CATH Superfamily 1.10.10.10
Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain
The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:
"Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain
".
FunFam 10: Forkhead box P2 isoform B
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 50 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
|
23 |
P58463 (/ISS)
Q2LEZ0 (/ISS)
Q4VYR7 (/ISS)
Q4VYS1 (/ISS)
Q5QL03 (/ISS)
Q5W1J5 (/ISS)
Q6BBQ1 (/ISS)
Q6QBA5 (/ISS)
Q6S511 (/ISS)
Q6U8D7 (/ISS)
(13 more) |
DNA binding GO:0003677
Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
|
19 |
P58463 (/ISS)
Q4VYR7 (/ISS)
Q4VYS1 (/ISS)
Q5QL03 (/ISS)
Q5W1J5 (/ISS)
Q6QBA5 (/ISS)
Q6S511 (/ISS)
Q6U8D7 (/ISS)
Q6U8D7 (/ISS)
Q8HZ00 (/ISS)
(9 more) |
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
19 |
O15409 (/IPI)
P58462 (/IPI)
P58463 (/IPI)
Q5W1J5 (/IPI)
Q8IVH2 (/IPI)
Q99JB6 (/IPI)
Q99JB6 (/IPI)
Q9BZS1 (/IPI)
Q9H334 (/IPI)
Q9H334 (/IPI)
(9 more) |
DNA-binding transcription factor activity, RNA polymerase II-specific GO:0000981
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.
|
14 |
O15409 (/ISA)
Q8IVH2 (/ISA)
Q9BZS1 (/ISA)
Q9H334 (/ISA)
Q9H334 (/ISA)
Q9H334 (/ISA)
Q9H334 (/ISA)
Q9H334 (/ISA)
Q9H334 (/ISA)
Q9H334 (/ISA)
(4 more) |
DNA-binding transcription factor activity, RNA polymerase II-specific GO:0000981
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.
|
14 |
O15409 (/ISM)
Q8IVH2 (/ISM)
Q9BZS1 (/ISM)
Q9H334 (/ISM)
Q9H334 (/ISM)
Q9H334 (/ISM)
Q9H334 (/ISM)
Q9H334 (/ISM)
Q9H334 (/ISM)
Q9H334 (/ISM)
(4 more) |
DNA-binding transcription factor activity, RNA polymerase II-specific GO:0000981
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.
|
12 |
O15409 (/NAS)
Q9H334 (/NAS)
Q9H334 (/NAS)
Q9H334 (/NAS)
Q9H334 (/NAS)
Q9H334 (/NAS)
Q9H334 (/NAS)
Q9H334 (/NAS)
Q9H334 (/NAS)
Q9H334 (/NAS)
(2 more) |
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
|
12 |
O15409 (/IPI)
Q9H334 (/IPI)
Q9H334 (/IPI)
Q9H334 (/IPI)
Q9H334 (/IPI)
Q9H334 (/IPI)
Q9H334 (/IPI)
Q9H334 (/IPI)
Q9H334 (/IPI)
Q9H334 (/IPI)
(2 more) |
Protein self-association GO:0043621
Interacting selectively and non-covalently with a domain within the same polypeptide.
|
11 |
Q9H334 (/IMP)
Q9H334 (/IMP)
Q9H334 (/IMP)
Q9H334 (/IMP)
Q9H334 (/IMP)
Q9H334 (/IMP)
Q9H334 (/IMP)
Q9H334 (/IMP)
Q9H334 (/IMP)
Q9H334 (/IMP)
(1 more) |
Androgen receptor binding GO:0050681
Interacting selectively and non-covalently with an androgen receptor.
|
11 |
Q9H334 (/IDA)
Q9H334 (/IDA)
Q9H334 (/IDA)
Q9H334 (/IDA)
Q9H334 (/IDA)
Q9H334 (/IDA)
Q9H334 (/IDA)
Q9H334 (/IDA)
Q9H334 (/IDA)
Q9H334 (/IDA)
(1 more) |
DNA-binding transcription factor activity GO:0003700
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons.
