RNA polymerase II intronic DNA sequence that regulates the transcription of the transcript it is contained within.	4	Q00613 (/IDA) Q03933 (/IDA) Q03933 (/IDA) Q03933 (/IDA)
Identical protein binding GO:0042802 Interacting selectively and non-covalently with an identical protein or proteins.	4	P38532 (/ISS) P38532 (/ISS) Q08DJ8 (/ISS) Q08DJ8 (/ISS)
Protein heterodimerization activity GO:0046982 Interacting selectively and non-covalently with a nonidentical protein to form a heterodimer.	4	P38532 (/ISS) P38532 (/ISS) Q08DJ8 (/ISS) Q08DJ8 (/ISS)
Hsp90 protein binding GO:0051879 Interacting selectively and non-covalently with Hsp90 proteins, any of a group of heat shock proteins around 90kDa in size.	4	P38532 (/ISS) P38532 (/ISS) Q08DJ8 (/ISS) Q08DJ8 (/ISS)
Translation elongation factor binding GO:0061770 Interacting selectively and non-covalently with a translation elongation factor, any polypeptide factor involved in the peptide elongation in ribosome-mediated translation.	4	P38532 (/ISS) P38532 (/ISS) Q08DJ8 (/ISS) Q08DJ8 (/ISS)
RNA polymerase II regulatory region sequence-specific DNA binding GO:0000977 Interacting selectively and non-covalently with a specific sequence of DNA that is part of a regulatory region that controls the transcription of a gene or cistron by RNA polymerase II.	3	Q03933 (/IDA) Q03933 (/IDA) Q03933 (/IDA)
RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding GO:0001162 Interacting selectively and non-covalently with an RNA polymerase II intronic DNA sequence that regulates the transcription of the transcript it is contained within.	3	P38532 (/ISO) P38532 (/ISO) P38533 (/ISO)
DNA-binding transcription activator activity, RNA polymerase II-specific GO:0001228 A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to activate or increase transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.	3	Q03933 (/IDA) Q03933 (/IDA) Q03933 (/IDA)
DNA binding GO:0003677 Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).	3	P10961 (/IMP) P10961 (/IMP) P22121 (/IMP)
DNA binding GO:0003677 Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).	3	P38529 (/ISS) Q08DJ8 (/ISS) Q08DJ8 (/ISS)
Transcription coactivator activity GO:0003713 A protein or a member of a complex that interacts specifically and non-covalently with a DNA-bound DNA-binding transcription factor to activate the transcription of specific genes. Coactivators often act by altering chromatin structure and modifications. For example, one class of transcription coregulators modifies chromatin structure through covalent modification of histones. A second ATP-dependent class modifies the conformation of chromatin. Another type of coregulator activity is the bridging of a DNA-binding transcription factor to the basal transcription machinery. The Mediator complex, which bridges transcription factors and RNA polymerase, is also a transcription coactivator.	3	Q03933 (/TAS) Q03933 (/TAS) Q03933 (/TAS)
Sequence-specific DNA binding GO:0043565 Interacting selectively and non-covalently with DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding.	3	P38529 (/ISS) Q08DJ8 (/ISS) Q08DJ8 (/ISS)
RNA polymerase II proximal promoter sequence-specific DNA binding GO:0000978 Interacting selectively and non-covalently with a specific upstream regulatory DNA sequence (transcription factor recognition sequence or binding site) located in the proximal promoter of a gene transcribed by RNA polymerase II. The proximal promoter is in cis with and relatively close to the core promoter.	2	P38532 (/ISO) P38532 (/ISO)
Proximal promoter sequence-specific DNA binding GO:0000987 Interacting selectively and non-covalently with a specific upstream regulatory DNA sequence (transcription factor recognition sequence or binding site) located in the proximal promoter. The proximal promoter is in cis with and relatively close to the core promoter.	2	Q76M53 (/IDA) Q76M54 (/IDA)
DNA-binding transcription repressor activity, RNA polymerase II-specific GO:0001227 A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to repress or decrease transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.	2	P38532 (/ISO) P38532 (/ISO)
DNA binding GO:0003677 Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).	2	P38532 (/ISO) P38532 (/ISO)
Chromatin binding GO:0003682 Interacting selectively and non-covalently with chromatin, the network of fibers of DNA, protein, and sometimes RNA, that make up the chromosomes of the eukaryotic nucleus during interphase.	2	P38532 (/IDA) P38532 (/IDA)
DNA-binding transcription factor activity GO:0003700 A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons.	2	P10961 (/IDA) P10961 (/IDA)
Transcription corepressor activity GO:0003714 A protein or a member of a complex that interacts specifically and non-covalently with a DNA-bound DNA-binding transcription factor to repress the transcription of specific genes. Corepressors often act by altering chromatin structure and modifications. For example, one class of transcription coregulators modifies chromatin structure through covalent modification of histones. A second ATP-dependent class modifies the conformation of chromatin. A third class occludes DNA-binding transcription factor protein-protein interaction domains. A fourth class of corepressors prevents interactions of DNA bound DNA-binding transcription factor with coactivators.	2	Q9ULV5 (/TAS) Q9ULV5 (/TAS)
Protein kinase binding GO:0019901 Interacting selectively and non-covalently with a protein kinase, any enzyme that catalyzes the transfer of a phosphate group, usually from ATP, to a protein substrate.	2	P38532 (/ISO) P38532 (/ISO)
Protein phosphatase binding GO:0019903 Interacting selectively and non-covalently with any protein phosphatase.	2	Q9R0L1 (/ISO) Q9R0L1 (/ISO)
Heat shock protein binding GO:0031072 Interacting selectively and non-covalently with a heat shock protein, any protein synthesized or activated in response to heat shock.	2	F1MAF1 (/IDA) Q00613 (/IDA)
Heat shock protein binding GO:0031072 Interacting selectively and non-covalently with a heat shock protein, any protein synthesized or activated in response to heat shock.	2	P38532 (/ISO) P38532 (/ISO)
Chromatin DNA binding GO:0031490 Interacting selectively and non-covalently with DNA that is assembled into chromatin.	2	D0VYS2 (/IDA) Q00613 (/IDA)
Chromatin DNA binding GO:0031490 Interacting selectively and non-covalently with DNA that is assembled into chromatin.	2	P38532 (/ISO) P38532 (/ISO)
SUMO binding GO:0032183 Interacting selectively and non-covalently with the small ubiquitin-like protein SUMO.	2	A0A060W590 (/IMP) Q8AWA0 (/IMP)
Activating transcription factor binding GO:0033613 Interacting selectively and non-covalently with an activating transcription factor, any protein whose activity is required to initiate or upregulate transcription.	2	Q76M53 (/IDA) Q76M54 (/IDA)
Identical protein binding GO:0042802 Interacting selectively and non-covalently with an identical protein or proteins.	2	P38532 (/ISO) P38532 (/ISO)
Sequence-specific DNA binding GO:0043565 Interacting selectively and non-covalently with DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding.	2	P10961 (/HDA) P10961 (/HDA)
Sequence-specific DNA binding GO:0043565 Interacting selectively and non-covalently with DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding.	2	P38532 (/ISO) P38532 (/ISO)
