CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
1 | Mainly Alpha |
|
1.10 | Orthogonal Bundle |
|
1.10.150 | DNA polymerase; domain 1 |
|
1.10.150.190 | Translation initiation factor 2; subunit 1; domain 2 |
Domain Context
CATH Clusters
| Superfamily | Translation initiation factor 2; subunit 1; domain 2 |
| Functional Family | Translation initiation factor 2, alpha subunit |
Enzyme Information
UniProtKB Entries (2)
| P56287 |
EI2BE_SCHPO
Schizosaccharomyces pombe 972h-
Probable translation initiation factor eIF-2B subunit epsilon
|
| P20459 |
IF2A_YEAST
Saccharomyces cerevisiae S288C
Eukaryotic translation initiation factor 2 subunit alpha
|
PDB Structure
| PDB | 6JLZ |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Structural basis for eIF2B inhibition in integrated stress response.
Science
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