|
6 | O15409 (/IDA) P58462 (/IDA) P58463 (/IDA) Q99JB6 (/IDA) Q99JB6 (/IDA) Q9BZS1 (/IDA) |
Showing 1 to 10 of 50 entries
There are 223 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Negative regulation of transcription, DNA-templated GO:0045892
Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription.
|
17 |
O15409 (/IDA)
P58462 (/IDA)
P58463 (/IDA)
Q99JB6 (/IDA)
Q99JB6 (/IDA)
Q9BZS1 (/IDA)
Q9H334 (/IDA)
Q9H334 (/IDA)
Q9H334 (/IDA)
Q9H334 (/IDA)
(7 more) |
Caudate nucleus development GO:0021757
The progression of the caudate nucleus over time from its initial formation until its mature state. The caudate nucleus is the C-shaped structures of the striatum containing input neurons involved with control of voluntary movement in the brain.
|
15 |
P58463 (/ISS)
Q4VYS1 (/ISS)
Q5QL03 (/ISS)
Q6QBA5 (/ISS)
Q6S511 (/ISS)
Q8HZ00 (/ISS)
Q8HZ00 (/ISS)
Q8HZ00 (/ISS)
Q8MJ97 (/ISS)
Q8MJ98 (/ISS)
(5 more) |
Putamen development GO:0021758
The progression of the putamen over time from its initial formation until its mature state. The putamen is the lens-shaped basal ganglion involved with control of voluntary movement in the brain.
|
15 |
P58463 (/ISS)
Q4VYS1 (/ISS)
Q5QL03 (/ISS)
Q6QBA5 (/ISS)
Q6S511 (/ISS)
Q8HZ00 (/ISS)
Q8HZ00 (/ISS)
Q8HZ00 (/ISS)
Q8MJ97 (/ISS)
Q8MJ98 (/ISS)
(5 more) |
Negative regulation of gene expression GO:0010629
Any process that decreases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.
|
13 |
Q99JB6 (/IDA)
Q99JB6 (/IDA)
Q9H334 (/IDA)
Q9H334 (/IDA)
Q9H334 (/IDA)
Q9H334 (/IDA)
Q9H334 (/IDA)
Q9H334 (/IDA)
Q9H334 (/IDA)
Q9H334 (/IDA)
(3 more) |
Negative regulation of transcription, DNA-templated GO:0045892
Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription.
|
12 |
Q9BZS1 (/IMP)
Q9H334 (/IMP)
Q9H334 (/IMP)
Q9H334 (/IMP)
Q9H334 (/IMP)
Q9H334 (/IMP)
Q9H334 (/IMP)
Q9H334 (/IMP)
Q9H334 (/IMP)
Q9H334 (/IMP)
(2 more) |
Negative regulation of B cell apoptotic process GO:0002903
Any process that stops, prevents, or reduces the frequency, rate, or extent of B cell apoptotic process.
|
11 |
Q9H334 (/IDA)
Q9H334 (/IDA)
Q9H334 (/IDA)
Q9H334 (/IDA)
Q9H334 (/IDA)
Q9H334 (/IDA)
Q9H334 (/IDA)
Q9H334 (/IDA)
Q9H334 (/IDA)
Q9H334 (/IDA)
(1 more) |
Cellular response to DNA damage stimulus GO:0006974
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to its DNA from environmental insults or errors during metabolism.
|
11 |
Q9H334 (/IMP)
Q9H334 (/IMP)
Q9H334 (/IMP)
Q9H334 (/IMP)
Q9H334 (/IMP)
Q9H334 (/IMP)
Q9H334 (/IMP)
Q9H334 (/IMP)
Q9H334 (/IMP)
Q9H334 (/IMP)
(1 more) |
Positive regulation of endothelial cell migration GO:0010595
Any process that increases the rate, frequency, or extent of the orderly movement of an endothelial cell into the extracellular matrix to form an endothelium.