Protein self-association GO:0043621 Interacting selectively and non-covalently with a domain within the same polypeptide.	2	P38532 (/ISO) P38532 (/ISO)
Protein heterodimerization activity GO:0046982 Interacting selectively and non-covalently with a nonidentical protein to form a heterodimer.	2	P38532 (/ISO) P38532 (/ISO)
Hsp90 protein binding GO:0051879 Interacting selectively and non-covalently with Hsp90 proteins, any of a group of heat shock proteins around 90kDa in size.	2	P38532 (/ISO) P38532 (/ISO)
Translation elongation factor binding GO:0061770 Interacting selectively and non-covalently with a translation elongation factor, any polypeptide factor involved in the peptide elongation in ribosome-mediated translation.	2	P38532 (/ISO) P38532 (/ISO)
STAT family protein binding GO:0097677 Interacting selectively and non-covalently with any member of the signal transducers and activators of transcription (STAT) protein family. STATs are, as the name indicates, both signal transducers and transcription factors. STATs are activated by cytokines and some growth factors and thus control important biological processes including cell growth, cell differentiation, apoptosis and immune responses.	2	P38532 (/ISO) P38532 (/ISO)
Sequence-specific single stranded DNA binding GO:0098847 Interacting selectively and non-covalently with single-stranded DNA of a specific nucleotide composition.	2	P38532 (/ISO) P38532 (/ISO)
Promoter-specific chromatin binding GO:1990841 Interacting selectively and non-covalently with a section of chromatin that is associated with gene promoter sequences of DNA.	2	F1MAF1 (/IDA) Q00613 (/IDA)
Promoter-specific chromatin binding GO:1990841 Interacting selectively and non-covalently with a section of chromatin that is associated with gene promoter sequences of DNA.	2	P38532 (/ISO) P38532 (/ISO)
RNA polymerase II regulatory region sequence-specific DNA binding GO:0000977 Interacting selectively and non-covalently with a specific sequence of DNA that is part of a regulatory region that controls the transcription of a gene or cistron by RNA polymerase II.	1	P38533 (/ISO)
DNA-binding transcription factor activity, RNA polymerase II-specific GO:0000981 A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.	1	Q02953 (/IDA)
DNA-binding transcription repressor activity, RNA polymerase II-specific GO:0001227 A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to repress or decrease transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.	1	Q00613 (/IDA)
DNA-binding transcription activator activity, RNA polymerase II-specific GO:0001228 A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to activate or increase transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.	1	Q02953 (/IMP)
DNA-binding transcription activator activity, RNA polymerase II-specific GO:0001228 A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to activate or increase transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.	1	P38533 (/ISO)
DNA-binding transcription factor activity GO:0003700 A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons.	1	Q5AQ33 (/ISO)
Protein kinase binding GO:0019901 Interacting selectively and non-covalently with a protein kinase, any enzyme that catalyzes the transfer of a phosphate group, usually from ATP, to a protein substrate.	1	Q00613 (/IPI)
Identical protein binding GO:0042802 Interacting selectively and non-covalently with an identical protein or proteins.	1	Q00613 (/IDA)
Identical protein binding GO:0042802 Interacting selectively and non-covalently with an identical protein or proteins.	1	Q00613 (/IPI)
Protein self-association GO:0043621 Interacting selectively and non-covalently with a domain within the same polypeptide.	1	Q00613 (/IDA)
Protein heterodimerization activity GO:0046982 Interacting selectively and non-covalently with a nonidentical protein to form a heterodimer.	1	Q00613 (/IDA)
Hsp90 protein binding GO:0051879 Interacting selectively and non-covalently with Hsp90 proteins, any of a group of heat shock proteins around 90kDa in size.	1	Q00613 (/IDA)
Translation elongation factor binding GO:0061770 Interacting selectively and non-covalently with a translation elongation factor, any polypeptide factor involved in the peptide elongation in ribosome-mediated translation.	1	Q00613 (/IDA)
STAT family protein binding GO:0097677 Interacting selectively and non-covalently with any member of the signal transducers and activators of transcription (STAT) protein family. STATs are, as the name indicates, both signal transducers and transcription factors. STATs are activated by cytokines and some growth factors and thus control important biological processes including cell growth, cell differentiation, apoptosis and immune responses.	1	F1MAF1 (/IPI)
Sequence-specific single stranded DNA binding GO:0098847 Interacting selectively and non-covalently with single-stranded DNA of a specific nucleotide composition.	1	F1MAF1 (/IDA)

There are 169 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

GO Term	Annotations	Evidence
Response to heat GO:0009408 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism.	9	F1MAF1 (/IDA) F6P697 (/IDA) P38529 (/IDA) P38531 (/IDA) Q1LXV0 (/IDA) Q8UWM7 (/IDA) Q90YY9 (/IDA) Q9IAS0 (/IDA) Q9IAS1 (/IDA)
Protein homotrimerization GO:0070207 The formation of a protein homotrimer, a macromolecular structure consisting of three noncovalently associated identical subunits.	9	A0A1D5PC94 (/IDA) P38529 (/IDA) P38530 (/IDA) P38531 (/IDA) Q00613 (/IDA) Q76M53 (/IDA) Q76M54 (/IDA) Q9R0L1 (/IDA) Q9R0L1 (/IDA)
Lens development in camera-type eye GO:0002088 The process whose specific outcome is the progression of the lens over time, from its formation to the mature structure. The lens is a transparent structure in the eye through which light is focused onto the retina. An example of this process is found in Mus musculus.	6	F6P697 (/IMP) Q1LXV0 (/IMP) Q8UWM7 (/IMP) Q90YY9 (/IMP) Q9IAS0 (/IMP) Q9IAS1 (/IMP)
Positive regulation of transcription by RNA polymerase II GO:0045944 Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.	6	D0VYS2 (/IDA) Q00613 (/IDA) Q02953 (/IDA) Q03933 (/IDA) Q03933 (/IDA) Q03933 (/IDA)
Negative regulation of transcription by RNA polymerase II GO:0000122 Any process that stops, prevents, or reduces the frequency, rate or extent of transcription mediated by RNA polymerase II.	5	P38529 (/ISS) P38532 (/ISS) P38532 (/ISS) Q08DJ8 (/ISS) Q08DJ8 (/ISS)
MAPK cascade GO:0000165 An intracellular protein kinase cascade containing at least a MAPK, a MAPKK and a MAP3K. The cascade can also contain an additional tiers: the upstream MAP4K. The kinases in each tier phosphorylate and activate the kinase in the downstream tier to transmit a signal within a cell.	5	P38529 (/ISS) P38532 (/ISS) P38532 (/ISS) Q08DJ8 (/ISS) Q08DJ8 (/ISS)
Positive regulation of cell population proliferation GO:0008284 Any process that activates or increases the rate or extent of cell proliferation.	5	P38529 (/IMP) P38531 (/IMP) Q00613 (/IMP) Q9R0L1 (/IMP) Q9R0L1 (/IMP)
Positive regulation of cell population proliferation GO:0008284 Any process that activates or increases the rate or extent of cell proliferation.	5	P38529 (/ISS) P38532 (/ISS) P38532 (/ISS) Q08DJ8 (/ISS) Q08DJ8 (/ISS)
