CATH Domain 6cwzD03

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.10	Roll
	3.10.290	Structural Genomics Hypothetical 15.5 Kd Protein In mrcA-pckA Intergenic Region; Chain A
	3.10.290.20	Ubiquitin-like 2 activating enzyme e1b. Chain: B, domain 3

Domain Context

CATH Clusters

Superfamily	Ubiquitin-like 2 activating enzyme e1b. Chain: B, domain 3
Functional Family	SUMO-activating enzyme subunit 2

Enzyme Information

2.3.2.-

Aminoacyltransferases.

based on mapping to UniProt Q9UBT2

UniProtKB Entries (1)

SAE2_HUMAN

Homo sapiens

SUMO-activating enzyme subunit 2

PDB Structure

PDB	6CWZ
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Molecular mechanism of a covalent allosteric inhibitor of SUMO E1 activating enzyme. Lv, Z., Yuan, L., Atkison, J.H., Williams, K.M., Vega, R., Sessions, E.H., Divlianska, D.B., Davies, C., Chen, Y., Olsen, S.K. Nat Commun