|
11 |
Q9H334 (/IMP)
Q9H334 (/IMP)
Q9H334 (/IMP)
Q9H334 (/IMP)
Q9H334 (/IMP)
Q9H334 (/IMP)
Q9H334 (/IMP)
Q9H334 (/IMP)
Q9H334 (/IMP)
Q9H334 (/IMP)
(1 more) |
Osteoclast differentiation GO:0030316
The process in which a relatively unspecialized monocyte acquires the specialized features of an osteoclast. An osteoclast is a specialized phagocytic cell associated with the absorption and removal of the mineralized matrix of bone tissue.
|
11 |
Q9H334 (/IDA)
Q9H334 (/IDA)
Q9H334 (/IDA)
Q9H334 (/IDA)
Q9H334 (/IDA)
Q9H334 (/IDA)
Q9H334 (/IDA)
Q9H334 (/IDA)
Q9H334 (/IDA)
Q9H334 (/IDA)
(1 more) |
Response to lipopolysaccharide GO:0032496
Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipopolysaccharide stimulus; lipopolysaccharide is a major component of the cell wall of gram-negative bacteria.
|
11 |
Q9H334 (/IDA)
Q9H334 (/IDA)
Q9H334 (/IDA)
Q9H334 (/IDA)
Q9H334 (/IDA)
Q9H334 (/IDA)
Q9H334 (/IDA)
Q9H334 (/IDA)
Q9H334 (/IDA)
Q9H334 (/IDA)
(1 more) |
Showing 1 to 10 of 223 entries
There are 15 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
|
28 |
A0A0B4J2F3 (/IDA)
A0A0B4J2F3 (/IDA)
A0A0C4DFW6 (/IDA)
B7ZLG1 (/IDA)
H0Y882 (/IDA)
Q548T7 (/IDA)
Q548T7 (/IDA)
Q548T7 (/IDA)
Q548T7 (/IDA)
Q548T7 (/IDA)
(18 more) |
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
17 |
E3VW73 (/IDA)
P58462 (/IDA)
Q498D1 (/IDA)
Q99JB6 (/IDA)
Q99JB6 (/IDA)
Q9BZS1 (/IDA)
Q9H334 (/IDA)
Q9H334 (/IDA)
Q9H334 (/IDA)
Q9H334 (/IDA)
(7 more) |
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
|
12 |
Q9BZS1 (/TAS)
Q9H334 (/TAS)
Q9H334 (/TAS)
Q9H334 (/TAS)
Q9H334 (/TAS)
Q9H334 (/TAS)
Q9H334 (/TAS)
Q9H334 (/TAS)
Q9H334 (/TAS)
Q9H334 (/TAS)
(2 more) |
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
11 |
A0A060XHH6 (/ISS)
A4IFD2 (/ISS)
E4W7U4 (/ISS)
E4W7U5 (/ISS)
Q2LEZ0 (/ISS)
Q498D1 (/ISS)
Q6BBQ1 (/ISS)
Q6U8D7 (/ISS)
Q6U8D7 (/ISS)
Q99JB6 (/ISS)
(1 more) |
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
4 | Q498D1 (/IDA) Q99JB6 (/IDA) Q99JB6 (/IDA) Q9BZS1 (/IDA) |
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
3 | P58462 (/ISO) Q99JB6 (/ISO) Q99JB6 (/ISO) |
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
3 | Q4VYR7 (/NAS) Q4VYS1 (/NAS) Q5W1J5 (/NAS) |
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
3 | P58462 (/ISO) Q99JB6 (/ISO) Q99JB6 (/ISO) |
Cell body GO:0044297
The portion of a cell bearing surface projections such as axons, dendrites, cilia, or flagella that includes the nucleus, but excludes all cell projections.
|
3 | K4EPC4 (/IDA) Q6QBA5 (/IDA) Q6TKS2 (/IDA) |
Perinuclear region of cytoplasm GO:0048471
Cytoplasm situated near, or occurring around, the nucleus.
|
3 | A0A060XHH6 (/ISS) E4W7U4 (/ISS) E4W7U5 (/ISS) |
Showing 1 to 10 of 15 entries