Regulation of protein heterodimerization activity GO:0043497 Any process that modulates the frequency, rate or extent of protein heterodimerization, interacting selectively with a nonidentical protein to form a heterodimer.	5	P38529 (/ISS) P38532 (/ISS) P38532 (/ISS) Q08DJ8 (/ISS) Q08DJ8 (/ISS)
Positive regulation of mitotic cell cycle GO:0045931 Any process that activates or increases the rate or extent of progression through the mitotic cell cycle.	5	P38529 (/ISS) P38532 (/ISS) P38532 (/ISS) Q08DJ8 (/ISS) Q08DJ8 (/ISS)
Positive regulation of transcription by RNA polymerase II GO:0045944 Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.	5	P10961 (/IMP) P10961 (/IMP) Q5AQ33 (/IMP) Q9R0L1 (/IMP) Q9R0L1 (/IMP)
Positive regulation of transcription by RNA polymerase II GO:0045944 Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.	5	P38529 (/ISS) P38532 (/ISS) P38532 (/ISS) Q08DJ8 (/ISS) Q08DJ8 (/ISS)
Protein homooligomerization GO:0051260 The process of creating protein oligomers, compounds composed of a small number, usually between three and ten, of identical component monomers. Oligomers may be formed by the polymerization of a number of monomers or the depolymerization of a large protein polymer.	5	P38529 (/ISS) P38532 (/ISS) P38532 (/ISS) Q08DJ8 (/ISS) Q08DJ8 (/ISS)
Positive regulation of transcription from RNA polymerase II promoter in response to heat stress GO:0061408 Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism.	5	P38529 (/ISS) P38532 (/ISS) P38532 (/ISS) Q08DJ8 (/ISS) Q08DJ8 (/ISS)
Protein homotrimerization GO:0070207 The formation of a protein homotrimer, a macromolecular structure consisting of three noncovalently associated identical subunits.	5	P38529 (/ISS) P38532 (/ISS) P38532 (/ISS) Q08DJ8 (/ISS) Q08DJ8 (/ISS)
Cellular response to cadmium ion GO:0071276 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cadmium (Cd) ion stimulus.	5	P38529 (/ISS) P38532 (/ISS) P38532 (/ISS) Q08DJ8 (/ISS) Q08DJ8 (/ISS)
Cellular response to gamma radiation GO:0071480 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gamma radiation stimulus. Gamma radiation is a form of electromagnetic radiation (EMR) or light emission of a specific frequency produced from sub-atomic particle interaction, such as electron-positron annihilation and radioactive decay. Gamma rays are generally characterized as EMR having the highest frequency and energy, and also the shortest wavelength, within the electromagnetic radiation spectrum.	5	P38529 (/ISS) P38532 (/ISS) P38532 (/ISS) Q08DJ8 (/ISS) Q08DJ8 (/ISS)
Positive regulation of mRNA polyadenylation GO:1900365 Any process that activates or increases the frequency, rate or extent of mRNA polyadenylation.	5	P38529 (/ISS) P38532 (/ISS) P38532 (/ISS) Q08DJ8 (/ISS) Q08DJ8 (/ISS)
Negative regulation of double-strand break repair via nonhomologous end joining GO:2001033 Any process that stops, prevents or reduces the frequency, rate or extent of double-strand break repair via nonhomologous end joining.	5	P38529 (/ISS) P38532 (/ISS) P38532 (/ISS) Q08DJ8 (/ISS) Q08DJ8 (/ISS)
Response to heat GO:0009408 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism.	4	P10961 (/IMP) P10961 (/IMP) P38532 (/IMP) P38532 (/IMP)
Cellular response to heat GO:0034605 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism.	4	D0VYS2 (/IDA) P38529 (/IDA) P38531 (/IDA) Q00613 (/IDA)
Cellular response to heat GO:0034605 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism.	4	P38532 (/ISS) P38532 (/ISS) Q08DJ8 (/ISS) Q08DJ8 (/ISS)
Cellular response to unfolded protein GO:0034620 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an unfolded protein stimulus.	4	P38532 (/ISS) P38532 (/ISS) Q08DJ8 (/ISS) Q08DJ8 (/ISS)
Cellular protein-containing complex assembly GO:0034622 The aggregation, arrangement and bonding together of a set of components to form a protein complex, occurring at the level of an individual cell.	4	P38532 (/ISS) P38532 (/ISS) Q08DJ8 (/ISS) Q08DJ8 (/ISS)
Cellular response to copper ion GO:0071280 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a copper ion stimulus.	4	P38532 (/ISS) P38532 (/ISS) Q08DJ8 (/ISS) Q08DJ8 (/ISS)
Cellular response to diamide GO:0072738 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a diamide (N,N,N',N'-tetramethyldiazene-1,2-dicarboxamide) stimulus.	4	P38532 (/ISS) P38532 (/ISS) Q08DJ8 (/ISS) Q08DJ8 (/ISS)
Regulation of cellular response to heat GO:1900034 Any process that modulates the frequency, rate or extent of cellular response to heat.	4	P38532 (/ISS) P38532 (/ISS) Q08DJ8 (/ISS) Q08DJ8 (/ISS)
Cellular response to sodium arsenite GO:1903936 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a sodium arsenite stimulus.	4	P38532 (/ISS) P38532 (/ISS) Q08DJ8 (/ISS) Q08DJ8 (/ISS)
Regulation of transcription, DNA-templated GO:0006355 Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.	3	F1MAF1 (/TAS) Q9ULV5 (/TAS) Q9ULV5 (/TAS)
Transcription by RNA polymerase II GO:0006366 The synthesis of RNA from a DNA template by RNA polymerase II (RNAP II), originating at an RNA polymerase II promoter. Includes transcription of messenger RNA (mRNA) and certain small nuclear RNAs (snRNAs).	3	Q03933 (/TAS) Q03933 (/TAS) Q03933 (/TAS)
Response to light stimulus GO:0009416 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a light stimulus, electromagnetic radiation of wavelengths classified as infrared, visible or ultraviolet light.	3	A0A1D5PC94 (/IDA) P38529 (/IDA) P38530 (/IDA)
Positive regulation of gene expression GO:0010628 Any process that increases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.	3	F1MAF1 (/IMP) P38529 (/IMP) P38531 (/IMP)
Cellular response to heat GO:0034605 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism.	3	F1MAF1 (/IMP) Q00613 (/IMP) Q5AQ33 (/IMP)
Positive regulation of transcription by RNA polymerase II GO:0045944 Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.	3	P38532 (/ISO) P38532 (/ISO) P38533 (/ISO)
Negative regulation of transcription by RNA polymerase II GO:0000122 Any process that stops, prevents, or reduces the frequency, rate or extent of transcription mediated by RNA polymerase II.	2	Q9R0L1 (/IMP) Q9R0L1 (/IMP)
Negative regulation of transcription by RNA polymerase II GO:0000122 Any process that stops, prevents, or reduces the frequency, rate or extent of transcription mediated by RNA polymerase II.	2	P38532 (/ISO) P38532 (/ISO)
MAPK cascade GO:0000165 An intracellular protein kinase cascade containing at least a MAPK, a MAPKK and a MAP3K. The cascade can also contain an additional tiers: the upstream MAP4K. The kinases in each tier phosphorylate and activate the kinase in the downstream tier to transmit a signal within a cell.	2	P38532 (/ISO) P38532 (/ISO)
Eye development GO:0001654 The process whose specific outcome is the progression of the eye over time, from its formation to the mature structure. The eye is the organ of sight.	2	Q9R0L1 (/IMP) Q9R0L1 (/IMP)
In utero embryonic development GO:0001701 The process whose specific outcome is the progression of the embryo in the uterus over time, from formation of the zygote in the oviduct, to birth. An example of this process is found in Mus musculus.	2	P38532 (/IMP) P38532 (/IMP)
Embryonic placenta development GO:0001892 The embryonically driven process whose specific outcome is the progression of the placenta over time, from its formation to the mature structure. The placenta is an organ of metabolic interchange between fetus and mother, partly of embryonic origin and partly of maternal origin.	2	P38532 (/IMP) P38532 (/IMP)
