CATH Domain 6fwbC01

Level	CATH Code	Description
	3	Alpha Beta
	3.30	2-Layer Sandwich
	3.30.300	GMP Synthetase; Chain A, domain 3
	3.30.300.10

Superfamily	3.30.300.10
Functional Family	S-adenosylmethionine synthase

2.5.1.6

Methionine adenosyltransferase.

based on mapping to UniProt P31153

ATP + L-methionine + H(2)O = phosphate + diphosphate + S-adenosyl-L- methionine.

-!- Formerly EC 2.4.2.13.

METK2_HUMAN

Homo sapiens

S-adenosylmethionine synthase isoform type-2

PDB	6FWB
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Identification of a natural inhibitor of methionine adenosyltransferase 2A regulating one-carbon metabolism in keratinocytes. Bai, J., Gao, Y., Chen, L., Yin, Q., Lou, F., Wang, Z., Xu, Z., Zhou, H., Li, Q., Cai, W., Sun, Y., Niu, L., Wang, H., Wei, Z., Lu, S., Zhou, A., Zhang, J., Wang, H. Ebiomedicine