CATH Domain 6erfE02

CATH Classification

Level	CATH Code	Description
	2	Mainly Beta
	2.40	Beta Barrel
	2.40.290	Ku70; Chain: A; Domain 2
	2.40.290.10

Domain Context

CATH Clusters

Superfamily	2.40.290.10
Functional Family	X-ray repair cross-complementing protein 6

Enzyme Information

4.2.99.-	Other carbon-oxygen lyases. based on mapping to UniProt P12956
3.6.4.-	Acting on ATP; involved in cellular and subcellular movement. based on mapping to UniProt P12956

UniProtKB Entries (1)

XRCC5_HUMAN

Homo sapiens

X-ray repair cross-complementing protein 5

PDB Structure

PDB	6ERF
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	XLF and APLF bind Ku80 at two remote sites to ensure DNA repair by non-homologous end joining. Nemoz, C., Ropars, V., Frit, P., Gontier, A., Drevet, P., Yu, J., Guerois, R., Pitois, A., Comte, A., Delteil, C., Barboule, N., Legrand, P., Baconnais, S., Yin, Y., Tadi, S., Barbet-Massin, E., Berger, I., Le Cam, E., Modesti, M., Rothenberg, E., Calsou, P., Charbonnier, J.B. Nat. Struct. Mol. Biol.