Lens morphogenesis in camera-type eye GO:0002089 The process in which the anatomical structures of the lens are generated and organized. The lens is a transparent structure in the eye through which light is focused onto the retina. An example of this process is found in Mus musculus.	2	A0A2R8QAT5 (/IMP) Q5CZP2 (/IMP)
Regulation of transcription by RNA polymerase II GO:0006357 Any process that modulates the frequency, rate or extent of transcription mediated by RNA polymerase II.	2	P10961 (/IDA) P10961 (/IDA)
Protein phosphorylation GO:0006468 The process of introducing a phosphate group on to a protein.	2	P38532 (/IDA) P38532 (/IDA)
Defense response GO:0006952 Reactions, triggered in response to the presence of a foreign body or the occurrence of an injury, which result in restriction of damage to the organism attacked or prevention/recovery from the infection caused by the attack.	2	P38532 (/ISO) P38532 (/ISO)
Female meiotic nuclear division GO:0007143 A cell cycle process by which the cell nucleus divides as part of a meiotic cell cycle in the female germline.	2	P38532 (/IMP) P38532 (/IMP)
Spermatogenesis GO:0007283 The process of formation of spermatozoa, including spermatocytogenesis and spermiogenesis.	2	P38532 (/IGI) P38532 (/IGI)
Visual perception GO:0007601 The series of events required for an organism to receive a visual stimulus, convert it to a molecular signal, and recognize and characterize the signal. Visual stimuli are detected in the form of photons and are processed to form an image.	2	Q9R0L1 (/IMP) Q9R0L1 (/IMP)
Positive regulation of cell population proliferation GO:0008284 Any process that activates or increases the rate or extent of cell proliferation.	2	Q9R0L1 (/IGI) Q9R0L1 (/IGI)
Positive regulation of cell population proliferation GO:0008284 Any process that activates or increases the rate or extent of cell proliferation.	2	P38532 (/ISO) P38532 (/ISO)
Negative regulation of cell population proliferation GO:0008285 Any process that stops, prevents or reduces the rate or extent of cell proliferation.	2	P38532 (/IGI) P38532 (/IGI)
MRNA transcription GO:0009299 The cellular synthesis of messenger RNA (mRNA) from a DNA template.	2	P38532 (/ISO) P38532 (/ISO)
Response to heat GO:0009408 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism.	2	P38532 (/ISO) P38532 (/ISO)
Response to organonitrogen compound GO:0010243 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organonitrogen stimulus. An organonitrogen compound is formally a compound containing at least one carbon-nitrogen bond.	2	A0A1D5PC94 (/IDA) P38530 (/IDA)
Response to organonitrogen compound GO:0010243 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organonitrogen stimulus. An organonitrogen compound is formally a compound containing at least one carbon-nitrogen bond.	2	A0A1D5PC94 (/IMP) P38530 (/IMP)
Positive regulation of gene expression GO:0010628 Any process that increases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.	2	A0A060W590 (/IDA) Q8AWA0 (/IDA)
Positive regulation of gene expression GO:0010628 Any process that increases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.	2	P38532 (/ISO) P38532 (/ISO)
Negative regulation of gene expression GO:0010629 Any process that decreases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.	2	P38532 (/ISO) P38532 (/ISO)
Negative regulation of cardiac muscle cell apoptotic process GO:0010667 Any process that decreases the rate or extent of cardiac cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a cardiac muscle cell and result in its death.	2	P38532 (/ISO) P38532 (/ISO)
Response to organic cyclic compound GO:0014070 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organic cyclic compound stimulus.	2	A0A1D5PC94 (/IDA) P38530 (/IDA)
Response to organic cyclic compound GO:0014070 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organic cyclic compound stimulus.	2	A0A1D5PC94 (/IMP) P38530 (/IMP)
Negative regulation of protein ubiquitination GO:0031397 Any process that stops, prevents, or reduces the frequency, rate or extent of the addition of ubiquitin groups to a protein.	2	A0A1D5PC94 (/IMP) P38530 (/IMP)
Positive regulation of deoxyribonuclease activity GO:0032077 Any process that activates or increases the frequency, rate or extent of deoxyribonuclease activity, the hydrolysis of ester linkages within deoxyribonucleic acid.	2	A0A2R8QAT5 (/IMP) Q5CZP2 (/IMP)
Response to estradiol GO:0032355 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of stimulus by estradiol, a C18 steroid hormone hydroxylated at C3 and C17 that acts as a potent estrogen.	2	P38532 (/ISO) P38532 (/ISO)
Response to lipopolysaccharide GO:0032496 Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipopolysaccharide stimulus; lipopolysaccharide is a major component of the cell wall of gram-negative bacteria.	2	P38532 (/IMP) P38532 (/IMP)
Negative regulation of tumor necrosis factor production GO:0032720 Any process that stops, prevents, or reduces the frequency, rate, or extent of tumor necrosis factor production.	2	P38532 (/IMP) P38532 (/IMP)
Histone H3-K9 demethylation GO:0033169 The modification of histone H3 by the removal of a methyl group from lysine at position 9 of the histone.	2	Q9R0L1 (/IDA) Q9R0L1 (/IDA)
Response to testosterone GO:0033574 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a testosterone stimulus.	2	P38532 (/ISO) P38532 (/ISO)
Cellular response to heat GO:0034605 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism.	2	P38532 (/ISO) P38532 (/ISO)
Cellular response to unfolded protein GO:0034620 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an unfolded protein stimulus.	2	P38532 (/ISO) P38532 (/ISO)
Cellular protein-containing complex assembly GO:0034622 The aggregation, arrangement and bonding together of a set of components to form a protein complex, occurring at the level of an individual cell.	2	P38532 (/ISO) P38532 (/ISO)
Positive regulation of multicellular organism growth GO:0040018 Any process that activates or increases the frequency, rate or extent of growth of an organism to reach its usual body size.	2	P38532 (/IMP) P38532 (/IMP)
Positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 Any process that activates or increases the frequency, rate or extent of the introduction of a phosphate group to a tyrosine residue of a STAT (Signal Transducer and Activator of Transcription) protein.	2	P38532 (/ISO) P38532 (/ISO)
Camera-type eye development GO:0043010 The process whose specific outcome is the progression of the camera-type eye over time, from its formation to the mature structure. The camera-type eye is an organ of sight that receives light through an aperture and focuses it through a lens, projecting it on a photoreceptor field.	2	Q9R0L1 (/IMP) Q9R0L1 (/IMP)
Positive regulation of cysteine-type endopeptidase activity involved in apoptotic process GO:0043280 Any process that activates or increases the activity of a cysteine-type endopeptidase involved in the apoptotic process.	2	P38532 (/ISO) P38532 (/ISO)
Regulation of protein heterodimerization activity GO:0043497 Any process that modulates the frequency, rate or extent of protein heterodimerization, interacting selectively with a nonidentical protein to form a heterodimer.	2	P38532 (/ISO) P38532 (/ISO)
Positive regulation of cell differentiation GO:0045597 Any process that activates or increases the frequency, rate or extent of cell differentiation.	2	Q9R0L1 (/IMP) Q9R0L1 (/IMP)
Positive regulation of mitotic cell cycle GO:0045931 Any process that activates or increases the rate or extent of progression through the mitotic cell cycle.	2	P38532 (/ISO) P38532 (/ISO)
Cell development GO:0048468 The process whose specific outcome is the progression of the cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate.	2	Q9R0L1 (/IMP) Q9R0L1 (/IMP)
Protein stabilization GO:0050821 Any process involved in maintaining the structure and integrity of a protein and preventing it from degradation or aggregation.	2	A0A1D5PC94 (/IMP) P38530 (/IMP)
Protein homooligomerization GO:0051260 The process of creating protein oligomers, compounds composed of a small number, usually between three and ten, of identical component monomers. Oligomers may be formed by the polymerization of a number of monomers or the depolymerization of a large protein polymer.	2	A0A096MK39 (/IDA) Q00613 (/IDA)
Protein homooligomerization GO:0051260 The process of creating protein oligomers, compounds composed of a small number, usually between three and ten, of identical component monomers. Oligomers may be formed by the polymerization of a number of monomers or the depolymerization of a large protein polymer.	2	P38532 (/ISO) P38532 (/ISO)
Maintenance of protein location in nucleus GO:0051457 Any process in which a protein is maintained in the nucleus and prevented from moving elsewhere. These include sequestration within the nucleus, protein stabilization to prevent transport elsewhere and the active retrieval of proteins that escape the nucleus.	2	A0A060W590 (/IMP) Q8AWA0 (/IMP)
Embryonic process involved in female pregnancy GO:0060136 A reproductive process occurring in the embryo or fetus that allows the embryo or fetus to develop within the mother.	2	P38532 (/IMP) P38532 (/IMP)
Positive regulation of transcription from RNA polymerase II promoter in response to heat stress GO:0061408 Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism.	2	P38532 (/ISO) P38532 (/ISO)
Regulation of establishment of protein localization to chromosome GO:0070202 Any process that modulates the frequency, rate or extent of the directed movement of a protein to a specific location on a chromosome.	2	P10961 (/IMP) P10961 (/IMP)
Protein homotrimerization GO:0070207 The formation of a protein homotrimer, a macromolecular structure consisting of three noncovalently associated identical subunits.	2	P38532 (/ISO) P38532 (/ISO)
Protein heterotrimerization GO:0070208 The formation of a protein heterotrimer, a macromolecular structure consisting of three noncovalently associated subunits, of which not all are identical.	2	Q76M53 (/IDA) Q76M54 (/IDA)
Cellular response to hydrogen peroxide GO:0070301 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydrogen peroxide (H2O2) stimulus.	2	P38532 (/ISO) P38532 (/ISO)
Lens fiber cell differentiation GO:0070306 The process in which a relatively unspecialized cell acquires specialized features of a lens fiber cell, any of the elongated, tightly packed cells that make up the bulk of the mature lens in the camera-type eye. The cytoplasm of a lens fiber cell is devoid of most intracellular organelles including the cell nucleus, and contains primarily crystallins, a group of water-soluble proteins expressed in vary large quantities.	2	A0A2R8QAT5 (/IMP) Q5CZP2 (/IMP)
Cellular response to amino acid stimulus GO:0071230 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amino acid stimulus. An amino acid is a carboxylic acids containing one or more amino groups.	2	P38532 (/ISO) P38532 (/ISO)
Cellular response to cadmium ion GO:0071276 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cadmium (Cd) ion stimulus.	2	P38532 (/ISO) P38532 (/ISO)
Cellular response to copper ion GO:0071280 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a copper ion stimulus.	2	P38532 (/ISO) P38532 (/ISO)
Cellular response to estradiol stimulus GO:0071392 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of stimulus by estradiol, a C18 steroid hormone hydroxylated at C3 and C17 that acts as a potent estrogen.	2	P38532 (/ISO) P38532 (/ISO)
Cellular response to organic cyclic compound GO:0071407 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organic cyclic compound stimulus.	2	P38532 (/ISO) P38532 (/ISO)
Cellular response to radiation GO:0071478 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an electromagnetic radiation stimulus. Electromagnetic radiation is a propagating wave in space with electric and magnetic components. These components oscillate at right angles to each other and to the direction of propagation.	2	P38532 (/ISO) P38532 (/ISO)
Cellular response to gamma radiation GO:0071480 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gamma radiation stimulus. Gamma radiation is a form of electromagnetic radiation (EMR) or light emission of a specific frequency produced from sub-atomic particle interaction, such as electron-positron annihilation and radioactive decay. Gamma rays are generally characterized as EMR having the highest frequency and energy, and also the shortest wavelength, within the electromagnetic radiation spectrum.	2	P38532 (/ISO) P38532 (/ISO)
Cellular response to diamide GO:0072738 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a diamide (N,N,N',N'-tetramethyldiazene-1,2-dicarboxamide) stimulus.	2	P38532 (/ISO) P38532 (/ISO)
Negative regulation of inclusion body assembly GO:0090084 Any process that decreases the rate, frequency, or extent of inclusion body assembly. Inclusion body assembly is the aggregation, arrangement and bonding together of a set of components to form an inclusion body.	2	P38532 (/ISO) P38532 (/ISO)
Positive regulation of inclusion body assembly GO:0090261 Any process that increases the rate, frequency, or extent of inclusion body assembly. Inclusion body assembly is the aggregation, arrangement and bonding together of a set of components to form an inclusion body.	2	P38532 (/ISO) P38532 (/ISO)
Positive regulation of cold-induced thermogenesis GO:0120162 Any process that activates or increases the frequency, rate or extent of cold-induced thermogenesis.	2	P38532 (/IMP) P38532 (/IMP)
Positive regulation of cold-induced thermogenesis GO:0120162 Any process that activates or increases the frequency, rate or extent of cold-induced thermogenesis.	2	F1MAF1 (/ISS) Q00613 (/ISS)
Regulation of cellular response to heat GO:1900034 Any process that modulates the frequency, rate or extent of cellular response to heat.	2	P38532 (/ISO) P38532 (/ISO)
Positive regulation of mRNA polyadenylation GO:1900365 Any process that activates or increases the frequency, rate or extent of mRNA polyadenylation.	2	P38532 (/ISO) P38532 (/ISO)
Negative regulation of neuron death GO:1901215 Any process that stops, prevents or reduces the frequency, rate or extent of neuron death.	2	P38532 (/ISO) P38532 (/ISO)
Positive regulation of apoptotic DNA fragmentation GO:1902512 Any process that activates or increases the frequency, rate or extent of apoptotic DNA fragmentation.	2	P38532 (/ISO) P38532 (/ISO)
Regulation of lens fiber cell differentiation GO:1902746 Any process that modulates the frequency, rate or extent of lens fiber cell differentiation.	2	A0A2R8QAT5 (/IMP) Q5CZP2 (/IMP)
Positive regulation of cell cycle G2/M phase transition GO:1902751 Any signalling pathway that activates or increases the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G2 phase to M phase of the cell cycle.	2	P38529 (/IMP) P38531 (/IMP)
Positive regulation of cell cycle G1/S phase transition GO:1902808 Any signalling pathway that activates or increases the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G1 phase to S phase of the cell cycle.	2	P38529 (/IMP) P38531 (/IMP)
Response to sodium arsenite GO:1903935 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a sodium arsenite stimulus.	2	A0A1D5PC94 (/IMP) P38530 (/IMP)
Cellular response to sodium arsenite GO:1903936 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a sodium arsenite stimulus.	2	P38532 (/ISO) P38532 (/ISO)
Negative regulation of TORC1 signaling GO:1904262 Any process that stops, prevents or reduces the frequency, rate or extent of TORC1 signaling.	2	P10961 (/IMP) P10961 (/IMP)
Cellular response to angiotensin GO:1904385 \Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an angiotensin stimulus. Angiotensin is any of three physiologically active peptides (angiotensin II, III, or IV) processed from angiotensinogen.\	2	P38532 (/ISO) P38532 (/ISO)
Positive regulation of microtubule binding GO:1904528 Any process that activates or increases the frequency, rate or extent of microtubule binding.	2	P38532 (/ISO) P38532 (/ISO)
Negative regulation of double-strand break repair via nonhomologous end joining GO:2001033 Any process that stops, prevents or reduces the frequency, rate or extent of double-strand break repair via nonhomologous end joining.	2	P38532 (/ISO) P38532 (/ISO)
Negative regulation of transcription by RNA polymerase II GO:0000122 Any process that stops, prevents, or reduces the frequency, rate or extent of transcription mediated by RNA polymerase II.	1	Q00613 (/IDA)
MAPK cascade GO:0000165 An intracellular protein kinase cascade containing at least a MAPK, a MAPKK and a MAP3K. The cascade can also contain an additional tiers: the upstream MAP4K. The kinases in each tier phosphorylate and activate the kinase in the downstream tier to transmit a signal within a cell.	1	Q00613 (/IDA)
Regulation of transcription, DNA-templated GO:0006355 Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.	1	Q9R120 (/NAS)
Defense response GO:0006952 Reactions, triggered in response to the presence of a foreign body or the occurrence of an injury, which result in restriction of damage to the organism attacked or prevention/recovery from the infection caused by the attack.	1	F1MAF1 (/IDA)
Spermatogenesis GO:0007283 The process of formation of spermatozoa, including spermatocytogenesis and spermiogenesis.	1	P38533 (/IMP)
Response to nutrient GO:0007584 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nutrient stimulus.	1	F1MAF1 (/IEP)
MRNA transcription GO:0009299 The cellular synthesis of messenger RNA (mRNA) from a DNA template.	1	Q00613 (/IDA)
Response to organonitrogen compound GO:0010243 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organonitrogen stimulus. An organonitrogen compound is formally a compound containing at least one carbon-nitrogen bond.	1	F1MAF1 (/IEP)
Negative regulation of gene expression GO:0010629 Any process that decreases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.	1	F1MAF1 (/IMP)
Negative regulation of cardiac muscle cell apoptotic process GO:0010667 Any process that decreases the rate or extent of cardiac cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a cardiac muscle cell and result in its death.	1	F1MAF1 (/IMP)
Response to organic cyclic compound GO:0014070 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organic cyclic compound stimulus.	1	F1MAF1 (/IEP)
Response to activity GO:0014823 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an activity stimulus.	1	F1MAF1 (/IEP)
Regulation of fever generation GO:0031620 Any process that modulates the rate or extent of fever generation.	1	P38531 (/IMP)
Response to estradiol GO:0032355 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of stimulus by estradiol, a C18 steroid hormone hydroxylated at C3 and C17 that acts as a potent estrogen.	1	F1MAF1 (/IDA)
Response to testosterone GO:0033574 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a testosterone stimulus.	1	F1MAF1 (/IDA)
Cellular response to unfolded protein GO:0034620 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an unfolded protein stimulus.	1	Q00613 (/IDA)
Cellular protein-containing complex assembly GO:0034622 The aggregation, arrangement and bonding together of a set of components to form a protein complex, occurring at the level of an individual cell.	1	Q00613 (/IDA)
Cellular response to drug GO:0035690 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a drug stimulus. A drug is a substance used in the diagnosis, treatment or prevention of a disease.	1	F1MAF1 (/IEP)
Cellular response to potassium ion GO:0035865 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a potassium ion stimulus.	1	F1MAF1 (/IEP)
Positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 Any process that activates or increases the frequency, rate or extent of the introduction of a phosphate group to a tyrosine residue of a STAT (Signal Transducer and Activator of Transcription) protein.	1	F1MAF1 (/IMP)
Response to amino acid GO:0043200 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amino acid stimulus. An amino acid is a carboxylic acids containing one or more amino groups.	1	F1MAF1 (/IEP)
Positive regulation of cysteine-type endopeptidase activity involved in apoptotic process GO:0043280 Any process that activates or increases the activity of a cysteine-type endopeptidase involved in the apoptotic process.	1	F1MAF1 (/IMP)
Regulation of protein heterodimerization activity GO:0043497 Any process that modulates the frequency, rate or extent of protein heterodimerization, interacting selectively with a nonidentical protein to form a heterodimer.	1	Q00613 (/IMP)
Negative regulation of transcription, DNA-templated GO:0045892 Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription.	1	A0A096MK39 (/IMP)
Positive regulation of transcription, DNA-templated GO:0045893 Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.	1	Q5AQ33 (/TAS)
Positive regulation of mitotic cell cycle GO:0045931 Any process that activates or increases the rate or extent of progression through the mitotic cell cycle.	1	Q00613 (/IMP)
Positive regulation of transcription from RNA polymerase II promoter in response to heat stress GO:0061408 Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism.	1	Q00613 (/IDA)
Cellular response to hydrogen peroxide GO:0070301 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydrogen peroxide (H2O2) stimulus.	1	F1MAF1 (/IMP)
Cellular response to lipopolysaccharide GO:0071222 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipopolysaccharide stimulus; lipopolysaccharide is a major component of the cell wall of gram-negative bacteria.	1	F1MAF1 (/IEP)
Cellular response to amino acid stimulus GO:0071230 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amino acid stimulus. An amino acid is a carboxylic acids containing one or more amino groups.	1	F1MAF1 (/IDA)
Cellular response to amino acid stimulus GO:0071230 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amino acid stimulus. An amino acid is a carboxylic acids containing one or more amino groups.	1	F1MAF1 (/IEP)
Cellular response to cadmium ion GO:0071276 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cadmium (Cd) ion stimulus.	1	Q00613 (/IDA)
Cellular response to copper ion GO:0071280 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a copper ion stimulus.	1	Q00613 (/IDA)
Cellular response to estradiol stimulus GO:0071392 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of stimulus by estradiol, a C18 steroid hormone hydroxylated at C3 and C17 that acts as a potent estrogen.	1	F1MAF1 (/IDA)
Cellular response to organic cyclic compound GO:0071407 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organic cyclic compound stimulus.	1	F1MAF1 (/IDA)
Cellular response to radiation GO:0071478 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an electromagnetic radiation stimulus. Electromagnetic radiation is a propagating wave in space with electric and magnetic components. These components oscillate at right angles to each other and to the direction of propagation.	1	F1MAF1 (/IDA)
Cellular response to gamma radiation GO:0071480 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gamma radiation stimulus. Gamma radiation is a form of electromagnetic radiation (EMR) or light emission of a specific frequency produced from sub-atomic particle interaction, such as electron-positron annihilation and radioactive decay. Gamma rays are generally characterized as EMR having the highest frequency and energy, and also the shortest wavelength, within the electromagnetic radiation spectrum.	1	Q00613 (/IDA)
Cellular response to diamide GO:0072738 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a diamide (N,N,N',N'-tetramethyldiazene-1,2-dicarboxamide) stimulus.	1	Q00613 (/IDA)
Negative regulation of inclusion body assembly GO:0090084 Any process that decreases the rate, frequency, or extent of inclusion body assembly. Inclusion body assembly is the aggregation, arrangement and bonding together of a set of components to form an inclusion body.	1	F1MAF1 (/IMP)
Positive regulation of inclusion body assembly GO:0090261 Any process that increases the rate, frequency, or extent of inclusion body assembly. Inclusion body assembly is the aggregation, arrangement and bonding together of a set of components to form an inclusion body.	1	F1MAF1 (/IMP)
Regulation of cellular response to heat GO:1900034 Any process that modulates the frequency, rate or extent of cellular response to heat.	1	Q00613 (/IDA)
Regulation of cellular response to heat GO:1900034 Any process that modulates the frequency, rate or extent of cellular response to heat.	1	Q00613 (/TAS)
Positive regulation of cellular response to heat GO:1900036 Any process that activates or increases the frequency, rate or extent of cellular response to heat.	1	Q02953 (/IMP)
Positive regulation of mRNA polyadenylation GO:1900365 Any process that activates or increases the frequency, rate or extent of mRNA polyadenylation.	1	Q00613 (/IMP)
Negative regulation of neuron death GO:1901215 Any process that stops, prevents or reduces the frequency, rate or extent of neuron death.	1	F1MAF1 (/IMP)
Response to peptide GO:1901652 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a peptide stimulus.	1	F1MAF1 (/IEP)
Positive regulation of apoptotic DNA fragmentation GO:1902512 Any process that activates or increases the frequency, rate or extent of apoptotic DNA fragmentation.	1	F1MAF1 (/IMP)
Cellular response to sodium arsenite GO:1903936 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a sodium arsenite stimulus.	1	Q00613 (/IDA)
Cellular response to angiotensin GO:1904385 \Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an angiotensin stimulus. Angiotensin is any of three physiologically active peptides (angiotensin II, III, or IV) processed from angiotensinogen.\	1	F1MAF1 (/IDA)
Positive regulation of microtubule binding GO:1904528 Any process that activates or increases the frequency, rate or extent of microtubule binding.	1	F1MAF1 (/IMP)
Cellular response to nitroglycerin GO:1904843 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitroglycerin stimulus.	1	F1MAF1 (/IEP)
Cellular response to L-glutamine GO:1904845 Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a L-glutamine stimulus.	1	F1MAF1 (/IEP)
Response to hypobaric hypoxia GO:1990910 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating lowered oxygen tension combined with low atmospheric pressure. Hypoxia is defined as a decline in O2 levels below normoxic levels of 20.8 - 20.95% and hypobaric is defined as atmospheric pressure below 0.74 atm (greater than 2,500 m above sea level).	1	F1MAF1 (/IEP)
Response to psychosocial stress GO:1990911 Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of exposure to aversive or demanding psychological and social conditions that tax or exceed the behavioral resources of the organism.	1	F1MAF1 (/IEP)
Negative regulation of double-strand break repair via nonhomologous end joining GO:2001033 Any process that stops, prevents or reduces the frequency, rate or extent of double-strand break repair via nonhomologous end joining.	1	Q00613 (/IMP)

There are 49 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

GO Term	Annotations	Evidence
Nucleus GO:0005634 A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.	14	A0A096MK39 (/IDA) A0A1D5PC94 (/IDA) D0VYS2 (/IDA) F1MAF1 (/IDA) P10961 (/IDA) P10961 (/IDA) P38529 (/IDA) P38530 (/IDA) P38531 (/IDA) P38532 (/IDA) (4 more)
Cytoplasm GO:0005737 All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.	11	A0A1D5PC94 (/IDA) D0VYS2 (/IDA) F1MAF1 (/IDA) P38529 (/IDA) P38530 (/IDA) P38531 (/IDA) P38532 (/IDA) P38532 (/IDA) P38533 (/IDA) Q00613 (/IDA) (1 more)
Kinetochore GO:0000776 A multisubunit complex that is located at the centromeric region of DNA and provides an attachment point for the spindle microtubules.	5	P38529 (/ISS) P38532 (/ISS) P38532 (/ISS) Q08DJ8 (/ISS) Q08DJ8 (/ISS)
Nucleoplasm GO:0005654 That part of the nuclear content other than the chromosomes or the nucleolus.	5	E9PMQ6 (/IDA) Q00613 (/IDA) Q03933 (/IDA) Q03933 (/IDA) Q03933 (/IDA)
Nucleoplasm GO:0005654 That part of the nuclear content other than the chromosomes or the nucleolus.	5	P38529 (/ISS) P38532 (/ISS) P38532 (/ISS) Q08DJ8 (/ISS) Q08DJ8 (/ISS)
Centrosome GO:0005813 A structure comprised of a core structure (in most organisms, a pair of centrioles) and peripheral material from which a microtubule-based structure, such as a spindle apparatus, is organized. Centrosomes occur close to the nucleus during interphase in many eukaryotic cells, though in animal cells it changes continually during the cell-division cycle.	5	P38529 (/ISS) P38532 (/ISS) P38532 (/ISS) Q08DJ8 (/ISS) Q08DJ8 (/ISS)
PML body GO:0016605 A class of nuclear body; they react against SP100 auto-antibodies (PML, promyelocytic leukemia); cells typically contain 10-30 PML bodies per nucleus; alterations in the localization of PML bodies occurs after viral infection.	5	P38529 (/ISS) P38532 (/ISS) P38532 (/ISS) Q08DJ8 (/ISS) Q08DJ8 (/ISS)
Nuclear speck GO:0016607 A discrete extra-nucleolar subnuclear domain, 20-50 in number, in which splicing factors are seen to be localized by immunofluorescence microscopy.	5	A0A024R6X7 (/IDA) A0A024R6X7 (/IDA) E5RK26 (/IDA) Q9ULV5 (/IDA) Q9ULV5 (/IDA)
Perinuclear region of cytoplasm GO:0048471 Cytoplasm situated near, or occurring around, the nucleus.	5	P38529 (/ISS) P38532 (/ISS) P38532 (/ISS) Q08DJ8 (/ISS) Q08DJ8 (/ISS)
Nuclear stress granule GO:0097165 A dense aggregation in the nucleus composed of proteins and RNAs that appear when the cell is under stress.	5	P38529 (/ISS) P38532 (/ISS) P38532 (/ISS) Q08DJ8 (/ISS) Q08DJ8 (/ISS)
Mitotic spindle pole GO:0097431 Either of the ends of a mitotic spindle, a spindle that forms as part of mitosis, where spindle microtubules are organized; usually contains a microtubule organizing center and accessory molecules, spindle microtubules and astral microtubules.	5	P38529 (/ISS) P38532 (/ISS) P38532 (/ISS) Q08DJ8 (/ISS) Q08DJ8 (/ISS)
Nuclear chromatin GO:0000790 The ordered and organized complex of DNA, protein, and sometimes RNA, that forms the chromosome in the nucleus.	4	A0A1D5PC94 (/IDA) P38530 (/IDA) P38531 (/IDA) Q02953 (/IDA)
Ribonucleoprotein complex GO:1990904 A macromolecular complex containing both protein and RNA molecules.	4	P38532 (/ISS) P38532 (/ISS) Q08DJ8 (/ISS) Q08DJ8 (/ISS)
Nucleus GO:0005634 A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.	3	P38529 (/ISS) Q08DJ8 (/ISS) Q08DJ8 (/ISS)
Nucleoplasm GO:0005654 That part of the nuclear content other than the chromosomes or the nucleolus.	3	P38532 (/ISO) P38532 (/ISO) P38533 (/ISO)
Cytoplasm GO:0005737 All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.	3	P38529 (/ISS) Q08DJ8 (/ISS) Q08DJ8 (/ISS)
PML body GO:0016605 A class of nuclear body; they react against SP100 auto-antibodies (PML, promyelocytic leukemia); cells typically contain 10-30 PML bodies per nucleus; alterations in the localization of PML bodies occurs after viral infection.	3	A0A060W590 (/IDA) Q00613 (/IDA) Q8AWA0 (/IDA)
Protein-DNA complex GO:0032993 A macromolecular complex containing both protein and DNA molecules.	3	P10961 (/IMP) P10961 (/IMP) P22121 (/IMP)
Kinetochore GO:0000776 A multisubunit complex that is located at the centromeric region of DNA and provides an attachment point for the spindle microtubules.	2	P38532 (/ISO) P38532 (/ISO)
Euchromatin GO:0000791 A dispersed and relatively uncompacted form of chromatin.	2	P38532 (/ISO) P38532 (/ISO)
Heterochromatin GO:0000792 A compact and highly condensed form of chromatin.	2	P38532 (/ISO) P38532 (/ISO)
Nucleus GO:0005634 A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.	2	P38532 (/ISO) P38532 (/ISO)
Cytoplasm GO:0005737 All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.	2	P38532 (/ISO) P38532 (/ISO)
Mitochondrion GO:0005739 A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.	2	P10961 (/HDA) P10961 (/HDA)
Centrosome GO:0005813 A structure comprised of a core structure (in most organisms, a pair of centrioles) and peripheral material from which a microtubule-based structure, such as a spindle apparatus, is organized. Centrosomes occur close to the nucleus during interphase in many eukaryotic cells, though in animal cells it changes continually during the cell-division cycle.	2	P38532 (/ISO) P38532 (/ISO)
Cytosol GO:0005829 The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.	2	E9PMQ6 (/IDA) Q00613 (/IDA)
Cytosol GO:0005829 The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.	2	P38532 (/ISO) P38532 (/ISO)
PML body GO:0016605 A class of nuclear body; they react against SP100 auto-antibodies (PML, promyelocytic leukemia); cells typically contain 10-30 PML bodies per nucleus; alterations in the localization of PML bodies occurs after viral infection.	2	P38532 (/ISO) P38532 (/ISO)
Nuclear speck GO:0016607 A discrete extra-nucleolar subnuclear domain, 20-50 in number, in which splicing factors are seen to be localized by immunofluorescence microscopy.	2	Q9R0L1 (/ISO) Q9R0L1 (/ISO)
Protein-containing complex GO:0032991 A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together.	2	P38532 (/IPI) P38532 (/IPI)
Pronucleus GO:0045120 The nucleus of either the ovum or the spermatozoon following fertilization. Thus, in the fertilized ovum, there are two pronuclei, one originating from the ovum, the other from the spermatozoon that brought about fertilization; they approach each other, but do not fuse until just before the first cleavage, when each pronucleus loses its membrane to release its contents.	2	P38532 (/IDA) P38532 (/IDA)
Perinuclear region of cytoplasm GO:0048471 Cytoplasm situated near, or occurring around, the nucleus.	2	P38532 (/ISO) P38532 (/ISO)
Nuclear stress granule GO:0097165 A dense aggregation in the nucleus composed of proteins and RNAs that appear when the cell is under stress.	2	P38532 (/ISO) P38532 (/ISO)
Mitotic spindle pole GO:0097431 Either of the ends of a mitotic spindle, a spindle that forms as part of mitosis, where spindle microtubules are organized; usually contains a microtubule organizing center and accessory molecules, spindle microtubules and astral microtubules.	2	P38532 (/ISO) P38532 (/ISO)
Ribonucleoprotein complex GO:1990904 A macromolecular complex containing both protein and RNA molecules.	2	P38532 (/ISO) P38532 (/ISO)
Kinetochore GO:0000776 A multisubunit complex that is located at the centromeric region of DNA and provides an attachment point for the spindle microtubules.	1	Q00613 (/IDA)
Euchromatin GO:0000791 A dispersed and relatively uncompacted form of chromatin.	1	F1MAF1 (/IDA)
Heterochromatin GO:0000792 A compact and highly condensed form of chromatin.	1	F1MAF1 (/IDA)
Nucleus GO:0005634 A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.	1	Q02953 (/HDA)
Nucleus GO:0005634 A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.	1	Q5AQ33 (/IC)
Nucleus GO:0005634 A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.	1	Q00613 (/IMP)
Nucleoplasm GO:0005654 That part of the nuclear content other than the chromosomes or the nucleolus.	1	Q00613 (/TAS)
Centrosome GO:0005813 A structure comprised of a core structure (in most organisms, a pair of centrioles) and peripheral material from which a microtubule-based structure, such as a spindle apparatus, is organized. Centrosomes occur close to the nucleus during interphase in many eukaryotic cells, though in animal cells it changes continually during the cell-division cycle.	1	Q00613 (/IDA)
Cytosol GO:0005829 The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.	1	Q02953 (/HDA)
Cytosol GO:0005829 The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.	1	Q00613 (/TAS)
Perinuclear region of cytoplasm GO:0048471 Cytoplasm situated near, or occurring around, the nucleus.	1	Q00613 (/IDA)
Nuclear stress granule GO:0097165 A dense aggregation in the nucleus composed of proteins and RNAs that appear when the cell is under stress.	1	Q00613 (/IDA)
Mitotic spindle pole GO:0097431 Either of the ends of a mitotic spindle, a spindle that forms as part of mitosis, where spindle microtubules are organized; usually contains a microtubule organizing center and accessory molecules, spindle microtubules and astral microtubules.	1	Q00613 (/IDA)
Ribonucleoprotein complex GO:1990904 A macromolecular complex containing both protein and RNA molecules.	1	Q00613 (/IDA)

CATH Superfamily 1.10.10.10

Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain

Functional Families

FunFam 27: Heat shock transcription factor 1

There are 67 GO terms relating to "molecular function"

There are 169 GO terms relating to "biological process"

There are 49 GO terms relating to "cellular component"